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2761
Non3 is an essential Drosophila gene required for proper nucleolus assembly
Published 2019-03-01“…Here, we report the characterization of the Drosophila Non3 (Novel nucleolar protein 3) gene, which encodes a protein homologous to the human Brix domain-containing Rpf2 that has been shown to control ribosomal RNA (rRNA) processing. …”
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2762
Determination of the breeding value of collection chickpea (<i>Cicer arietinum</i> L.) accessions by cluster analysis
Published 2020-05-01“…Cluster 3 consists of 3 accessions, which have large seeds and high protein content in them, give moderate yields, are highly responsive to nitrogenization and poorly resistant to Ascochyta leaf and pod spot. …”
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2763
Prediksi Interaksi Drug Target pada Gen Kanker Menggunakan Metode Lasso-XGBoost
Published 2023-07-01“…Data protein terkait kanker didapatkan dari daftar Cancer Gene Census, dari daftar tersebut dilakukan penelusuran pada database GDSC, DrugCentral, dan DrugBank untuk menghasilkan daftar senyawa obat yang berinteraksi dengan protein tersebut. …”
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2764
Integrated analysis of cell cycle and p53 signaling pathways related genes in breast, colorectal, lung, and pancreatic cancers: implications for prognosis and drug sensitivity for...
Published 2024-12-01“…Validation of hub genes at mRNA and protein levels was done via GEPIA2 and Human Protein Atlas. …”
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2765
Protective Effects of Baicalein on Lipopolysaccharide-Induced AR42J PACs through Attenuation of Both Inflammation and Pyroptosis via Downregulation of miR-224-5p/PARP1
Published 2024-01-01“…Flow cytometry was applied to evaluate the apoptotic rates of AR42J PACs. The RNA and protein expression of miR-224-5p, poly ADP-ribose polymerase-1 (PARP1), nuclear transcription factor-κB65 (NF-κB65), phospho-kappa B alpha(p-IκB-α), interleukin(IL)-18R, NOD-like receptor thermal protein domain-associated protein 3 (NLRP3), gasdermin D (GSDMD), apoptosis-associated speck-like protein containing a CARD (ASC), and caspase-1 was detected based on the WB and RT-PCR assays. …”
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2766
Phosphorylation of Bok at Ser-8 blocks its ability to suppress IP3R-mediated calcium mobilization
Published 2025-01-01“…Abstract Background Bok is a poorly characterized Bcl-2 protein family member with roles yet to be clearly defined. …”
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2767
Identification and Validation of Pivotal Genes in Osteoarthritis Combined with WGCNA Analysis
Published 2025-01-01“…Functional enrichment analyses, protein-protein interaction (PPI) analysis, and weighted gene co-expression network analysis (WGCNA) of the DEGs were performed. …”
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2768
COMPARATIVE STUDY ON PHYSICO-CHEMICAL CHANGES DURING DRY AGING OF BLACK ANGUS AND ROMANIAN SPOTTED BEEF
Published 2024-08-01“…The parameters studied were content of fat (%), content of protein (%), content of collagen (%), content of water (%) and collagen-protein ratio. …”
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2769
Detection of Complement C1q B Chain Overexpression and Its Latent Molecular Mechanisms in Cervical Cancer Tissues Using Multiple Methods
Published 2022-01-01“…The expression of C1QB protein was higher in cervical cancer samples than that in benign cervical tissue, LSIL, and HSIL samples (p<0.05). …”
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2770
Chemical tools to define and manipulate interferon-inducible Ubl protease USP18
Published 2025-01-01“…Abstract Ubiquitin-specific protease 18 (USP18) is a multifunctional cysteine protease primarily responsible for deconjugating the interferon-inducible ubiquitin-like modifier ISG15 from protein substrates. Here, we report the design and synthesis of activity-based probes (ABPs) that incorporate unnatural amino acids into the C-terminal tail of ISG15, enabling the selective detection of USP18 activity over other ISG15 cross-reactive deubiquitinases (DUBs) such as USP5 and USP14. …”
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2771
Proteomic profiling identifies upregulation of aurora kinases causing resistance to taxane-type chemotherapy in triple negative breast cancer
