RNA modification writer-based immunological profile and genomic landscape of tumor microenvironment in lung adenocarcinoma by Qiang Xu, Lingyu Kong, Zhezhu Han, Xiuying Jin, Mingyan Ding, Zhengri Piao, Songnan Zhang

“…Additionally, we constructed a risk-score model based on six LUAD prognosis-associated differentially expressed RNA modification writer genes. …”
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Potential Role of ANGPTL4 in the Cross Talk between Metabolism and Cancer through PPAR Signaling Pathway by Laura La Paglia, Angela Listì, Stefano Caruso, Valeria Amodeo, Francesco Passiglia, Viviana Bazan, Daniele Fanale

“…Several studies showed that high levels of ANGPTL4 are associated with poor prognosis in patients with various solid tumors, suggesting an important role in cancer onset and progression, metastasis, and anoikis resistance. …”
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High Expression of Polo-Like Kinase 1 Is Associated with Early Development of Hepatocellular Carcinoma by Wei Sun, Qi Su, Xiankui Cao, Bin Shang, Aishan Chen, Hongzhuan Yin, Baolin Liu

“…In addition, the correlation of PLK1 expression with clinicopathological factors or prognosis of HCC was analyzed. Results showed that the expression of PLK1 was increased significantly in HCC tissues than that of corresponding normal liver tissues. …”
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Tumor-derived colorectal cancer organoids induce a unique Treg cell population by directing CD4+ T cell differentiation by Sonia Aristin Revilla, Cynthia L. Frederiks, Stefan Prekovic, Enric Mocholi, Onno Kranenburg, Paul J. Coffer

“…Summary: In colorectal cancer (CRC), increased numbers of tumor-infiltrating CD4+ regulatory T (Treg) cells correlate with tumor development, immunotherapy failure, and poor prognosis. To assess how CRC tumors directly modulate Treg cell differentiation, we developed an in vitro co-culture system using CD4+ T cells from Foxp3eGFP mice and CRC tumor-derived organoids. …”
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The average relative dose intensity of R‐CHOP is an independent factor determining favorable overall survival in diffuse large B‐cell lymphoma patients by Monika Długosz‐Danecka, Sebastian Szmit, Tomasz Ogórka, Aleksander B. Skotnicki, Wojciech Jurczak

“…Abstract The prognosis of diffuse large B‐cell lymphoma (DLBCL) patients depends on lymphoma‐ and patient‐related risk factors and is best estimated by the international prognostic index (IPI). …”
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High sensitivity c-reactive protein and homocysteine in patients with ischemic cerebrovascular disease by Marisol Peña Sánchez, Cesarina Lisselotte Torres Vázquez, Melany Betancourt Loza, Alina González-Quevedo Monteagudo, Marianela Arteche Prior, María Caridad Menéndez Saiz

“…<p><strong>Foundation:</strong> High-sensitivity C-reactive protein and homocysteine seem to be related to ischemic cerebrovascular disease, but their findings on the risk and prognosis of this disease are controversial and inconclusive.…”
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Agreement Between Tele- and Face-to-Face Assessment of Neuromotor Development in High-Risk Children by Ana Isabel Rubio-López, Marie Carmen Valenza, Julia Raya-Benítez, Geraldine Valenza-Peña, Irene Cabrera-Martos, Laura López-López, Ángela Benítez-Feliponi

“…Background: Early interventions in high-risk children seek to improve prognosis, minimize developmental delays, and prevent functional deterioration. …”
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Transferrin receptor-1 and ferritin heavy and light chains in astrocytic brain tumors: Expression and prognostic value. by Ann Mari Rosager, Mia D Sørensen, Rikke H Dahlrot, Steinbjørn Hansen, David L Schonberg, Jeremy N Rich, Justin D Lathia, Bjarne W Kristensen

“…TfR1 increased with grade (p<0.001), but was not associated with prognosis in the individual grades. FTH and FTL were expressed by tumor cells and cells with microglial/macrophage morphology. …”
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Expression of MxA in esophageal cancer cell lines can influence sensitivity to chemotherapeutic agents but this does not require apoptosis by R. M. Hayes, T. R. O'Donovan, S. L. McKenna

“…Abstract Esophageal cancer is a poor prognosis cancer characterized by intrinsic or acquired resistance to chemotherapeutic agents. …”
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Challenges in Diagnosis and Management of SLE in Africa: An Online Survey by Farhanah Paruk, Dzifa Dey, Anisa Mosam, Oluwaytoyin Amira Christina, Mohammed Tikly

“…Conclusion Variable availability of laboratory tests, medications, and supportive services coupled with cost constraints are major impediments to early diagnosis and optimal management of SLE in most of Africa and are likely factors contributing to underreporting and poor prognosis of SLE in Africa.…”
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On the Dual Role of Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) in Human Malignancies by Andreea Calinescu, Gabriela Turcu, Roxana I. Nedelcu, Alice Brinzea, Anastasia Hodorogea, Mihaela Antohe, Carmen Diaconu, Coralia Bleotu, Daniel Pirici, Lucia B. Jilaveanu, Daniela A. Ion, Ioana A. Badarau

