Cerebrospinal fluid and serum cytokine profiles in severe viral encephalitis with implications for refractory status epilepticus: a retrospective observational study by Peipei Huang, Fan Yang, Ruirui Dong, Lijun Wen, Qiuling Zang, Dandan Song, Junshuang Guo, Yating Wang, Ruike Zhang, Zhiping Ren, Jinjin Qin, Junfang Teng, Wang Miao

“…During the early stage of SVE, CSF interleukin (IL)-6 and IL-8 levels were significantly higher, declining over time and affecting the prognosis. CSF IL-6 and IL-8 levels were significantly elevated in the RSE group compared to patients without seizures and with controlled seizures, decreasing gradually and independently of serum cytokine levels. …”
Get full text

Dysregulated Expression and Methylation Analysis Identified TLX1NB as a Novel Recurrence Marker in Low-Grade Gliomas by Hongzhou Duan, Zuozhen Yang, Chen Li, Jiayong Zhang, Shengli Shen, Changwei Yuan, Yingjin Wang

“…Biomarkers play a crucial role in evaluating the recurrence and prognosis of LGGs. Numerous studies have focused on LGG prognosis. …”
Get full text

Dual-positive gastric cancer: an extremely malignant subtype of gastric cancer with high serum alpha-fetoprotein and carcinoembryonic antigen concentrations by Weixun Xie, Chengyu Hu, Hongming Liu, Zelai Wu, Bixian Luo, Xiaoying Wu, Xiaoying Wu, Chuanlei Tuo, Ziyin Deng, Han Liang, Yong Liu, Weihua Gong, Weihua Gong

“…This study seeks to evaluate whether combining multiple tumor markers can enhance risk stratification and identify AFPGC subtypes with poor prognosis.MethodsWe first screened for patients with elevated serum CEA levels within the AFPGC cohort and evaluated their prognosis. …”
Get full text

Optimal Treatment for Intermediate- and High-Risk, Nonmuscle-Invasive Bladder Cancer by A.P.M. van der Meijden

“…According to clinical and pathological factors the prognosis of a patient with non-muscle invasive bladder tumors can be assessed. …”
Get full text

gas-forming pyomyositis in an immunocompetent patient: a case report and review by Jee Young Lee, Gyu Min Kong

“…The primary etiology of pyomyositis is predominantly Staphylococcus aureus , although Gram-negative bacteria may also be involved on rare occasions. The prognosis for pyomyositis caused by Gram-negative bacteria is more unfavorable than that of infections caused by Staphylococcus aureus. …”
Get full text

Concurrent Hairy Cell Leukemia and Metastatic Merkel Cell Carcinoma by Ajay Prakash, Alhossain A. Khalafallah

“…HCL has a favorable prognosis with most patients achieving long-term remission and potential cure. …”
Get full text

Elucidating the Correlation of D-Dimer Levels with COVID-19 Severity: A Scoping Review by Wesam Ahmed Nasif, Abeer Shaker El-Moursy Ali, Mohammed Hasan Mukhtar, Aali Marzouq H. Alhuzali, Yahya Ahmed Yahya Alnashri, Ziyad Ishaq Ahmed Gadah, Eyyad Adeeb A. Edrees, Hussam Abdulaziz Mabruk Albarakati, Hussam Saud Muhji Aloufi

“…The review explores the findings of previous studies to elucidate the association between levels of D-dimer and COVID-19 severity and prognosis. In addition, we assessed the efficiency of anticoagulant therapies in reducing COVID-19 severity and improving the prognosis of the patients. …”
Get full text

Systemic inflammatory response index improves prognostic predictive value in intensive care unit patients with sepsis by Tuo Xu, Shuaiwei Song, Ke Zhu, Yin Yang, Chengyu Wu, Naixue Wang, Shu Lu

“…The RCS curve demonstrated that the risk of poor prognosis rose with increasing SIRI, particularly when SIRI exceeded 6.1. …”
Get full text

The Significance of Serum CA-125 Elevation in Chinese Patients with Primary Budd-Chiari Syndrome: A Multicenter Study by De-lei Cheng, Hao Xu, Wei-fu Lv, Rong Hua, Hongtao Du, Qing-qiao Zhang

“…Serum CA-125 was significantly higher in patients with primary BCS and had a positive correlation with the volume of ascites, severity of liver damage, and poor prognosis. Thus the serum CA-125 levels may be used to estimate the severity and prognosis of BCS in Chinese patients.…”
Get full text

FHL1 as a prognostic biomarker and therapeutic target in acute promyelocytic leukaemia by Bo Luo, Wei Li, Jingyuan Zeng, Yingyu Mao, Shuang He, Nan Hu, Qulian Guo, Xiaoli Zheng

