Lupus Eritematosus Sistemik pada Pria by Fajriansyah Fajriansyah, Najirman Najirman

“…Lupus Eritematosus sistemik merupakan penyakit inflamasi autoimun kronis dengan etiologi yang belum diketahui serta memiliki manifestasi klinis dan prognosis yang sangat beragam. Insiden LES di Amerika serikat sebesar 5,1 per 100.000 penduduk, sementara prevalensi LES di Amerika dilaporkan 52 kasus per 100.000 penduduk dengan rasiowanita dan laki-laki antara 9-14:1. …”
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An Innocent Appearing Subcutaneous Nodule Diagnoses a Small Cell Lung Cancer in a Never-Smoker Female by Nupur Sinha, Masooma Niazi, Gilda Diaz-Fuentes, Richard Duncalf

“…Soft tissue metastases from lung primary are uncommon, mostly from adenocarcinoma, and portend a poor prognosis. Cutaneous metastases from SCLC are exceptionally rare with reported incidence of 0.3% to 0.8%. …”
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CCDC154 knockdown inhibits growth of liver cancer via suppressing expression of Snail by Rulan Ma, Hongmei Nie, Caijing Mo, Dawei Yuan, Kun Zhu, Kang Li

“…Methods The analysis of CCDC154 expression and prognosis was performed using UALCAN, Human Protein Atlas and Kaplan–Meier plotter websites. …”
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Functional and Biological Role of Endothelial Precursor Cells in Tumour Progression: A New Potential Therapeutic Target in Haematological Malignancies by Antonia Reale, Assunta Melaccio, Aurelia Lamanuzzi, Ilaria Saltarella, Franco Dammacco, Angelo Vacca, Roberto Ria

“…This increase is strictly related to the bone marrow microvessel density and correlated with a poor prognosis. The EPCs characterization is a very complex process and still under investigation. …”
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Spontaneous Intraperitoneal Rupture of Bladder Diverticulum: A Rare Cause of Peritonitis by Ahmed Ibrahimi, Adil Kallat, Idriss Ziani, Hachem El Sayegh, Lounis Benslimane, Yassine Nouini

“…Surgical management is the standard approach for intraperitoneal rupture of bladder diverticulum. The prognosis depends on the earliness of treatment, associated comorbidity, and the nature of underlying diseases. …”
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Impact of Extracellular Matrix-Related Genes on the Tumor Microenvironment and Prognostic Indicators in Esophageal Cancer: A Comprehensive Analytical Study by Yinghong Wu, Wenjie Hu, Zhihong Jia, Qiying Zhu, Jinghui Xu, Liang Peng, Renjie Wang

“…Esophageal cancer is a major global health challenge with a poor prognosis. Recent studies underscore the extracellular matrix (ECM) role in cancer progression, but the full impact of ECM-related genes on patient outcomes remains unclear. …”
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Diverse Expression of IL-32 in Diffuse and Intestinal Types of Gastric Cancer by Mladen Pavlovic, Nevena Gajovic, Milena Jurisevic, Slobodanka Mitrovic, Gordana Radosavljevic, Jelena Pantic, Nebojsa Arsenijevic, Ivan Jovanovic

“…Gastric cancer (GC) represents one of the most common cancers worldwide, frequently diagnosed at advanced stages with poor prognosis, indicating on need for new diagnostic and prognostic markers. …”
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Preliminary results of open comparative randomized study PHG-M3/P01-09 «ORION» on application of «Phosphogliv» in combined therapy of chronic hepatitis C by M. V. Mayevskaya

“…Final results of the presented study help to estimate the role of rapid virologic response in the treatment of CHC by standard interferon/ribavirin, to define group of patients for which this mode of therapy is associated with favorable prognosis, and to determine the role of phosphogliv as adjuvant agent in antiviral treatment programs.…”
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Feasibility of Using High-Resolution Computed Tomography Features for Invasiveness Differentiation of Malignant Nodules Manifesting as Ground-Glass Nodules by Xinyue Chen, Benbo Yao, Juan Li, Chunxiao Liang, Rui Qi, Jianqun Yu

“…The invasiveness of the nodule correlates well with the patient’s prognosis. This study aimed to establish a radiomic model for invasiveness differentiation of malignant nodules manifesting as ground glass on high-resolution computed tomography (HRCT). …”
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Predictors of Long-Time Survivors in Nonmetastatic Colorectal Signet Ring Cell Carcinoma: A Large Population-Based Study by Wuguang Zhang, Wenqian Gong, Changhai Wu, Mengting Li, Xiaolong Tu

