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3281
Expanding diversity in developmental profiles of very-low-birth-weight infants during 6 years after birth
Published 2025-02-01“…Clustering analyses indicated that DQ values at age 3 years predicted better the prognosis of VLBWIs with DQ ≥ 85 at age 6 years than their growth profiles. …”
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3282
TWIST1 regulates HK2 ubiquitination degradation to promote pancreatic cancer invasion and metastasis
Published 2025-02-01“…Findings highlight the importance of targeting these molecular pathways, which could lead to improved diagnostic and therapeutic approaches, ultimately enhancing patient outcomes and prognosis.…”
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3283
MicroRNA-21 as a Regulator of Cancer Stem Cell Properties in Oral Cancer
Published 2025-01-01“…Oral squamous cell carcinoma (OSCC) is a highly aggressive malignancy with poor prognosis, mainly due to the presence of cancer stem cells (CSCs), a small subpopulation of cells that contribute to therapy resistance and tumor progression. …”
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3284
ICAM1 blockade improves ischemic muscle reperfusion in diabetic mice
Published 2025-01-01“…Abstract Background Chronic Limb-Threatening Ischemia (CLTI) represents the most advanced stage of Peripheral Artery Disease (PAD) and is associated with dire prognosis, characterized by a substantial risk of limb amputation and diminished life expectancy. …”
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3285
Clinical Evaluation of Subcutaneous Lactate Measurement in Patients after Major Cardiac Surgery
Published 2009-01-01“…During critical illness, the addition of a lactate sensor might enhance prognosis and early intervention. Our objective was to evaluate SAT as a site for lactate measurement in critically ill patients. …”
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3286
The Number of Patients with Acute Myocardial Infarction Decreased and Door-to-Balloon Time Delayed in COVID-19
Published 2021-01-01“…We collected clinical characteristics, comorbidities, treatment, prognosis, and key time segments to analyze. Results. …”
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3287
Diffusion MRI-based analysis of functional alterations of the glymphatic system in children with non-lesional epilepsy
Published 2025-03-01“…DTI-ALPS and free-water mapping are useful noninvasive approaches for examining glymphatic function in children with NLE, with the FW-WM potentially serving as an imaging marker for disease progression and predicting clinical prognosis in children with NLE.…”
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3288
Tumor characteristics and survival rate of axillary metastatic breast cancer patients: a three decades retrospective cohort study
Published 2025-02-01“…Conclusion: The axillary lymph node status has been considered as one of the fundamental factors determining the therapeutic strategy and prognosis of BC patients, which has an association with tumor characteristics. …”
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3289
Big Earth data processing using machine learning for integrated mapping of the dead sea fault, Jordan
Published 2021-12-01“…GIS applications encourage geological prospective modeling by visualizing data aimed at the prognosis of mineral resources. However, automatization using machine learning for big Earth data processing provides the speed and accurate processing of multisource massive datasets. …”
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3290
Exploring the Prognostic Role of Trop-2, CD47, and CD163 Expression Levels on Survival Outcomes in Patients with Triple-Negative Breast Cancer
Published 2025-01-01“…Although CD47 and CD163 showed trends for poorer prognosis, their significance was not confirmed. These findings offer promising prospects for future studies on combined antibody–drug conjugates (ADCs), as they may present opportunities to address multiple resistance mechanisms in the management of TNBC and enhance clinical outcomes.…”
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3291
Non-cancerous CT findings as predictors of survival outcome in advanced non-small cell lung cancer patients treated with first-generation EGFR-TKIs.
Published 2025-01-01“…<h4>Conclusion</h4>In advanced EGFR-mutated NSCLC patients, assessing pre-treatment prognosis is warranted to predict the survival outcome and guide decision regarding EGFR-TKI therapy. …”
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3292
Acute Liver Failure Occurring during the First Trimester of Pregnancy Successfully Treated with Living Donor Liver Transplantation
Published 2013-01-01“…Liver transplantation has been reported as one of the treatment options for ALF during pregnancy with the prognosis varying depending on the trimester, from living donor or deceased donor liver transplantation. …”
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3293
Evaluating survival outcomes and treatment recommendations in resectable gastric cancer
Published 2025-01-01“…Therapies combining radiation with chemotherapy and extended lymph node dissection correlated with a worse prognosis compared to PC and NC. Despite the association with improved outcomes, national data reveals low utilization rates for PC.…”
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3294
Association of triglyceride-glucose related indices with mortality among individuals with MASLD combined with prediabetes or diabetes
Published 2025-02-01“…Conclusions Elevated levels of TyG, TyG-BMI, TyG-WHtR, TyG-WWI, and TyG-WC indices were associated with a poorer prognosis in MASLD patients with prediabetes or diabetes, with TyG-WWI being the strongest predictor.…”
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3295
Clear Cell Carcinoma Arising from Cesarean Section Scar Endometriosis: Case Report and Review of the Literature
Published 2014-01-01“…We report a case of clear cell adenocarcinoma arising in the abdominal wall from endometriosis tissues following cesarean section and review previous literature to achieve the optimal treatment and better prognosis. Case Presentation. A 60-year-old woman presented with a growing mass at the left side of a cesarean section scar. …”
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3296
Co-modulation of a circular form of PCDH11Y during neuroendocrine differentiation of prostate cancer
Published 2025-02-01“…A subset of CRPC evolves into treatment-emergent neuroendocrine prostate cancer (t-NEPC), an aggressive form characterized by poor prognosis. Currently, there is no reliable biomarker for early detection of t-NEPC. …”
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3297
Pre-diagnostic risk factors for brain cancer incidence and survival: insights from the Golestan Cohort Study
Published 2025-02-01“…Conclusions Our results indicate a complex interplay of demographic and life style risk factors influencing both the incidence and prognosis of brain cancer. Further research is mandated to inform policy makers of potentially effective preventive initiatives to reduce the burden of this cancer.…”
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3298
Associations between sedentary behaviour and sarcopenia among patients aged 40 and older with chronic obstructive pulmonary disease: a cross-sectional study
Published 2025-01-01“…Abstract Background Patients with chronic obstructive pulmonary disease (COPD) and sarcopenia experience poorer clinical prognosis. Although sedentary behaviour (SB) is common risk factor for COPD, its relationship with sarcopenia in this specific population remains unclear. …”
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3299
NKX6.3 modulation of mitotic dynamics and genomic stability in gastric carcinogenesis
Published 2025-01-01“…Abstract Background Gastric cancer remains a significant global health challenge, characterized by poor prognosis and high mortality rates. Mitotic integrity and genomic stability are crucial in maintaining cellular homeostasis and preventing tumorigenesis. …”
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3300
Wnt5a Increases Properties of Lung Cancer Stem Cells and Resistance to Cisplatin through Activation of Wnt5a/PKC Signaling Pathway
Published 2016-01-01“…The development of chemoresistance to cisplatin regimens causes a poor prognosis in patients with advanced NSCLC. The role of noncanonical Wnt signaling in the regulation of properties of lung cancer stem cells and chemoresistance was interrogated, by accessing capacities of cell proliferation, migration, invasion, and clonogenicity as well as the apoptosis in A549 cell lines and cisplatin-resistant A549 cells treated with Wnt5a conditional medium or protein kinase C (PKC) inhibitor GF109203X. …”
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