Immunosuppressive metabolites in tumoral immune evasion: redundancies, clinical efforts, and pathways forward by David Munn, Maria Rain Jennings, John Blazeck

“…Retrospective analyses of clinical data have elucidated that their activity is negatively associated with prognosis in diverse cancer indications, though there is a current paucity of approved therapies that disrupt their synthesis or downstream signaling axes. …”
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A Case of Amyopathic Dermatomyositis with Pneumomediastinum and Subcutaneous Emphysema by Aslıhan Gürün Kaya, Aydın Çiledağ, Orhan Küçükşahin, Özlem Özdemir Kumbasar, Çetin Atasoy

“…The patient presented with extremely rare occurrence of pneumomediastinum and subcutaneous emphysema in amyopathic dermatomyositis with a poor prognosis.…”
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A Rare Case of an Advanced Gastric Adenocarcinoma in a Teenage Syrian Boy by Baraa Daboul, Ahmad Ghazal, Ayham Al Halak, Sabah Hayed, Yasmin Najjar

“…In this report, we describe a case of a gastric cancer in young age group with delayed diagnosis and poor prognosis. We report a rare case of a 16-year-old teenager with an advanced moderately differentiated gastric adenocarcinoma without any relevant history. …”
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Oral and Lower Extremity Ulcers as the Initial Presentation of Granulomatosis with Polyangiitis by Mohammed Omar Al Salihi, Bianca Dominguez, Viresh Mohanlal, S. J. Carlan

“…It is typically a disease of white females and has a poor prognosis with the average life expectancy of 5 months for a patient without treatment. …”
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Maximizing the Survival of Amyotrophic Lateral Sclerosis Patients: Current Perspectives by Osama A. Khairoalsindi, Ahmad R. Abuzinadah

“…The disease has a poor prognosis, with only two disease-modifying drugs approved by the United States Food and Drug Administration (FDA). …”
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Twice Daily Prazosin and Valproic Acid in the Treatment of Flashbacks in PTSD by Kristy A. Fisher, Heidi Kiziah, Clara L. Villalba Alvarez

“…Further investigation is needed to expand upon our knowledge of the use of such agents in the treatment of PTSD to improve upon existing clinical guidelines, especially in the acute setting, thus providing better overall prognosis.…”
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Fracture of the Atlas through a Synchondrosis of Anterior Arch by Gamze Turk, Ismail M. Kabakus, Erhan Akpinar

“…In paediatric cases, most fractures occur through the synchondroses which are the weakest links of the atlas. The prognosis depends on the severity of the spinal cord injury. …”
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Plasmacytoid Urothelial Carcinoma of the Bladder That Manifests Disseminated Carcinomatosis of the Bone Marrow: A Case Report of Extremely Rapid Progression by Nobuhiko Shimizu, Yoshinobu Moritoki, Nao Katsumi, Takahiro Yanase, Teruaki Sugino, Kazuhiro Kanemoto, Hidetoshi Akita, Takahiro Yasui

“…Plasmacytoid urothelial carcinoma (PUC) of the bladder is a rare variant of invasive urothelial carcinoma (UC) with aggressive behavior. Despite its prognosis being poorer than that of conventional UC, a median overall survival of approximately 2 years is ensured when it is treated with radical cystectomy (RC), and few patients die within a few months of RC. …”
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Small Cell Lung Cancer with Positive Anti-Hu Antibodies Presenting as Gastroparesis by David N Moskovitz, Kenneth V Robb

“…SCLC commonly relapses, resulting in a 3% to 8% five-year survival rate. The poor prognosis associated with SCLC is partly due to late diagnosis of the disease. …”
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Endo-Perio Lesion and Uncontrolled Diabetes by Sara Dhoum, Kaoutar Laslami, Fatimazahraa Rouggani, Amal El Ouazzani, Mouna Jabri

“…This work is to discuss the management of an endo-perio lesion, which represents a challenge to clinicians when it comes to diagnosis and prognosis of the involved teeth and especially with an altered general condition. …”
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TERT promoter mutations in thyroid cancer by Michiko Matsuse, Norisato Mitsutake

“…In differentiated thyroid carcinoma, TERT-p mutations are associated with a number of high-risk clinicopathological aggressiveness and worse prognosis, making it the best molecular marker to predict tumor aggressiveness so far. …”
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Diagnostic and Prognostic Role of Procalcitonin in Infections by Maria Hatzistilianou

“…The problems with sepsis definitions and diagnoses are indications of the need to focus on biochemical mediators capable not only of distinguishing the inflammatory response to infection from other types of inflammation, but also of indicating the severity and prognosis of the disease. Thus, physicians need an early and rapid marker for detecting bacterial infection and distinguishing it from viral infection. …”
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Osteosarcoma of the Mandible Masquerading as a Dental Abscess: Report of a Case by Sukumaran Anil, Anitha P. Krishnan, R. Rajendran

“…The case report is followed by a brief review of osteosarcoma of the jaw with a note on its clinical presentation, diverse radiologic appearance, varied histopathologic picture, and prognosis.…”
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Pediatric optic neuritis: literature review by S. Bubnytė, J. Andrulionytė

“…The aim of this article is to review the symptoms, etiology, pathogenesis, diagnosis, treatment options, and prognosis of pediatric optic neuritis described in the literature. …”
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Current Concepts of Fracture-Related Infection by Si-ying He, Bin Yu, Nan Jiang

“…Therefore, early diagnosis and reasonable treatment are the key issues for increasing the cure rate, decreasing the risks of infection relapse and disability, and improving the life quality and prognosis of the patients. In this review, we summarized the present concepts regarding the definition, epidemiology, diagnosis, and treatment of FRI.…”
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Gold Price Forecasting: A Novel Approach Based on Text Mining and Big-Data-Driven Model by Poor Saeed Kian, Fattahi Shahram, Hajian Mohsen

“…To explain the gold price prognosis, the convolutional neural network (CNN) also uses linguistic criteria for news items about gold. …”
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Subsequent Development of Desmoid Tumor after a Resected Gastrointestinal Stromal Tumor by Areen Abdulelah Murshid, Hatim Q. Al-Maghraby

“…We discuss the two entities of Desmoid tumor and GIST by comparing their definitions, clinical presentations, histological features, immunohistochemistry stains, molecular pathogenesis, prognosis, and treatment. We also discuss the relationship between GIST and the subsequent development of Desmoid tumors and compare our case with case reports in literature.…”
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Clinical Resolution of Osmotic Demyelination Syndrome following Overcorrection of Severe Hyponatremia by Ruhin Yuridullah, Vinod Kumar, Sushant Nanavati, Monisha Singhal, Chandra Chandran

“…There is some controversy in the literature regarding the prognosis of these patients. Our aim here is to show that, with aggressive therapy and long-term care, recovery is possible in these patients.…”
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Development of Action and the Clinical Continuum by Brian Hopkins

“…., early detection, diagnosis, prognosis, and intervention). Illustrative examples germane to this approach are given with regard to how posture serves as a constraint on the emergence of reaching movements and how cortical development influences the coordination of leg movements as revealed by a study involving infants with white matter lesions. …”
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Small Cell Neuroendocrine Carcinoma of the Cervix in Pregnancy: A Case Report and Review by Linglan Pan, Renyan Liu, Xiujie Sheng, Dunjin Chen

“…We reviewed and discussed the features, diagnosis, and prognosis of small cell neuroendocrine carcinoma of the cervix.…”
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