“…Colorectal signet ring cell carcinoma (SRCC) is a rare and distinct subtype of colorectal cancer (CRC), with extremely poor prognosis and aggressive tumor biological behavior. …”
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MRI-based hip cartilage measures in osteoarthritic and non-osteoarthritic individuals: a systematic review by Jacob L Jaremko, Hector N Aguilar, Michele C Battié

“…Osteoarthritis is a common hip joint disease, involving loss of articular cartilage. The prevalence and prognosis of hip osteoarthritis have been difficult to determine, with various clinical and radiological methods used to derive epidemiological estimates exhibiting significant heterogeneity. …”
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Lipid metabolic reprogramming and associated ferroptosis in osteosarcoma: From molecular mechanisms to potential targets by Zhiyang Yin, Guanlu Shen, Minjie Fan, Pengfei Zheng

“…Key enzymes such as adenosine triphosphate-citrate lyase (ACLY), acetyl-CoA synthetase 2 (ACSS2), fatty acid synthase (FASN) and stearoyl-CoA desaturase-1 (SCD1) are overexpressed in OS and associated with poor prognosis.Based on specific changes in metabolic processes, this review highlights potential therapeutic targets in the lipid metabolism and ferroptosis pathways, and in particular the HMG-CoA reductase inhibitor simvastatin has shown potential in inducing apoptosis and inhibiting OS metastasis. …”
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Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma with Intramuscular Lipoma-Like Component of the Thigh by Chairat Burusapat, Nuttadon Wongprakob, Nutthapong Wanichjaroen, Chatchai Pruksapong, Kantang Satayasoontorn

“…In the patients who presented with deep-seated tumor, distinction between intramuscular lipoma and well-differentiated liposarcoma is important due to the differences in treatment and prognosis. However, atypical well-differentiated liposarcoma with intramuscular lipoma-like component of the thigh is extremely rare. …”
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Recurrent Interstitial Pneumonitis in a Patient with Entero-Behçet’s Disease Initially Treated with Mesalazine by Akihiro Nakamura, Tomoya Miyamura, Brian Wu, Eiichi Suematsu

“…Mesalazine-induced IP is also uncommon but the prognosis is generally good after discontinuation of mesalazine with or without steroid therapy. …”
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Clinicoradiological Manifestations of Melioidosis with Pulmonary Involvement in a Tertiary Hospital Setup by P Prem Ananth, R Anand, R Prathipa, S Raghul Raj, N Nagarajan

“…Our study aims to comprehensively investigate and analyze the epidemiology and clinicoradiological characteristics of melioidosis along with their prognosis. Materials and Methods: This was a single-centered retrospective observational study where the data of 30 culture-positive melioidosis patients admitted to our hospital from August 2020 to August 2023 were collected and analyzed. …”
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Is hypercalcaemia immediately life-threatening? A prospective study by David Trewick, Mathilde Le Borgne, Julie Regnault, Camille Guimard

“…There was no correlation between calcaemia and QTc intervals or Glasgow Coma Scale score. Prognosis was poor, and 43 patients died during the 12 months. …”
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Image Analysis Based Grading of Bladder Carcinoma. Comparison of Object, Texture and Graph Based Methods and Their Reproducibility by Heung‐Kook Choi, Torsten Jarkrans, Ewert Bengtsson, Janos Vasko, Kenneth Wester, Per-Uno Malmström, Christer Busch

“…The large numbers of extracted features were evaluated in relation to subjective grading and to factors related to prognosis using multivariate statistical methods and multilayer backpropagation neural networks. …”
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Epidemiology of Genu Varum Patients In Dr. Soetomo General Academic Hospital Surabaya 2010-2018: A Retrospective Study by Ronaa Nuqtho Hidayatullah, Tri Wahyu Martanto

“…This study aimed to identify the epidemiological characteristics of patients with genu varum to improve prevention, management, and prognosis, and to provide data for future research. …”
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Validation of a Simple Score for Mortality Prediction in a Cohort of Unselected Emergency Patients by Jeannette-Marie Busch, Isabelle Arnold, John Kellett, Mikkel Brabrand, Roland Bingisser, Christian H. Nickel

“…A patients’ general prognosis can be difficult to measure. The Simple Prognostic Score (SPS) was designed to include patients’ age, mobility, aggregated vital signs, and the treating physician’s decision to admit to aid prognostication. …”
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Therapeutic potential of SOX family transcription factors in osteoarthritis by Yue Huang, Zhuo Wang

“…While SOX9 has been utilized as a biomarker to indicate the occurrence and prognosis of osteoarthritis, investigations into other members of the SOX family and the development of targeted treatments around SOX9 are still required.Purpose This article considers the impact of the SOX protein on the development and inhibition of osteoarthritis and highlights the need for therapeutic approaches targeting SOX9, as supported by existing research.Results SOX9 can contribute to the process of osteoarthritis through acetylation and ubiquitination modifications. …”
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