Analysis of Argonaute Complex Bound mRNAs in DU145 Prostate Carcinoma Cells Reveals New miRNA Target Genes by Jaroslaw Szczyrba, Volker Jung, Michaela Beitzinger, Elke Nolte, Sven Wach, Martin Hart, Sandra Sapich, Marc Wiesehöfer, Helge Taubert, Gunther Wennemuth, Norbert Eichner, Thomas Stempfl, Bernd Wullich, Gunter Meister, Friedrich A. Grässer

“…We demonstrate that the mRNAs of the death effector domain-containing protein (DEDD), the tumor necrosis factor receptor superfamily, member 10b protein (TNFRSF10B), the tumor protein p53 inducible nuclear protein 1 (TP53INP1), and the secreted protein, acidic, cysteine-rich (SPARC; osteonectin) are regulated by miRNAs miR-148a, miR-20a, miR-24, and miR-29a/b, respectively. …”
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Diamond Blackfan Anemia at the Crossroad between Ribosome Biogenesis and Heme Metabolism by Deborah Chiabrando, Emanuela Tolosano

“…Moreover, mutations in other ribosomal protein coding genes account for about 25% of other DBA cases. …”
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Zinc Protoporphyrin Upregulates Heme Oxygenase-1 in PC-3 Cells via the Stress Response Pathway by Simon C. M. Kwok

“…Of all the known responsive elements in the HO-1 promoter, ZnPP activated mainly the stress response elements. Of the various protein kinase inhibitors and antioxidant tested, only Ro 31-8220 abrogated ZnPP-induced HO-1 expression, suggesting that activation of HO-1 gene by ZnPP may involve protein kinase C (PKC). …”
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Thrombomodulin: A Bifunctional Modulator of Inflammation and Coagulation in Sepsis by Takayuki Okamoto, Hironobu Tanigami, Koji Suzuki, Motomu Shimaoka

“…Thrombomodulin is an endogenous anticoagulant protein that, in cooperation with protein C and thrombin-activatable fibrinolysis inhibitor, serves to maintain the endothelial microenvironment in an anti-inflammatory and anticoagulant state. …”
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Plant-based burger patties are a source of bioaccessible iron and zinc by Jonas Pospiech, Johanita Kruger, Jan Frank

“…We therefore quantified minerals (Fe, Zn), inhibitors (phytate, oxalate, condensed tannins), and enhancers (ascorbic acid, carotenoids) of mineral absorption in pea protein-, soy protein-, soy flour-, and sunflower protein-based burger patties and the resulting bioaccessibility of the contained iron and zinc conducting in vitro digestion experiments. …”
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Caveolin 3, Flotillin 1 and Influenza Virus Hemagglutinin Reside in Distinct Domains on the Sarcolemma of Skeletal Myofibers by Mika Kaakinen, Tuula Kaisto, Paavo Rahkila, Kalervo Metsikkö

“…We examined the distribution of selected raft proteins on the sarcolemma of skeletal myofibers and the role of cholesterol environment in the distribution. …”
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Targeting Anabolic Impairment in Response to Resistance Exercise in Older Adults with Mobility Impairments: Potential Mechanisms and Rehabilitation Approaches by Micah J. Drummond, Robin L. Marcus, Paul C. LaStayo

“…While a bout of resistance exercise increases protein synthesis rates in healthy young skeletal muscle, the effectiveness of resistance exercise to mount a protein synthetic response is less pronounced in older adults. …”
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A comprehensive review of Interferometric Reflectance Imaging Sensor as a sensitive detection platform and its application areas by Monireh Bakhshpour-Yucel, Nese Lortlar Unlu, Elif Seymour, Adil Denizli

“…This review explores the underlying principles, instrumentation, and diverse applications of IRIS, with a focus on its efficacy for real-time monitoring of DNA-protein and protein-protein interactions, as well as virus detection. …”
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Autoantibodies as Diagnostic Markers and Mediator of Joint Inflammation in Arthritis by Qinghua Fang, Jiaxin Ou, Kutty Selva Nandakumar

“…These autoantibodies (anticitrullinated protein/peptide antibodies (ACPAs), rheumatoid factors (RF), anticollagen type II antibodies, antiglucose-6 phosphate isomerase antibodies, anticarbamylated protein antibodies, and antiacetylated protein antibodies) have different characteristics, diagnostic/prognostic value, and pathological significance in RA patients. …”
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Exosomal insights into ovarian cancer stem cells: revealing the molecular hubs by Kiana Sojoudi, Maryam Solaimani, Hossein Azizi

