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Efficacy and safety of new protease inhibitor faldaprevir in treatment of hepatitis C
Published 2013-12-01Subjects: Get full text
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Etoposide targets 2A protease to inhibit enterovirus 71 replication
Published 2025-01-01“…Notably, no clinically approved drugs specifically target EV71. The EV71 2A protease (2Apro), a cysteine protease produced by the virus, is essential for the virus’ replication and has a significant impact on the functioning of host cells. …”
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Progress on the Classification, Characteristics and Food Industry Application of Microbial Proteases and Lipases
Published 2025-02-01Subjects: “…microbial proteases…”
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24
Mechanistic studies on regulation of the activity of GPI-anchored serine protease testisin
Published 2024-12-01Subjects: Get full text
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25
Pretreatment with serine protease inhibitors impairs Leishmania amazonensis survival on macrophages
Published 2025-01-01Subjects: “…Serine proteases…”
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Secretory leukocyte protease inhibitor in punch biopsies from human colonic mucosa
Published 2001-01-01“…Secretory leukocyte protease inhibitor (SLPI) is a wellknown protease inhibitor. …”
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27
Chemical tools to define and manipulate interferon-inducible Ubl protease USP18
Published 2025-01-01“…Abstract Ubiquitin-specific protease 18 (USP18) is a multifunctional cysteine protease primarily responsible for deconjugating the interferon-inducible ubiquitin-like modifier ISG15 from protein substrates. …”
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Potato protease inhibitors, a functional food material with antioxidant and anticancer potential
Published 2023-09-01Subjects: “…Potato protease inhibitors…”
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29
Cellulase, xylanase, lipase, and protease activities of selected wild mushrooms from Slovenia
Published 2025-01-01“…In this work, the cellulase, xylanase, protease, and lipase activities were measured in aqueous extracts of 64 Slovenian wild mushrooms of different lifestyles (symbiotic, saprobic, parasitic). …”
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Inhibition of Tannerpin-M encoded by periodontal pathogens on serine proteases released by granulocytes
Published 2024-12-01Subjects: “…serine protease inhibitor…”
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31
Structural Analysis of Inhibitor Binding to Enterovirus-D68 3C Protease
Published 2025-01-01Subjects: Get full text
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32
Nutritional evaluation of inactivated whole soy and protease enzyme for growing and finishing pigs
Published 2025-01-01“…ABSTRACT The inactivated whole soy (IWS) was studied in pigs to determine the energy value through a metabolism trial and evaluate the effect of IWS and protease on performance, carcass traits, and economic viability. …”
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Production of Secretory Leucocyte Protease Inhibitor (SLPI) in Human Pancreatic β-Cells
Published 1999-01-01“…Secretory leucocyte protease inhibitor (SLPI) is a potent inhibitor of granulocyte elastase and cathepsin G, and also an inhibitor of pancreatic enzymes like trypsin, chymotrypsin and pancreatic elastase. …”
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The Activity of Metalloproteases and Serine Proteases in Various Organs after Leiurus macroctenus Envenomation
Published 2023-01-01“…The present study aimed to examine the total proteolysis levels in various organs after Leiurus macroctenus envenomation and evaluate the metalloproteases and serine proteases’ contributions to the total proteolytic activity. …”
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LPS Counter Regulates RNA Expression of Extracellular Proteases and Their Inhibitors in Murine Macrophages
Published 2012-01-01“…This process is accomplished by multiple proteolytic enzymes, including serine proteases and members of the matrix metalloproteinase family. …”
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Streptomyces lavendulae Protease Inhibitor: Purification, Gene Overexpression, and 3-Dimensional Structure
Published 2015-01-01“…SDS-PAGE of protease inhibitor showed molecular weight of approximately 10 KDa. …”
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Thrombin-Induced Calpain Activation Promotes Protease-Activated Receptor 1 Internalization
Published 2017-01-01“…The serine protease thrombin activates Protease-Activated Receptors (PARs), a family of G-protein-coupled receptors (GPCRs) activated by the proteolytic cleavage of their extracellular N-terminal domain. …”
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Serine Proteases of Malaria Parasite Plasmodium falciparum: Potential as Antimalarial Drug Targets
Published 2014-01-01“…Proteases belonging to various mechanistic classes are found in P. falciparum, of which serine proteases are of particular interest due to their involvement in parasite-specific processes of egress and invasion. …”
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Secretory Leukocyte Protease Inhibitor Is an Inducible Antimicrobial Peptide Expressed in Staphylococcus aureus Endophthalmitis
Published 2007-01-01“…To describe the presence of secretory leukocyte protease inhibitor (SLPI), a cationic peptide with antimicrobial and antiprotease activity, in the innate ocular immune reaction in a rat model of Staphylococcus aureus endophthalmitis. …”
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A bacterial type III effector hijacks plant ubiquitin proteases to evade degradation.
Published 2025-01-01“…Moreover, RipE1 associates with plant ubiquitin proteases, which contribute to RipE1 deubiquitination and stabilization. …”
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