The Function of SUMOylation and Its Role in the Development of Cancer Cells under Stress Conditions: A Systematic Review by Qi Zhao, Ying Ma, Zugui Li, Kexin Zhang, Minying Zheng, Shiwu Zhang

“…Recurrence and metastasis are the most important factors affecting patient prognosis. Chemotherapeutic drugs and radiation used to treat these tumors mainly interfere with tumor metabolism, destroy DNA integrity, and inhibit protein synthesis. …”
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A post-hoc analysis of risk factors for poor quality of life after surgical treatment of spondylodiscitis by Krishnan Sircar, Dorothee Jochimsen, Charlotte Meyer-Schwickerath, Norma Jung, Nikolaus Kernich, Peer Eysel, Ayla Yagdiran

“…These results can be used to individualize patient information and provide a better assessment of prognosis before surgery.…”
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A Novel Immune-Related Three-Gene Signature and Immune Infiltration Insights in Psoriasis and Chronic Kidney Disease by Yin T, Zhang T, Ma L

“…The differential expression of MX1, DDX58, and ISG20 in these cells suggests that they may be involved to varying degrees in the pathogenic mechanisms of the two diseases.Conclusion: This study provides a theoretical foundation for prognosis assessment and treatment of psoriasis and chronic kidney disease, contributing to a deeper understanding of the immune mechanisms underlying these conditions.Keywords: psoriasis, chronic kidney disease, WGCNA, immune infiltration, single cells…”
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Endocrine Aspects of 4H Leukodystrophy: A Case Report and Review of the Literature by Emma Billington, Geneviève Bernard, William Gibson, Bernard Corenblum

“…Making the diagnosis has important implications for prognosis and management. Progressive neurologic deterioration is expected, and progressive endocrine dysfunction may occur. …”
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Value of alpha smooth muscle actin (αSMA) and inducible nitric oxide synthase (iNOS) in oral squamous cell carcinoma (OSCC): An immunohistochemical approach to tumor stroma categor... by Heba E.M. Youssef, Basant Hamdy AbouZaid

“…Alpha smooth muscle actin (α-SMA) expression by stromal CAFs is linked to higher aggressive tumor behavior and poor prognosis. Inducible nitric oxide synthase (iNOS) is one of the main enzymes producing the free radical, nitric oxide in response to various stimuli. …”
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Liposarcomas of the hypopharynx: a systematic review of the literature by Andrea Corvino, Giuseppe Riva, Matteo Sensini, Massimiliano Garzaro, Giancarlo Pecorari

“…The natural history, imaging features, histology, treatment and prognosis were analysed. Results: The incidence peaked in the sixth and seventh decades. …”
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Glomerular Filtration Result in Patients with Hypertensive Emergencies by Manuel Tasis Hernández, Wendy Talavera Hernández, Valentina Edighill Villanueva, Aliucha María Rodríguez Díaz, Taimy Calvera Castro, Juan Francisco Gastón Del Monte

“…<br /><strong>Conclusions</strong>: patients with hypertensive emergencies who have kidney damage have a worse prognosis, so a more strict follow-up and treatment are justified.…”
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Decoding CKD-induced muscle atrophy through the critical role of lncRNA GAS5 and pyroptosis by Rong Huang, Xinying Tang, Shuang Liu, Lijing Sun

“…Skeletal muscle atrophy is a prevalent complication of chronic kidney disease (CKD) and serves as an indicator of adverse prognosis and poor quality of life; however, the underlying mechanisms remain ambiguous. …”
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Pleomorphic xanthoastrocytoma, case series and review of literature by Farrag Mohammad, Ahmed Abd Essattar Abd Elhakeem, Ahmad Algheriany, Ahmed Elshanawany

“…Conclusion Pleomorphic xanthoastrocytomas are rare neoplasms with a better prognosis in grade 2 than grade 3. Diffusion-weighted imaging technology can be used to differentiate between grade 2 and grade 3 Pleomorphic xanthoastrocytoma preoperatively but further studies on larger samples are needed to confirm the possibility. …”
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How May Coexisting Frailty Influence Adherence to Treatment in Elderly Hypertensive Patients? by Bartosz Uchmanowicz, Anna Chudiak, Izabella Uchmanowicz, Grzegorz Mazur

“…Diagnosis of frailty and of the associated difficulties in adhering to treatment may allow for targeting the older patients with a poorer prognosis and at risk of complications from untreated or undertreated hypertension and for planning interventions to improve hypertension control.…”
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Identified VCAM1 as prognostic gene in gastric cancer by co-expression network analysis by Wenjuan Li, Hong Gao, Jianjun Liu

