Application of Computer Simulation in Exploring the Effects of <italic>Achyranthis Bidentatae Radix</italic> on Simultaneously Treating Wei Syndrome and Bi Syndrome of Osteoarthrit... by Chunsong ZHENG, Hongzhi YE, Jinxia YE, Changlong FU

“…In the compound-target network of Niuxi in treating Wei syndrome of OA, the key compound node of Niuxi was baicalin, which belonged to flavonoids, and the key target node was MMP-1.Conclusion:Computer simulation intuitively showed the multi-target effects of Niuxi in simultaneously treating Wei syndrome and Bi syndrome of OA through the modes like promiscuous drug and combination drug. This could provide a basis for Niuxi therapeutic for OA and new drug development from Niuxi.…”
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