Significant Contribution of Mouse Mast Cell Protease 4 in Early Phases of Experimental Autoimmune Encephalomyelitis by Louisane Desbiens, Catherine Lapointe, Marjan Gharagozloo, Shaimaa Mahmoud, Gunnar Pejler, Denis Gris, Pedro D’Orléans-Juste

“…Mast cells are suggested to be involved in the main inflammatory phases occurring during EAE development, possibly by secreting several autacoids and proteases. Among the latter, the chymase mouse mast cell protease 4 (mMCP-4) can contribute to the inflammatory response by producing endothelin-1 (ET-1). …”
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Radical Scavenging, Proteases Activities, and Phenolics Composition of Bark Extracts from 21 Medicinal Plants by Muhammad Asam Raza, Durre Shahwar, Tania Khan

“…All extracts showed remarkable antioxidant activity (87 to 96%) while moderate activity was exhibited against protease (22 to 56%). Gallic acid, tannic acid, quercetin, rutin, catechin, hesperidin, and cinnamic acid were identified as the major phenolic acids in the extracts of selected medicinal plants.…”
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Functional mass spectrometry indicates anti-protease and complement activity increase with COVID-19 severity by Douglas D. Fraser, Douglas D. Fraser, Swapan Roy, Matt Kuruc, Maritza Quintero, Logan R. Van Nynatten, Gediminas Cepinskas, Gediminas Cepinskas, Haiyan Zheng, Amenah Soherwardy, Devjit Roy

“…Our data suggests that COVID-19 is associated with both a protease storm and complement activation, with the former somewhat balanced with increased anti-protease activity. …”
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Optimization of Protease and Amylase Production by Rhizopus oryzae Cultivated on Bread Waste Using Solid-State Fermentation by Olfa Benabda, Sana M’hir, Mariam Kasmi, Wissem Mnif, Moktar Hamdi

“…This research was carried for the coproduction of two industrial enzymes: α-amylase and protease via SSF by Rhizopus oryzae on humidified bread waste. …”
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Optimization Conditions of Extracellular Proteases Production from a Newly Isolated Streptomyces Pseudogrisiolus NRC-15 by El-Sayed E. Mostafa, Moataza M. Saad, Hassan M. Awad, Mohsen H. Selim, Helmy M. Hassan

“…Microbial protease represents the most important industrial enzymes, which have an active role in biotechnological processes. …”
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Constitutive Expression of Functionally Active Protease-Activated Receptors 1 and 2 in Human Conjunctival Epithelial Cells by Timothy J. Nickel, Mohammad H. Kabir, Jaya Talreja, Daniel J. Stechschulte, Kottarappat N. Dileepan

“…Protease-activated receptors (PARs) are G-protein-coupled receptors which initiate inflammatory responses when activated by specific serine proteases. …”
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The Effect of Serine Protease Inhibitors on Airway Inflammation in a Chronic Allergen-Induced Asthma Mouse Model by Chih-Che Lin, Li-Jen Lin, Shulhn-Der Wang, Chung-Jen Chiang, Yun-Peng Chao, Joseph Lin, Shung-Te Kao

“…Serine protease inhibitors reportedly attenuated airway inflammation and had antioxidant in multiorgan. …”
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Protease shaving of Mycobacterium tuberculosis facilitates vaccine antigen discovery and delivery of novel cargoes to the Mtb surface by Bianca A. Lepe, Christine R. Zheng, Owen K. Leddy, Benjamin L. Allsup, Sydney L. Solomon, Bryan D. Bryson

“…Here, we sought to expand our understanding of the Mtb surface proteome in service of these knowledge gaps by adapting protease shaving protocols for multiplexed quantitative mass spectrometry. …”
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Exploring covalent inhibitors of SARS-CoV-2 main protease: from peptidomimetics to novel scaffolds by Noor Atatreh, Radwa E. Mahgoub, Mohammad A. Ghattas

