Oncogene OSTM1 Promotes Gastric-Cancer Metastasis by Modulating the Metastatic Microenvironment Through Altered Tumor-Cell Autocrine Signaling by Yucheng Tang, Yi Guo, Jiangyi Feng, Ziwei Wang

“…Gastric cancer remains a malignancy with high incidence, mortality rates, and poor prognosis globally. Osteoclastogenesis-associated transmembrane protein 1 (OSTM1), a transmembrane protein overexpressed in various tumors, has unclear functions in gastric-cancer progression. …”
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Malignant Lymphoma in the Parasellar Region by Takao Koiso, Hiroyoshi Akutsu, Shingo Takano, Tetsuya Yamamoto, Eiichi Ishikawa, Yasushi Okoshi, Akira Matsumura

“…We describe a patient with SPL showing a good prognosis. A 78-year-old woman presented with diplopia, left ptosis, and back pain. …”
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Cardiac Injury Biomarkers and the Risk of Death in Patients with COVID-19: A Systematic Review and Meta-Analysis by Sami H. Alzahrani, Mohammed W. Al-Rabia

“…Cardiac complications may develop in a proportion of patients with the novel coronavirus disease (COVID-19), which may influence their prognosis. Objectives. To assess the role of cardiac injury biomarkers measured on admission and during hospitalization as risk factors for subsequent death in COVID-19 patients. …”
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Association between blood–urea–nitrogen-to-albumin ratio and in-hospital mortality in patients diagnosed with coronavirus disease 2019: a retrospective cohort study by Ruoqing Zhou, Dianzhu Pan

“…Conclusions BAR exhibited a significant relationship with in-hospital mortality in patients with COVID-19, suggesting that a higher BAR is associated with a poorer prognosis. However, further research is required to confirm these findings.…”
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Perilipin2-dependent lipid droplets accumulation promotes metastasis of oral squamous cell carcinoma via epithelial-mesenchymal transition by Jiayu Zhang, Jianmin Peng, Siyu Wang, Li Wang, Yutong Sun, Juan Xia, Bin Cheng, Qinchao Hu

“…OSCC patients with higher PLIN2 expression possessed poorer prognosis and higher sensitivity to chemotherapy drugs (1S,3 R)-RSL3 and ML-210. …”
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Diagnosis of Parkinson’s disease by eliciting trait-specific eye movements in multi-visual tasks by Maosong Jiang, Yanzhi Liu, Yanlu Cao, Shufeng Xia, Fei Teng, Wenzhi Zhao, Yongzhong Lin, Wenlong Liu

“…Our method provides physicians with a new auxiliary tool to improve the prognosis and quality of life of PD patients.…”
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Clinical Behavior of Bladder Urothelial Carcinoma in Young Patients: A Single Center Experience by Volkan Sen, Ozan Bozkurt, Omer Demir, Ahmet Adil Esen, Ugur Mungan, Guven Aslan, Aykut Kefi, Ilhan Celebi

“…We aimed to evaluate the clinical characteristics and prognosis of bladder urothelial carcinoma patients under the age of 40 years. …”
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Applicability of indocyanine green fluorescence tracing with subserosal dye injection in laparoscopic lymph node dissection for gastric cancer: a preliminary study by Zhangwei Yang, Pengwei Wang, Dandan Bao, Yi-Ren Hu, Senrui Chen, Yi Huang, Pingting Li

“…Adequate lymph node dissection is crucial for accurate staging and improving patient prognosis. However, the complex distribution of lymph nodes around the stomach poses a significant challenge for thorough dissection. …”
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β-Catenin Regulation in Sporadic Colorectal Carcinogenesis: Not as Simple as APC by Ernst Fredericks, Gill Dealtry, Saartjie Roux

“…Elevated peroxisome proliferator-activated receptor γ (PPARγ) expression has reduced risk of carcinogenesis and good overall prognosis in established CRC. Activation of PPARγ has inhibitory effect on β-catenin. …”
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Autoimmune hepatitis under the COVID-19 veil: an analysis of the nature of potential associations by Chaojie Yu, Wenrui Wang, Qian Zhang, Zhenjing Jin

“…In this review, we analyse the clinical-immunological characteristics, risks associated with severe disease progression, and prognosis for AIH patients infected with SARS-CoV-2; discuss the detrimental effects exerted by SARS-CoV-2 on hepatic function; summarise the mechanisms and attributes leading to new-onset AIH; as well as provide insights into how vaccination may interfere with autoimmunity processes. …”
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Unveiling the antiglioblastoma potential of harmicens, harmine and ferrocene hybrids by Poje Goran, Šakić Davor, Marinović Marina, You Jiangyang, Tarpley Michael, Williams Kevin P., Golub Nikolina, Dernovšek Jaka, Tomašič Tihomir, Bešić Erim, Rajić Zrinka

