Rhino-Orbito-Cerebral Mucormycosis: Two Cases with Amaurosis as Presentation, Medical Surgical Management and Follow-Up by Carmen Navarro-Perea, Ignacio Cañas-Zamarra, Enrique Mencía-Gutiérrez, Enrique Revilla-Sánchez, María-Dolores Lago-Llinás, Silvia Pérez-Trigo, Álvaro Bengoa-González

“…Diagnostic confirmation is often delayed, with fatal prognosis in cases in which treatment is not rapidly established. …”
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Deciphering Platelet Kinetics in Diagnostic and Prognostic Evaluation of Hepatocellular Carcinoma by Bibek Aryal, Munekazu Yamakuchi, Toshiaki Shimizu, Jun Kadono, Akira Furoi, Kentaro Gejima, Teruo Komokata, Teruto Hashiguchi, Yutaka Imoto

“…Hepatocellular carcinoma (HCC) largely influences the platelet kinetics, and a growing body of evidence has recognized its association with HCC occurrence or prognosis. This narrative review summarizes the progress made on implicating platelet as a diagnostic and prognostic tool for HCC; the review also dissects the contradictory results from earlier studies and reflects how combining platelet-based information may enable more reliable test for diagnostic and prognostic evaluation of HCC.…”
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Echocardiography in Confirmed and Highly Suspected Symptomatic COVID-19 Patients and Its Impact on Treatment Change by Nadia Benyounes, Clélie Van Der Vynckt, Séverine Tibi, Alexandra Iglesias, Laurence Salomon, Olivier Gout, Thierry Tibi

“…COVID-19 interacts at multiple levels with the cardiovascular system. The prognosis of COVID-19 infection is known to be worse for patients with underlying cardiovascular diseases. …”
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Limfoma Kutis dengan Sindroma Hiper IgE by Fahrul Fahrul, Irza Wahid, Raveinal Raveinal

“…Limfoma kutis adalah limfoma ekstranoduler yang jarang ditemui dan diklasifikasikan berdasarkan variasi manifestasi klinik, histopatologi, imunohistokimia dan prognosis.1,2 90% pasien adalah laki-laki antara usia 20-50 tahun. …”
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Response to induction chemotherapy as a prognostic indicator in locally advanced head and neck squamous cell carcinoma by Francesca Huwyler, Roland Giger, Ruben Bill, Daniel Rauch, Simon Haefliger

“…Patients with laryngeal or hypopharyngeal tumors that did not respond to IC had a significantly poorer prognosis. This effect was not statistically significant in tumors of the oral cavity or oropharynx, where it was only observed as a trend. …”
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Comparative Analysis of US Guidelines for the Management of Cutaneous Squamous Cell and Basal Cell Carcinoma by Amit Mittal, Bharat B. Mittal

“…There are opportunities for research, particularly in the areas of staging, indications for adjuvant treatment in curative settings, extent of nerve invasion and prognosis, and the role of systemic treatments in curative and palliative settings.…”
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The kidney reabsorption-related magnesium depletion score is associated with cardiovascular disease and longitudinal mortality in diabetic kidney disease patients by Zhengxi Zhou, Xiaotian Yao

“…This study aims to explore the relationship between kidney reabsorption-related magnesium depletion score (MDS) and the occurrence of cardiovascular disease (CVD) and prognosis in diabetic disease kidney (DKD) patients. …”
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Rapid Multiorgan Dissemination of Low-Grade Myxofibrosarcoma: A Case Report by Yasutaka Murahashi, Mitsunori Kaya, Tamotsu Soma, Mikito Sasaki, Satoshi Nagoya, Takuro Wada, Toshihiko Yamashita

“…In contrast, the overall risk of distant metastases is generally low. This makes the prognosis for the patients with myxofibrosarcoma definitely good. …”
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TRIM25: A Global Player of Cell Death Pathways and Promising Target of Tumor-Sensitizing Therapies by Wolfgang Eberhardt, Usman Nasrullah, Josef Pfeilschifter

“…Therapy resistance still constitutes a common hurdle in the treatment of many human cancers and is a major reason for treatment failure and patient relapse, concomitantly with a dismal prognosis. In addition to “intrinsic resistance”, e.g., acquired by random mutations, cancer cells typically escape from certain treatments (“acquired resistance”) by a large variety of means, including suppression of apoptosis and other cell death pathways via upregulation of anti-apoptotic factors or through inhibition of tumor-suppressive proteins. …”
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Targeting Invasion: The Role of MMP-2 and MMP-9 Inhibition in Colorectal Cancer Therapy by Alireza Shoari, Arghavan Ashja Ardalan, Alexandra M. Dimesa, Mathew A. Coban