“…Noteworthy among these, VCAM1 was identified as the central gene linked to patients’ prognosis. Moreover, 72 gastric cancer specimens were collected from The First Affiliated Hospital of University of Science and Technology of China. …”
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ASA score is an independent predictor of 1-year outcome after moderate-to-severe traumatic brain injury by Olivia Kiwanuka, Philipp Lassarén, Alexander Fletcher-Sandersjöö, Charles Tatter, Jonathan Tjerkaski, David W. Nelson, Eric P. Thelin

“…Logistic regression evaluated the contribution of ASA score to the International Mission for Prognosis and Clinical Trials in Traumatic Brain Injury (IMPACT) core + CT outcome prediction model incorporating age, admission GCS, pupillary reactivity, Marshall CT classification, hypoxia, hypotension, epidural hematoma, and subarachnoid hemorrhage. …”
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Individualized Corneal Patching for Treatment of Corneal Trauma Combined with Tissue Defects by Ting Zhang, Yanni Jia, Suxia Li, Weiyun Shi

“…Individualized corneal patching with a minimal graft can save corneal materials, relieve corneal scars, gain a good visual prognosis, and avoid immune rejection in the treatment of corneal trauma combined with tissue defects.…”
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Risk factors affecting COVID-19 case fatality rate: A quantitative analysis of top 50 affected countries by Poh Hui Goh, Wafiah Ilyani Mahari, Norhadyrah Izazie Ahad, Li Ling Chaw, Nurolaini Kifli, Bey-Hing Goh, Siang Fei Yeoh, Khang Wen Goh, Long Chiau Ming

“… Background: Latest clinical data on treatment on coronavirus disease 2019 (COVID-19) indicated that older patients and those with underlying history of smoking, hypertension or diabetes mellitus might have poorer prognosis of recovery from COVID-19. We aimed to examine the relationship of various prevailing population-based risk factors in comparison with mortality rate and case fatality rate (CFR) of COVID-19. …”
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The role of inflammasomes in hepatocellular carcinoma: Mechanisms and therapeutic insights by Valentina Arrè, Roberto Negro, Gianluigi Giannelli

“…Targeting inflammasomes may be a promising therapeutic strategy for the treatment of HCC, offering new opportunities to improve patient prognosis.…”
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The mechanisms of efficacy and safety of Ginkgo biloba extract in acute ischemic stroke: a real-world study by Xiangqian Huang, Xiaoming Zhang, Jiahao Song, Duo Lan, Mengqi Wang, Xunming Ji, Da Zhou, Ran Meng

“…This study aimed to investigate the mechanisms by which GBE improves AIS prognosis, particularly its impact on platelet activity, coagulation function, and the potential risk of bleeding. …”
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Pediatric kidney transplant recipients are at an increased risk for dysbiosis by Gizem Yılmaz, Seha Saygılı, Ayşe Ağbaş, Esra Karabağ Yılmaz, Ahmet Variş, Nur Canpolat

“…Further studies are needed to elucidate the cause-and-effect relationships of these changes and their impact on clinical consequencies and long-term prognosis.…”
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Results of scientific expedition to natural biotopes of the Republic of Tyva in 2019 with the purpose of infectious disease monitoring in wild bird populations by M. S. Volkov, V. N. Irza, A. V. Varkentin, S. V. Rogolyov, A. V. Andriyasov

“…Notwithstanding the absence of AIV very virulent isolate detections in wild bird populations the middle term prognosis for 2020 can be designated as cautious, as the avian influenza epidemic situation is deteriorating globally, especially in the European countries, and the threat of the virus introduction to the Russian territory with migratory birds still exists.…”
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Stress hyperglycemia ratio as an important predictive indicator for severe disturbance of consciousness and all-cause mortality in critically ill patients with cerebral infarction:... by Xiaosheng Li, Li Guo, Yuzhen Zhou, Churan Yuan, Yong Yin

“…Abstract Background Stress hyperglycemia ratio (SHR) has been linked to prognosis of cerebrovascular diseases. Nevertheless, the association between SHR and severe disturbance of consciousness (DC) and mortality among patients with cerebral infarction remains explored. …”
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Higher detectability of amyloid with phenol Congo red compared with alkaline Congo red by Marta Legatowicz-Koprowska, Justyna Szczygieł, Małgorzata Mańczak, Ewa Walczak

“…Early diagnosis, when the deposits are minimal, determines the prognosis and requires histological confirmation. The commonly adopted gold standard technique is alkaline Congo red (ACR) staining, though its sensitivity is limited. …”
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