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1721
A new prognostic model for predicting overall survival and progression-free survival in unresectable hepatocellular carcinoma treated with the FOLFOX-HAIC regimen based on patient...
Published 2025-01-01“…Subsequently, the model was used to develop a nomogram to predict the individualized prognosis of patients with u-HCC treated with the FOLFOX-HAIC, with a higher net benefit than the TMN staging. …”
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1722
The miR-1269a/PCDHGA9/CXCR4/β-catenin pathway promotes colorectal cancer invasion and metastasis
Published 2024-11-01“…Low expression of PCDHGA9 potentially correlated with worse prognosis and increased chances of invasion and metastasis in CRC. miR-1269a was highly expressed in CRC tissues and acted as a negative regulator for PCDHGA9, promoting invasion, migration, and EMT of CRC cells. …”
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1723
Soluble ST2 protein as a new biomarker in patientswith precapillary pulmonary hypertension
Published 2020-09-01“…Significant correlations were found between sST2 and hemodynamic parameters: mean right atrial pressure (r = 0.56; p < 0.05), mean pulmonary artery pressure (r = 0.25; p < 0.05), cardiac index (r = –0.40; p < 0.05), pulmonary vascular resistance (r = 0.41; p < 0.05), and between sST2 and WHO FC (r = 0.36; p < 0.05), NT-proBNP (r = 0.55; p < 0.05), and TnT (r = 0.44; p < 0.05). sST2 concentration above the median was associated with worse clinical prognosis (p = 0.02, Kaplan-Meier). Conclusions sST2 seems to be a marker of poor clinical prognosis in patients with PH.…”
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1724
Characterization and Detection Strategy Exploration in Cryptogenic Hepatocellular Carcinoma: Insights From a Super‐Aged Region in Japan
Published 2025-01-01“…Within the cohort of c‐HCC, the prognosis for symptomatic cases is notably unfavorable compared to other cases [median survival time 19.0 (7.0–45.0) months vs. 47.0 (29.0–76.0) months, p = 0.029]. …”
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1725
Evaluation of patient immunocompetence for immune checkpoint inhibitor therapy using the psoas muscle index: a retrospective cohort study
Published 2025-02-01“…IntroductionIn patients with cancer, sarcopenia is an indicator of poor prognosis and is associated with an increased risk of chemotherapy-related adverse events. …”
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1726
Impact of Bone-Modifying Agents on Post-Bone Metastasis Survival Across Cancer Types
Published 2025-01-01“…Background: Bone metastasis is associated with a poor prognosis. Bone-modifying agents (BMA) are commonly used for the prevention or treatment of skeletal-related events (SRE) in patients with bone metastasis; however, whether or not treatment with BMA improves survival remains unclear. …”
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1727
Clinicopathological Significance of FOXO4 Expression and Correlation with Prx1 in Head and Neck Squamous Cell Carcinoma
Published 2021-01-01“…FOXO4 could be a potential molecular target for the treatment and prognosis of HNSCC.…”
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1728
The clinical significance of T cell infiltration and immune checkpoint expression in central nervous system germ cell tumors
Published 2025-01-01“…Additionally, the study explored the relationship between these immune features and the patient’s clinical characteristics and prognosis.ResultsThe study revealed that germinomas exhibited significantly higher infiltration of CD4+ and Foxp3+ T cells compared to non-germinomatous GCTs (NGGCTs). …”
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1729
High-fat diet promotes gestational diabetes mellitus through modulating gut microbiota and bile acid metabolism
Published 2025-01-01“…HFD induced GDM and contributed to poor prognosis in GDM parturients through inducing gut microbial dysbiosis and metabolic alteration, especially appeared in BAs profile. …”
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1730
Karakteristik Klinis dan Patologis Karsinoma Nasofaring di Bagian THT-KL RSUP Dr.M.Djamil Padang
Published 2016-01-01“…<div class="WordSection1"><p><strong>Abstrak</strong></p><p>Karsinoma nasofaring banyak terjadi di Cina dan Asia Tenggara, termasuk di Indonesia, sering didiagnosis pada keadaan lanjut dan memiliki prognosis yang buruk. Tujuan penelitian ini adalah untuk mengevaluasi epidemiologi, karakteristik klinis, dan tipe histopatologi pada pasien karsinoma nasofaring di Bagian THT-KL. …”
