Invasive aspergillosis in critically ill patients with diabetes mellitus: a systematic review and meta-analysis by Yuhua Liu, Zhaopei Zhang, Liang Zhou, Tianlai Lin, Rong Zhang, Manshu Li, Sihao Chen, Xiaoqing Liu, Xuesong Liu

“…Abstract Background In the intensive care unit (ICU), invasive aspergillosis (IA) has a poor prognosis. Some studies report a positive association between diabetes mellitus (DM) and IA in critically ill patients, but the relationship between DM and IA in the ICU remains controversial. …”
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The Effects of Oral Semaglutide on Hepatic Fibrosis in Subjects with Type 2 Diabetes in Real-World Clinical Practice: A Post Hoc Analysis of the Sapporo-Oral SEMA Study by Hiroya Kitsunai, Yuka Shinozaki, Sho Furusawa, Naoyuki Kitao, Miki Ito, Hiroyoshi Kurihara, Chiho Oba-Yamamoto, Jun Takeuchi, Akinobu Nakamura, Yumi Takiyama, Hiroshi Nomoto

“…Background/Objectives: Metabolic dysfunction-associated steatotic liver disease (MASLD) is an important common comorbidity in subjects with type 2 diabetes, and liver fibrosis is a factor directly related to its prognosis. Glucagon-like peptide-1 receptor agonists are useful treatment options for MASLD; however, the efficacy of oral semaglutide in treating liver steatosis/fibrosis has not been fully elucidated. …”
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Alcohol abuse in gastroenterological patients by M. V. Mayevskaya, I. G. Bakulin, A. A. Chirkov, Ye. O. Lyusina, V. D. Lun’Kov

“…Physicians need to apply screening questionnaires of AUDIT-C and CAGE in their activity, encourage patients to decrease or completely stop alcohol intake, monitor and provide support to patients with alcohol abuse, initiate anti-alcoholic therapy in the cooperation with narcologists that will improve prognosis and decrease mortality from alcohol-related diseases.…”
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Prevalence and Molecular Characterization of Carbapenemase-Producing Multidrug-Resistant Bacteria in Diabetic Foot Ulcer Infections by Mohd Saleem, Soha Abdallah Moursi, Tahani Nasser Almofeed Altamimi, Mohammed Salem Alharbi, Alwaleed Mohammad Alaskar, Sahar Adly Hassan Hammam, Ehab Rakha, Ozair Ilyas Syed Muhammad, Hamoud Abdulmohsin Almalaq, Metab Nasser Alshammari, Azharuddin Sajid Syed Khaja

“…The increasing incidence of multidrug-resistant (MDR) bacteria in DFUs complicates treatment strategies and worsens patient prognosis. Among these pathogens, carbapenemase-producing pathogens have emerged as particularly concerning owing to their resistance to β-lactam antibiotics, including carbapenems. …”
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Efficacy and cost-effectiveness of an ACT and compassion-based intervention for women with breast cancer: study protocol of two randomised controlled trials {1} by Inês A. Trindade, Andreia Soares, David Skvarc, Diogo Carreiras, Joana Pereira, Óscar Lourenço, Filipa Sampaio, Bruno de Sousa, Teresa C. Martins, Paula Boaventura, Joana Marta-Simões, Mind Project Team, Helena Moreira

“…Study 1 will also include immunological and epigenetic markers associated with breast cancer prognosis and mental health. Outcome assessors will be blind to group allocation. …”
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Single-cell profiling of SLC family transporters: uncovering the role of SLC7A1 in osteosarcoma by Yan Liao, Junkai Chen, Hao Yao, Ting Zheng, Jian Tu, Weidong Chen, ZeHao Guo, Yutong Zou, Lili Wen, Xianbiao Xie

