Mandibular Canal Widening and Bell’s Palsy: Sequelae of Perineural Invasion in Oral Cancer by Gopinath Thilak Parepady Sundar, Vishwanath Sherigar, Sameep S. Shetty, Shree Satya, Sourabh M. Gohil

“…Perineural invasion is a marker of poor prognosis. Oral submucous fibrosis with oral cancer constitutes a clinicopathologically distinct disease. …”
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Biological functions of 5-methylcytosine RNA-binding proteins and their potential mechanisms in human cancers by Tingting Zhao, Zhe Zhang, Zhuo Chen, Guozheng Xu, Yongxi Wang, Fang Wang

“…By affecting the proliferation, migration, invasion, and drug sensitivity of tumor cells, m5C methylation modification plays a vital part in the initiation and progression of tumors and is closely associated with the poor tumor prognosis. m5C-related proteins are categorized into three functional groups: m5C methyltransferases (m5C writers), m5C demethylases (m5C erasers), and m5C methyl-binding proteins (m5C readers). …”
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Bilateral Serous Psammocarcinoma of Ovary: Rare Variant Low Grade Serous Carcinoma by Saubhagya Kumar Jena, Pritinanda Mishra, Vandana Mohapatra, Sweta Singh

“…Its clinical behavior is similar to serous borderline tumors with relatively favorable prognosis. We report herein a case of a 60-year-old postmenopausal woman who presented with abdominal distension. …”
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Role of Vitamin D in the Prevention of Pancreatic Cancer by Pubudu Bulathsinghala, Kostas N. Syrigos, Muhammad W. Saif

“…Pancreatic cancer is a malignancy of poor prognosis which is mostly diagnosed at advanced stages. …”
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Clinicopathological Features of Meningioangiomatosis Associated with Meningioma: A Case Report with Literature Review by Huajuan Cui, Huijuan Shi, Xiaodong Chen, Wei Wang, Riquan Lai, Anjia Han

“…Patients with MA associated with meningioma often have a good prognosis after operation.…”
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Hemolytic Uremic Syndrome Associated with Pneumococcal Pneumonia. A Case Report by Ariel Efrén Uriarte Méndez, Andrés Prieto Apesteguía, Jesús Vila Díaz, Jorge Luis Capote Padrón, Kendrie Villavicencio Cardoso, Alnilam Fernández González

“…In its classic form it is associated with diarrhea and it has a good prognosis. When there is an invasive pneumococcal disease as underlying condition, it has a mortality rate of 25%, and half of the surviving cases develop end-stage renal disease (ESRD). …”
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Cardiac Dedifferentiated Liposarcoma Requiring a Mitral Valve Replacement Complicated by Severe Paravalvular Leak: A Rare Case Report with Literature Review by Anju Adhikari, Adam Hafeez, Alexandra Halalau

“…Cardiac sarcomas have a high infiltrative and metastatic potential and are often associated with poor prognosis. These tumors are often identified incidentally by thoracic and cardiac imaging. …”
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The Operative Challenges of Advanced Renal Cell Carcinoma with Vena Cava Involvement: A Report of Three Cases by Muftau Jimoh Bioku, Abdulwaid Niran Saliu, Stephen Odunayo Ikuerowo, Olufunmilade Omisanjo, Julius Olusanmi Esho

“…For over three decades now, researchers in Lagos had recorded the abysmal prognosis of advanced cases of RCC. Yet, late presentation and diagnosis still persisted in our environment. …”
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Recent Advances, Research Trends, and Clinical Relevance of Hyaluronic Acid Applied to Wound Healing and Regeneration by Gloria Huerta-Ángeles, Edgar Mixcoha

“…The synthesis/catabolism of HA is critical in several pathologies and has been used as a marker for the prognosis of cancers. Among its physiological roles, HA is used for wound healing applications. …”
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Multiple Intracranial Meningiomas: A Review of the Literature and a Case Report by F. Koech, J. Orege, F. Ndiangui, B. Macharia, N. Mbaruku

“…Incidence varies from 1 to 10%. The prognosis of multiple intracranial meningioma does not differ from benign solitary meningiomas despite the multiplicity. …”
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Adult onset wilms tumor by Madhangi Parameswaran, MBBS, Alison M. Friedmann, MD, Gregory M. Cote, MD, PhD, Keyan Salari, MD, PhD, Mukesh G. Harisinghani, MD, Rory L. Cochran, MD, PhD

“…In contrast, WT in adults is extremely rare and is associated with a poorer prognosis. The clinical presentation and imaging features of WT in adults are nonspecific and overlap with other more common forms of renal cancer, often leading to a delay in diagnosis. …”
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A Review of Routine Laboratory Biomarkers for the Detection of Severe COVID-19 Disease by Keynaz Keykavousi, Fahimeh Nourbakhsh, Nooshin Abdollahpour, Farzaneh Fazeli, Alireza Sedaghat, Vahid Soheili, Amirhossein Sahebkar

