Temporal Trends in Mortality and Hospitalization Risk in Patients With Heart Failure According to the Hospital Frailty Risk Score by Noor K. Abassi, Nina Nouhravesh, Mariam Elmegaard, Marte Austreim, Deewa Zahir, Caroline Hartwell Garred, Jawad H. Butt, Camilla Fuchs Andersen, Jarl E. Strange, Caroline Sindet‐Pedersen, Daniel M. Christensen, Emil Fosbøl, Charlotte Andersson, Lars Køber, Morten Schou

“…However, it is unknown how the interplay between HF and frailty at HF onset impacts prognosis of frail patients with HF and how this has evolved over time. …”
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Electrocardiography-based artificial intelligence predicts the upcoming future of heart failure with mildly reduced ejection fraction by Dae-Young Kim, Sang-Won Lee, Dong-Ho Lee, Sang-Chul Lee, Sang-Chul Lee, Ji-Hun Jang, Sung-Hee Shin, Dae-Hyeok Kim, Dae-Hyeok Kim, Wonik Choi, Wonik Choi, Yong-Soo Baek, Yong-Soo Baek, Yong-Soo Baek

“…This study aimed to develop artificial intelligence (AI)-electrocardiography (ECG) to identify and predict the prognosis of patients with HFmrEF.MethodsWe collected 104,336 12-lead ECG datasets from April 2009 to December 2021 in a tertiary centre. …”
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Difficultés diagnostiques de la tuberculose cérébrale by Chahrazed Benrabah

“…The diagnosis is postoperative, based on the pathological examination. The prognosis depends on the early diagnosis, the site of the lesion and the response to anti-tuberculosis treatment. …”
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Molecular characterization of pregnancy-associated breast cancer and insights on timing from GEICAM-EMBARCAM study by Regina Peña-Enríquez, Begoña Bermejo, Marina Pollán, Alejandra Díaz-Chacón, Yolanda Jerez Gilarranz, José J Ponce Lorenzo, Antonio Fernández Aramburo, Blanca Cantos Sánchez de Ibargüen, Ana Santaballa Bertrán, Elena Galve-Calvo, Álvaro Jiménez-Arranz, Yolanda Fernández, María Eva Pérez, Susana De La Cruz, Antonio Anton-Torres, Fernando Moreno, María Jesús Vidal-Losada, María Helena López-Ceballos, Isabel Blancas, María José Echarri, Raúl Rincón, Rosalía Caballero, Ángel Guerrero-Zotano, Silvia Guil-Luna, Juan de la Haba-Rodríguez

“…Abstract Pregnancy-associated breast cancer (PABC), diagnosed during or shortly after pregnancy, is a challenging entity with an aggressive biology and poor prognosis. This study analyzed the clinicopathological characteristics and gene expression profile of 33 PABC and 26 non-PABC patients using the nCounter BC360 Panel (NanoString). …”
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Difficultés diagnostiques de la tuberculose cérébrale by Chahrazed Benrabah

“…The diagnosis is postoperative, based on the pathological examination. The prognosis depends on the early diagnosis, the site of the lesion and the response to anti-tuberculosis treatment. …”
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Potential of 6-mm-diameter fully covered self-expandable metal stents for unresectable malignant distal biliary obstruction: a propensity score-matched study by Daiki Yamashige, Susumu Hijioka, Yoshikuni Nagashio, Yuta Maruki, Soma Fukuda, Shin Yagi, Kohei Okamoto, Hidenobu Hara, Yuya Hagiwara, Daiki Agarie, Tetsuro Takasaki, Akihiro Ohba, Shunsuke Kondo, Chigusa Morizane, Hideki Ueno, Miyuki Sone, Yutaka Saito, Takuji Okusaka

“…Conclusions For UR-MDBO, a 6-mm-diameter FCSEMS can be an optimal and safe option in the younger cohort with a relatively high risk of AEs and in the end-stage cohort requiring safer drainage without interference from stent-related events during times of poor prognosis.…”
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Radiogenomics and machine learning predict oncogenic signaling pathways in glioblastoma by Abdul Basit Ahanger, Syed Wajid Aalam, Tariq Ahmad Masoodi, Asma Shah, Meraj Alam Khan, Ajaz A. Bhat, Assif Assad, Muzafar Ahmad Macha, Muzafar Rasool Bhat

