Stromal Expression of Hypoxia Regulated Proteins Is an Adverse Prognostic Factor in Colorectal Carcinomas by Arjen H. G. Cleven, Manon van Engeland, Bradly G. Wouters, Adriaan P. de Bruïne

“…This study suggests that tumor hypoxia may influence tumor-associated stromal cells in a way that ultimately contributes to patient prognosis.…”
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CHIP away at the marrow-clot connection: inflammation, clonal hematopoiesis, and thromboembolic disease by Angela Todorovski, Tzu-Fei Wang, Marc Carrier, Yan Xu

“…Abstract: Both the incidence and prognosis of arterial atherothrombosis and venous thromboembolism are strongly correlated with increasing age. …”
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Heart Rate Variability in Children with Tricyclic Antidepressant Intoxication by Ener Cagri Dinleyici, Zubeyir Kilic, Sabiha Sahin, Rabia Tutuncu-Toker, Makbule Eren, Zeynel Abidin Yargic, Pelin Kosger, Birsen Ucar

“…HRV can be used as a noninvasive testing method in determining the treatment and prognosis of TCA poisoning patients.…”
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Outcomes after reversed corneal graft rejection: a report from the European VISICORT project by W John Armitage, Uwe Pleyer, Conor C Murphy, Derek Tole, Matthew D Griffin, Jesper Hjortdal, Katja C Iselin, Bertrand Vabres

“…These findings support clinicians by providing information on prognosis after reversed rejection episodes and by giving patients realistic expectations regarding the outcome.…”
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Incidence and Heritability of Gastric Carcinoma in the Belgian Shepherd Dog Population in The Netherlands by Sanne Hugen, Citlalli Limpens, Joris H. Robben, Hille Fieten, Paul J. J. Mandigers

“…Background: Gastric carcinoma in the Tervueren and Groenendael varieties of the Belgian Shepherd dog is commonly recognized and carries a grave prognosis. Information on incidence and heritability is necessary to design an effective selection strategy against this disease. …”
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Elevated Serum Total Bilirubin Level Is Associated with Poor Outcomes in Pediatric Patients with Sepsis-Associated Liver Injury by Yun Cui, Yijun Shan, Rongxin Chen, Chunxia Wang, Yucai Zhang

“…The combined index named “TBIL” and “TBA” showed an AUC of 0.745 (0.626–0.865) for predicting the prognosis in patients with SALI. In addition, the Kaplan–Meier curve indicated that the 28-day survival rate was significantly lower in patients with higher serum TBIL levels (≥64.5 μmol/L) or higher value of TBIL and TBA (≥−0.8902). …”
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A Study Comparing Immunohistochemistry, Fluorescence in situ hybridization, GeneXpert® Breast Cancer STRAT4 Assay for Determining Hormone Receptor, Human Epidermal Growth Factor Re... by Rajaa El Aje, Abdellah Naya, Ayoub Khoaja, Younes Zaid, Mounia Oudghiri, Jodi Weidler, Mehdi Karkouri

“… The accurate assessment of hormone receptors, HER2, and Ki-67 proliferative index provides meaningful information about breast cancer prognosis and prediction of therapy response. Immunohistochemistry, the most common method for evaluating these prognostic biomarkers, can be impacted by numerous variabilities due to pre-analytical/analytical factors and subjective interpretation by pathologists. …”
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Proportions of Proinflammatory Monocytes Are Important Predictors of Mortality Risk in Hemodialysis Patients by Yachung Jeng, Paik Seong Lim, Ming Ying Wu, Tien-Yu Tseng, Chang Hsu Chen, Hung Ping Chen, Tsai-Kun Wu

“…The hemodialysis patients with CD16+ monocyte level in a low but mostly covering normal range also portended a poor prognosis. The findings shed some light for nephrologists on future prospects of early recognizing immune dysfunction and improving early intervention outcomes.…”
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Haemophagocytic Lymphohistiocytosis with Leptospirosis: A Rare but Devastating Complication by B. M. Munasinghe, A. G. Arambepola, N. Pathirage, U. P. M. Fernando, N. Subramaniam, S. Nimalan, T. Gajanthan

“…Secondary haemophagocytic lymphohistiocytosis (sHLH), often associated with an array of infections, malignancies, and autoimmune diseases, is rarely seen with leptospirosis, which carries a relatively poor prognosis even with modern state-of-the-art medical care. …”
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The colorectal cancer microenvironment: Preclinical progress in identifying targets for cancer therapy by Abdo Meyiah, Faez Iqbal Khan, Dia Aldeen Alfaki, Khaled Murshed, Afsheen Raza, Eyad Elkord

“…In CRC, the tumor microenvironment (TME) plays critical roles in tumor growth, progression, patients’ prognosis, and response to treatments. Understanding TME complexities is important for developing effective therapies. …”
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Population features of prevalence and clinical-diagnostic role of NOD2 gene polymorphisms associated with Crohn’s disease by D. A. Kuznetsova, M. V. Merzlyakov, G. V. Vavin, A. S. Razumov, V. L. Emanue