“…While exosomes have been studied in various cancer types, comprehensive network analyses of exosome proteins in ovarian cancer remain limited. In this study, we used a protein-protein interaction (PPI) network. …”
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Therapeutic Strategies for Neuropathic Pain: Potential Application of Pharmacosynthetics and Optogenetics by Gum Hwa Lee, Sang Seong Kim

“…The multiple protein expressions complicate therapeutic development for neuropathic pain. …”
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Relationship between Sowing Time, Variety, and Quality in Safflower by Mehmet Oz

“…This research was carried out to determine the rates of protein and oil production and fatty acid composition and their correlation coefficients in four safflower cultivars (Remzibey, Dincer, Balci, and Yenice) sown in the autumn and spring from 2013 to 2015. …”
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Axon regeneration: an issue of translation by Schaeffer, Julia, Belin, Stephane

“…However, it is now well described that mRNA and protein levels correlate only partially in cells, and that the transcription process (from DNA to mRNA) may not directly reflect protein expression. …”
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Identification of cardiac premature senescence markers through GEO database interaction approach by Tiwuk Susantiningsih, Ani Retno Prijanti, Novi Silvia Hardiany, Fadilah

“…Results: From 1,046 proteins obtained, analyzed by using Cytoscape Tools series 3.9.1 resulted to 100 proteins having the highest score and continued with StringDB analysis with 16 proteins. …”
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The nonlinear cysteine redox dynamics in the i-space: A proteoform-centric theory of redox regulation by James N. Cobley, Panagiotis N. Chatzinikolaou, Cameron A. Schmidt

“…The post-translational redox regulation of protein function by cysteine oxidation controls diverse biological processes, from cell division to death. …”
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A combined use of Panax ginseng extract and the probiotic, Lactobacillus plantarum in the diet of Asian seabass, Lates calcarifer: Effects on growth, immunity and survival after ba... by Xiaojie Hou, Jianfeng Zhang, Neda Behmagham, Hamed Ghafarifarsani

“…This treatment also showed highest digestive enzyme activities for trypsin (5.2 ± 0.11 U/mg protein), chymotrypsin (3.9 ± 0.15 U/mg protein) and lipase (2.12 ± 0.04 U/mg protein) (P < 0.01). …”
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Surfactin alleviated hyperglycaemia in mice with type 2 diabetes induced by a high-fat diet and streptozotocin by Xiaoyu Chen, Hongyuan Zhao, Fanqiang Meng, Libang Zhou, Zhaoxin Lu, Yingjian Lu

“…According to further research, surfactin administration reduced Firmicutes-to-Bacteroidetes ratios while increasing Bifidobacterium abundance by 20 times and the level of the tight junction protein Occludin by 18.38 % and ZO-1 by 66.60 %. Furthermore, surfactin also improved hepatic glucose metabolism by activating the adenosine monophosphate-activated protein kinase (AMPK) signalling pathway, increasing glycogen synthesis and glucose transporter 2 (GLUT2) protein expression while reducing glucose-6-phosphatase (G6Pase) protein expression. …”
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Fructose 1,6-bisphosphatase 1 is a potential biomarker affecting the malignant phenotype and aerobic glycolysis in glioblastoma by Weihong Lu, Guozheng Huang, Yihan Yu, Xia Zhai, Xiangfeng Zhou

“…FBP1 knockdown in GBM cells suppressed the proliferation, invasion, migration, and aerobic glycolysis of GBM cells, lowered the phosphorylation levels of AKT and PI3K and the protein expression of BCL2 but promoted BAX protein expression. …”
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RETRACTED: LncRNA CCAT2 promotes the proliferation and metastasis of colorectal cancer through activation of the ERK and Wnt signaling pathways by regulating GNB2 expression by Jinhai Tian, Xu Cao, Zongying Jiang, Jia Wang, Wan Fan, Shaoting Zhang, Sien Zhao, Jianmin Sun

“…The interaction between CCAT2 and GNB2 protein was shown to modulate GNB2 protein alterations and affect the ERK and Wnt signaling pathways, thereby promoting CRC proliferation and metastasis. …”
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Effect of Composition and Processing Conditions on Selected Properties of Potato-Based Pellets and Microwave-Expanded Snacks Supplemented with Fresh Beetroot Pulp by Katarzyna Lisiecka, Agnieszka Wójtowicz, Agnieszka Sujak

“…This indicates that the protein structure underwent some form of ordering as the molecular interactions of the proteins intensified. …”
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