Innovative epitopes in Staphylococcal Protein-A an immuno-informatics approach to combat MDR-MRSA infections by Pengjun Zhou, Pengjun Zhou, Xing Shi, Jinquan Xia, Yifei Wang, Shaowei Dong

“…In-silico analyses confirmed the antigenicity, promiscuity, and non-glycosylated nature of the selected epitopes.ResultsSeveral T and B cell epitopes within SpA were identified, showcasing high binding affinities and extensive population coverage. …”
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Broad substrate scope C-C oxidation in cyclodipeptides catalysed by a flavin-dependent filament by Emmajay Sutherland, Christopher J. Harding, Tancrède du Monceau de Bergendal, Gordon J. Florence, Katrin Ackermann, Bela E. Bode, Silvia Synowsky, Ramasubramanian Sundaramoorthy, Clarissa Melo Czekster

“…The enzyme exhibits promiscuity, processing various cyclic dipeptides as substrates in a distributive manner. …”
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Characterization and structural analysis of a versatile aromatic prenyltransferase for imidazole-containing diketopiperazines by Wenxue Wang, Peng Wang, Chuanteng Ma, Kang Li, Zian Wang, Yuting Liu, Lu Wang, Guojian Zhang, Qian Che, Tianjiao Zhu, Yuzhong Zhang, Dehai Li

“…The mutation experiments further demonstrate the promiscuity of AuraA towards imidazole-C-dimethylallylation. …”
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Flavonoids and anthocyanins in seagrasses: implications for climate change adaptation and resilience by Jana Botes, Jana Botes, Xiao Ma, Xiao Ma, Jiyang Chang, Jiyang Chang, Yves Van de Peer, Yves Van de Peer, Yves Van de Peer, Yves Van de Peer, Dave Kenneth Berger, Dave Kenneth Berger

“…Certain features, such as catalytic promiscuity and metabolon interactions, allow flavonoid metabolism to expand to produce novel compounds and respond to a variety of stimuli. …”
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Impact of predictive selection of LbCas12a CRISPR RNAs upon on‐ and off‐target editing rates in soybean by Linda Rymarquis, Chenxi Wu, Diane Hohorst, Miguel Vega‐Sanchez, Thomas E. Mullen, Vijetha Vemulapalli, Douglas R. Smith

“…Plants with a desired on‐target edit and no off‐target edits could be identified in the T1 generation for 100% of the T0 plants edited with the Unique crRNA compared with the 65% of T0 plants edited with the Promiscuous crRNA. This confirms that proper crRNA selection can reduce or eliminate off‐target editing. …”
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Modeling HIV outbreaks: The male to female prevalence ratio in the core population by Brandy Rapatski, James Yorke

“…We conclude that if the female core group was larger, that is, if more women in the total population were promiscuous (or if fewer men were promiscuous) then the HIV epidemic would grow more slowly.…”
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Danger theory inspired intrusion detection model for wireless sensor networks by Rong-rong FU, Kang-feng ZHENG, Tian-liang LU, Yi-xian YANG

“…According to the challenges of intrusion detection technique for wireless sensor networks,a danger theory in-spired intrusion detection model was proposed by taking advantage of the working principle of artificial immune system.Due to the distributed and cooperative mechanism,the proposed model shows more advantages in detection performance and energy consumption than methods adopt promiscuous to get global knowledge.The simulation results show that compared to traditional Watchdog algorithm with single threshold and self-nonself(SNS)model,the model inspired by danger theory can provide highest correct detection rate and lowest false detection rate.Moreover,the model can also decrease the energy consumption of the system.…”
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Indirect evidence of an early mating advantage in wild cooperatively breeding male banded mongooses by Graham Birch, Michael A. Cant, Hazel J. Nichols, Magali Meniri, Robert Businge, Francis Mwanguhya, Jonathan D. Blount

“…Abstract Promiscuous females reduce male reproductive control. …”
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Janet Flanner’s The Cubical City and the Life She Left Behind by Rai PETERSON

“…Flanner’s novel includes minor lesbian characters and sub-plots, yet on the surface it seems to be a heteronormative romance in which a promiscuous female character pursues marriage with an eligible bachelor. …”
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Mutations to transcription factor MAX allosterically increase DNA selectivity by altering folding and binding pathways by Renee Hastings, Arjun K. Aditham, Nicole DelRosso, Peter H. Suzuki, Polly M. Fordyce

“…Towards this end, we study how variants of the promiscuous transcription factor (TF) MAX (H. sapiens) alter DNA specificity and selectivity, yielding >1700 K ds and >500 rate constants in complex with multiple DNA sequences. …”
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Spectacle and Spectatorship at the Nineteenth-Century American Racetrack by Natalie Zacek

