Carcinosarcoma of the Rectum: Report of a Rare Colorectal Malignancy and Review of the Literature by Alexis Sudlow, Ming Ho Liu, Geoffrey Waters, Vamsi R. Velchuru

“…Clinically, it is a very aggressive tumour with many patients presenting with metastatic lymph nodes or distant metastases at the time of diagnosis. Prognosis is poor despite intervention with the majority of patients dying within six months. …”
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Revolutionizing acute myeloid leukemia treatment: a systematic review of immune-based therapies by Ugochi Ebinama, Binsah George

“…Abstract The established protocol for the management of acute myeloid leukemia (AML) has traditionally involved the administration of induction chemotherapy, followed by consolidation chemotherapy, and subsequent allogeneic stem cell transplantation for eligible patients. However, the prognosis for individuals with relapsed and refractory AML remains unfavorable. …”
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Primary Pleomorphic Liposarcoma of Liver: A Case Report and Review of the Literature by P. R. Thippeswamy Naik, Prem Kumar, P. Vinod Kumar

“…The knowledge of the clinical course, management, and prognosis of primary liver liposarcoma are all limited because of its rarity. …”
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Recent Advances in Antiviral Therapy for Chronic Hepatitis C by Akihiro Tamori, Masaru Enomoto, Norifumi Kawada

“…DAA treatment failure and prognosis after DAA therapy are also discussed.…”
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High-Dose Methotrexate for the Treatment of Relapsed Central Nervous System Erdheim-Chester Disease by Prahlad Ho, Carole Smith

“…CNS involvement is a major complication, which is often rapidly progressive and confers a poor prognosis. However, treatment of CNS ECD is difficult due to poor CNS penetrance by the most effective chemotherapeutic drugs commonly used in this disorder (e.g., interferon and cladribine). …”
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Diffuse Panbronchiolitis in a Caucasian Man in Canada by Alessandra Sandrini, MS Balter, Kenneth R Chapman

“…It usually affects nonsmokers and manifests as persistent air flow obstruction, chronic cough and interstitial nodular opacities. Untreated, the prognosis is poor. In this report the authors describe a Caucasian man of Canadian descent who presented with progressive clinical and lung function impairment despite three years of bronchodilator and corticosteroid treatment with presumed asthma. …”
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Burkitt lymphoma affecting the right heart. A case from practice by R.M. Vitovsky, V.P. Zakharova, O.А. Lozovyy, V.V. Isaenko, O.A. Pishchurin

“…By the time of the diagnosis, patients already have regional or distant metastases, which greatly worsens their clinical condition and the prognosis of surgical treatment. Hospital mortality in patients with malignant neoplasms is 25–50 %. …”
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Purple Urine Bag Syndrome: An Alarming Hue? A Brief Review of the Literature by Fahad Khan, Muhammad A. Chaudhry, Noorulain Qureshi, Benjamin Cowley

“…We hereby present a concise review of this rare phenomenon with historic perspectives, epidemiology, emphasizing on current concepts of etiology, pathogenesis, relevant clinical associations, treatment modalities, prognosis, and future directions in PUBS. In addition, we highlight an interesting occurrence of this intriguing phenomenon in a 39-year-old gentleman at our institution.…”
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Malignant Pleural Mesothelioma. Case Report and Literature Review by Samuel Sánchez Sánchez, Liz María Calvo Díaz, Ana Laura Navarro Baldellot

“…They have a low incidence and poor prognosis. A 46-years-old patient, white-skinned, who attended the Dr. …”
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Survival from Maternal Cardiac Arrest Complicating Coronavirus Disease 2019 by Andrea D. Shields, John J. Byrne, Meghan Munisteri, Michael Wood

“…Coronavirus disease 2019 (COVID-19) has been linked to significant cardiovascular complications such as cardiac arrest, which are associated with a poor prognosis in adults. Little is known about the cardiac complications, specifically cardiac arrest, of COVID-19 during pregnancy and postpartum periods. …”
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A Combination of Tachycardia-Mediated Heart Failure and Coronary Artery Vasospasm-Induced Silent Myocardial Infarction in a Patient with Severe Thyrotoxicosis by Serena Sert Kim Khoo, Chong Mow Chu, Yin Khet Fung

“…This life-threatening consequence has an excellent prognosis if recognised early and treated promptly.…”
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Extranodal natural killer/T cell lymphoma nasal type simulating osteoradionecrosis with metachronic B lymphoma in the pelvis: Case report by Frida S. Colín-Guadarrama, Violeta E. Flores-Solano, Argelia Berenice-Rodríguez, Víctor H. Toral-Rizo