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Alpha-1 Antitrypsin as a Regulatory Protease Inhibitor Modulating Inflammation and Shaping the Tumor Microenvironment in Cancer by Siyu Xiang, Liu Yang, Yun He, Feng Ding, Shuangying Qiao, Zonghua Su, Zheng Chen, Aiping Lu, Fangfei Li

“…Alpha-1 antitrypsin (AAT) is a key serine protease inhibitor for regulating proteases such as neutrophil elastase. …”
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Systematic functional analysis and potential application of a serine protease from cold-adapted Planococcus bacterium by Weijun Leng, Xiaoyun Wu, Xianghui Qi, Hongying Liu, Li Yuan, Ruichang Gao

Subjects: “…Protease…”
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Effects of Pregnancy and Bacterial Vaginosis on Proinflammatory Cytokine and Secretory Leukocyte Protease Inhibitor Concentrations in Vaginal Secretions by Jennifer Balkus, Kathy Agnew, Richard Lawler, Caroline Mitchell, Jane Hitti

“…We compared vaginal proinflammatory cytokine and secretory leukocyte protease inhibitor (SLPI) concentrations among pregnant and nonpregnant women according to bacterial vaginosis (BV) status. …”
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Stage-specific expression and divergent functions of two insulinase-like proteases associated with host infectivity in Cryptosporidium. by Yue Huang, Shifeng Pei, Xin Lv, Fuxian Yang, Xiaoqing Gong, Na Li, Yaqiong Guo, Yaoyu Feng, Lihua Xiao

“…Results from recent comparative genomic studies suggest that gains and losses of multicopy subtelomeric genes encoding insulinase-like proteases (INS-19 and INS-20 in Cryptosporidium parvum and their orthologs in closely related species) may potentially contribute to these differences.…”
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Transferability of bioprocessing modes for recombinant protease production: from fed-batch to continuous cultivation with Bacillus licheniformis by Stefan Kittler, Fabian Müller, Mohamed Elshazly, Georg Benjamin Wandrey, Tobias Klein, Andreas Daub, Oliver Spadiut, Julian Kopp

“…Abstract Background Proteases are essential in various industries due to their unique substrate specificities and robustness in different operational conditions. …”
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Promising inhibitors against main protease of SARS CoV-2 from medicinal plants: In silico identification by EBENEZER OLUWAKEMI, SHAPI MICHAEL

Subjects: “…sars cov-2 main protease inhibitors…”
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Responses of α-amylase and protease activity to chemical agents and metallic salts in barley seeds (Hordeum vulgare L.) by Amin Hossain, Umma Fatema Shahjadee, Abu Tareq Mohammad Abdullah, Mohammad Nazrul Islam Bhuiyan, Anjum Zerin Rupa

“…To determine the impact of each chemical on the stability of α-amylase and protease enzyme activity using standard assay procedures. …”
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Optimization of Acid Protease Production by Aspergillus niger I1 on Shrimp Peptone Using Statistical Experimental Design by Rayda Siala, Fakher Frikha, Samiha Mhamdi, Moncef Nasri, Alya Sellami Kamoun

“…Medium composition and culture conditions for the acid protease production by Aspergillus niger I1 were optimized by response surface methodology (RSM). …”
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Profiling Pro‐Inflammatory Proteases as Biomolecular Signatures of Material‐Induced Subcutaneous Host Response in Immuno‐Competent Mice by Nam M.P. Tran, Anh T.H. Truong, Dang T. Nguyen, Tram T. Dang

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Protease-activated receptors in vascular smooth muscle cells: a bridge between thrombo-inflammation and vascular remodelling by Anxhela Habibi, Wolfram Ruf, Leon Schurgers

Subjects: “…Protease-activated receptors…”
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Comparative Effectiveness of Darunavir 1,200 mg Daily and Approved Dosing Strategies for Protease Inhibitor-Experienced Patients by James M. Mikula, Chiu-Bin Hsiao, Joshua R. Sawyer, Qing Ma, Gene D. Morse

“…Background. HIV protease inhibitors exhibit concentration-dependent viral inhibition. …”
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