The role of short-chain fatty acid in metabolic syndrome and its complications: focusing on immunity and inflammation by Wenqian Yu, Wenqian Yu, Siyuan Sun, Siyuan Sun, Qiang Fu

“…In addition, this study proposes novel strategies to modulate SCFA for the treatment of Mets that may help to mitigate the prognosis of Mets and its complications.…”
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Solid Pseudopapillary Neoplasms Are Rare, Indolent Pancreatic Tumors in Young Women by Amin Dalili, Mohsen Aliakbarian, Mehdi Karimi-Shahri, Alireza Samadi, Sara Raji

“…SPN is known as a tumor with a favorable prognosis and a long survival rate after complete resection. …”
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Prenatal Diagnosis of Isolated Agnathia-Otocephaly: A Case Report and Review of the Literature by Kazuhiro Kajiwara, Tomohiro Tanemoto, Chie Nagata, Aikou Okamoto

“…Because agnathia is associated with very poor prognosis, accurate prenatal diagnosis and detailed counseling should be promptly provided before unexpected delivery to the parents for the determination of postnatal treatment.…”
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Personalized Management in Low-Risk Prostate Cancer: The Role of Biomarkers by Siebren Dijkstra, Agus Rizal A. H. Hamid, Gisèle H. J. M. Leyten, Jack A. Schalken

“…The current discovered biomarkers could potentially guide in this management and improve detection, staging, and prognosis. This paper provides an overview of the current available serum-, urine-, and tissue-based biomarkers in PCa and evaluates the clinical usefulness of these biomarkers in the detection and management of low-risk PCa.…”
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Integrins identified as potential prognostic markers in osteosarcoma through multi-omics and multi-dataset analysis by Lei Cui, Shuai Zhao, Hai long Teng, Biao Yang, Qian Liu, An Qin

“…Abstract Osteosarcoma represents 20% of primary malignant bone tumors globally. Assessing its prognosis is challenging due to the complex roles of integrins in tumor development and metastasis. …”
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Refractory IgD Multiple Myeloma Treated with Daratumumab: A Case Report and Literature Review by Muhammad Husnain, Sandra Kurtin, Nikki Barkett, Irbaz bin Riaz, Amit Agarwal

“…Patients with relapsed and refractory multiple myeloma have poor prognosis. A recent analysis of patients with relapsed and refractory multiple myeloma who were refractory to both proteasome inhibitors and immunomodulatory drugs showed the median overall survival of 9 months only. …”
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Fulminant myocarditis caused by immune checkpoint inhibitor: a case report and possible treatment inspiration by Zhijie Liu, Yiming Fan, Jun Guo, Ning Bian, Dongdong Chen

“…The intriguing observation that the patient condition recovered relatively rapidly in this case shows a possible treatment inspiration, which may be helpful for treating ICIs‐associated myocarditis and improving cancer patients' clinical prognosis.…”
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Gut-Lung Microbiota in Chronic Pulmonary Diseases: Evolution, Pathogenesis, and Therapeutics by Chang Yi Shi, Chen Huan Yu, Wen Ying Yu, Hua Zhong Ying

“…Gut microbiota affects respiratory immunity and barrier function through the lung-gut microbiota, resulting in altered prognosis of chronic respiratory diseases. In turn, lung dysbiosis promotes aggravation of lung diseases and causes intestinal dysfunction through persistent activation of lymphoid cells in the body. …”
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Complete Radiologic Response of Metastatic Pancreatic Ductal Adenocarcinoma to Microwave Ablation Combined with Second-Line Palliative Chemotherapy by Hakon Blomstrand, Karin Adolfsson, Per Sandström, Bergthor Björnsson

“…Pancreatic ductal adenocarcinoma (PDAC) has a bleak prognosis, especially for the majority of patients diagnosed with metastatic disease. …”
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Gender and Ocular Manifestations of Connective Tissue Diseases and Systemic Vasculitides by Maria M. Choudhary, Rula A. Hajj-Ali, Careen Y. Lowder

“…There is a slight female preponderance in sarcoidosis with female gender carrying a worse prognosis in the outcome of ocular disease.…”
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Prevalence of dual diagnosis in the south of Peru: descriptive clinical study by Jonathan A. Zegarra-Valdivia, Brenda Nadia Chino Vilca, Ernesto Cazorla Perez