“…However, these audiences, unlike those who were both the subjects and the viewers of English artist William Powell Frith’s celebrated 1858 painting of Derby Day at Epsom Downs, experienced anxiety as well as entertainment from the proximity of “others,” particularly African-Americans (whether enslaved or free) and poor whites; they hoped that these groups would improve their manners by imitating those of their “betters,” but at the same time they, unlike the Epsom audiences, shied away from “crowds of the most promiscuous character.” Thus, the spectacle of human physical, social, and cultural diversity was simultaneously a source of pleasure and a harbinger of social discord.…”
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Advanced Mesodermal (Müllerian) Adenosarcoma of the Ovary: Metastases to the Lungs, Mouth, and Brain by A. Daskalaki, S. Xenaki, E. Athanasakis, E. Chrysos, G. Chalkiadakis

“…The imaging exams revealed a solid, promiscuous lesion of 16 × 14 cm in dimensions located into the small pelvis, surrounding the uterus and the ovaries. …”
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Mechanisms and Consequences of Dopamine Depletion-Induced Attenuation of the Spinophilin/Neurofilament Medium Interaction by Andrew C. Hiday, Michael C. Edler, Asma B. Salek, Cameron W. Morris, Morrent Thang, Tyler J. Rentz, Kristie L. Rose, Lisa M. Jones, Anthony J. Baucum

“…Phosphatases, such as protein phosphatase 1 (PP1), are highly promiscuous and obtain substrate selectivity via targeting proteins. …”
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PARENT COMMUNICATION PATTERNS AND RISK SEXUAL BEHAVIOR IN LATE ADOLESCENT by Cindy Wahyu Agustina, Sulistiawati Sulistiawati, Bagus Setyoboedi

“…Many factors can cause risky sexual behaviour, family factors, especially parental communication patterns are one of the most important influences, because parents are the environment that has the strongest preventive efforts in keeping adolescents involved in promiscuous activities. This study aims to find the relationship between parental communication patterns and risky sexual behaviour in late adolescents. …”
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Comparative 3D ultrastructure of Plasmodium falciparum gametocytes by Felix Evers, Rona Roverts, Cas Boshoven, Mariska Kea-te Lindert, Julie M. J. Verhoef, Nico Sommerdijk, Robert E. Sinden, Anat Akiva, Taco W. A. Kooij

“…We provide evidence that the ER is a promiscuous interactor with numerous organelles and the trilaminar pellicle of the gametocyte. …”
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The Psychological Impact of Divorce on Children in Manado City, North Sulawesi by Ardianto Ardianto, Edi Gunawan, Nasruddin Yusuf, Munir Tubagus

“…These psychological impacts are then reflected in various aspects of the child's life, including a decline in academic performance, lack of motivation to study, and deviant behaviors such as drug use or engaging in promiscuous activities. In facing these challenges, it is crucial for children to receive adequate social and psychological support. …”
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Differences according to Sex in Sociosexuality and Infidelity after Traumatic Brain Injury by Jhon Alexander Moreno, Michelle McKerral

“…TBI does not seem to have an impact on infidelity, but individuals with TBI who express less acceptance of infidelity also report a more promiscuous mating strategy regarding their behavior, attitudes, and desire. …”
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Computer Simulation on Analgesic Functional Chemome Characteristics of <italic>Radix Saposhnikoviae</italic> by Chunsong ZHENG, Xiaojie XU, Hongzhi YE, Jinxia YE, Guangwen WU, Xianxiang LIU

“…The functional chemome of RS had better multi-target effects compared with drug/drug-like molecules, and became an important source on mining promiscuous drugs from RS.…”
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Epstein-Barr virus reactivation induces divergent abortive, reprogrammed, and host shutoff states by lytic progression. by Elliott D SoRelle, Lauren E Haynes, Katherine A Willard, Beth Chang, James Ch'ng, Heather Christofk, Micah A Luftig

“…These data reveal previously unknown and promiscuous outcomes of lytic reactivation with broad implications for viral replication and EBV-associated oncogenesis.…”
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Computation Simulation Research of Bushen Zhuangjin Decoction on Multi-target Effects in Delaying Cataplasia of Articular Cartilage by Chunsong ZHENG, Xiaojie XU, Suixin HUANG, Hongzhi YE

“…Furthermore, the compounds in BSZJD work mainly by ways of promiscuous drug in the therapy of OA. This comes up an explanation about BSZJD therapeutical effect for OA based on the theory of"treatment for flaccidity aims at the origin". …”
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