“…Their expression and activity are significantly elevated in CRC, correlating with poor prognosis and lower survival rates. This review provides a comprehensive overview of the pathophysiological roles of gelatinases in CRC, highlighting their contribution to tumor microenvironment modulation, angiogenesis, and the metastatic cascade. …”
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Pan-Cancer Analyses of the Tumor Microenvironment Reveal That Ubiquitin-Conjugating Enzyme E2C Might Be a Potential Immunotherapy Target by Guang-zhao Huang, Ze-qun Chen, Juan Wu, Ting-ru Shao, Chen Zou, Yi-long Ai, Xiao-zhi Lv

“…Previous studies indicated that UBE2C was related to the prognosis of many cancers. In our study, the higher UBE2C expression level meant a terminal clinical stage in 8 cancer types and the expression level of UBE2C was related to TMB in 20 cancer types. …”
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A Rare Report of Infectious Emphysematous Aortitis Secondary to Clostridium septicum without Prior Vascular Intervention by Ciel Harris, Joseph Geffen, Keyrillos Rizg, Stuart Shah, Aaron Richardson, Cherisse Baldeo, Avinash Ramdass

“…The lesson provided will be the epidemiology of emphysematous aortitis, presentation, diagnosis, management, and prognosis through a case report.…”
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Circulating CTRP1 Levels Are Increased and Associated with the STOD in Essential Hypertension in Chinese Patients by Zhengjia Su, Shuya Tian, Wei Liang

“…In conclusion, CTRP1 levels are increased and associated with the STOD (heart and kidney) in essential hypertension, which can be regarded as a novel biomarker in the prediction of prognosis for patients with essential hypertension.…”
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Risk Factors Related to the in-hospital Evolution of Patients with ST-segment Elevation Acute Coronary Syndrome by Chen Shang, Héctor Pérez Assef, Marlene Ferrer Arrocha

“…Its clinical course and prognosis can be modified by various factors. <br /><strong>Objective:</strong> to analyze the risk factors related to the in-hospital evolution of patients with ST-segment elevation acute coronary syndrome admitted to the coronary intensive care unit of the Institute of Cardiology and Cardiovascular Surgery. …”
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Seborrheic Keratoses as the First Sign of Bladder Carcinoma: Case Report of Leser-Trélat Sign in a Rare Association with Urinary Tract Cancer by Aline Stollmeier, Bernardo Augusto Rosario, Bruna Loise Mayer, Gibran Avelino Frandoloso, Francisco Luiz Gomide Mafra Magalhães, Gustavo Lenci Marques

“…The recognition of typical paraneoplastic dermatoses may anticipate the cancer diagnosis and improve its prognosis. Although rarely observed, the sudden appearance and/or rapid increase in number and size of seborrheic keratoses can be associated with malignant neoplasms, known as the sign of Leser-Trélat. …”
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Clinical Manifestations and Treatment Outcomes of Syphilitic Uveitis in a Chinese Population by Rui Zhang, Jiang Qian, Jie Guo, Yifei Yuan, Kang Xue, Han Yue, Ling Chen

“…Early diagnosis and appropriate treatment are important for visual prognosis.…”
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Y-Shaped Bilateral Self-Expandable Metallic Stent Placement for Malignant Hilar Biliary Obstruction: Data from a Referral Center for Palliative Care by R. Di Mitri, F. Mocciaro

“…Malignant hilar strictures are a clinical challenge because of the current therapeutic approach and the poor prognosis. In recent years, self-expandable metallic stents have proven more effective than plastic stents for palliation of malignant hilar strictures, with the bilateral stent-in-stent technique registering a high success rate. …”
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Generation of Whole-Genome Sequencing Data for Comparing Primary and Castration-Resistant Prostate Cancer by Jong-Lyul Park, Seon-Kyu Kim, Jeong-Hwan Kim, Seok Joong Yun, Wun-Jae Kim, Won Tae Kim, Pildu Jeong, Ho Won Kang, Seon-Young Kim

“…Because castration-resistant prostate cancer (CRPC) does not respond to androgen deprivation therapy and has a very poor prognosis, it is critical to identify a prognostic indicator for predicting high-risk patients who will develop CRPC. …”
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Identification of clinical subgroups in anti-SRP positive immune-mediated necrotizing myopathy patients using cluster analysis by Beibei Cui, Hongjiang Liu, Ruiting Liu, Geng Yin, Qibing Xie

“…Results: A total of 116 patients were included in the study, and 3 distinct clinical subgroups were identified: Cluster 3 (acute), Cluster 2 (subacute), and Cluster 1 (poor prognosis). Patients in Cluster 3 exhibited a short disease course (median 3 months), severe muscle weakness (78.38% with Medical Research Council (MRC) score ⩽3), high muscle enzyme levels, and a good response to treatment. …”
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Novel Optical Coherence Tomography Parameters as Prognostic Factors for Stage 3 Epiretinal Membranes by Young Gun Park, Seo Yeon Hong, Young-Jung Roh

“…We aimed to describe the visual prognosis of eyes with ectopic inner foveal layers (EIFLs) after epiretinal membrane (ERM) surgery. …”
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