Quantitative Detection of miRNA-21 Expression in Tumor Cells and Tissues Based on Molecular Beacon by Qingxin Liu, Jialong Fan, Chuang Zhou, Liqun Wang, Bin Zhao, Haibin Zhang, Bin Liu, Chunyi Tong

“…As a new tumor marker, the microRNA-21 (miRNA21) level can provide important information for early diagnosis, drug treatment, and prognosis of gastric cancer. With the tool of molecular beacons which can hybridize specifically with target miRNA-21 and generate fluorescence signal change, this paper develops a direct, simple, and rapid method for miRNA-21 detection with detection limit of 0.5 nM. …”
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Novelty of Bioengineered Iron Nanoparticles in Nanocoated Surgical Cotton: A Green Chemistry by Bhavika Turakhia, Saujanya Chikkala, Sejal Shah

“…Hence, iron-nanocoated surgical cotton synthesized using green chemistry, which is antimicrobial and cost effective, might be economically helpful and provide insights to the medical field, replacing conventional wound healing treatments, for better prognosis.…”
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Exploring RNA-Seq Data Analysis Through Visualization Techniques and Tools: A Systematic Review of Opportunities and Limitations for Clinical Applications by Farhana Manzoor, Cyruss A. Tsurgeon, Vibhuti Gupta

“…Overall, this review provides a comprehensive overview of the common visualization tools and their potential applications, which is a useful resource for researchers and clinicians interested in using RNA-seq data for various clinical purposes (e.g., diagnosis or prognosis).…”
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Evaluation of the Selenotranscriptome Expression in Two Hepatocellular Carcinoma Cell Lines by Stefano Guariniello, Giovanni Di Bernardo, Giovanni Colonna, Marcella Cammarota, Giuseppe Castello, Susan Costantini

“…Hence, it needs to identify always new putative markers to improve its diagnosis and prognosis. Since the selenium is able to fight the oxidative damage which is one of the major origins of cell damage as well as cancer, we have recently focused our attention on selenoprotein family and their involvement in HCC. …”
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Phoenix dactylifera L. (date palm) fruit extracts and fractions exhibit anti-proliferative activity against human pancreatic cancer cell lines by Reem A. Al Alawi, Jörg D. Hoheisel, Mohamed Saiel Saeed Alhamdani, Younis Baqi

“…Pancreatic cancer has a very poor prognosis due to its high resistance to chemotherapeutic drugs, late diagnosis, and early metastasis, making it the most aggressive and lethal cancer. …”
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Fibroblast Growth Factor Receptor 3 (FGFR3)–Analyses of the S249C Mutation and Protein Expression in Primary Cervical Carcinomas by Haiyan Dai, Ruth Holm, Gunnar B. Kristensen, Vera M. Abeler, Anne‐Lise Børresen‐Dale, Åslaug Helland

“…These patients had a better prognosis than those with reduced or normal levels, although not statistically significant. …”
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Validation of a hypomorphic variant in CDK13 as the cause of CHDFIDD with autosomal recessive inheritance through determination of an episignature by Jan Fischer, Mariëlle Alders, Marcel M. A. M. Mannens, David Genevieve, Karl Hackmann, Evelin Schröck, Bekim Sadikovic, Joseph Porrmann

“…This highlights the utility of episignatures in variant interpretation, as well as a potential novel diagnostic approach in unsolved cases or for disease prognosis.…”
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Mantle Cell Lymphoma in the Thyroid: A Rare Presentation by Uzma Mohammad Siddiqui, Sarika N. Rao, Pallavi Kanwar Galera, Nahida Islam, Mira S. Torres

“…As in our patient, mantle zone growth pattern and a Ki-67 index < 10% suggest a favorable prognosis. A diagnosis of primary MCL in the thyroid remains rare and staging modalities as well as treatment options continue to evolve.…”
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Association between Platelet to Neutrophil Ratio (PNR) and Clinical Outcomes in STEMI Patients after Successful pPCI: A Secondary Analysis Based on a Cohort Study by Hao Wang, Xiaochun Qing, Hua Wang, Yunfei Gu

“…This study was aimed at investigating whether the platelet-to-neutrophil ratio (PNR) is independently related to the prognosis of patients with ST-elevation myocardial infarction (STEMI) after successful primary percutaneous coronary intervention (pPCI). …”
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Flavonoids as Strong Inhibitors of MAPK3: A Computational Drug Discovery Approach by Amir Taherkhani, Parita Khodadadi, Lida Samie, Zahra Azadian, Zeynab Bayat

“…Mitogen-activated protein kinase 3 (MAPK3) mediates the onset, progression, metastasis, drug resistance, and poor prognosis in various malignancies, including glioma, liver, ovarian, thyroid, lung, breast, gastric, and oral cancers. …”
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Identification of Signal Pathways and Hub Genes of Pulmonary Arterial Hypertension by Bioinformatic Analysis by Rui-Qi Wei, Wen-Mei Zhang, Zhe Liang, Chunmei Piao, Guangfa Zhu

