Cardiac injury caused by iron overload in thalassemia by Chunxi Fu, Chunxi Fu, Xue Yang, Xue Yang

“…Early identification and intervention for cardiac injury and iron overload in β-thalassemia have the potential to prevent and reverse or delay its progression in the early stages, playing a crucial role in its prognosis.…”
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Two Cases of Allergic Fungal Sinusitis with Differing Postoperative Course by Yuma Matsumoto, Hidenori Yokoi, Michitsugu Kawada, Masachika Fujiwara, Koichiro Saito

“…Case 2 showed a benign prognosis without recurrence. Close long-term follow-up should be mandatory after surgery for the treatment of AFS.…”
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A Primer on the Role of TP53 Mutation and Targeted Therapy in Endometrial Cancer by Bohao Zhang, Haozhe Zhang, Yanru Qin

“…The changes in the TME subsequently promote the development of tumors and assist in immune escape by tumor cells, making it more challenging to treat EC and resulting in a poor prognosis. Therefore, it is important to understand the effects of TP53 mutation in EC and to conduct further research in relation to the targeting of TP53 mutations. …”
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Combined Cerebellar and Spinal Cord Deficits Caused by an Underlying Gynecologic Malignancy by Tamer Othman, Moshe-Samuel Hendizadeh, Ritika Vankina, Susan Park, Phyllis Kim

“…Although cerebellar signs are characteristic of anti-Yo PCD, myelopathy is an unusual presentation of anti-Yo PCD based on published case series and reports. Unfortunately, the prognosis for anti-Yo PCD is often poor, and most patients become bedridden. …”
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Malignant Peripheral Nerve Sheath Tumors of the Head and Neck: A Case Series and Literature Review by Brandon T. Mullins, Trevor Hackman

“…Malignant peripheral nerve sheath tumors (MPNSTs) of the head and neck are rare aggressive neoplasms with a poor prognosis. This study describes the management and outcomes of 3 of our patients with MPNSTs of the head and neck. …”
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MELANOMAS, SARCOMAS, AND RENAL METASTASES IN THE LIVER: HOW TO TREAT? by Angelica Maria LUCCHESE, Antonio Nocchi KALIL, Alessandro L. DINIZ, Karl J. OLDHAFER, Timothy M. PAWLIK, René ADAM, Olivier SOUBRANE, Maria Ignez BRAGHIROLI, Ricardo Lemos COTTA-PEREIRA

“…ABSTRACT Liver metastases from melanomas, sarcomas, and renal tumors are less frequent. Treatment and prognosis will depend on whether they are isolated or multiple, size and location, the presence or absence of extrahepatic neoplastic disease, age, stage of the initial disease, initial treatments instituted, time of evolution, and clinical condition of the patient. …”
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A Man with Unilateral Endophthalmitis: A Case of Disseminated Nocardiosis by N. Navarrete-Navarrete, J. Escobar Sevilla, M. Toribio García, F. Urbano, J. M. Sabio, J. Jiménez-Alonso

“…In these cases it is very important to make an early diagnosis and intensive treatment to prevent the visual prognosis.…”
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Primary Carcinoma in Squamous Cells of the Gallbladder by Javier Martínez Navarro, Virgen Yazmín Martínez Navarro, Lisanka Fumero Roldán

“…Cancer in the gallbladder is infrequent. Its prognosis is related to the early detection and the degree of its penetration in the bladder wall. …”
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The mitochondria as an emerging target of self-renewal in T-cell acute lymphoblastic leukemia by Majd A. Al-Hamaly, Evelyn Winter, Jessica S. Blackburn

“…Despite advancements in the treatment of T-ALL, patients still face a dismal prognosis following their first relapse. Relapse can be attributed to the inability of chemotherapy agents to eradicate leukemia stem cells (LSC), which possess self-renewal capabilities and are responsible for the long-term maintenance of the disease. …”
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Signet Ring Cell Carcinoma of the Colon in Young Adults: A Case Report and Literature Review by Farida Abi Farraj, Hadi Sabbagh, Tarek Aridi, Najla Fakhruddin, Fadi Farhat

“…Signet ring cell carcinoma is one of the rare histopathologic subtypes of CRC; however, it is more prevalent in AYA patients than in older adults and presents with unconventional histologic characteristics, a distinct clinical behavior, and a poor prognosis. We report a case of a primary signet ring cell adenocarcinoma of the ascending colon in a 19-year-old male who presented with unusual signs and symptoms and was diagnosed with stage IVA (T4a N0 M1, with peritoneal seeding). …”
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Innovative applications of advanced nanomaterials in cerebrovascular imaging by Li Na, Xiaofu Song, Ping Luo, Jingqi Su, Zhicheng Yao

