Interferon-free therapy of chronic hepatitis C: replacement of medications or new treatment paradigm? by S. N. Batskikh

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In silico binding role of flavonoids as SARS-CoV-2 main protease (Mpro) inhibitors: A dataset of molecular docking simulation-based high-throughput virtual screening (HTVS)Mendeley Data by Mariyam Eema, Vasudeva Rao Avupati

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In Silico Identification of New Anti-SARS-CoV-2 Main Protease (Mpro) Molecules with Pharmacokinetic Properties from Natural Sources Using Molecular Dynamics (MD) Simulations and Hierarchical Virtual Screening by Harrison Onyango, Patrick Odhiambo, David Angwenyi, Patrick Okoth

“…This candidate drug was used to perform MD simulations, and the outcomes revealed that ZINC000072307130 formed a stable complex with the viral main protease. Consequently, ZINC000072307130 emerges as a potential anti-SARS-CoV-2 Mpro inhibitor for the production of new COVID 19 drugs.…”
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Lopinavir and Ritonavir have High Affinity Toward the SARS-CoV-2 S-protein Receptor-binding Domain Sequenced in Brazil by Aline Diogo Marinho, Helyson Lucas Bezerra Braz, João Alison de Moraes Silveira, Danilo Galvão Rocha, Roberta Jeane Bezerra Jorge, Geanne Matos de Andrade

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Correction: Awahara et al. The Effects of Side-Chain Configurations of a Retro–Inverso-Type Inhibitor on the Human T-Cell Leukemia Virus (HTLV)-1 Protease. <i>Molecules</i> 2022, <i>27</i>, 1646 by Chiyuki Awahara, Daiki Oku, Saki Furuta, Kazuya Kobayashi, Kenta Teruya, Kenichi Akaji, Yasunao Hattori

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First insight into temporal variation of digestive enzyme activities in flathead grey mullet (Mugil cephalus) during the ongrowing phase by Silvia Natale, Andrea Bertini, Enric Gisbert, Karl B. Andree, Elisa Benini, Dario Vallainc, Pier Paolo Gatta, Alessio Bonaldo, Luca Parma

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Triple antiviral therapy in patient with liver cirrhosis: complications and options of pharmacological treatment by M. V. Mayevskaya, I. N. Tikhonov, V. T. Ivashkin

Subjects: “…protease inhibitors…”
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Research Progress on the Structure and Function, Immune Escape Mechanism, Antiviral Drug Development Methods, and Clinical Use of SARS-CoV-2 M^pro by Jiayi Ren, Zhengfu Zhang, Yi Xia, Daqun Zhao, Dingqin Li, Shujun Zhang

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Telaprevir: options of application in separate patient groups by M. V. Mayevskaya, I. N. Tikhonov, V. T. Ivashkin

Subjects: “…protease inhibitors…”
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Antiviral activity of natural compounds extracted from Mediterranean medicinal plants against SARS-CoV-2 by Stephanie Ghio, Jean-Pierre Brincat, Yuksel Cetin, Frederick Lia

“…Host-directed therapies include the inhibition of angiotensin-converting enzyme 2 (ACE2) and transmembrane protease serine 2 (TMPRSS2). Virus-directed therapies include inhibition of papain-like protease (PLpro) and the main protease, 3-chymotrypsin-like protease (3CLpro). …”
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Halophilic Bacteria of Lunsu Produce an Array of Industrially Important Enzymes with Salt Tolerant Activity by Sonika Gupta, Parul Sharma, Kamal Dev, Anuradha Sourirajan

“…The halophilic bacterial isolates SS1, SS2, SS3, SS5, and SS8 were characterized for production of industrially important enzymes like amylase, protease, lipase, and glutaminase. Halophilic bacterial isolates SS1 and SS3 exhibited salt dependent extracellular amylase and protease activities. …”
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Respiratory Failure Associated with the Lipodystrophy Syndrome in an HIV-Positive Patient with Compromised Lung Function by Natasha Press, Valentina Montessori, Tony R Bai, Julio Montaner

“…Protease inhibitors, used as treatment in human immunodeficiency virus (HIV) infection, are associated with a syndrome of peripheral lipodystrophy, central adiposity, hyperlipidemia and insulin resistance. …”
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Direct-Acting Antivirals for the Treatment of Chronic Hepatitis C: Open Issues and Future Perspectives by Hee Bok Chae, Seon Mee Park, Sei Jin Youn

“…They are second-wave protease inhibitors, second-generation protease inhibitors, and polymerase inhibitors. …”
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PERKEMBANGAN ENZIM PENCERNAAN LARVA IKAN PATIN, Pangasius hypophthalmus sp. by Irzal Effendi, . Widanarni, D. Augustine

“…Development of digestive enzymes; protease, lipase and amylase were observed in patin catfish, Pangasius hypophthalmus, larvae.  …”
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Nelfinavir Impairs Glycosylation of Herpes Simplex Virus 1 Envelope Proteins and Blocks Virus Maturation by Soren Gantt, Eliora Gachelet, Jacquelyn Carlsson, Serge Barcy, Corey Casper, Michael Lagunoff

“…Nelfinavir (NFV) is an HIV-1 aspartyl protease inhibitor that has numerous effects on human cells, which impart attractive antitumor properties. …”
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The impact of chronic intermittent hypoxia on enzymatic activity in memory-associated brain regions of male and female rats by Steve Mabry, Jessica L. Bradshaw, Jennifer J. Gardner, E. Nicole Wilson, Janak Sunuwar, Hannah Yeung, Sharad Shrestha, J. Thomas Cunningham, Rebecca L. Cunningham

“…There is evidence that alterations in protease activity and neuronal activation are associated with cognitive dysfunction, are dependent on sex, and may be brain region-specific. …”
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Combination of Tubifex and artificial diet for catfish Pangasianodon hypophthalmus larvae by Dedi Jusadi, Ria Septy Anggraini, Muhammad Agus Suprayudi

“…Kata kunci: pakan buatan, aktivitas lipase, aktivitas protease, cacing sutra, Pangasianodon hypophthalmus …”
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Extraction of Antioxidant Peptides and Activity Evaluation of Frog (Rana nigromaculata) Skin by Ultra-high Pressure Assisted Enzyme Hydrolysis by Xicai ZHANG, Rong LI, Yechuan HUANG

“…Ultrafiltration was used to separate the protease hydrolysis solution of the skin of the frog (Rana nigromaculata) to obtain small molecule peptides with different molecular weight. …”
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Predictive Assessment of the Antiviral Properties of Imperata cylindrica against SARS-CoV-2 by Frank Eric Tatsing Foka, Hazel Tumelo Mufhandu

“…Specifically, the objective of this study was to identify I. cylindrica phytochemicals that display inhibitory effects against SARS-CoV-2 main protease (Mpro), a highly conserved protein among coronaviruses. …”
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Biochemical and Molecular Analysis of Staphylococcus aureus Clinical Isolates from Hospitalized Patients by Amit Karmakar, Parimal Dua, Chandradipa Ghosh

“…Screened isolates were further analyzed by several microbiological diagnostics tests including gelatin hydrolysis, protease, and lipase tests. It was found that 78%, 81%, and 51% isolates were positive for gelatin hydrolysis, protease, and lipase activities, respectively. …”
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