Differential responses of Bradyrhizobium sp. SUTN9-2 to plant extracts and implications for endophytic interactions within different host plants by Teerana Greetatorn, Pakpoom Boonchuen, Pongdet Piromyou, Pongpan Songwattana, Jenjira Wongdee, Kamonluck Teamtisong, Nantakorn Boonkerd, Shusei Sato, Neung Teaumroong, Panlada Tittabutr

“…This study suggests that SUTN9-2 likely evolves resistance mechanisms against CAMPs found in rice, chili, and tomato plants through mechanisms involving the protease-chaperone DegP, AcrAB-TolC multidrug efflux pumps, and polysaccharides. …”
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The Role of Yersinia enterocolitica O:3 Lipopolysaccharide in Collagen-Induced Arthritis by Katarzyna Kasperkiewicz, Anna S. Świerzko, Marta Przybyła, Janusz Szemraj, Jarosław Barski, Mikael Skurnik, Andrzej Kałużyński, Maciej Cedzyński

“…In addition, the Rd1 LPS activates the MBL-associated serine protease 1 (MASP-1) stronger than the S and Ra chemotype LPS and comparable to Klebsiella pneumoniae O:3 LPS. …”
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Bacteria-Inspired Synthesis of Silver-Doped Zinc Oxide Nanocomposites: A Novel Synergistic Approach in Controlling Biofilm and Quorum-Sensing-Regulated Virulence Factors in <i>Pseu... by Abirami Karthikeyan, Manoj Kumar Thirugnanasambantham, Fazlurrahman Khan, Arun Kumar Mani

“…Additionally, biofilm formation (81.1%) and EPS production (83.9%) using <i>P. aeruginosa</i> were substantially hindered, along with reduced extracellular protease activity, as indicated by zone formation (from 2.3 to 1.8 cm). …”
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Maternal obesity exacerbates the responsiveness of offspring BALB/c mice to cow’s milk protein-induced food allergy by Jingxin Gao, Tiange Li, Dong Liang, Han Gong, Liang Zhao, Xueying Mao

“…Maternal obesity increased the serum immunoglobulin E and mouse mast cell protease levels, though did not have significant influence on anaphylactic symptom score, core temperature and diarrhea rate of offspring mice after BLG sensitization. …”
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Evaluation of the binding affinity and antioxidant activity of phlorizin to pepsin and trypsin by Jing Zhang, Di Wu, Lan Tang, Xia Hu, Zhen Zeng, Wen Wu, Fang Geng, Hui Li

“…The ground state complexes PHL and protease have a moderate affinity of 105 L/mol PHL binds more strongly to trypsin than to pepsin. …”
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Research progress of protein haze in white wines by Zhaolong Liu, Le Xu, Jun Wang, Changqing Duan, Yanfeng Sun, Qingsen Kong, Fei He

“…Unstable wine proteins were usually pathogenesis-related (PR) proteins of grapes, mainly chitinases and thaumatin-like proteins (TLPs), which had lower isoelectric point (pI) and smaller molecular weight, and were highly resistant to the low pH values of wines and the protease hydrolysis during fermentation. At present, the technology of protein stabilization and clarification in white wines mainly included bentonite fining, heat treatment, enzymatic hydrolysis, polysaccharide treatment and ultrafiltration methods. …”
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Preparation of Xanthine Oxidase Inhibitory Peptide from Black Bean Protein by Enzymatic Hydrolysis and Its Uric Acid-Lowering Activity in Vitro by SUN Jingru, SUN Mingshuang, LÜ Wenqing, CAO Rong’an, DIAO Jingjing, WANG Changyuan

“…Based on XOD inhibitory activity and degree of hydrolysis (DH), various proteases were screened, and the hydrolysis parameters were optimized. …”
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Evaluation of the effect of 48 weeks of BIC/F/TAF and DRV/c/F/TAF on platelet function in the context of rapid ART start by Akif A. Khawaja, Gary Whitlock, Sarah Fidler, Alfredo Soler-Carracedo, Merle Henderson, Graham P. Taylor, Marta Boffito, Michael Emerson

