Propranolol in Use for Treatment of Complex Infant Hemangiomas: Literature Review Regarding Current Guidelines for Preassessment and Standards of Care before Initiation of Therapy by Andreas Fette

“…In 2008, the positive effects of propranolol on infantile hemangiomas (IH) have been discovered serendipitously by Léauté-Labrèze and her coworkers. …”
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Localized propranolol delivery from a copper-loaded hydrogel for enhancing infected burn wound healing via adrenergic β-receptor blockade by Wenzhe Sun, Hongwei Lu, Pengqin Zhang, Lian Zeng, Bing Ye, Yi Xu, Jianan Chen, Peiran Xue, Jialin Yu, Kaifang Chen, Bin Wu, Xiao Lv, Xiaodong Guo, Yanzhen Qu

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Disorders of the central nervous system cognitive and mnestic functions in genetic arterial hypertension and with the use of beta-blockers of different generations by A. O. Svitlytskyi, A. A. Yehorov, O. V. Melnikova, T. A. Hrekova

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Association of non-selective β blockers with the development of renal dysfunction in liver cirrhosis: a systematic review and meta-analysis by Xiangbo Xu, Fangbo Gao, Ting Wang, Zuyao Yang, Qingchun Zhao, Xingshun Qi

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Exendin-4 Exacerbates Burn-Induced Morbidity in Mice by Activation of the Sympathetic Nervous System by Xiao-Jing Ji, Ji-Wei Hao, Guang-Lei Li, Ning Dong, Xin-Qi Wang, Min Zhou, Qing-Hong Zhang, Yong-Ming Yao

“…Although the exacerbated burn-induced mortality by exendin-4 was worsened by propranolol pretreatment, the inhibition of T cell proliferation by exendin-4 in vitro could be restored by propranolol instead of exendin (9-39). …”
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THE EFFECT OF PROPANOLOL ON C-REACTIVE PROTEIN IN PATIENTS WITH SEVERE BURNS AT DR. SOETOMO GENERAL ACADEMIC HOSPITAL, SURABAYA, INDONESIA by Muhammad Aulia U H, Iswinarno Doso Saputro, Magda Rosalina Hutagalung

“…Highlights: • The biochemical marker of inflammation and suggests a potential mechanism through which propranolol affects hypermetabolism in burn patients…”
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β-receptor blocker enhances anti-tumor immunity via inhibiting lactate-induced norepinephrine metabolism of macrophages during malignant pleural effusion by Ru Zhang, Weijia Wang, Aitian Li, Huishang Wang, Xiaoyan Liu, Feifei Fan, Ying Wang, Huanyu Zhang, Jingxia Chang, Yinyin Zhang, Hongmin Wang, Lijun Miao, Bo Huang, Li Yang, Li Yang, Li Yang, Yi Zhang, Yi Zhang, Yi Zhang, Yi Zhang, Yi Zhang

“…Lastly, to further evaluate the effect of propranolol on MPE therapy in vivo, we developed a mouse model of MPE. …”
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Lymphatic Malformation, Retinoblastoma, or Facial Cleft: Atypical Presentations of PHACE Syndrome by María Fernández-Ibieta, Juan Carlos López-Gutiérrez

“…Two patients’ hemangiomas responded well to propranolol therapy. The first one was followed and treated in the pre-propranolol era and had a moderate response to corticoids and interferon.…”
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Efficacy and Safety of Prophylactic Agents in Prevention of Retinopathy of Prematurity: A Systematic Review and Meta-analysis of Randomised Controlled Trials by Waleed T Batais, Nada O Taher, Abeer K Alhindi, Abdullah A Ghaddaf, Anas Alamoudi, Sarah A Al-Ghamdi, Jumanah J Homsi, Hashem S Almarzouki, Mansour A Qurashi

“…The efficacy and safety of prophylactic agents, including vitamin A, propranolol and lipids, in reducing ROP incidence remain unclear. …”
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Kombinasi Injeksi Triamsinolon Asetat Intralesi dan Propanolol Oral pada Kasus Hemangioma Kapiler Palpebra by Mardijas Efendi, Hendriati Hendriati, Ardizal Rahman, Muhammad Fadhil Rahmadiansyah

“…The patient was diagnosed with capillary hemangioma and given an injection of triamcinolone acetate intralesional and oral propranolol under the supervision of a pediatrician. …”
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Drug Use Evaluation of Beta-Blockers in Medical Wards of Nedjo General Hospital, Western Ethiopia by Ginenus Fekadu, Firomsa Bekele, Kumera Bekele, Sagni Hanbisa, Gemechis Belay, Mudasir Maqbool