“…Abstract Acute myeloid leukemia (AML) has a poor prognosis and high heterogeneity. Most cases of leukemias are caused by environmental factors interacting with the cell’s genetic material, but treatment is still dominated by cell cycle drugs. …”
Get full text

TNM-Like Classification: A New Proposed Method for Heart Failure Staging by Francesco Fedele, Maria Chiara Gatto, Alessandra D’Ambrosi, Massimo Mancone

“…The typology of HF and the duration determine which organs will be affected and vice versa the severity of organ damage supplies precious information about prognosis and outcome of patients with heart failure. …”
Get full text

BPI-ANCA Provides Additional Clinical Information to Anti-Pseudomonas Serology: Results from a Cohort of 117 Swedish Cystic Fibrosis Patients by Ulrika Lindberg, Malin Carlsson, Thomas Hellmark, Mårten Segelmark

“…Patients with cystic fibrosis (CF) colonized with Pseudomonas aeruginosa (P. aeruginosa) have worse prognosis compared with patients who are not. BPI-ANCA is an anti-neutrophil cytoplasmic antibody against BPI (bactericidal/permeability increasing protein) correlating with P. aeruginosa colonization and adverse long time prognosis. …”
Get full text

Prognostic and Diagnostic Significance of circRNA Expression in Esophageal Cancer: A Meta-analysis by Hong Lin, Jinpeng Yuan, Guoxi Liang, Yanxuan Wu, Liming Chen

“…Conclusion. circRNAs might be a promising biomarker for diagnosis, prognosis, and clinicopathological features of EC.…”
Get full text

Mining Prognostic Biomarkers of Thyroid Cancer Patients Based on the Immune-Related Genes and Development of a Reliable Prognostic Risk Model by Hongjun Fei, Xu Han, Yanlin Wang, Shuyuan Li

“…Wilcox test was used to screen the differentially expressed immune-related genes (DEIRGs) in THCA and normal tissues, then the DEIRGs related to prognosis were identified using univariate Cox regression analysis. …”
Get full text

Correlation between Galectin-3 and Adverse Outcomes in Myocardial Infarction Patients: A Meta-Analysis by Lei Tian, Kan Chen, Zhihua Han

“…Some new biomarkers can help us to improve the life quality and prognosis of AMI patients. Objective. We therefore performed a systematic review and meta-analysis on the use of galectin-3 (gal3) for assessing prognosis of AMI patients. …”
Get full text

Longitudinal Change in Peripheral Anterior Chamber Depth of Eyes with Angle Closure after Laser Iridotomy by Toshie Furuya, Kenji Kashiwagi

“…The type of angle closure and some factors may be related to glaucoma prognosis after LI.…”
Get full text

Progress in the application of novel inflammatory indicators in chronic kidney disease by Wenrui Gao, Wenrui Gao, Xiangyu Wang, Xiangyu Wang, Yulin Zou, Sheng Wang, Jun Dou, Senlin Qian

“…Intervening in chronic inflammation during the disease course can enhance prognosis. Recent studies have demonstrated that novel inflammatory indices, such as the neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and systemic immune-inflammatory index are closely associated with CKD, meanwhile may serve as prognostic monitors of all-cause death and poor renal prognosis for the disease. …”
Get full text

Prognostic Roles of Inflammatory Markers in Pancreatic Cancer: Comparison between the Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio by Dongwook Oh, Jung-Soo Pyo, Byoung Kwan Son

“…Taken together, our results showed that inflammatory markers are useful for predicting prognosis in patients with pancreatic cancer. The NLR is a more suitable parameter for predicting prognosis regardless of the patient’s condition.…”
Get full text

Association of β-Catenin, APC, SMAD3/4, Tp53, and Cyclin D1 Genes in Colorectal Cancer: A Systematic Review and Meta-Analysis by Hongfeng Yan, Fuquan Jiang, Jianwu Yang

“…The present meta-analysis indicates that overexpression or underexpression and variants of CTNNB1/β-catenin, APC, SMAD3/4, TP53, and Cyclin D1 genes potentially acted as unfavorable biomarkers for the prognosis of CRC. The Wnt gene was not associated with prognosis.…”
Get full text

Exploration of the Long Noncoding RNAs Involved in the Crosstalk between M2 Macrophages and Tumor Metabolism in Lung Cancer by Fang Fang, Yuanshan Yao, Zhe Ma

“…Then, 67 lncRNAs involved in both M2 macrophages and related metabolism pathways were identified. A prognosis signature based on AC027288.3, AP001189.3, FAM30A, GAPLINC, LINC00578, and LINC01936 was established, which had good prognosis prediction ability. …”
Get full text