Changes in cancer incidence and stage during the COVID-19 pandemic in 2020–2021 in the Nordic countries by Anna Johansson, Anna Skog, Tom Børge Johannesen, Tor Åge Myklebust, Simon M. Kønig, Charlotte Wessel Skovlund, Lina Steinrud Mørch, Søren Friis, Marnar Fríðheim Kristiansen, David Pettersson, Eva María Gudmundsdóttir, Nanna Margrét Kristinsdóttir, Helgi Birgisson, Sandra Irenaeus, Johan Ahlgren, Mats Lambe, Elli Hirvonen, Janne Pitkäniemi, Giske Ursin

“…Stage I breast cancer incidence declined during 2020 in Denmark/Norway/Sweden, with some catch-up in stage II incidence in 2021. Prostate cancer rates declined in Denmark/Finland/Norway/Sweden during 2020–2021, while melanoma rates declined in Finland in 2020. …”
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Phase 1, open-label, dose-escalation study on the safety, pharmacokinetics, and preliminary efficacy of intravenous Coxsackievirus A21 (V937), with or without pembrolizumab, in pat... by Christy Ralph, Sumati Gupta, Matthew Zibelman, Brendan D Curti, Kevin J Harrington, Steven J O'Day, Andrew G Hill, David C Campbell, Gavin M Wright, David E Gerber, Jonathan E Rosenberg, Jaime R Merchan, Charles M Rudin, Hardev S Pandha, Wallace L Akerley, Daphne Day, Timothy D Clay, Ross R Jennens, Yixin Ren, Emmett V Schmidt, Lisa Guttman

“…This phase 1 study evaluated intravenous V937±pembrolizumab in patients with advanced solid tumors.Methods Patients had advanced non-small cell lung cancer (NSCLC), urothelial cancer, metastatic castration-resistant prostate cancer, or melanoma in part A (V937 monotherapy), and metastatic NSCLC or urothelial cancer in part B (V937+pembrolizumab). …”
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Identification and validation of a novel autoantibody biomarker panel for differential diagnosis of pancreatic ductal adenocarcinoma by Metoboroghene O. Mowoe, Metoboroghene O. Mowoe, Hisham Allam, Joshua Nqada, Marc Bernon, Karan Gandhi, Sean Burmeister, Urda Kotze, Miriam Kahn, Christo Kloppers, Suba Dharshanan, Zafirah Azween, Pamela Maimela, Paul Townsend, Eduard Jonas, Jonathan M. Blackburn, Jonathan M. Blackburn

“…Specifically, we quantified the serological AAb profiles of 94 PDAC, chronic pancreatitis (CP), other pancreatic- (PC) and prostate cancers (PRC), non-ulcer dyspepsia patients (DYS), and healthy controls (HC).ResultsCombinatorial ROC curve analysis on the training cohort data from the cancer antigen microarrays identified the most effective biomarker combination as CEACAM1-DPPA2-DPPA3-MAGEA4-SRC-TPBG-XAGE3 with an AUC = 85·0% (SE = 0·828, SP = 0·684). …”
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Antispermatogenic Activity of the Benzothiazoline Ligand and Corresponding Organoantimony(V) Derivative in Male Albino Rats

“…The oral administration of both <mml:math> <mml:mtext mathvariant="bold">1a</mml:mtext> </mml:math> and <mml:math> <mml:mtext mathvariant="bold">1b</mml:mtext> </mml:math> at the dose level of 10 mg/rat/day produced significant reduction in the weights of testes, epididymides, seminal vesicles, and ventral prostate. Significant decrease in sperm motility as well as in sperm density resulted in 100% sterility. …”
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Liposomal encapsulation of cholecalciferol mitigates in vivo toxicity and delays tumor growth by Miriam Ezcurra-Hualde, Miriam Ezcurra-Hualde, Sara Zalba, Sara Zalba, Ángela Bella, Ángela Bella, Leire Arrizabalaga, Leire Arrizabalaga, Aline Risson, Aline Risson, Román García-Fuentes, Román García-Fuentes, Celia Gomar, Celia Gomar, Nuria Ardaiz, Nuria Ardaiz, Virginia Belsue, Virginia Belsue, David Ruiz-Guillamon, David Ruiz-Guillamon, Alejandro Serrano-Alcaide, Alejandro Serrano-Alcaide, Ainara Salgado, Ainara Salgado, Fernando Aranda, Fernando Aranda, Maria J. Garrido, Maria J. Garrido, Pedro Berraondo, Pedro Berraondo, Pedro Berraondo

