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2981
Z-Guggulsterone Induces Apoptosis in Gastric Cancer Cells through the Intrinsic Mitochondria-Dependent Pathway
Published 2021-01-01“…Inhibition of FXR signaling with z-guggulsterone dose-dependently inhibited SGC-7901 cell proliferation and promoted SGC-7901 cell apoptosis. Bcl-2 protein expression was significantly decreased, and active caspase-3 and Bax protein expression was increased in SGC-7901 cells incubated with z-guggulsterone. …”
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2982
Ultra-processed foods and plant-based alternatives impair nutritional quality of omnivorous and plant-forward dietary patterns in college students
Published 2025-02-01“…UPF exhibited a lower content of protein, fiber, vitamin B2, vitamin B12, folate, zinc and calcium compared to processed foods (all p < 0.001). …”
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2983
Cloning, expression pattern analysis, and vector construction of the BvNAC40 gene in sugar beet
Published 2025-01-01“…[Methods] BvNAC40 gene was cloned using the PCR method, and its protein structure was analyzed by bioinformatics methods. …”
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2984
Purpurogallin, a Natural Phenol, Attenuates High-Mobility Group Box 1 in Subarachnoid Hemorrhage Induced Vasospasm in a Rat Model
Published 2014-01-01“…Purpurgallin dose-dependently reduced HMGB1 protein expression. Likewise, high dose purpurogallin reduced TNF-α and HMGB1 mRNA levels. …”
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2985
Analisis Efisiensi Box Fermentasi Oncom Tahu dengan Sistem Arduino
Published 2022-04-01“…Tofu pulp still has a relatively high protein content because in the process of making tofu not all protein content is extracted, especially when using a simple and traditional milling process. …”
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2986
Effect of Tick and Lice on Some Blood Constitute and Trace elements of Local Black Goat in Sulaimani, Kurdistan Region of Iraq
Published 2018-12-01“…Biochemical values (serum proteins and some trace elements) analyzed, in infested goats emerges decline in serum protein value 7.12±0.08 µg/dl, albumin value 4.12±0.03 µg/dl and increase of globulin value 3.04±0.09 µg/dl, in serum protein and globulin values shows not significance differences, while described highly significance differences in albumin value at p?…”
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2987
Construction of Two mCherry Plasmids (pXG-mCherry) for Transgenic Leishmania: Valuable Tools for Future Molecular Analysis
Published 2017-01-01“…We have constructed two plasmids expressing the red fluorescent protein mCherry with multiple cloning sites (MCS), adequate for N- and C-terminal fusion protein constructs. …”
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2988
Molecular basis for azetidine-2-carboxylic acid biosynthesis
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2989
Extracellular Vesicles of Mesenchymal Stem Cells Are More Effectively Accessed through Polyethylene Glycol-Based Precipitation than by Ultracentrifugation
Published 2022-01-01“…There was no difference in morphology, size, or specific marker-positive ratio of PEG-EVs and UC-EVs, but PEG obtained more EV particles, protein, and RNA than the UC method. In our THP-1 model of LPS induction, MSC-EVs did not lead to a change in protein expression but inhibited the LPS-induced increase in cytokine secretion. …”
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2990
Prion meeting 2023: implications of a growing field
Published 2024-12-01“…The prion concept has been more recently expanded to refer to misfolded proteins that are capable of converting a normal form of a protein into an abnormal form. …”
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2991
Genome-wide DNA methylation and transcriptome sequencing analyses of lens tissue in an age-related mouse cataract model.
Published 2025-01-01“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) functional enrichment analyses showed that DEGs with abnormal methylation at CCGG sites were primarily associated with protein kinase C signaling (Akap12, Capzb), protein threonine kinase activity (Dmpk, Mapkapk3), and calcium signaling pathway (Slc25a4, Cacna1f), whereas DEGs with abnormal methylation at CCWGG sites were associated with ribosomal protein S6 kinase activity (Rps6ka3). …”
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2992
Dexmedetomidine Inhibits Voltage-Gated Sodium Channels via α2-Adrenoceptors in Trigeminal Ganglion Neurons
Published 2018-01-01“…Dexmedetomidine-induced inhibition of INa was mediated by G protein-coupled receptors (GPCRs) as this effect was blocked by intracellular perfusion with the G protein inhibitor GDPβ-S. …”
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2993
Assessment of the Efficacy of L-Lysine Sulfate vis-à-vis L-Lysine Hydrochloride as Sources of Supplemental Lysine in Broiler Chickens
Published 2010-01-01“…Supplementation of lysine to the basal diet improved breast meat yield (𝑃<.05). Meat protein content and protein accretion increased (𝑃<.01) when L-lysine sulfate was supplemented. …”
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2994
Spinal Involvement of TRPV1 and PI3K/AKT/mTOR Pathway During Chronic Postoperative Pain in Mice
Published 2025-01-01“…TRPV1 and PI3K/AKT/mTOR protein levels were evaluated by Western blotting. …”
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2995
Biocomposite Polyvinyl Alcohol/Ferritin Hydrogels with Enhanced Stretchability and Conductivity for Flexible Strain Sensors
Published 2025-01-01“…Protein-based hydrogels with stretchability and conductivity have potential applications in wearable electronic devices. …”
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2996
Lipoxin A4 Reduces Ventilator-Induced Lung Injury in Rats with Large-Volume Mechanical Ventilation
Published 2020-01-01“…The oxidative stress response, lung tissue injury, and apoptosis in lung tissue were also estimated, and the expression of apoptotic proteins was examined. MV worsened all of the indices compared to the sham group. …”
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2997
Evolution of the Macrophage CD163 Phenotype and Cytokine Profiles in a Human Model of Resolving Inflammation
Published 2013-01-01“…Multiplex cytokine analysis demonstrated that monocyte chemoattractant protein (MCP-1/CCL2), interleukin- (IL-) 6, IL-8/CXCL8, macrophage inflammatory protein (MIP1α/CCL3), MIP-1β/CCL4, tumor necrosis factor- (TNF-) α, and eotaxin (CCL11) were all significantly upregulated at 16 h compared with 40 h. …”
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2998
Prioritization of causal genes from genome-wide association studies by Bayesian data integration across loci.
Published 2025-01-01“…The SigNet method builds on existing methods that focus on individual loci with evidence from gene distance and expression quantitative trait loci (eQTL) by sharing information across loci using protein-protein and gene regulatory interaction network data. …”
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2999
Expression Pattern of a Homeotic Gene, HOXA5, in Normal Breast and in Breast Tumors
Published 2006-01-01“…However, nearly 70% of all breast carcinomas had decreased HOXA5 protein levels as compared to normal breast tissues. …”
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3000
Proteomic Analysis of the Vitreous following Experimental Retinal Detachment in Rabbits
Published 2015-01-01“…Here we investigate the protein profile of the vitreous following experimental retinal detachment using a comparative proteomic based approach. …”
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