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1731
PPAR-Alpha Agonist Fenofibrate Combined with Octreotide Acetate in the Treatment of Acute Hyperlipidemia Pancreatitis
Published 2021-01-01“…The synergistic inhibitory effect proves that the combined treatment is beneficial to control inflammation, protect liver function, and improve the prognosis of patients. It is worthy of clinical promotion.…”
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1732
A Serious Case of Poisoning Caused by Oral Ingestion of Water-Soluble Fertilizer
Published 2024-10-01“…Although the damage was severe, the patient quickly recovered to normal after appropriate treatment. The prognosis is very good. This successful case provides guidance for clinical treatment.…”
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1733
Treatment of a Vertical Root Fracture Using Dual-Curing Resin Cement: A Case Report
Published 2012-01-01“…Vertical root fracture (VRF) is one of the most frustrating complications of root canal treatment. The prognosis of the root with VRF is poor therefore tooth extraction and root amputation are usually the only treatment options. …”
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1734
Low-Grade Malignant Triton Tumor of the Neck: A Case Report and Review of the Literature
Published 2014-01-01“…Rhabdomyoblastic differentiation in a malignant peripheral nerve sheath tumor (MPNST) is termed malignant triton tumor (MTT), a rare neoplasm that poses a diagnostic dilemma in the differential diagnosis of neck masses and portends poor prognosis. We report a sporadic case of MTT of the neck in a 23-year-old female. …”
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1735
Histological Evaluation of Internal Dental Resorption: An Analysis of a Cohort of 50 Cases
Published 2024-01-01“…A descriptive study involved the examination of 50 human teeth extracted due to an unfavorable prognosis for retention in the oral cavity. Teeth were preserved in 10% buffered formalin and subsequently subjected to the decalcification process. …”
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1736
Integrative prognostic modeling of ovarian cancer: incorporating genetic, clinical, and immunological markers
Published 2025-02-01“…High-risk patients demonstrated poor prognosis, greater immune checkpoint expression, and higher tumor mutational burdens (TMB), suggesting potential responsiveness to immunotherapy. …”
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1737
The impact of cardiac complications on COVID-19 outcomes
Published 2024-08-01“…Cardiovascular diseases are common risk factors for various infectious diseases, including COVID-19, and are also predictors of poor in-hospital and long-term prognosis. Possible mechanisms of cardiac damage are the high affinity of the SARS-CoV-2 adhesion protein to angiotensin-converting enzyme 2 receptors, cytokine storm, ischemia, inflammation, and acute respiratory distress syndrome. …”
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1738
Mesonephric-like adenocarcinoma of the uterine corpus with focal sarcomatous differentiation: A case report
Published 2025-02-01“…A diagnosis is made at an advanced stage in comparison with other histological types of uterine corpus cancer, and the prognosis is reportedly poor with high-level malignancy. …”
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1739
Autoimmune encephalitis: case reports of anti-NMDAR and anti-CASPR2 encephalitides and literature review
Published 2021-12-01“…In clinical practice, neuronal antibodies remain the most significant diagnostic marker currently available. Prognosis of AE varies greatly depending on the subtype and the time of immunotherapy initiation. …”
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1740
Familial Atypical Hemolytic Uremic Syndrome: A Review of Its Genetic and Clinical Aspects
Published 2012-01-01“…This understanding has culminated in the use of Eculizumab as first-line therapy in disease treatment, significantly changing the care and prognosis of affected patients. However, even with this bright outlook, major challenges remain to understand the complexity of aHUS at the genetic level. …”
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