“…In vitro gene expression modulation was evaluated in monocytic THP-1 cells, and antiproliferative effects were assessed in HT29 (colorectal), BT474 (breast), and TRAMP-C1 (prostate) cancer cell lines. In vivo antitumor efficacy and toxicity were tested in a mouse model with subcutaneously implanted MC38 tumors. …”
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Identification of new candidate genes for the hereditary predisposition to uveal melanoma: IGCMU trial by Mélanie Godiveau, Mélanie Godiveau, Mélanie Godiveau, Angeline Ginzac, Angeline Ginzac, Angeline Ginzac, Yannick Bidet, Yannick Bidet, Flora Ponelle-Chachuat, Flora Ponelle-Chachuat, Maud Privat, Maud Privat, Xavier Durando, Xavier Durando, Xavier Durando, Xavier Durando, Mathias Cavaillé, Mathias Cavaillé, Mathis Lepage, Mathis Lepage

“…Epidemiological studies have suggested an increased risk of prostate cancer, thyroid cancer, and leukemia among patients with UM, indicating potential unidentified genetic predispositions. …”
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Effect of Benzothiazoline Ligand and Corresponding Organoantimony(V) Derivative on the Reproductive System of Male Rats

“…The oral administration of compounds <mml:math> <mml:mtext mathvariant="bold">1</mml:mtext> </mml:math> and <mml:math> <mml:mtext mathvariant="bold">2</mml:mtext> </mml:math> at the dose level of 10 mg/rat/day significantly reduced the weights of testes, epididymides, ventral prostate, and seminal vesicles. The production of preleptotene spermatocytes was decreased by <mml:math> <mml:mtext>36</mml:mtext><mml:mtext>.57%</mml:mtext> </mml:math>; <mml:math> <mml:mtext>57</mml:mtext><mml:mtext>.23%</mml:mtext> </mml:math>, pachytene spermatocytes by <mml:math> <mml:mtext>40</mml:mtext><mml:mtext>.06%</mml:mtext> </mml:math>; <mml:math> <mml:mtext>62</mml:mtext><mml:mtext>.01%</mml:mtext> </mml:math>, and secondary spermatocytes by <mml:math> <mml:mtext>52</mml:mtext><mml:mtext>.45%</mml:mtext> </mml:math>; <mml:math> <mml:mtext>63</mml:mtext><mml:mtext>.22%</mml:mtext> </mml:math>, following the treatment of compounds <mml:math> <mml:mtext mathvariant="bold">1</mml:mtext> </mml:math> and <mml:math> <mml:mtext mathvariant="bold">2</mml:mtext> </mml:math>, respectively. …”
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Clinical Remission of Chronic Refractory Pelvic Symptoms in Three Men by Bradley R. Hennenfent, Antonio Espinosa Feliciano

“…In the Manila Genitourinary Clinic, the patients were treated with microbial diagnosis, antimicrobial therapy, and 19, 27, and 21 prostatic massages respectively. All three patients underwent resolution of symptoms.…”
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Synthesis and Characterization of New Amino Acid-Schiff Bases and Studies their Effects on the Activity of ACP, PAP and NPA Enzymes (In Vitro) by Zahraa Salim M. Al-Garawi, Ivan Hameed R. Tomi, Ali Hussein R. Al-Daraji

“…Their effects on the activity of total (ACP), prostatic (PAP) and non prostatic (NPA) acid phosphatase enzymes were studied. …”
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Spontaneous Intraperitoneal Rupture of Bladder Diverticulum: A Rare Cause of Peritonitis by Ahmed Ibrahimi, Adil Kallat, Idriss Ziani, Hachem El Sayegh, Lounis Benslimane, Yassine Nouini

“…Etiologies are dominated by bladder outlet obstruction, represented mainly by benign prostatic hypertrophy (BPH) in elderly men. Clinical presentation is nonspecific, leading to delayed diagnosis and treatment. …”
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Polymyalgia Rheumatica Revealing a Lymphoma: A Two-Case Report by Frank Verhoeven, Xavier Guillot, Mickaël Chouk, Clément Prati, Daniel Wendling