“…Abstract Background Glioblastoma (GBM) is a highly aggressive brain tumor associated with a poor patient prognosis. The survival rate remains low despite standard therapies, highlighting the urgent need for novel treatment strategies. …”
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Hubungan Jumlah Trombosit, Hematokrit dan Hemoglobin dengan Derajat Klinik Demam Berdarah Dengue pada Pasien Dewasa di RSUP. M. Djamil Padang by Yobi Syumarta, Akmal M. Hanif, Erlina Rustam

“…</p><p>Abstract<br />Prompt diagnosis and as an accurate assessment of the stage and condition of DHF cases is a very important factor for determining patient prognosis. The existence of an exact value of the results of platelets, hematocrit, and hemoglobin for each grade of DHF are expected to greatly assist in classify and manage patients based on the clinical degree. …”
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Early-Stage Luminal B-like Breast Cancer Exhibits a More Immunosuppressive Tumor Microenvironment than Luminal A-like Breast Cancer by Tânia Moura, Olga Caramelo, Isabel Silva, Sandra Silva, Manuela Gonçalo, Maria Antónia Portilha, João N. Moreira, Ana M. Gil, Paula Laranjeira, Artur Paiva

“…Background: Breast cancer is a heterogeneous malignant disease with a varying prognosis and is classified into four molecular subtypes. …”
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Human placental extract improves liver cirrhosis in mice with regulation of macrophages and senescent cells by Natsuki Ishikawa, Yusuke Watanabe, Yuichirou Maeda, Tomoaki Yoshida, Naruhiro Kimura, Hiroyuki Abe, Akira Sakamaki, Hiroteru Kamimura, Takeshi Yokoo, Kenya Kamimura, Atsunori Tsuchiya, Shuji Terai

“…Introduction: Cirrhosis is a disease with poor prognosis that requires the development of a novel therapeutic approach alternative to liver transplantation. …”
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Long‐term survival outcome with tyrosine kinase inhibitors and surgical intervention in patients with metastatic or recurrent gastrointestinal stromal tumors: A 14‐year, single‐cen... by Jwa Hoon Kim, Min‐Hee Ryu, Changhoon Yoo, Heejung Chae, Hana Na, Moyoul Beck, Beom Su Kim, Moon‐Won Yoo, Jeong Hwan Yook, Byung Sik Kim, Ki‐Hun Kim, Chan Wook Kim, Yoon‐Koo Kang

“…Patients with advanced GIST showed better prognosis with the optimal use of imatinib, along with active surgical intervention and more common use of subsequent TKIs in period 2.…”
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CASC8 activates the pentose phosphate pathway to inhibit disulfidptosis in pancreatic ductal adenocarcinoma though the c-Myc-GLUT1 axis by Hong-Fei Yao, Jieqiong Ge, Jiahao Chen, Xiaoyan Tang, Chunjing Li, Xiao Hu, Abousalam Abdoulkader Ahmed, Yunlong Pu, Guihua Zhou, Tongyi Zhang, Zhiwei Cai, Chongyi Jiang

“…High CASC8 expression correlated with a poor prognosis for patients with PDAC and contributed to cancer progression in vitro and in vivo. …”
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Changes in Phenylacetylglutamine Levels Provide Add-On Value in Risk Stratification of Hypertensive Patients: A Longitudinal Cohort Study by Xuan Xu, Lixin Jia, Bokang Qiao, Yanyan Gong, Shan Gao, Yuan Wang, Jie Du

“…PAGln should be considered as an independent predictor in risk stratification to improve prognosis.…”
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AI-Based Advanced Approaches and Dry Eye Disease Detection Based on Multi-Source Evidence: Cases, Applications, Issues, and Future Directions by Mini Han Wang, Lumin Xing, Yi Pan, Feng Gu, Junbin Fang, Xiangrong Yu, Chi Pui Pang, Kelvin Kam-Lung Chong, Carol Yim-Lui Cheung, Xulin Liao, Xiaoxiao Fang, Jie Yang, Ruoyu Zhou, Xiaoshu Zhou, Fengling Wang, Wenjian Liu