“…As the COVID-19 pandemic continues, there is an urgent need to identify clinical and laboratory predictors of disease severity and prognosis. Once the coronavirus enters the cell, it triggers additional events via different signaling pathways. …”
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Intrinsic subtype and immunity score in identification of triple-negative breast cancer at low risk by Xinyu Ren, Tong Zhou, Yu Song, Huanwen Wu, Jeff Chou, Lance D. Miller, Zhiyong Liang, Songjie Shen

“…Despite majority of them had the unfavorable prognosis, a subset of patients who do not receive chemotherapy exhibit a good prognosis. …”
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3D synergistic tumor-liver analysis further improves the efficacy prediction in hepatocellular carcinoma: a multi-center study by Yurong Jiang, Jiawei Zhang, Zhaochen Liu, Jinxiong Zhang, Xiangrong Yu, Danyan Lin, Dandan Dong, Mingyue Cai, Chongyang Duan, Shuyi Liu, Wenhui Wang, Yuan Chen, Qiyang Li, Weiguo Xu, Meiyan Huang, Sirui Fu

“…Abstract Background Besides tumorous information, synergistic liver parenchyma assessments may provide additional insights into the prognosis of hepatocellular carcinoma (HCC). This study aimed to investigate whether 3D synergistic tumor-liver analysis could improve the prediction accuracy for HCC prognosis. …”
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Nucleated red blood cells for characterization of systemic inflammatory response syndrome in dogs by ARom Cho, Hyeona Bae, Youngju Kim, Yeseul Jeon, Rankyung Jung, Minji Kim, Minjeong Kang, Sumin Cha, Kyu‐Woan Cho, Dong‐In Jung, Jinho Park, DoHyeon Yu

“…Objectives To evaluate the utility of nRBCs as a marker of disease severity and prognosis in dogs with systemic inflammatory response syndrome (SIRS). …”
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Long-Term Clinical Outcomes for Non-ST Elevation Acute Coronary Syndrome Patients with High-Risk Angiographic Findings Undergoing Percutaneous Coronary Intervention by Sida Jia, Ce Zhang, Yue Liu, Deshan Yuan, Xueyan Zhao, Runlin Gao, Yuejin Yang, Bo Xu, Zhan Gao, Jinqing Yuan

“…We aim to evaluate the long-term prognosis of non-ST elevation acute coronary syndrome (NSTE-ACS) patients with high-risk coronary anatomy (HRCA). …”
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Heterogeneous nuclear ribonucleoprotein C promotes non-small cell lung cancer progression by enhancing XB130 mRNA stability and translation by Qinrong Wang, Xuanjing Gou, Lingling Liu, Daolan Deng, Yan Zhao, Jianjiang Zhou, Yuan Xie, Yinhui Jiang, Jianglun Li, Jian Zhang, Ying Liu

“…Materials and methods We evaluated the expression of hnRNPC in cancer and assessed the correlation between hnRNPC expression and prognosis in cancer patients using public databases. …”
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Lipoxin A4 levels correlate with severity in a Spanish COVID-19 cohort: potential use of endogenous pro-resolving mediators as biomarkers by Sergio Sánchez-García, Rafael I. Jaén, Roberto Lozano-Rodríguez, José Avendaño-Ortiz, Alejandro Pascual‐Iglesias, Laura Hurtado-Navarro, Eduardo López-Collazo, Eduardo López-Collazo, Lisardo Boscá, Lisardo Boscá, Patricia Prieto, Patricia Prieto, Patricia Prieto

“…Some of them present a very severe phenotype, while others only experience mild symptoms or are even asymptomatic. This differential prognosis is tightly related to the inflammatory status of the patient. …”
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An integrative analysis of ASCL1 in breast cancer and inhibition of ASCL1 increases paclitaxel sensitivity by activating ferroptosis via the CREB1/GPX4 axis by Xiaolu Yang, Xiaolu Yang, Yilun Li, Yilun Li, Yaqi Peng, Yuan Chang, Binglu He, Binglu He, Tianqi Zhang, Tianqi Zhang, Shiyu Zhang, Cuizhi Geng, Yunjiang Liu, Xiaolong Li, Jun Hao, Li Ma

“…Functional assays were conducted on BC cell lines MCF-7 and MDA-MB-231, and nude mouse models were used for in vivo studies.ResultsASCL1 was found to be upregulated in BC and correlated with unfavorable prognosis and mutations in key oncogenes. Its expression was linked to immunomodulatory factors, immune cell infiltration, and immunoreactivity scores in the tumor microenvironment. …”
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Integrated bioinformatics analysis to explore potential therapeutic targets and drugs for small cell carcinoma of the esophagus by Maofei Zhu, Maofei Zhu, Yueming Chu, Yueming Chu, Qiang Yuan, Qiang Yuan, Junfeng Li, Silin Chen, Lin Li, Lin Li, Lin Li

“…BackgroundSmall cell carcinoma of the esophagus (SCCE) is a rare form of esophageal cancer, which also belongs to the category of neuroendocrine malignant tumors, with a low incidence but high aggressiveness, and a very poor prognosis for patients. Currently, there is a lack of unique staging and treatment guidelines for SCCE. …”
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