“…Despite differences in the demographics between treatment arms, the presence of an unboosted integrase inhibitor or boosted protease inhibitor in a test-and-treat setting did not impact platelet function. …”
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PAI-1: An Integrator of Cell Signaling and Migration by Ralf-Peter Czekay, Cynthia E. Wilkins-Port, Stephen P. Higgins, Jennifer Freytag, Jessica M. Overstreet, R. Matthew Klein, Craig E. Higgins, Rohan Samarakoon, Paul J. Higgins

“…It is now apparent that several proteases and protease inhibitors, most notably urokinase plasminogen activator (uPA) and plasminogen activator inhibitor type-1 (PAI-1), also interact with several cell surface receptors transducing intracellular signals that significantly affect both motile and proliferative programs. …”
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Mechanistic studies on the effect of endogenous proteins on the starch retrogradation characteristics of corn before and after postharvest ripening by Nannan Hu, Weihua Qi, Jinying Zhu, Fuyin Zhao, Lin Xiu, Mingzhu Zheng, Jingsheng Liu

“…The corn starch-protein complexes before postharvest ripening (JD-0) and after postharvest ripening (JD-40) were subjected to protease treatment, and the influence of protein on starch retrogradation was studied. …”
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Quantifying LAGA mutated mouse IgG2a monoclonal antibody with a rapid pepsin digestion enabled immunoaffinity LC/MS/MS assay by Linlin Dong, Susan Chen, Konstantin Piatkov, Dong Wei, Mark G. Qian

“…To overcome these challenges, a trypsin alternative pepsin, an aspartic protease, was systematically investigated for its use in digesting the mutated mIgG2a antibody to allow generation of signature peptides for the bioanalytical quantification purpose. …”
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Taxonomic and ecophysiological characteristics of actinobacteria in soils of the dry steppe zone of the Selenga Highlands (Western Transbaikalia) by E. P. Nikitina, L. B. Buyantueva, E. Yu. Abidueva, C. H. Sun

“…The examinations of extracellular enzymes showed that all isolates were capable of producing catalase and amylase; 78.6 % of the total number of isolates produced protease and lipase; 53.6 %, cellulase; and 28.6 %, urease. …”
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Isolation and Evaluation of <i>Rhizopus arrhizus</i> Strains from Traditional Rice Wine Starters (<i>Jiuqu</i>): Enzyme Activities, Antioxidant Capacity, and Flavour Compounds by Bo Wan, Tian Tian, Ying Xiong, Siqi Wang, Xinyu Luo, Weifang Liao, Pulin Liu, Lihong Miao, Ruijie Gao

“…Significant variation in enzyme activities was observed, with acidic protease activity ranging from 280 to 1023 U/g, amylase from 557 to 1681 U/g, and esterase from 370 to 2949 U/g. …”
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Nuciferine relieves type 2 diabetes mellitus via enhancing GLUT4 expression and translocation by Tongxi Zhou, Guanjun Song, Di Tian, Qinghua Liu, Jinhua Shen, Xinzhou Yang, Ping Zhao

“…A laser scanning confocal microscope was used to track the translocation of glucose transporter 4 (GLUT4) in L6 cells and the changes in intracellular Ca2+ levels in real time, and related protease inhibitors combined with western blotting were used to explore the mechanism of nuciferine. …”
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Classification of Nanomaterial Drug Delivery Systems for Inflammatory Bowel Disease by Wang H, Zhou F, Shen M, Ma R, Yu Q

“…In addition, NDDS can enable targeted delivery, increase local drug concentrations, improve efficacy, and reduce side effects, as well as protecting active drug molecules from immune recognition and protease degradation. The clinical use of these systems for treating IBD, however, requires further research. …”
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Effect of different feeding regimes in amur common carp fingerlings: compensatory growth, physio-metabolic responses, and expression of IGF-1 gene by Chowdhury Arka, Ghosh Tapas Kumar, Khatua Sanjib, Hore Sayani, Kumari Palak, Kajal Kumari, Jana Prasanta