“…In vitro assays and survival analysis demonstrated that inhibition of SLC7A1 suppressed the malignant phenotype of osteosarcoma cells, with SLC7A1 expression correlating with poor prognosis. Co-culture models confirmed the involvement of SLC7A1 in macrophage polarization. …”
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New clinical insights into the treatment of benign uretero‐ileal anastomotic stricture following radical cystectomy and urinary diversion by Yixuan Mou, Cenchao Yao, Zhenghong Liu, Pu Zhang, Xiaolong Qi, Dahong Zhang, Yiyang Chen, Weiwen Yu, Shuai Wang

“…To preserve residual renal function and improve prognosis, it is crucial to derive insights from experience and tailor individualized treatment strategies for different patients. …”
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Genetic Polymorphism and Expression of CXCR4 in Breast Cancer by Marina Okuyama Kishima, Karen Brajão de Oliveira, Carolina Batista Ariza, Carlos Eduardo Coral de Oliveira, Roberta Losi Guembarovski, Bruna Karina Banin Hirata, Felipe Campos de Almeida, Glauco Akelinghton Freire Vitiello, Kleber Paiva Trugilo, Alda Fiorina Maria Losi Guembarovski, Walter Jorge Sobrinho, Clodoaldo Zago Campos, Maria Angelica Ehara Watanabe

“…CXCR4 genetic polymorphisms, as well as their expression level, have been associated with cancer development and prognosis. The present study aimed to investigate the influence of CXCR4 rs2228014 polymorphism on its mRNA and protein expression in breast cancer samples. …”
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The clinical prediction model to distinguish between colonization and infection by Klebsiella pneumoniae by Xiaoyu Zhang, Xifan Zhang, Deng Zhang, Jing Xu, Jingping Zhang, Xin Zhang

“…In the future, the accuracy of infection diagnosis can be further enhanced through artificial intelligence technology to optimize treatment strategies, thereby improving patient prognosis and reducing healthcare burdens.…”
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Functional interaction between receptor tyrosine kinase MET and ETS transcription factors promotes prostate cancer progression by Elisa Carouge, Clémence Burnichon, Martin Figeac, Shéhérazade Sebda, Nathalie Vanpouille, Audrey Vinchent, Marie‐José Truong, Martine Duterque‐Coquillaud, David Tulasne, Anne Chotteau‐Lelièvre

“…Prostate cancer, the most common malignancy in men, has a relatively favourable prognosis. However, when it spreads to the bone, the survival rate drops dramatically. …”
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Modulation of DAPK1 expression by its alternative splice variant DAPK1-215 in cancer by QingShui Wang, ShuYun Weng, WenTing Zhong, YouYu Lin, Yan Yu, YiMin Huang, LiLin Ge, XiuLi Zhang, FangQin Xue, Yehuda G. Assaraf, Yao Lin

“…Importantly, high levels of DAPK1-215 correlated inversely with DAPK1 mRNA in liver cancer specimens and predicted poor prognosis, whereas high DAPK1 expression predicted improved patient outcomes. …”
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Risk factors and renal outcomes of AKI in children with secondary steroid-resistant nephrotic syndrome by Nannan Yu, XiaoJun Ouyang, Jie Li, Jie Gao, Shuhan Zeng, Hongjie Zhuang, Mengjie Jiang, Yuxin Pei, Xiaoyun Jiang

“…The main objectives of this study were to determine the risk factors and prognosis of AKI in hospitalized children with secondary SRNS.Material and methods This retrospective study was conducted from January 2014 to December 2019, involving 172 hospitalizations with secondary SRNS admitted to the First Affiliated Hospital of Sun Yat-sen University. …”
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Mfsd2a suppresses colorectal cancer progression and liver metastasis via the S100A14/STAT3 axis by Linfeng Sun, Xiangdong Li, Yuhao Xiao, Wenjie Yu, Xuyang Chen, Ziyi Wang, Nan Xia, Xuejiao Chen, Minhao Chen, Haoliang Zhu, Jie Li, Jie Wei, Sheng Han, Liyong Pu