Published 2025-01-01“…The increase of AURKA and AURKB protein was majorly due to a post-transcription level regulation, and Paclitaxel treatment induced Aurora Kinases protein phosphorylation on AURKA(T288)/AURKB(T232) sites and their protein stability. …”
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2772
Digestive enzymes activities in Oreochromis niloticus fed diet supplemented with recombinant growth hormone
Published 2016-02-01“…The results showed that fish treated with rE1GH showed lower lipase and chymotrypsin specific activities (P>0.05), while the trypsin/chymotrypsin specific activity (T/C ratio) was found higher compared to control fish. Moreover, higher protein digestibility, higher protein retention and a lower ammonia excretion rate were measured for rE1GH treated fish. …”
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2773
Microalgae: A potential alternative to health supplementation for humans
Published 2019-03-01“…Keywords: Health, Human, Microalgae, Protein, Supplement…”
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2774
Expression of the Gene Encoding the Brucella abortus BAB1-0278 Antigen in Probiotic Lactococcus lactis Bacteria
Published 2024-10-01“…This antigen encodes a protein called GcrA, which plays an essential role in the transcription of target genes in the cell cycle. …”
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2775
PPARβ/δ Agonism with GW501516 Increases Myotube PGC-1α Content and Reduces BCAA Media Content Independent of Changes in BCAA Catabolic Enzyme Expression
Published 2023-01-01“…GW significantly increased PGC-1α protein expression, mitochondrial content, and mitochondrial function. …”
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2776
Computational identification and experimental validation of novel Saccharum officinarum microRNAs along with their targets through RT-PCR approach
Published 2025-12-01“…Accordingly, they contain fifty specific targeted proteins with substantial targets in the structural, transcriptional protein, etc. …”
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2777
Blockade of Vascular Endothelial Growth Factor Receptor 1 Prevents Inflammation and Vascular Leakage in Diabetic Retinopathy
Published 2015-01-01“…VEGFR1 blockade significantly inhibited diabetes-related vascular leakage, leukocytes-endothelial cell (EC) adhesion (or retinal leukostasis), expression of intercellular adhesion molecule- (ICAM-) 1 protein, abnormal localization and degeneration of the tight junction protein zonula occludens- (ZO-) 1, and the cell adhesion protein vascular endothelial (VE) cadherin. …”
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2778
Possible Roles of Proinflammatory and Chemoattractive Cytokines Produced by Human Fetal Membrane Cells in the Pathology of Adverse Pregnancy Outcomes Associated with Influenza Viru...
Published 2012-01-01“…Influenza virus infection induced the mRNA expression of not only the proinflammatory cytokines but also chemoattractive cytokines, such as monocyte chemoattractant protein (MCP)-1, regulated on activation, normal T-cell expressed and secreted (RANTES), macrophage inflammatory protein (MIP)-1β, IL-8, growth-regulated oncogene (GRO)-α, GRO-β, epithelial cell-derived neutrophil-activating protein (ENA)-78, and interferon inducible protein (IP)-10 in cultured chorion cells. …”
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2779
Inhibition of Androgen Receptor Expression with Small Interfering RNA Enhances Cancer Cell Apoptosis by Suppressing Survival Factors in Androgen Insensitive, Late Stage LNCaP Cells
Published 2013-01-01“…We compared expressions of AR, heat shock protein 27 (HSP27), clusterin (CLU), glucose-related protein 78 (GRP78), and cellular FLICE-like inhibitory protein (c-FLIP) and their genes between es-LNCaP (less than 33 times subcultured, L-33), ls-LNCaP (over 81 times subcultured, H-81), and si-LNCaP (AR siRNA transfected ls-LNCaP) by Western blotting and RT-PCR. …”
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2780
Expression of O6-Alkylguanine-DNA Alkyltransferase in Normal and Malignant Bladder Tissue of Egyptian Patients
Published 2010-01-01“…MGMT varied widely from 42–253 fmoles/mg protein and from 3.2–40 fmoles/μg DNA in normal and 58–468 fmoles/mg protein and 2.5–49.5 fmoles/mg protein, in the tumour tissues; only one tumour had undetectable activity. …”
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