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2781
Computational design, expression, and characterization of a Plasmodium falciparum multi-epitope, multi-stage vaccine candidate (PfCTMAG)
Published 2025-01-01“…In-silico analysis revealed that the designed antigen, PfCTMAG (Plasmodium falciparum Circumsporozoite, Thrombospondin-related adhesion protein, Merozoite surface protein 2, Apical asparagine (Asn)-rich protein and Glutamate-Rich Protein), effectively bound to Toll-like receptor 4 (TLR-4) and triggered a strong immune response. …”
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2782
Nutritive value of cattle manure vermicast and its effect on in vitro ruminal gas production
Published 2024-02-01“…Vermicomposting has the potential of being used as another tool for forage treatment and addition of CMV could be expected to reduce ruminant gas production, increase ME and microbial protein synthesis.…”
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2783
Diabetic Polyneuropathy in Type 2 Diabetes Mellitus: Inflammation, Oxidative Stress, and Mitochondrial Function
Published 2016-01-01“…Inflammation induces activation of nuclear factor kappa B, activator protein 1, and mitogen-activated protein kinases. …”
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2784
Impact of Paracoccus sp. EGY7 carotenoids on triple-negative breast cancer cells: invitro study
Published 2025-02-01“…Western blotting showed increased BAX protein expression at 600 and 1200 µg compared to the control group (p < 0.001), and significantly lower BCL-2 protein expression (p = 0.000005 for 1200 µg and p = 0.0001 for 600 µg). …”
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2785
Diversity and occurrence of methylotrophic yeasts used in genetic engineering
Published 2020-04-01“…Methylotrophic yeasts have been used as the platform for expression of heterologous proteins since the 1980’s. They are highly productive and allow producing eukaryotic proteins with an acceptable glycosylation level. …”
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2786
Regulation of noradrenaline synthesis, uptake, and degradation in the left ventricle by fatty acid amide hydrolase (FAAH) inhibitor URB597 in the chronic unpredictable stress model...
Published 2024-01-01“…CUS decreased the levels of both NA and dopamine-β-hydroxylase (DBH) protein in male rats and decreased NA transporter (NET) protein levels in female rats while elevating monoamine oxidase A (MAO-A) in both sexes. …”
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2787
Comparing High-Intensity Interval Training (HIIT) and Continuous Training on Apelin, APJ, NO, and Cardiotrophin-1 in Cardiac Tissue of Diabetic Rats
Published 2020-01-01“…Moreover, APJ and CT-1 protein significantly upregulated in CO-2 and HIIT-2 compared to the other groups (p<0.01). …”
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2788
Effects of screw configuration and interfacial properties on oil incorporation in high moisture extrusion
Published 2025-01-01“…For oil addition by emulsion, several plant-based protein sources were compared as emulsifier. The choice of protein emulsifier had a strong effect on wedge length of the extrudate, the maximum linear strain and value of G′ in shear, and the rupture strength of the extrudate. …”
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2789
ABA enhances the apoptotic effect of docetaxel in the multidrug-resistant DU145 prostate cancer cell line
Published 2024-01-01“…RT-PCR analysis showed that treatment of resistant cells with 50.07 nM docetaxel and 500 μM ABA (ABA) resulted in the following changes in gene expression: heat shock protein (HSP) 70 (0.63-fold), glucose-regulated protein 94 (GRP94) 0.33-fold, inositol-requiring transmembrane kinase endoribonuclease-1α (IRE1α) 1.62-fold, ER degradation- enhancing alpha-mannosidase-like 1 (EDEM1) 1.77-fold, X-box binding protein 1 (XBP1) 1.53-fold, p21 (2.53-fold), cellular tumor antigen p53 (p53) 2.49-fold, bcl-2-like protein 4 (Bax) 2.7-fold, and tumor necrosis factor (TNF-α) 6.35-fold. …”
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2790
DNA Methylation May be Involved in the Analgesic Effect of Hyperbaric Oxygen via Regulating FUNDC1
