Retrovirus Entry by Endocytosis and Cathepsin Proteases by Yoshinao Kubo, Hideki Hayashi, Toshifumi Matsuyama, Hironori Sato, Naoki Yamamoto

“…Ecotropic murine leukemia virus entry requires cathepsin proteases activated by the endosome acidification. …”
Get full text

Production of subtilisin proteases in bacteria and yeast by A. S. Rozanov, S. V. Shekhovtsov, N. V. Bogacheva, E. G. Pershina, A. V. Ryapolova, D. S. Bytyak, S. E. Peltek

Subjects: Get full text

Some Investigations on Protease Enzyme Production Kinetics Using Bacillus licheniformis BBRC 100053 and Effects of Inhibitors on Protease Activity by Zahra Ghobadi Nejad, Soheila Yaghmaei, Nazanin Moghadam, Bahareh Sadeghein

“…Due to great commercial application of protease, it is necessary to study kinetic characterization of this enzyme in order to improve design of enzymatic reactors. …”
Get full text

Structure-Function of Falcipains: Malarial Cysteine Proteases by Kailash C. Pandey, Rajnikant Dixit

“…Studies with cysteine protease inhibitors and manipulating cysteine proteases genes have suggested a role for cysteine proteases in hemoglobin hydrolysis. …”
Get full text

Pancreas Proapoptotic Proteases in Patients with Chronic Pancreatitis by N. B. Gubegritz, E. A. Krylova, Yu. A. Gaidar

“…To study features of localization of the DNA-ase I and endonuclease-G proapoptotic proteases in the pancreas in chronic pancreatitis (CP). …”
Get full text

Expression and Characterization of Coprothermobacter proteolyticus Alkaline Serine Protease by Tanveer Majeed, Romana Tabassum, William J. Orts, Charles C. Lee

“…A putative protease gene (aprE) from the thermophilic bacterium Coprothermobacter proteolyticus was cloned and expressed in Bacillus subtilis. …”
Get full text

Evaluation of COVID-19 protease and HIV inhibitors interactions by Tran Linh, Tam Dao Ngoc Hien, Elhadad Heba, Hien Nguyen Minh, Huy Nguyen Tien

Subjects: Get full text

Protease-activated receptor 1 in the pathogenesis of cystic fibrosis by Sarath Ranganathan, Philip Sutton, Sophie Day, Poshmaal Dhar, Kristy Azzopardi, Muhammad A Saeed, Sohinee Sarkar, Jia-Xi Han

“…Background The most common cause of death in those with cystic fibrosis (CF) is respiratory failure due to bronchiectasis resulting from repeated cycles of respiratory infection and inflammation. Protease-activated receptor 1 (PAR1) is a cell surface receptor activated by serine proteases including neutrophil elastase, which is recognised as a potent modulator of inflammation. …”
Get full text

The Role of Serine Proteases and Antiproteases in the Cystic Fibrosis Lung by Matthew S. Twigg, Simon Brockbank, Philip Lowry, S. Peter FitzGerald, Clifford Taggart, Sinéad Weldon

“…Sputum from CF patients contains elevated levels of neutrophils and subsequently elevated levels of neutrophil serine proteases. In a healthy individual these proteases aid in the phagocytic process by degrading microbial peptides and are kept in homeostatic balance by cognate antiproteases. …”
Get full text

Endothelial protease-activated receptor 4: impotent or important? by Rahul Rajala, Rahul Rajala, Rahul Rajala, Courtney T. Griffin, Courtney T. Griffin

Subjects: Get full text

Glioblastoma drives protease-independent extracellular matrix invasion of microglia by Chia-Wen Chang, Ashwin Bale, Rohit Bhargava, Brendan A.C. Harley

Get full text

A multiplex method for rapidly identifying viral protease inhibitors by Seo Jung Hong, Samuel J Resnick, Sho Iketani, Ji Won Cha, Benjamin Alexander Albert, Christopher T Fazekas, Ching-Wen Chang, Hengrui Liu, Shlomi Dagan, Michael R Abagyan, Pavla Fajtová, Bruce Culbertson, Brooklyn Brace, Eswar R Reddem, Farhad Forouhar, J Fraser Glickman, James M Balkovec, Brent R Stockwell, Lawrence Shapiro, Anthony J O’Donoghue, Yosef Sabo, Joel S Freundlich, David D Ho, Alejandro Chavez

“…To speed the rate of discovery and better prepare against future threats, we establish a high-throughput platform capable of screening compounds against 40 diverse viral proteases simultaneously. This multiplex approach is enabled by using cellular biosensors of viral protease activity combined with DNA-barcoding technology, as well as several design innovations that increase assay sensitivity and correct for plate-to-plate variation. …”
Get full text

The Role of Microbial Aspartic Protease Enzyme in Food and Beverage Industries by Jermen Mamo, Fassil Assefa

“…Proteases represent one of the three largest groups of industrial enzymes and account for about 60% of the total global enzymes sale. …”
Get full text

Zymography of proteases in honey bees (Apis Mellifera) infected with Nosema ceranae by Doghuzlu Mohammad Afrasiabi, Nabian Sedigheh, Paghaleh Gholam Ali Nehzati, Taheri Mohammad, Asadollahi Zahra, Akhzari Soheila

Subjects: Get full text

Efficacy and safety of new protease inhibitor faldaprevir in treatment of hepatitis C by M. V. Mayevskaya, M. S. Zharkova, V. T. Ivashkin

Subjects: Get full text

Progress on the Classification, Characteristics and Food Industry Application of Microbial Proteases and Lipases by Yao ZHANG, Jiaxin WANG, Chanchan WEN, Jiayun HU, Xiaofeng LIU, Yuanfeng WU

Subjects: “…microbial proteases…”
Get full text

Pretreatment with serine protease inhibitors impairs Leishmania amazonensis survival on macrophages by Patrícia de Almeida Machado, Pollyanna Stephanie Gomes, Elaine Soares Coimbra, Herbert Leonel de Matos Guedes

Subjects: “…Serine proteases…”
Get full text

Secretory leukocyte protease inhibitor in punch biopsies from human colonic mucosa by Max Nyström, Ulla Peterson Westin, Carina Linder, Kjell Ohlsson

“…Secretory leukocyte protease inhibitor (SLPI) is a wellknown protease inhibitor. …”
Get full text

Chemical tools to define and manipulate interferon-inducible Ubl protease USP18 by Griffin J. Davis, Anthony O. Omole, Yejin Jung, Wioletta Rut, Ronald Holewinski, Kiall F. Suazo, Hong-Rae Kim, Mo Yang, Thorkell Andresson, Marcin Drag, Euna Yoo

“…Abstract Ubiquitin-specific protease 18 (USP18) is a multifunctional cysteine protease primarily responsible for deconjugating the interferon-inducible ubiquitin-like modifier ISG15 from protein substrates. …”
Get full text

Potato protease inhibitors, a functional food material with antioxidant and anticancer potential by Yaotong Liu, Yuanyuan Bian, Yan Bai, Siqi Yu, Yuxuan Tian, Jie Li, Suhong Li, Tuoping Li

Subjects: “…Potato protease inhibitors…”
Get full text