“…Extranodal Natural Killer/T Cell Lymphoma Nasal Type (EN-NK/T-CL-NT) is a non-Hodgkin extranodal lymphoma of unfavorable prognosis due to its aggressive nature. This neoplasm mainly affects the paranasal sinuses, nasopharynx, oropharynx, oral cavity, palate, and rarely intestinal, gastric and skin regions. 50-year-old female with a history of lymphoma in nasal and pelvic region. …”
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MENINGIOMAS IN DOGS: EPIDEMIOLOGY, ADVANCEMENTS IN DIAGNOSTIC IMAGING AND THERAPEUTIC OPTIONS by Sorin Marian Mârza, Radu Lăcătuș, Felix Daniel Lucaci, Robert Cristian Purdoiu

“…This review underscores the necessity for advanced diagnostic capabilities and tailored treatment strategies to improve prognosis and quality of life in affected dogs.…”
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The Role of Cytokines in Nephrotic Syndrome by Elham Ahmadian, Yalda Rahbar Saadat, Elaheh Dalir Abdolahinia, Milad Bastami, Mohammadali M. Shoja, Sepideh Zununi Vahed, Mohammadreza Ardalan

“…Glucocorticoids are the primary therapy for INS; however, steroid-resistant NS (SRNS) patients are at a higher risk of drug-induced side effects and harbor poor prognosis. Although the exact mechanism of the resistance is unknown, the imbalances of T helper subtype 1 (Th1), Th2, and regulatory T cells (Tregs) and their cytokines may be involved in the pathogenesis of glucocorticoid responsiveness. …”
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Utility of pattern-based approach to skin biopsies in pediatric non-infectious inflammatory diseases: a review of 140 cases by Neha Singh, Suravi Mohanty, Rajalakshmi Tirumalae

“…Background Skin diseases constitute a significant burden in the pediatric age group and demand a separate evaluation from adult dermatoses as both vary in mode of presentation, prognosis, and line of treatment. Objective To evaluate the histopathologic spectrum of skin biopsies in pediatric noninfectious inflammatory diseases pediatric inflammatory diseases and its correlation with clinical findings. …”
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A Rare Case of Multifocal Papillary Thyroid Cancer in Bilateral Thyroid Cysts by Anupama Roy Chowdhury, Jack Kian Ch’ng, Choon Chieh Tan

“…In its more aggressive form, PTC may be multifocal in nature and is associated with a poorer prognosis. In patients whom PTC is diagnosed incidentally after a diagnostic lobectomy, the decision whether to offer completion thyroidectomy is sometimes challenging to make if such patients fall in the ‘low-to-intermediate’ risk category. …”
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Relation of Subjective Quality of Life to Motor Symptom Profile in Parkinson's Disease by Erica R. Appleman, Karina Stavitsky, Alice Cronin-Golomb

“…Determining reliable subtypes of PD may aid in prognosis and treatment optimization, thereby enhancing quality of life in afflicted individuals.…”
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Primary biliary cirrhosis: clinical and laboratory criteria of diagnostics and up-to-date treatment by L. Yu. Il’chenko, V. I. Reshetn’yak

“…АМА-positive (classical) variant of PBC with pruritus, jaundice, biochemical syndrome of cholestasis and revealing of AMA in diagnostic titer (more 1:40) in blood serum is defined; АМА-negative variant of PBC with lower biochemical and immunologic activity, lower frequency of extrahepatic manifestations, that, however, does not influence the prognosis and terms of LC progression; overlap syndrome with autoimmune hepatitis (AIH) – PBC/AIH (9,4%); asymptomatic course of PBC which is characterized by absence of clinical symptoms for a long period and manifestation of disease at the stage of LC complications. …”
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Cupriavidus gilardii infection following heart failure: a case report and literature review by Yanwen Liu, Jianxin Gao, Jingyun Ye, Hui Han, Haiyan Zhu

“…Monitoring heart function and selecting effective antibiotics are crucial for improving the prognosis of patients suffered from heart disease and Cupriavidus gilardii infection.…”
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New Insights about Pulmonary Epithelioid Hemangioendothelioma: Review of the Literature and Two Case Reports by Romeu Duarte Mesquita, Marta Sousa, Carmen Trinidad, Eugénia Pinto, Iosu Antón Badiola

“…Although the prognostic factors for PEH have not yet been well established, a better prognosis is usually associated with the multinodular pattern. …”
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