A Rare Case of Primary Anterior Mediastinal Yolk Sac Tumor in an Elderly Adult Male by Sammy G. Nakhla, Srinath Sundararajan

“…Mediastinal germ cell tumors have a worse prognosis than gonadal germ cell tumors. Chemotherapy followed by adjuvant surgery improves overall response in EGGCTs. …”
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Palpable Penile Metastases: A Bizarre Presentation of Rectal Adenocarcinoma by Liza Cholin, Sarah Perz, Furman Mahmood, Saleem Zafar

“…A review of the literature indicates that corporeal metastasis as an initial presentation of malignancy is an extremely rare occurrence and carries a very poor prognosis.…”
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Pheochromocytoma Presenting as Acute Heart Failure Leading to Cardiogenic Shock and Multiorgan Failure by Jochen Steppan, Julia Shields, Ralph Lebron

“…Given the ample diagnostic tools and good prognosis when treated suitably, the diagnosis should be entertained early in patients, presenting with unexplained cardiovascular compromise.…”
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A Case of Rosai-Dorfman Disease Successfully Treated by Corticotherapy by Alioune Badara Diallo, Moustapha Ndiaye, Moussa Seck, Mohamed Keita, Elimane Seydi Bousso, Sokhna Aissatou Touré, Blaise Félix Faye, Saliou Diop

“…This observation illustrates the clinical presentation and diagnosis of this rare clinicopathological entity. The prognosis and treatment options are also discussed.…”
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Endoscopic resection of mucosa and dissection of submucosal layer at early stomach cancer by S. V. Kashin, R. O. Kuvayev, Ye. L. Zakrevskaya, D. V. Zav’yalov

“…Revealing of stomach cancer at early stages and adequate treatment of patients improve the prognosis. Screening diagnostics of the asymptomatic population and investigation of risk groups are efficient approaches in detection of early stomach cancer. …”
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Cardiac Involvement by HIV-Associated DLBCL by Charles T. Mupamombe, Jude Noel, Derek B. Laskar, Liza Valdivia

“…Of the different types of NHLs, diffuse large B-cell lymphoma (DLBCL) is the most common. Prognosis of DLBCL has improved over the years in the general population but remains relatively poor in HIV-positive individuals. …”
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A true malignant mixed tumour of the parotid gland by Ayesha McLennan-Dalal, Efstathia Kyrodimou, Sarah L. Saunders, Syed Ali Khurram, Andrew S. McLennan

“…Management is by means of radical surgery, but prognosis remains poor. We present a case of this rare tumour seen in a young patient to highlight its aggressive potential.…”
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Erythema Ab Igne due to Heating Pad Use: A Case Report and Review of Clinical Presentation, Prevention, and Complications by Marissa Milchak, Joanne Smucker, Catherine G. Chung, Elizabeth V. Seiverling

“…While this dermatosis carries a favorable prognosis, nonmelanoma skin cancers have been reported to arise within lesions of erythema ab igne. …”
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Dysphagia in patients with cerebrovascular disease. Update. by Amarilis Barbié Rubiera, Ligia María Marcos Plasencia, Yolanda Aguilera Martínez

“…An important number of patients with cerebrovascular disease also present dysphagia as a result of damage in cerebral hemispheres or brainstem, which contributes to negative morbility and functional rehabilitation prognosis due to the complications liked with this condition. …”
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Anesthetic Approach for a Patient with Jeune Syndrome by Mehmet I. Buget, Emine Ozkan, Ipek S. Edipoglu, Suleyman Kucukay

“…A narrow bell-shaped thoracic wall and short extremities are the most typical features of the syndrome. Prognosis in JS depends on the severity of the pulmonary hypoplasia caused by the chest wall deformity. …”
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Molecular Pathogenesis of Cholangiocarcinoma by G. Fava, I. Lorenzini

“…The principal concept that at least seems to be established is that cholangiocarcinogenesis is a multistep cellular process evolving from a normal condition of the epithelial biliary cells through a chronic inflammation status ending with malignant transformation. The bad prognosis related to CC justifies why a better identification of the molecular mechanisms involved in the growth and progression of this cancer is required for the development of effective preventive measures and valid treatment regimens. …”
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Mucinous rectal adenocarcinoma recurrence: A case report and literature review by Riya Sood, BS, Trisha Badjatia, Peeyush Bhargava, MD, MBA

“…Characterized by the presence of extracellular mucin constituting at least 50% of the tumor volume, MRA is associated with a poorer prognosis and more advanced tumor stage at presentation compared to nonmucinous rectal adenocarcinomas. …”
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Rhodotorula Endogenous Endophthalmitis: A Novel Harbinger of the Injection Drug Epidemic in the United States by Preston M. Luong, Basilio Kalpakian, Lawrence J. Jaeger, Timothy Lahey, Christopher B. Chapman, Michael E. Zegans

“…Worldwide experience with Rhodotorula endogenous endophthalmitis is limited, but existing cases suggest infection by this particular fungal genus has a grim prognosis.…”
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Biomarkers for Hepatocellular Carcinoma by Tara Behne, M. Sitki Copur

“…These markers not only help in prediction of prognosis or recurrence but may also assist in deciding appropriate modality of therapy and may represent novel potential targets for therapeutic interventions. …”
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Retinoid Therapy in a Case of Harlequin Ichthyosis with a Short Literature Review by Emad Bahashwan, Jaber Alfaifi, Sahar Elmaghawri Mohamed Moursi, Youssef Elbayoumi Soliman

“…After admitting him to the NICU, a multidisciplinary treatment approach was conducted with paediatric dermatologists, ophthalmologists, urologists, and dieticians. The prognosis is positive, with desquamation of the hyperkeratotic plate revealing an erythematous and shiny skin. …”
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Uveal Melanoma by Vasilios P. Papastefanou, Victoria M. L. Cohen

“…Development of metastases affects prognosis significantly. Current survival rates, factors predictive of metastatic potential and metastatic screening algorithms are discussed. …”
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No-Reflow Phenomenon and Endothelial Glycocalyx of Microcirculation by Alexander V. Maksimenko, Askar D. Turashev

“…The adjacent therapy is targeted on the damage of the microcirculation, leading to the unfavorable prognosis for the patients. The no-reflow phenomenon holds special place in the multifactorial etiology of the microcirculation disorders, offering a new challenge in treating the patients associated with ST-segment elevation on ECG at myocardial infarction. …”
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Open Questions in the Management of Nodular Lymphocyte Predominant Hodgkin Lymphoma by Marguerite Tyran, Laurence Gonzague, Reda Bouabdallah, Michel Resbeut

“…Localized Nodular Lymphocyte Predominant Hodgkin Lymphoma is a rare disease with an overall good prognosis but frequent late relapses. Due to it’s rarity there is no standard therapeutic approach and pathological diagnosis may be hard. …”
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The Surgical Treatment of Pelvic Bone Metastases by Daniel A. Müller, Rodolfo Capanna

“…Different reconstruction techniques for the pelvis are available; the choice depends on the patient’s prognosis, size of the bone defect, and response of the tumor to adjuvant treatment. …”
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A Case of Chyloperitoneum Secondary to Follicular Lymphoma and a Review of Prognostic Implications by Megan Jagosky, Brice Taylor, Stephanie Parks Taylor

“…Malignancy, specifically lymphoma, is reported to be the predominant cause in Western countries. Previously, the prognosis for patients with chyloperitoneum due to lymphoma has been reported as poor. …”
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