“…Cerebrovascular imaging is essential for the diagnosis, treatment, and prognosis of cerebrovascular disease, including stroke, aneurysms, and vascular malformations. …”
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Small Cell Carcinoma of the Larynx Treated by Concurrent Chemoradiotherapy: A Case Report by Susumu Nakahara, Norihiko Takemoto, Hidenori Inohara

“…In spite of intensive chemotherapy using CDDP and irinotecan (CPT-11), the patient died of disease in 34 months after the first interview. Since the prognosis of laryngeal SmCC is extremely poor, organ preservation therapy should be considered instead of radical laryngectomy.…”
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A Hybrid Oral Rehabilitation of Hypohidrotic Ectodermal Dysplasia: A Conservative Approach with Three-Year Follow-Up by Aryen Kaushik, HarshVardhan Sinha, M. N. Hombesh, Pooja Rani, Taranjeet Kaur

“…Atraumatic extraction of the teeth with hopeless prognosis was done, and teeth with grade 2 mobility were submerged using cast dowel and coping. …”
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Infected Baerveldt Glaucoma Drainage Device by Aspergillus niger by Nurul-Laila Salim, Yaakub Azhany, Zaidah Abdul Rahman, Roziawati Yusof, Ahmad Tajudin Liza-Sharmini

“…Management is challenging as the symptoms and signs may be subtle at initial presentation and the visual prognosis is usually poor due to its resistant nature to treatment. …”
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Hypoxemic Bronchiolitis Related to Major Histocompatibility Class II Deficiency by S. Hammami, H. Besbès, S. Hadded, K. Lajmi, L. Ghédira, Ch. B. Meriem, M. N. Guediche

“…Early diagnosis is essential due to high mortality in the first 2 years of life. Prognosis is very poor when bone marrow transplantation cannot be performed. …”
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Glioblastoma Circulating Cells: Reality, Trap or Illusion? by A. Lombard, N. Goffart, B. Rogister

“…Glioblastoma multiforme (GBM), the most frequent primary brain neoplasm, is mainly characterized by a dismal prognosis. The usual fatal issue for GBM patients is a consequence of local recurrence that is observed most of the time without any distant metastases. …”
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e-Health Tools for Targeting and Improving Melanoma Screening: A Review by Abhilasha Tyagi, Kimberly Miller, Myles Cockburn

“…The key to improved prognosis for melanoma is early detection and diagnosis, achieved by skin surveillance and secondary prevention (screening). …”
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Correlation analysis of recurrent factors in borderline ovarian tumors undergoing fertility preservation surgery by Yichi Xie, Dandan Wang, Ningning Zhang, Qing Yang

“…The results of multivariate analysis showed that the pathological features of micro papillary structure, intra operative as cites, bilateral tumors, and the increased ratio of neu tro phil to lymphocyte before surgery are independent risk factors for the recurrence of borderline ovarian tumors.ConclusionThe prognosis of women of childbearing age with borderline ovarian tumors undergoing conservation function surgery is good. …”
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Research progress on coronary slow flow or no-reflow of coronary heart disease undergoing percutaneous coronary intervention surgery by Mengdi Wang, Min Zeng

“…Coronary heart disease (CHD), a prevalent cardiovascular disorder, poses a significant threat to human health.Particularly, ST-segment elevation myocardial infarction (STEMI) is associated with a higher mortality rate.Timely and effective revascularization of the culprit vessels is crucial.Percutaneous coronary intervention (PCI) is a preferred and critical treatment modality for STEMI patients, effectively addressing vascular obstruction.However, a subset of patients experiences coronary slow flow (CSF) or no-reflow (NR) postoperatively, which severely impacts their prognosis.This article provides a comprehensive review of the definition, diagnosis, epidemiology, predictive factors, mechanisms, and treatment of CSF/NR, aiming to offer guidance for the clinical management of these complications following PCI in CHD patients.…”
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Biomarkers of traumatic brain injury. Literature review by A. Šmigelskytė, M. Remenčiūtė, V. Ragaišis

“…New biomarkers of TBI are being tested to avoid unnecessary head CT scans, diagnose TBI in a fast and efficient way, and determine its severity and prognosis. In the year of 2013, Scandinavian Neurotrauma Committee recommended S-100β for clinical use to predict intracranial injury on CT scans for suspected mild TBI. …”
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