“…A 73-year-old man known for prostatic neoplasia in remission for 5 years presented arthromyalgia of the limb girdle since one month. …”
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Comparison between Two Different Two-Stage Transperineal Approaches to Treat Urethral Strictures or Bladder Neck Contracture Associated with Severe Urinary Incontinence that Occurr... by A. Simonato, M. Ennas, A. Benelli, A. Gregori, F. Oneto, E. Daglio, P. Traverso, G. Carmignani

“…The recurrence of urethral/bladder neck stricture after multiple endoscopic procedures is a rare complication that can follow prostatic surgery and its treatment is still controversial. …”
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Urinary Incontinence due to Overactive Detrusor Muscle: A Rare Side Effect of Venlafaxine by Vithyalakshmi Selvaraj, Palanikumar Gunasekar, Suneel Kumar, Imad Alsakaf

“…We report a case of reemergence of urinary incontinence (UI) in a patient with benign prostatic hyperplasia (BPH) after starting treatment with venlafaxine who was stabilized on tamsulosin and finasteride for about 6 years. …”
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Doctor Alfredo Méndez Aguirre. Renowned doctor of Cienfuegos medical history in the twentieth century by Reinaldo José Pino Blanco, Rigoberto Flores Roó, Alfredo Darío Espinosa Brito

“…Analyzed through different scenarios where he acted as an eminent surgeon, we refer to his contribution to the spreading of abdominal, prostatic and gynecological surgery in Cienfuegos, besides other innovations of high importance for the Cuban Medicine at that time. …”
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Reviewing the Emergence of Lactococcus garvieae: A Case of Catheter Associated Urinary Tract Infection Caused by Lactococcus garvieae and Escherichia coli Coinfection by Tatvam T. Choksi, Farhan Dadani

“…We report a rare case of catheter associated urinary tract infection (CAUTI) caused by Lactococcus garvieae and Escherichia coli coinfection without any bacteremia in a patient with indwelling urinary catheter placed for benign prostatic hyperplasia (BPH). The patient also had a history of gastroesophageal reflux disease (GERD) with long standing famotidine treatment. …”
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The Immune Response to Tumors as a Tool toward Immunotherapy by F. Pandolfi, R. Cianci, D. Pagliari, F. Casciano, C. Bagalà, A. Astone, R. Landolfi, C. Barone

“…Herein we will review some of the recent achievement of immunotherapy in such aggressive cancers as melanoma, prostatic cancer, colorectal carcinoma, and hematologic malignancies. …”
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Canadian Laboratory Standards for Sexually Transmitted Infections: Best Practice Guidelines by Max A Chernesky, David Patrick

“…Sexually transmitted or associated syndromes such as cervicitis, enteric infections, epididymitis, genital ulcers, sexually related hepatitis, ophthalmia neonatorum, pelvic inflammatory disease, prostatitis and vulvovaginitis present a challenge for the physician to identify the microbial cause, treat the patient and manage contacts. …”
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Superficial Bladder Cancer Therapy by Emmanuel Schenkman, Donald L. Lamm

“…The initial clinical stage and grade remain the main determinant factors in survival regardless of the treatment. Prostatic urethral mucosal involvement with bladder cancer can be effectively treated with Bacillus Calmette-Guerin (BCG) intravesical immunotherapy. …”
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Monitoring Detrusor Oxygenation and Hemodynamics Noninvasively during Dysfunctional Voiding by Andrew J. Macnab, Lynn S. Stothers, Babak Shadgan

“…The current literature indicates that lower urinary tract symptoms (LUTSs) related to benign prostatic hyperplasia (BPH) have a heterogeneous pathophysiology. …”
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Penetrating Posterior Urethral Injuries: Case Report and Management Strategies by Seyed Sajjad Tabei, Brandon Lippold, Wesley Baas, Gregory Murphy

“…Unlike bladder neck injuries, immediate urethroplasty/fistula repair would be very challenging and not advised for standard prostatic or membranous injuries. Urethral catheter or suprapubic tube is recommended and can result in fistula closure and urethral patency. …”
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