Efficient multi-omics clustering with bipartite graph subspace learning for cancer subtype prediction by Shuwei Zhu, Hao Liu, Meiji Cui

“…Due to the complex nature and highly heterogeneous of cancer, as well as different pathogenesis and clinical features among different cancer subtypes, it was crucial to identify cancer subtypes in cancer diagnosis, prognosis, and treatment. The rapid developments of high-throughput technologies have dramatically improved the efficiency of collecting data from various types of omics. …”
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Rituximab Monotherapy in the Management of a Rare Case of an HIV Associated Lymphoproliferative Disorder by Jason Hew, Fauzia Rana, Louise Zhou

“…This disease exists as two distinct entities: a localized or unicentric CD (UCD) which has a more benign clinical course and multicentric CD (MCD) which is a systemic disease and carries a worse prognosis. MCD is often associated with human immunodeficiency virus (HIV) infection and these patients are usually coinfected with human herpes virus-8 (HHV-8). …”
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Performance of classification criteria for Behcet's disease in an Egyptian cohort by Mohamed Ahmed Hussein, Mona I Ellawindi, Gaafar Ragab

“…Conclusions: ICBD 2010 is a very good criteria set to be used in Egyptian BD patients based on its very high sensitivity, accepted specificity, and power of discrimination that enables early patients classification, management, and prognosis.…”
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Therapeutic Potentials of Synapses after Traumatic Brain Injury: A Comprehensive Review by Zunjia Wen, Dong Li, Meifen Shen, Gang Chen

“…Synapses play an important role in TBI; while the understandings on the synaptic participation in the treatments and prognosis of TBI are lacking, more studies in this area are warranted.…”
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Outcome of surgical parathyroidectomy for tertiary hyperparathyroidism in kidney transplant recipients: tertiary hyperparathyroidism should not be ignored, for the sake of precious... by Michio Nakamura, Shinya Takiguchi, Saeko Uehara, Yusuke Tomita

“…Tertiary hyperparathyroidism in kidney transplant recipients negatively impacts allograft and patient survival rates, and parathyroidectomy can be expected to improve prognosis in both kidney recipients and dialysis patients. …”
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Epidemiological and Pathogenic Relationship between Sleep Apnea and Ischemic Heart Disease by Carlos Carpio, Rodolfo Álvarez-Sala, Francisco García-Río

“…Moreover, chronic intermittent hypoxia and oxidative stress have an important role in the pathogenesis of coronary disease and are also fundamental to the development of atherosclerosis and other comorbidities present in coronary artery diseases such as lipid metabolic disorders. Interestingly, the prognosis of patients with coronary artery disease has been associated with obstructive sleep apnea and the severity of sleep disordered breathing may have a direct relationship with the morbidity and mortality of patients with coronary diseases. …”
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Evaluation of Stature Development During Childhood and Adolescence in Individuals with Familial Hypophosphatemic Rickets by Mauro M.S. Borghi, Veronica Coates, Hatim A. Omar

“…The majority of the authors agree that treatment using vitamin D and phosphate enables some statural growth in cases of early diagnosis, reflecting a better prognosis.…”
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Impact of cardiac magnetic resonance on the diagnosis and management of patients with cardiomyopathies by Popa Oana-Andreea, Onciul Sebastian, Badea Thedor, Marian Denisa, Rac-Albu Bogdan, Amzulescu Mihaela, Bugeac Claudia, Chiriac Oana, Tomescu Luminița, Gheorghita Valeriu, Roșu Andrei

“…Cardiac magnetic resonance (CMR) is an essential tool for diagnosis and prognosis in patients with cardiomyopathies. Over the past decades, it has become the gold standard for assessing cardiac function, volumes and mass. …”
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Peripheral Ulcerative Keratitis with Pyoderma Gangrenosum by Adrián Imbernón-Moya, Elena Vargas-Laguna, Antonio Aguilar, Miguel Ángel Gallego, Claudia Vergara, María Fernanda Nistal

“…Early recognition of these manifestations can vary the prognosis by applying the appropriate treatment. We introduce a 70-year-old woman who suffered pyoderma gangrenosum associated with peripheral ulcerative keratitis in her left eye. …”
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Latest Approved Therapies for Metastatic Melanoma: What Comes Next? by Farid Menaa