“…It will allow not only to increase efficacy of early diagnosis and the CD risk prognosis, but to define environmental factors affecting clinical utilization of genetic factors that is a premise for development of pathogenic justified management algorithm encompassing both populationbased and regional factors.…”
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Prognostic impact of psychoeducation program completion on inpatients with schizophrenia: a pilot cohort study by Hiroki Noguchi, Seiichiro Tarutani, Yoshiki Takei, Koichi Matsumoto, Takehiko Okamura, Hiroshi Yoneda

“…As psychoeducation and related factors may have a positive effect of the prognosis after discharge, inpatient psychoeducation programs should be flexible enough to provide opportunities for completion.…”
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Characteristics of Optic Neuritis in South Korean Children and Adolescents: A Retrospective Multicenter Study by Kyung-Ah Park, Hee Kyung Yang, Jinu Han, Seong-Joon Kim, Sung Eun Park, Haeng-Jin Lee, Sueng-Han Han, Sei Yeul Oh, Jeong-Min Hwang

“…To analyze the clinical characteristics and prognosis of optic neuritis (ON) in pediatric patients aged <19 years in South Korea. …”
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Radiological insights into fibromuscular dysplasia unveiled by intracranial aneurysms and iliac vein hypoplasia in suspected DVT by Abderrahmane Ibenyahia, MD, Oumaima Elkaddouri, MD, Mounir Salek, MD, Salma Boustani, MD, Soufiane Bigi, MD, Said Adnor, MD, Wassila Bouissar, MD, Soukaina Wakrim, MD

“…Differential diagnosis includes atherosclerotic aneurysms, Ehlers-Danlos syndrome, Marfan syndrome, neurofibromatosis type 1, and polyarteritis nodosa, which must be distinguished through comprehensive imaging and clinical evaluation. The prognosis of FMD varies widely and depends on the extent and location of arterial involvement. …”
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Can physical and psychological factors predict pain recurrence or an exacerbation of persistent non-specific low back pain? A protocol for a systematic review and meta-analysis by Deborah Falla, Michael Mansfield, Janet Deane, Kanya Wongwitwichote, Cho Wai Geoffrey Yu

“…Two independent reviewers will screen titles, abstracts and full texts, assessing the risk of bias with a modified Quality in Prognosis Studies tool. The overall certainty of evidence will be evaluated using an adapted Grading of Recommendations Assessment, Development and Evaluation approach. …”
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Assessment of Patients with a DePuy ASR Metal-on-Metal Hip Replacement: Results of Applying the Guidelines of the Spanish Society of Hip Surgery in a Tertiary Referral Hospital by Jenaro Fernández-Valencia, Xavier Gallart, Guillem Bori, Sebastián Garcia Ramiro, Andrés Combalía, Josep Riba

“…The prognosis associated with the DePuy ASR hip cup is poor and varies according to the series. …”
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Photobiomodulation Can Enhance Stem Cell Viability in Cochlea with Auditory Neuropathy but Does Not Restore Hearing by So-Young Chang, Eunjeong Kim, Nathaniel T. Carpena, Jae-Hun Lee, Doo Hee Kim, Min Young Lee

“…Currently, one of the techniques used for hearing rehabilitation is a cochlear implant that can transform sound into electrical signals instead of inner ear hair cells. However, the prognosis remains very poor if sufficient auditory nerve cells are not secured. …”
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NLRP12/C1qA positive feedback in tumor-associated macrophages regulates immunosuppression through LILRB4/NF-κB pathway in lung adenocarcinoma by Jiaxin Yin, Yuxiao Song, Yang Fu, Jun Wang, Zhimin Zhang, Shasha Ruan, Gaoli Liu, Bicheng Zhang

“…In addition, NLRP12 was predominantly expressed in TAMs and was associated with poorer prognosis in lung adenocarcinoma (LUAD) patients. Knocking down LILRB4 inhibited TAMs protumor polarization. …”
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LINC02389/miR-7-5p Regulated Cisplatin Resistance of Non-Small-Cell Lung Cancer via Promoting Oxidative Stress by Peng Ma, Wen Han, Cunying Meng, Xiaohong Tan, Pengfei Liu, Lei Dong

“…LINC02389 was highly expressed in NSCLC tissues and was correlated with poor prognosis of NSCLC patients. Knockdown of LINC02389 inhibited cell proliferation and promoted cell apoptosis of NSCLC, whereas miR-7-5p knockdown exerted the opposite effects. …”
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Iron metabolism in a mouse model of hepatocellular carcinoma by Dilay Yilmaz, Umesh Tharehalli, Rossana Paganoni, Paul Knoop, Andreas Gruber, Yuexin Chen, Rui Dong, Frank Leithäuser, Thomas Seufferlein, Kerstin Leopold, André Lechel, Maja Vujić Spasić

“…Our data show that iron deficiency is a prevalent phenomenon in p53-deficient liver cancers, which is associated with alterations in Hamp and Tfr1 and a poor prognosis in mice and patients.…”
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