Published 2020-01-01“…Western blotting was also used to assess expression of FUNDC1, BCL2, and adenovirus E1B19 kDa-interacting protein 3-like (NIX) and BCL2 and adenovirus E1B19 kDa-interacting protein3 (BNIP3). …”
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2791
Apoptosis Transcriptional Profile Induced by Porphyromonas gingivalis HmuY
Published 2019-01-01“…This study aimed at evaluating the transcriptional profile of apoptosis-related genes after in vitro stimulation of peripheral blood mononuclear cells (PBMCs) derived from individuals with periodontitis (P) and healthy nonperiodontitis (NP) control subjects with P. gingivalis HmuY protein. PBMCs from the P and NP groups were stimulated with HmuY P. gingivalis protein, and the expression of genes related to apoptosis was assessed by custom real-time polymerase chain reaction array (Custom RT2 PCR Array). …”
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2792
Effects of different wet distillers’ grains ratios on fermentation quality, nitrogen fractions and bacterial communities of total mixed ration silage
Published 2025-01-01“…Abstract Objective Wet distiller’s grains (WDG) are rich in crude protein, yet challenging to preserve. Nevertheless, incorporating WDG into total mixed ration (TMR) silage holds promise for enhancing fermentation quality. …”
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2793
Acyl-CoA Thioesterase 1 Contributes to Transition of Steatosis to Metabolic-Associated Steatohepatitis
Published 2024-01-01“…We used a network analysis approach to delineate protein-protein interactions that contribute to the transition from steatosis to MASH, in order to identify and target this transition as a potential pharmacotherapeutic strategy. …”
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2794
Effect of Cannabis Seeds on Some Biomedical Parameters in Male Rats
Published 2022-09-01“…Level of Cholesterol, triglyceride and c-reactive protein were significantly (p<0.05) reduced. Serum total protein, albumin and globulin were significantly (p<0.05) elevated in treatment group comparing to control group. …”
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2795
The use of citrus pulp silage in Diplodus puntazzo nutrition
Published 2018-11-01“…The control diet (CON) contained 421.6 g/kg of protein and 22.6 MJ/kg of energy. The citrus pulp diet (CPD) included 442.7 g/kg of protein and 22.02 MJ/kg of energy. …”
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2796
The Quantitative Analysis of bFGF and VEGF by ELISA in Human Meningiomas
Published 2006-01-01“…The quantitative analysis of VEGF using ELISA in various subtypes of grade I meningiomas reported higher VEGF contents in meningothelial (2.38±0.62 pg/μg protein, n=7), transitional (1.08±0.21 pg/μg protein, n=13), and microcystic meningiomas (1.98±0.87 pg/μg protein, n=5) as compared with fibrous ones (0.36±0.09 pg/μg protein, n=5). …”
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2797
Comparison of Trace Elements in High-Molecular-Mass Multiprotein Complex and in Female Milk from Which It Was Obtained
Published 2019-01-01“…Many biological processes are performed by different protein complexes. During the association of proteins and enzymes forming specific complexes, the latter can include ions of various metal ions, which may be important for their formation and biological function. …”
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2798
DUOX2 Expression Is Increased in Barrett Esophagus and Cancerous Tissues of Stomach and Colon
Published 2016-01-01“…In CRC tissues, the DUOX2 protein expression level in stages II–IV was significantly higher than that in stage I. …”
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2799
Efek berbagai pretreatment koro pedang kupas terhadap kadar HCN, proksimat dan karakteristik fisik tepung koro pedang (Canavalia ensiformis)
Published 2025-01-01“…Jack bean is one of the alternative protein sources, with a protein content of 27.4% on a dry basis. …”
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2800
Mediators of monocyte chemotaxis and matrix remodeling are associated with mortality and pulmonary fibroproliferation in patients with severe COVID-19.
Published 2024-01-01“…In mechanically ventilated patients, endotracheal aspirates (ETA) were collected. Protein concentrations were measured by immunoassay. …”
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