“…We reviewed the literature and discussed the various expression patterns of CEACAM1 in different types of tumors, describing its structure and general biologic functions and emphasizing the most significant findings that link this molecule to poor prognosis. The importance of understanding the role of CEACAM1 in cell transformation stands not only in this adhesion molecule’s value as a prognostic factor but also in its promising premise as a potential new molecular target that could be exploited as a specific cancer therapy.…”
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Development of a 3-MicroRNA Signature and Nomogram for Predicting the Survival of Patients with Uveal Melanoma Based on TCGA and GEO Databases by Jun Zuo, Hongquan Ye, Jing Tang, Jianqun Lu, Qi Wan

“…The aim of this study was to apply bioinformatic analysis to develop a robust miRNA signature and construct a nomogram model in uveal melanoma (UM) to improve prognosis prediction. Methods. miRNA and mRNA sequencing data for 80 UM patients were obtained from The Cancer Genome Atlas (TCGA) database. …”
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Research progress of MRI-based radiomics in hepatocellular carcinoma by Xiao-Yun Xie, Rong Chen

“…HCC presents a daunting clinical landscape characterized by nonspecific early symptoms and late-stage detection, contributing to its poor prognosis. Moreover, the limited efficacy of existing treatments and high recurrence rates post-surgery compound the challenges in managing this disease. …”
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The use of premature chromosome condensation to study in interphase cells the influence of environmental factors on human genetic material by Vasiliki I. Hatzi, Georgia I. Terzoudi, Christina Paraskevopoulou, Vasilios Makropoulos, Demetrios P. Matthopoulos, Gabriel E. Pantelias

“…The PCC has been successfully used in problems involving cell cycle analysis, diagnosis and prognosis of human leukaemia, assessment of interphase chromosome malformations resulting from exposure to radiation or chemicals, as well as elucidation of the mechanisms underlying the conversion of DNA damage into chromosomal damage. …”
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Moderate Hypertriglyceridemia Causing Recurrent Pancreatitis: A Case Report and the Literature Review by Vijay Gayam, Amrendra Kumar Mandal, Pavani Garlapati, Mazin Khalid, Arshpal Gill, Khalid Mowyad

“…Emerging literature implicates HTG as an independent indicator of poor prognosis in acute pancreatitis (AP). Despite the paucity of data, the risk of developing AP must be considered even at triglyceride levels lower than 1000 mg/dL.…”
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Adding Water to the Mill: Olmesartan-Induced Collagenous Sprue—A Case Report and Brief Literature Review by Claudine Desruisseaux, Michaël Bensoussan, Etienne Désilets, Hanh-Khiem Tran, Robert Arcand, Germain Poirier, Andrew Wisniewski, Thibaut Manière

“…CS is historically associated with a poor prognosis (Marthey et al., 2014). However, histological and clinical improvements have been described in most studies with concomitant usage of corticosteroids and/or gluten-free diet (Marthey et al., 2014). …”
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Barriers and facilitators to improved sedentary behaviour in coronary heart disease patients: a scoping review by Lili Yang, Chen Wu, Yuting Yang, Qiao Yuan

“…Introduction The majority of patients with coronary heart disease (CHD) are at high sedentary levels, which severely affects patient prognosis and outcome. Despite the proven benefits of reducing sedentary behaviour (SB), intervention studies’ effectiveness has been limited. …”
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Following intravenous thrombolysis, the outcome of diabetes mellitus associated with acute ischemic stroke was predicted via machine learning by Xiaoqing Liu, Miaoran Wang, Rui Wen, Haoyue Zhu, Ying Xiao, Qian He, Yangdi Shi, Zhe Hong, Bing Xu

“…Results indicated that the average accuracy of the XGB model was 0.7355 (±0.0307), outperforming the other models. Key predictors for prognosis post-thrombolysis included the National Institutes of Health Stroke Scale (NIHSS) and blood platelet count. …”
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Results of long-term follow-up of patients with chronic gastritis after <i>H. pylori</i> eradication by T. L. Lapina, A. S. Tertychny, E. R. Nasretdinova, I. M. Kartavenko, A. V. Paraskevova, Ye. Yu. Yur’yeva, O. A. Storonova, A. S. Trukhmanov, V. T. Ivashkin

“…Taking into account both severe atrophy and intestinal metaplasia of antral region and mild atrophy of body of the stomach, as well as positive family history, esophagogastroscopy with biopsy is recommended once per year to this patient.Conclusion. Prognosis and management approach of patients after eradication of H. pylori infection are determined by chronic gastritis in relation to severity of atrophy and intestinal metaplasia of antral region and corpus of the stomach, along with other risk factors for cancer development e.g. positive family history.…”
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Metastatic brain tumors: from development to cutting‐edge treatment by Guilong Tanzhu, Liu Chen, Jiaoyang Ning, Wenxiang Xue, Ce Wang, Gang Xiao, Jie Yang, Rongrong Zhou

“…In recent years, the prognosis for BM patients has improved, and significant advancements have been made in both clinical and preclinical research. …”
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