“…The socio-family and individual vulnerability of the population is evidence for protection or resistance to mental illness, as well as the lack of implementation of effective policies in mental health care for dual disorders, showing worse prognosis and indexes every time higher.…”
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Intrahepatic Cholestasis in Non-Alcoholic Fatty Liver Disease: Pathogenesis and Role of Ademetionine in Treatment by Ye. N. Shirokova

“…Concomitant IHC is present in 30 % of NAFLD patients, while it is associated with more active disease course and possible worsening of prognosis. Impairment of adipocyte and hepatocyte metabolism, gut dysbiosis, and inherent factors are recognized as significant factors for NAFLD development. …”
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Rat models of frozen shoulder: Classification and evaluation by Hezirui Gu, Wenqing Xie, Hengzhen Li, Shuguang Liu, Yusheng Li

“…These symptoms and poor prognosis affect people's physical health and quality of life. …”
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Role of SarA in Staphylococcus aureus: A Virulence Target For Therapeutic Strategies by Yi He Kuai, Jodi Woan-Fei Law, Yong Sze Ong, Vengadesh Letchumanan, Learn-Han Lee, Loh Teng-Hern Tan

“… Methicillin-resistant Staphylococcus aureus (MRSA) infection gives rise to significant morbidity and carries a grave prognosis, resulting in the demise of approximately 21.8% of afflicted individuals on a yearly basis Staphylococcus aureus has the capability to induce a myriad of diverse diseases, a phenomenon attributed to its extensive array of virulence factors and formation of biofilms. …”
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Expert Opinion on Fixed Dose Combination of Dapagliflozin Plus Sitagliptin for Unmet Cardiovascular Benefits in Type 2 Diabetes Mellitus by Soumitra Ray, J Ezhilan, Rajiv Karnik, Ashish Prasad, Rajashree Dhar

“…The coexistence of T2DM with established/risk of atherosclerotic cardiovascular disease (ASCVD), heart failure (HF), or chronic kidney disease confers a poor prognosis, and management can be challenging. Guidelines recommend clinicians to consider CV/HF risk, renal/hepatic risk, and other comorbidities while choosing an antidiabetic regimen. …”
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Anal Canal Duplication in an 11-Year-Old-Child by S. Van Biervliet, E. Maris, S. Vande Velde, D. Vande Putte, V. Meerschaut, N. Herregods, R. De Bruyne, M. Van Winckel, K. Van Renterghem

“…We present the clinical history of an eleven-year-old girl with ACD followed by a review of symptoms, diagnosis, treatment, and prognosis based on all the reported cases in English literature.…”
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Unveiling the impact of CD133 on cell cycle regulation in radio- and chemo-resistance of cancer stem cells by Luyao Wu, Luyao Wu, Takanori Katsube, Xiaofei Li, Bing Wang, Yi Xie

“…The aim of this review is to provide a foundational understanding of how these signaling pathways and their interactions impact cancer prognosis and inform treatment strategies.…”
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Undifferentiated Intimal Sarcoma of the Inferior Vena Cava with Extension to the Right Atrium and Renal Vasculature by Aasim M. Afzal, Jamil Alsahhar, Varsha Podduturi, Jeffrey M. Schussler

“…Intimal sarcomas tend to carry a poor prognosis with the limited literature available on treatment approaches. …”
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The Inhibitory Role of B7-H4 in Antitumor Immunity: Association with Cancer Progression and Survival by Changjun He, Haiquan Qiao, Hongchi Jiang, Xueying Sun

“…The paper also discusses the clinical significance of investigating B7-H4 as potential markers for cancer diagnosis and prognosis, and as therapeutic targets.…”
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Analysis of Cause-Specific Mortality in Patients with Retinoblastoma by Lei Yang, Xiaolian Fang, Mei Jin, Jun Chen, Chengyue Zhang, Jianing Mou, Junyang Zhao, Xin Ni

“…Retinoblastoma (RB) is a rare pediatric tumor with a relatively favorable prognosis. However, RB is associated with cause-specific mortality, some of that should be of great importance to clinicians. …”
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