“…Results We observed that Mfsd2a expression is reduced in LM compared to PT, and higher Mfsd2a levels are associated with better prognosis in CRLM patients. Furthermore, function assays demonstrated that Mfsd2a suppresses CRC cells proliferation, migration, invasion, and EMT in vitro, while also delaying tumor growth and liver metastasis in vivo. …”
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Oncometabolite D-2HG drives tumor metastasis and protumoral macrophage polarization by targeting FTO/m6A/ANGPTL4/integrin axis in triple-negative breast cancer by Siyue Zhang, Ning Zhang, Tong Wan, Yinqiao He, Jie Hao, Yiwei Liu, Yidong Liu, Bing Chen, Wenjing Zhao, Lijuan Wang, Dan Luo, Chao Gao, Qifeng Yang

“…The association of ANGPTL4 with poor prognosis in TNBC patients underscores its clinical relevance. …”
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Assessment of the influence of gap wall mobility factor at calculation of leakage in working section of a scroll compressor. Part 1 by V. A. Pronin, A. V. Kovanov, V. A. Tsvetkov, E. N. Mikhailova, E. A. Kalashnikova

“…It will raise accuracy of the received results which can serve as a base to prognosis of optimum characteristics of the compressor, due to their approximation and will allow to optimize designing of refrigerating machines at the chosen modes of work. …”
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Deciphering the Differences Between Epstein–Barr Virus‐Associated and Negative Gastric Cancer in the Prospect of CDKN2A Genomic Alterations and Lymphoid Infiltration by Fuda Xie, Bonan Chen, Yang Lyu, Peiyao Yu, Canbin Fang, Kam Tong Leung, Shouyu Wang, Dazhi Xu, Jun Yu, Kwok Wai Lo, Ka Fai To, Wei Kang

“…Furthermore, EBV infection was positively correlated with CD8+T cell infiltration, and both of them predicted better prognosis. Conclusion This study highlighted the comprehensive impact of EBV infection in GC formation and proposed a thought‐provoking observation for further investigation into the roles of CDKN2A and EBV infection in gastric tumorigenesis.…”
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Machine learning-based identification and validation of amino acid metabolism related genes as novel biomarkers in chronic kidney disease by Guoqing Zhang, Hongyan Luo, Xiaohua Lu, Yonghua Liu, Mei Wang, Bo Li, Haixia Lu, Yali Zheng

“…Conclusions: Our study identified key genes involved in amino acid metabolism associated with immune cells infiltration and renal function in CKD, which may be potential biomarkers for the diagnosis and prognosis of CKD.…”
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Expression pattern of lncRNA H19 in oral squamous cell carcinoma tissues in comparison to normal tissues. A systematic review by Ramya Sekar, Selvaraj Jayaraman, Saranya Varadarajan, Thodur Madapusi Balaji, Vishnupriya Veeraraghavan, Prabhu Shankar Dayasankar, Dharshini Devi J

“…The necessity for trustworthy biomarkers is highlighted by the fact that early diagnosis and prognosis are still difficult despite advancements. …”
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The multidisciplinary approach to the treatment of paediatric chronic pain: a qualitative analysis through focus groups by Aldana Paola Ercolano, Sabrina Galvan, Tessa Louise Marchesan, Alessia Gavioli, Gerardo Papa, Mariarita Todaro, Lidia Berforini D’Aquino, Alessia Zanatta, Andrea Vianello

“…It becomes chronic when it persists beyond three months, affecting quality of life and clinical prognosis. The World Health Organization (WHO) has recently promoted a multidisciplinary approach for pediatric chronic pain, integrating physical, psychological, and pharmacological interventions, given the high prevalence of pain in pediatric populations, affecting up to 46% of children and adolescents. …”
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Circulating tumor DNA for surveillance in high-risk melanoma patients: a study protocol by Magnús P.B. Obinah, Sarah A. Al-Halafi, Karin Dreisig, Tim S. Poulsen, Christoffer Johansen, Thomas Litman, Stig E. Bojesen, Estrid Høgdall, Annette H. Chakera, Lisbet R. Hölmich

“…The aim is to overcome the limitations of current methods, potentially improving prognosis and survival. Patients/material and methods: Patients with high risk of recurrence following primary treatment of melanoma are offered inclusion. …”
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