“…This study explores the potential of Artificial Intelligence (AI) in early screening and prognosis of Dry Eye Disease (DED), aiming to enhance the accuracy of therapeutic approaches for eye-care practitioners. …”
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Acute Kidney Injury after Major Abdominal Surgery: A Retrospective Cohort Analysis by Catarina Teixeira, Rosário Rosa, Natacha Rodrigues, Inês Mendes, Lígia Peixoto, Sofia Dias, Maria João Melo, Marta Pereira, Henrique Bicha Castelo, José António Lopes

“…We analyzed the incidence, risk factors, and prognosis of acute kidney injury (AKI) in a cohort of patients undergoing major abdominal surgery. …”
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Clinical impact of proteinuria on renal function and treatment outcomes in patients with radioiodine-refractory thyroid cancer treated with lenvatinib by Naoki Fukuda, Kazuhisa Toda, Hirotaka Suto, Ryosuke Oki, Xiaofei Wang, Tetsuya Urasaki, Yasuyoshi Sato, Kenji Nakano, Makiko Ono, Junichi Tomomatsu, Hiroki Mitani, Shunji Takahashi

“…We conducted a retrospective observational study to assess renal function and prognosis in patients with radioiodine-refractory differentiated thyroid cancer (RR-DTC) receiving lenvatinib. …”
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Analysis of Risk Factors of Gastric Low-Grade Intraepithelial Neoplasia in Asymptomatic Subjects Undergoing Physical Examination by Yingling Liu, Yuli Cai, Si Chen, Yawen Gou, Qiaomin Wang, Mingli Zhang, Yetao Wang, Haiou Hong, Kaiguang Zhang

“…Risk factors were evaluated, and the endoscopic features of LGIN and prognosis were described. The overall incidence of LGIN was 19.73% (678/3437), while the incidence of LGIN in the asymptomatic and symptomatic groups was 19.65% (444/2259) and 19.86% (234/1178), respectively (P=0.884). …”
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Green sanctuaries: residential green and garden space and the natural environment mitigate mental disorders risk of diabetic patients by Erxu Xue, Jianhui Zhao, Jingyu Ye, Jingjie Wu, Dandan Chen, Jing Shao, Xue Li, Zhihong Ye

“…Abstract Background The co-occurrence of diabetes and mental disorders is an exceedingly common comorbidity with poor prognosis. We aim to investigate the impact of green space, garden space, and the natural environment on the risk of mental disorders among the population living with diabetes. …”
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Immunosuppression and Outcomes in Patients with Cutaneous Squamous Cell Carcinoma of the Head and Neck by Doriana Iancu, Ana Fulga, Doina Vesa, Iuliu Fulga, Dana Tutunaru, Andrei Zenovia, Alin Ionut Piraianu, Elena Stamate, Corina Sterian, Florentin Dimofte, Mihail Alexandru Badea, Alin Laurentiu Tatu

“…The role of immune status is not yet determined in the prognosis of these patients. <b>Objective</b>. Immunosuppressed patients are more likely to develop cSCC, which is often characterized by more aggressive, multifocal lesions. …”
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Gastroblastoma in Adulthood—A Rarity among Rare Cancers—A Case Report and Review of the Literature by Giovanni Centonze, Alessandro Mangogna, Tiziana Salviato, Beatrice Belmonte, Laura Cattaneo, Melissa Anna Teresa Monica, Giovanna Garzone, Cecilia Brambilla, Alessio Pellegrinelli, Flavia Melotti, Adele Testi, Valentina Monti, Ketevani Kankava, Patrizia Gasparini, Gianpaolo Dagrada, Vincenzo Mazzaferro, Christian Cotsoglou, Paola Collini, Giancarlo Pruneri, Massimo Milione

“…Hence, GB should be considered in the differential diagnosis of microscopically comparable conditions in adults carrying a worse prognosis and different clinical approach.…”
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