“…Pulmonary arterial hypertension (PAH) is a progressive and complex pulmonary vascular disease with poor prognosis. The aim of this study was to provide a new understanding of the pathogenesis of disease and potential treatment targets for patients with PAH based on multiple-microarray analysis.Two microarray datasets (GSE53408 and GSE113439) downloaded from the Gene Expression Omnibus (GEO) database were analysed. …”
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Noma (cancrum oris): A scoping literature review of a neglected disease (1843 to 2021). by Elise Farley, Ushma Mehta, M Leila Srour, Annick Lenglet

“…Future research should focus on determining the burden and distribution of disease; the true mortality rate, pathogenic cause(s) and the factors that influence prognosis and outcomes after treatment.…”
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Study protocol for a randomized controlled trial: Integrating the 'Time-limited Trial' in the emergency department. by Tadayuki Hashimoto, Rachel K Putman, Anthony F Massaro, Youkie Shiozawa, Katherine McGough, Kerry K McCabe, Judith A Linden, Wei Wang, Shan W Liu, Maura Kennedy, Thanh H Neville, Jacqueline M Kruser, Rebecca L Sudore, Mara A Schonberg, James A Tulsky, Kei Ouchi

“…<h4>Introduction</h4>Time-limited trial (TLT) is a structured approach between clinicians and seriously ill patients or their surrogates to discuss patients' values and preferences, prognosis, and shared decision-making to use specific therapies for a prespecified period of time in the face of prognostic uncertainty. …”
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A Current Overview of Next-Generation Probiotics and Their Prospects in Health and Disease Management by Ke-Yan Loo, Joanne Yuen Heng Thong, Loh Teng-Hern Tan, Vengadesh Letchumanan, Kok-Gan Chan, Learn-Han Lee, Jodi Woan-Fei Law

“…The development of therapeutics with these NGPs could offer alternatives to current treatment strategies to improve disease outcomes and prognosis. Nevertheless, future research is essential to better elucidate the exact mechanisms, safety profiles, and therapeutic applications of these NGPs.  …”
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Correlation between B-Type Natriuretic Peptide and Functional/Cognitive Parameters in Discharged Congestive Heart Failure Patients by Laura Leto, Marzia Testa, Mauro Feola

“…In an elderly HF population, BNP is related not only with clinical, laboratory, and instrumental data but also with multidimensional scales evaluating global status; higher BNP levels are linked with a worse prognosis in terms of mortality and 6-month readmission.…”
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Deep weighted survival neural networks to survival risk prediction by Hui Yu, Qingyong Wang, Xiaobo Zhou, Lichuan Gu, Zihao Zhao

“…In the medical field, using gene expression data to build deep survival neural network models significantly improves accurate survival prognosis. However, it still poses a challenge in building an efficient method to improve the accuracy of cancer-specific survival risk prediction, such as data noise problem. …”
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Triple Local Recurrence of Synovial Sarcoma: A Case Report by Mouli Edward, Kukuh Ali Akbar

“…With proper staging, physicians can better understand disease prognosis and risk of recurrence or metastases. Conclusions: The third recurrence may still happen on SS. …”
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Characterization and Etiopathogenic Approach of Pediatric Renal Biopsy Patients in a Colombian Medical Center from 2007-2017 by Mayerly Prada Rico, Carmen Inés Rodríguez Cuellar, Monica Fernandez Hernandez, Luz Stella González Chaparro, Olga Lucía Prado Agredo, Ricardo Gastelbondo Amaya

“…Renal biopsy is the principal instrument to evaluate the diagnosis and prognosis of children with kidney disease. There are relatively few studies establishing epidemiology of its findings in the pediatric population. …”
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Diagnostic Predictive Value of Tryptase, Serum Amyloid A and Lipoprotein-Associated Phospholipase A2 Biomarker Groups for Large Atherosclerotic Cerebral Infarction by Wenhui Jia, Xia Li, Fang Lei, Fengyun Hu, Fenglian Li, Xueying Zhang, Siyu Liu, Feifei Huang, Changxin Li

“…Biomarkers are closely associated with the occurrence of large atherosclerotic cerebral infarction and can be used as clinical adjuncts for diagnosis and assessment of prognosis.…”
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Pyogenic Brain Abscess: A Comprehensive Review of Epidemiology, Pathogenesis, Diagnosis, and Management by Peyman Eini, Pooya Eini, Latif Gachkar

“…The search terms included "pyogenic brain abscess," "epidemiology," "pathogenesis," "diagnosis," "treatment," "antibiotic therapy," and "prognosis." Relevant articles published in English between 2010 and 2023 were selected, focusing on the most recent advances and evidence-based recommendations for managing pyogenic brain abscesses. …”
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