“…., genomics for personalized medicine, nanomedicine to overcome low free-drug bioavailability and targeting, systematic search of “melanoma stem cells” to enhance the prognosis and develop more valuable theranostics). …”
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A Case of Stage I Vulvar Squamous Cell Carcinoma with Early Relapse and Rapid Disease Progression by Marta Peri, Antonino Grassadonia, Laura Iezzi, Patrizia Vici, Michele De Tursi, Clara Natoli, Nicola Tinari, Marinella Zilli

“…However, the disease can unexpectedly evolve with a dismal prognosis even after an early diagnosis. We report a case of a woman who experienced a rapid, chemorefractory tumor progression after surgery for stage IB vulvar SCC.…”
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Somatic Mutations from Whole Exome Sequencing Analysis of the Patients with Biliary Tract Cancer by Kyong-Ah Yoon, Sang Myung Woo, Yun-Hee Kim, Sun-Young Kong, Sung-Sik Han, Sang-Jae Park, Woo Jin Lee

“…Biliary tract cancer (BTC) is a rare cancer and is associated with a poor prognosis. To understand the genetic characteristics of BTC, we analyzed whole-exome sequencing data and identified somatic mutations in patients with BTC. …”
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Stem Cell Hierarchy and Clonal Evolution in Acute Lymphoblastic Leukemia by Fabian Lang, Bartosch Wojcik, Michael A. Rieger

“…Acute lymphoblastic leukemia (ALL) is a highly malignant cancer of the lymphoid system in the bone marrow with a dismal prognosis after relapse. However, stabile phenotypes and functional data of CSCs in ALL, the so-called leukemia-initiating cells (LICs), are highly controversial and the question remains whether there is evidence for their existence. …”
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Soft Tissue Dehiscence Associated with a Titanium Patient-Specific Implant: A Prosthetic Solution as an Alternative to Soft Tissue Grafting by Sharaf Eldeen M. Abbas, Mohamed A. ELKhashab

“…The resulting infection complicates the prognosis of the implemented implant and necessitates, in some occasions, its removal. …”
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Advances in adjuvant therapy for operable N2 non-small cell lung cancer: a narrative review by Lei Liu, Yilong Mao, Leilei Guo, Chencong Li, Yiqian Wang

“…Meanwhile, the booming development of adjuvant targeted therapy and adjuvant immunotherapy also provides newer therapeutic options for the prognosis of postoperative pN2 stage NSCLC, and some new markers will guide the adaptive application of immune drugs in the future. …”
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TRIM21-mediated PRMT1 degradation attenuates colorectal cancer malignant progression by Menghan Cao, Zhiying Shao, Xingyou Qian, Miaolei Chen, Chuyin Deng, Xintian Chen, Tingting Tang, Kaixu Zhang, Sufang Chu, Junnian Zheng, Jin Bai, Zhongwei Li

“…These findings suggest that TRIM21 holds potential as a valuable predictive biomarker for assessing the prognosis of CRC patients.…”
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Cardiac Transthyretin Amyloidosis: Hidden in Plain Sight by Constantine N. Logothetis, Joel Fernandez, Damian A. Laber

“…Each of these have a distinct pathophysiology, diagnostic work-up, treatment, and prognosis. The patient described in this study was diagnosed with transthyretin cardiac amyloidosis months after presenting with heart failure of unknown etiology. …”
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Could Biomarkers of Bone, Cartilage or Synovium Turnover Be Used for Relapse Prediction in Rheumatoid Arthritis Patients? by Delphine Dénarié, Elodie Constant, Thierry Thomas, Hubert Marotte

“…This unbalance is also associated with joint destruction and prognosis of destruction. No data are available on patients in remission. …”
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Glucose metabolism impairment in major depressive disorder by Fanhao Meng, Jing Wang, Long Wang, Wei Zou

“…These mechanical changes contribute to the pathogenesis of MDD and severely interfere with the prognosis. Herein, we summarized the impairment of glucose metabolism and its pathophysiological mechanisms in patients with MDD. …”
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Ultrasonography of the Kidneys in Healthy and Diseased Camels (Camelus dromedarius) by Mohamed Tharwat

“…In recent years, ultrasonography has been used in camels for scanning of the healthy status as well as evaluation and determining the diagnosis and prognosis of diseased cases. Examples of diseases evaluated by ultrasonography are paratuberculosis, trypanosomiasis, pneumonia, pleurisy, gastrointestinal neoplasms, chronic peritonitis, splenic abscessation, and hepatic disorders. …”
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