“…The poor prognosis of glioblastoma multiforme, inadequate treatment options, and growing drug resistance urge the need to find new effective agents. …”
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A Physically Based Runoff Model Analysis of the Querétaro River Basin by Carlos Javier Villa Alvarado, Eladio Delgadillo-Ruiz, Carlos Alberto Mastachi-Loza, Enrique González-Sosa, Ramos Salinas Norma Maricela

“…This methodology can be a strong base for sustainable water management in a basin, the prognosis and effect of land-use changes, and availability of water and also can be used to determine application of known basin parameters, basically depending on land-use, land-use changes, and climatological database to determine the water balance in a basin.…”
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Severe central nervous system injury in 9 children with COVID-19 by Peipei Zhang, Meiyun Xin, Yingge Bai, Xueyun Ren, Na Li

“…Abstract Purpose To investigate the clinical features and prognosis of severe central nervous system (CNS) injury in children caused by coronavirus disease 2019 (COVID-19). …”
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Treatment Patterns and Outcomes Among Patients With Advanced or Recurrent Endometrial Cancer Initiating First-Line Therapy in the United States by Robert L. Coleman, Jamie Garside, Jean Hurteau, Joehl Nguyen, Monica Kobayashi

“…**Conclusions:** Patients with recurrent/advanced EC have a poor prognosis, highlighting the need for therapies with more durable benefits.…”
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Comparative transcriptomic analysis of primary endometrial cancer and bone metastatic cancer: metastasis-associated genes and abnormal cell cycle regulation by Qinmin Wu, Feng Li, Yunlong Zhang, Siying Li, Chuan Xiang

“…Once bone metastasis develops, it often indicates a poor prognosis. Current research on the bone metastasis of primary tumors suggests that tumor cells primarily colonize bones through hematogenous metastasis and are stimulated to grow by the bone microenvironment. …”
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CLDN4 as a Novel Diagnostic and Prognostic Biomarker and Its Association with Immune Infiltrates in Ovarian Cancer by Pan Hu, Li Lei, Ying Wang, Xue Tian, Xia Wei, Ni Jiang, Lubin Liu

“…Analysis using both univariate and multivariate techniques revealed that CLDN4 expression was an independent factor associated with a poor prognosis for OS and DSS. Based on multivariate analysis, the C-indexes and calibration plots of the nomogram suggested an effective predictive performance for OC patients. …”
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The role of MRO as an M2 macrophage-associated gene in non-small cell lung cancer: insights into immune infiltration, prognostic significance, and therapeutic implications by Yue Gu, Miaosen Zheng, Jing Xie

“…Conclusions MRO is a critical M2 macrophage-associated gene in NSCLC, influencing immune infiltration and prognosis. It may serve as a biomarker for prognostication and a target for therapeutic intervention in NSCLC.…”
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Nutritional support in early phases of acute pancreatitis: fashionable trend and essential reality by Ye. Ye. Achkasov, A. V. Pugayev, G. V. Dyatchina, V. I. Posudnevsky, Zh. G. Nabiyeva, P. V. Melnikov

“…It was demonstrated, that from the pathogenic point of view total parenteral nutrition is most justified in the phase of enzyme toxemia and intermediate phase of AP for 7 to 14 days and more in relation to the initial prognosis of disease severity. To establish a true role of early enteric feeding in AP treatment, it is necessary to continue monitoring of primary attacks, preventing its relapses, and to study effect of different types of enteric feeds on the level of APUD system hormones, that regulate pancreatic secretion.Conclusion. …”
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BRAF mutant appendiceal adenocarcinoma differs from colorectal cancer but responds to BRAF-targeted therapy by Vinay K. Pattalachinti, Emaan Haque, Mahmoud Yousef, Abdelrahman Yousef, Saikat Chowdhury, Michael Overman, Christine M. Parseghian, Van K. Morris, Bryan Kee, Ryan W. Huey, Kanwal Raghav, Colin M. Court, John Paul Shen

“…Unlike CRC, BRAF V600E AA is not associated with poor prognosis, female sex, microsatellite instability, mucinous histology, or poor differentiation. …”
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A Case of Systemic Lupus Erythematosus/Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Overlap Syndrome with Dissociated Pathological and Immunological Findings by Kazuhiko Kato, Tetsuya Kawamura, Risa Terashima, Yukiko Tsuchiya, Yasuhito Takahashi, Kenji Kasai, Takashi Yokoo

“…In cases where clinical and pathological features appear to conflict, as in the present case, a treatment strategy decision should be based on pathological and immunological findings to improve the prognosis of OS.…”
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