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SUPPRESSION OF SUBGENOMIC HEPATITIS C VIRUS RNA REPLICON REPLICATION IN Huh-7 CELLS BY THE NS3 PROTEASE INHIBITOR SCH5030334: A STOCHASTIC MATHEMATICAL MODEL
Published 2014-12-01“…Astochastic mathematical model for subgenomic HCVreplicon replication in Huh-7 cells with the presence ofthe HCVNS3 protease inhibitor SCH 503034 is proposed. The model describes the experimental kinetic curves ofviral RNAsuppression at various SCH 503034 concentrations. …”
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142
Evaluation of Melongosides as Potential Inhibitors of NS2B-NS3 Activator-Protease of Dengue Virus (Serotype 2) by Using Molecular Docking and Dynamics Simulation Approach
Published 2022-01-01“…All the melongosides interacted with the NS3 protease part of NS2B-NS3. Melongosides B, F, and N showed interactions with His51, while melongoside G interacted with Asp75 of NS3, to be noted, these are important amino acid residues in the catalytic site of the NS3 protease. …”
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143
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Effects of Different Modification Methods on the Functional Properties and Structure of Chlorella Protein
Published 2025-01-01Subjects: Get full text
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145
Two ways to one goal: new strategy of antiviral therapy for chronic hepatitis C
Published 2012-11-01Subjects: Get full text
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146
Monitoring of enzymatic cleavage reaction of GST-fusion protein on biolayer interferometry sensor
Published 2024-10-01Subjects: Get full text
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147
Medicinal plants with anti-SARS-CoV activity repurposing for treatment of COVID-19 infection: A systematic review and meta-analysis
Published 2022-06-01Subjects: “…covid-19 main protease…”
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148
Evaluation of pancreatin stability through enzyme activity determination
Published 2016-09-01Subjects: Get full text
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Enhanced Expression and Bioactivity Assessment of Recombinant SUMO-Protease-1 in E. coli BL21 (DE3) via Cleavage of His6-SMT3-SDF-1 Fusion Protein
Published 2024-01-01“…The SUMO fusion system is advantageous in improving the solubility and correct folding of proteins that are difficult to produce. SUMO-protease-1 (Ulp1) is a key enzyme in this system, and its proper expression and purification in Escherichia coli BL21 (DE3) are critical to its efficiency. …”
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151
Optimization and characterization studies of poultry waste valorization for peptone production using a newly Egyptian Bacillus subtilis strain
Published 2025-01-01Subjects: Get full text
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152
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In Silico Identification of New Anti-SARS-CoV-2 Main Protease (Mpro) Molecules with Pharmacokinetic Properties from Natural Sources Using Molecular Dynamics (MD) Simulations and Hierarchical Virtual Screening
Published 2022-01-01“…This candidate drug was used to perform MD simulations, and the outcomes revealed that ZINC000072307130 formed a stable complex with the viral main protease. Consequently, ZINC000072307130 emerges as a potential anti-SARS-CoV-2 Mpro inhibitor for the production of new COVID 19 drugs.…”
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154
Imaging flow cytometry reveals the mechanism of equine arteritis virus entry and internalization
Published 2025-01-01Subjects: Get full text
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155
Research on the quality deterioration of UHT milk products during shelf life: core microorganisms and related characteristics
Published 2024-09-01Subjects: Get full text
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156
<i>Staphylococcus aureus</i> Proteins Implicated in the Reduced Virulence of <i>sarA</i> and <i>sarA/agr</i> Mutants in Osteomyelitis
Published 2025-01-01Subjects: Get full text
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157
Interferon-free therapy of chronic hepatitis C: replacement of medications or new treatment paradigm?
Published 2014-10-01Subjects: Get full text
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158
Lopinavir and Ritonavir have High Affinity Toward the SARS-CoV-2 S-protein Receptor-binding Domain Sequenced in Brazil
Published 2025-01-01Subjects: Get full text
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Hydrolysis of fish waste using fruit wastes of Ananas comosus and Carica papaya for the formulation of liquid fertilizers
Published 2021-06-01Subjects: Get full text
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