“…Most drugs interacting were propranolol with cimetidine 26 (68.42%), and the most frequent condition for which beta-blockers were prescribed was hypertension (32.89%). …”
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The antidepressant drug sertraline is a novel inhibitor of yeast Pah1 and human lipin 1 phosphatidic acid phosphatases by Geordan J. Stukey, Matthew R. Breuer, Natalie Burchat, Ruta Jog, Kollin Schultz, Gil-Soo Han, Matthew S. Sachs, Harini Sampath, Ronen Marmorstein, George M. Carman

“…The inhibitor constants of sertraline for the S. cerevisiae and human PAP enzymes were 7-fold and ∼2-fold, respectively, lower than those of propranolol, a commonly used PAP inhibitor. Consistent with the inhibitory mechanism of sertraline and propranolol, molecular docking of the inhibitors predicts that they interact with non-catalytic residues in the haloacid dehalogenase-like catalytic domain of Pah1. …”
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Auditory Stimulation Dishabituates Olfactory Responses via Noradrenergic Cortical Modulation by Jonathan J. Smith, Kiseko Shionoya, Regina M. Sullivan, Donald A. Wilson

“…Finally, blockade of piriform cortical norepinephrine ß-receptors with bilateral intracortical infusions of propranolol (100 μM) disrupts auditory-induced dishabituation of odor-evoked bradycardia responses. …”
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Administration of anticoagulation strategies for portal vein thrombosis in cirrhosis: network meta-analysis by Hui-Jun Li, Fu-Qiang Yin, Yu-Tong Ma, Teng-Yu Gao, Yu-Ting Tao, Xin Liu, Xian-Feng Shen, Chao Zhang

“…The TIPS plus warfarin, LMWH-DOACs sequential, and TIPS improved the complete recanalization rate most effectively, and the EBL plus propranolol, heparin plus DOACs plus warfarin, and DOACs were highly recommended for increasing the incidence of partial recanalization. …”
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Cerebral Cavernous Malformation: From Genetics to Pharmacotherapy by Zhuangzhuang Zhang, Jianwen Deng, Weiping Sun, Zhaoxia Wang

“…Medications such as statins, fasudil, rapamycin, and propranolol can alleviate CCM symptoms or hinder its progression by specifically modulating the corresponding targets. …”
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Lack of Noradrenergic Modulation of Indirect Semantic Priming by Jacquelyne S. Cios, Regan F. Miller, Ashleigh Hillier, Madalina E. Tivarus, David Q. Beversdorf

“…Subjects attended three sessions: one each after propranolol (40 mg) (noradrenergic antagonist), ephedrine (25 mg) (noradrenergic agonist), and placebo. …”
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Paravertebral and Retroperitoneal Vascular Tumour Presenting with Kasabach-Merritt Phenomenon in Childhood, Diagnosed with Magnetic Resonance Imaging by Gonca Keskindemirci, Deniz Tuğcu, Gönül Aydoğan, Arzu Akçay, Nuray Aktay Ayaz, Ali Er, Ensar Yekeler, Bilge Bilgiç

“…Although we did not get any response to steroid or propranolol treatment, partial response was observed radiologically with interferon-alpha treatment. …”
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Interventions by Cardiovascular Drugs Against Aircraft Noise-Induced Cardiovascular Oxidative Stress and Damage by Marin Kuntić, Ivana Kuntić, Jiayin Zheng, Leonardo Nardi, Matthias Oelze, Arijan Valar, Dominika Mihaliková, Lea Strohm, Henning Ubbens, Qi Tang, Liyu Zhang, Guilherme Horta, Paul Stamm, Omar Hahad, Dilja Krueger-Burg, Huige Li, Sebastian Steven, Adrian Gericke, Michael J. Schmeisser, Thomas Münzel, Andreas Daiber

“…C57BL/6 mice were treated with the beta-blocker propranolol (15 mg/kg/d s.c. for 5 d) or the alpha-blocker phenoxybenzamine (1.5 mg/kg/d s.c. for 5 d) and noise-exposed for the last 4 d of the drug administration. …”
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Lithium as an Alternative Option in Graves Thyrotoxicosis by Ishita Prakash, Eric Sixtus Nylen, Sabyasachi Sen

“…High dose Hydrocortisone and propranolol were also administered concomitantly. Free thyroid hormone levels decreased and the patient reached a biochemical and clinical euthyroid state in about 8 days. …”
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A Rare Case of Thyrotoxic Periodic Paralysis in a Patient With Concomitant Methimazole-Induced Agranulocytosis by Kevin S. Wei, MD, Alexandra N. Lim, MD, Sophie M. Cannon, MD

“…She was admitted to the intensive care unit and started on broad-spectrum antibiotics, lithium, and propranolol for treatment of septic shock and hyperthyroidism, respectively. …”
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