“…T2/1 asserted superior digestive capacity in the starved group, with elevated (P < 0.05) protease and amylase activity. Reduced (P < 0.05) hepatic lactate dehydrogenase and malate dehydrogenase activity in T2/1 group suggests reduced stress, which might strengthen compensatory growth. …”
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ALDH2 Overexpression Alleviates High Glucose-Induced Cardiotoxicity by Inhibiting NLRP3 Inflammasome Activation by Ruiping Cao, Dian Fang, Jiahui Wang, Ying Yu, Hongwei Ye, Pinfang Kang, Zhenghong Li, Hongju Wang, Qin Gao

“…The results showed in high glucose condition that ALDH2 overexpression significantly increased H9C2 cardiac cell viability, increased mitochondrial ALDH2 activity and protein expression, and reduced mitochondrial reactive oxygen species (ROS) production, 4-hydroxynonenal (4-HNE), and lactate dehydrogenase (LDH) levels; meanwhile, the pyroptosis key components—NLRP3 inflammasome-related proteins, apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC), cysteine-containing aspartate specific protease 1 (Caspase-1), and interleukin-18 (IL-18) protein expressions—were significantly decreased, and IL-18 and interleukin-1β (IL-1β) levels were also decreased. …”
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Incidence of Hyperlipidemia among Adults Initiating Antiretroviral Therapy in the HIV Outpatient Study (HOPS), USA, 2007–2021 by Jun Li, Selom Agbobli-Nuwoaty, Frank J. Palella, Richard M. Novak, Ellen Tedaldi, Cynthia Mayer, Jonathan D. Mahnken, Qingjiang Hou, Kimberly Carlson, Angela M. Thompson-Paul, Marcus D. Durham, Kate Buchacz

“…Among 349 eligible ART-naïve PWH, 168 were prescribed INSTI-based ART (36 raltegravir (RAL), 51 dolutegravir (DTG), and 81 INSTI-others (elvitegravir and bictegravir)) and 181 non-INSTI-based ART, including 68 protease inhibitor (PI)-based ART. During a median follow-up of 1.4 years, hyperlipidemia rates were 12.8, 22.3, 22.7, 17.4, and 12.6 per 100 person years for RAL-, DTG-, INSTI-others-, non-INSTI-PI-, and non-INSTI-non-PI-based ART, respectively. …”
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Immunoreactivity of the SARS-CoV-2 entry proteins ACE-2 and TMPRSS-2 in murine models of hormonal manipulation, ageing, and cardiac injury by Susan Bengs, Alexia Rossi, Martina Haberecker, Nidaa Mikail, Alexander Meisel, Achi Haider, Muriel Grämer, Angela Portmann, Atanas Todorov, Christof Schönenberger, Caroline E. Gebhard, Gabriela M. Kuster, Vera Regitz-Zagrosek, Catherine Gebhard

“…Abstract Previous work indicates that SARS-CoV-2 virus entry proteins angiotensin-converting enzyme 2 (ACE-2) and the cell surface transmembrane protease serine 2 (TMPRSS-2) are regulated by sex hormones. …”
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Characterization of the First Marine Pestivirus, Phocoena Pestivirus (PhoPeV) by Lars Söder, Denise Meyer, Olaf Isken, Norbert Tautz, Matthias König, Alexander Postel, Paul Becher

“…Pestiviruses generally counteract the cellular innate immune response by degradation of interferon regulatory factor 3 (IRF3) mediated by the viral N-terminal protease (N^pro). No degradation of IRF3 and an increased expression of the type 1 interferon-stimulated antiviral protein Mx1 was observed in porcine cells infected with PhoPeV whose genome lacks the N^pro encoding region. …”
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