Genetic history of the Koryaks and Evens of the Magadan region based on Y chromosome polymorphism data by B. A. Malyarchuk, M. V. Derenko

“…The high frequency of such Y chromosome haplogroups in the Koryaks (16.7 %) and Evens (37.8 %) is indicative of close interethnic contacts during the last centuries, and most probably especially during the Soviet period. The genetic contribution of the European males’ Y chromosome significantly prevails over that of maternally inherited mitochondrial DNA. …”
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Economic impact of potentially inappropriate prescribing and related adverse events in older people: a cost-utility analysis using Markov models by Kathleen Bennett, Frank Moriarty, Tom Fahey, Caitriona Cahir

“…We developed Markov models incorporating the AEs of each PIP, populated with published estimates of probabilities, health system costs (in 2014 euro) and utilities.Participants A hypothetical cohort of 65 year olds analysed over 35 1-year cycles with discounting at 5% per year.Outcome measures Incremental cost, quality-adjusted life years (QALYs) and incremental cost-effectiveness ratios with 95% credible intervals (CIs, generated in probabilistic sensitivity analysis) between each PIP and an appropriate alternative strategy. …”
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Dynamic assessment of long-term survival in survivors with stage III non-small cell lung cancer: a novel conditional survival model with a web-based calculator by Xiangdi Meng, Xiangdi Meng, Peihe Wang, Jie Liu, Daqing Sun, Zhuojun Ju, Yuanyuan Cai

“…BackgroundConditional survival (CS) analysis can estimate further survival probabilities based on the time already survived, providing dynamic updates for prognostic information. …”
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Investigating the Suitability of Partial Replacement of Basalt with Scoria as a Base Course Material for a Flexible Pavement. by Wambei, Allan

“…They are two types of scoria in Uganda with probably different properties that is black and red Scoria. …”
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Two-Step Transfer Learning Improves Deep Learning–Based Drug Response Prediction in Small Datasets: A Case Study of Glioblastoma by Jie Ju, Ioannis Ntafoulis, Michelle Klein, Marcel JT Reinders, Martine Lamfers, Andrew P Stubbs, Yunlei Li

“…The oxaliplatin-based TL improved the performance probably by increasing the weights of cell cycle-related genes, which relates to the TMZ response processes. …”
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Impact of irradiation conditions on therapy of Lewis lung carcinoma in mice using glucose-ethylenediamine carbon dots by Pavlo Lishchuk, Halyna Kuznietsova, Taisa Dovbynchuk, Nataliia Dziubenko, Liudmyla Garmanchuk, Sergei Alekseev, Mykola Isaiev, Nataliya Pozdnyakova, Artem Pastukhov, Nataliya Krisanova, Tatiana Borisova, Vladimir Lysenko, Valeriy Skryshevsky

“…GE-NP-treated mice had evidence of the probable protection of the liver and attenuating the systemic consequences of tumor growth, as evidenced by normalization of serum aspartate aminotransferase (ASAT), and lactate dehydrogenase (LDH) levels, compared to vehicle-dosed tumor-bearing animals. …”
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Eficacia y seguridad clínica del itolizumab en fase de inducción, en pacientes con psoriasis grave by Maritza Batista Romagosa, Olaine Regla Gray Lovio, Leopoldina Falcón Lincheta, Teresita Pérez Alonso, Beatriz Mantecón Fernández, Aleida Urquiza Rodríguez, Liliana Almenares Soria, Yaimarelis Saumell Nápoles, Ana Rosa Valls Hung, Isabel Vicente Gómez

“…Resultados: El análisis del área de afectación de psoriasis arrojó un rápido y sostenido descenso de sus valores; prevalecieron los eventos adversos relacionados con la administración del producto en investigación, de aparición inmediata, ligeros, muy probables y no serios. Conclusiones: El itolizumab es seguro y eficaz en el 96 % de los pacientes psoriásicos graves durante los esquemas de inducción. …”
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Racial Disparities in Cancer Guideline-Concordant Treatment Using Surveillance, Epidemiology, and End Results Data for Patients With NSCLC by Eric Ababio Anyimadu, MS, Jacklyn M. Engelbart, MD, Jason Semprini, PhD, Amanda Kahl, MPH, Cameron Trentz, MS, John M. Buatti, MD, Thomas L. Casavant, PhD, Mary E. Charlton, PhD, Guadalupe Canahuate, PhD

“…Methods: Using data of the Surveillance, Epidemiology, and End Results on 377,370 patients with NSCLC, we derived a GCIT indicator based on National Comprehensive Cancer Network guidelines. Observed probabilities and logistic regression models adjusted for age, disease stage, and race were used to assess racial disparities in treatment and survival, with the Kaplan-Meier method evaluating survival rates. …”
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Phenolic Compounds and Pharmacological Potential of <em>Lavandula angustifolia</em> Extracts for the Treatment of Neurodegenerative Diseases by Olha Mykhailenko, Viktoriia Hurina, Nataliia Herbina, Yuliia Maslii, Liudas Ivanauskas, Inna Vladymyrova, Dmytro Lytkin, Zigmantas Gudžinskas, Hanna Severina, Olena Ruban, Victoriya Georgiyants

“…The water extract showed higher antioxidant (total 50.85 mg/g) and neuroprotective activity, probably due to synergistic interactions among the components. …”
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Measurement of Circulating 1,25-Dihydroxyvitamin D: Comparison of an Automated Method with a Liquid Chromatography Tandem Mass Spectrometry Method by Armin Zittermann, Jana B. Ernst, Tobias Becker, Jens Dreier, Cornelius Knabbe, Jan F. Gummert, Joachim Kuhn

“…The clinical relevance of circulating 1,25-dihydroxyvitamin D (1,25(OH)2D) is probably underappreciated, but variations in the measurement of this difficult analyte between different methods limit comparison of results. …”
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Assessment of heavy metal contamination in surface sediments: Seasonal influence in the Majes-Camaná basin of the Arequipa region, Peru by María Claudia Cáceres Obada, María Eduarda Fernanda Zegarra Oliveira, Naysha Yamelit Meza Elguera, Stephanie Elena Sosa Pulcha, Abdel Alejandro Portocarrero Banda, Jhon Alfredo Quispe Ortiz, Verónica Salinas Murillo, Hugo Guillermo Jiménez Pacheco

“…A comparison was made with the values proposed by the Interim Freshwater Sediment Quality Guidelines (ISQGs) and Probable Effect Levels (PELs) from the Canadian Sediment Quality Guidelines for the Protection of Aquatic Life, allowing a quantitative evaluation of the environmental impact of 07 heavy metals (Zn, Cu, Cr, Ni, As, Pb, and Cd) along the study points, and to distinguish the possible sources of contamination using box and whisker concentration profiles, mining registries, and vegetation cover by anthropogenic activities. …”
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Acute Infusion-Related Side Effects of Amphotericin B Lipid Complex (ABLC) in Oncohematological Patients: Real-World Data from Brazilian Reference Centers by Francelise Bridi Cavassin, Marcello Mihailenko Chaves Magri, Ariela Victoria Borgmann, Isabela Dombeck Floriani, Marina Rachid Barreto, Tania Zaleski, Fabianne Altruda de Moraes Costa Carlesse, Giovanni Luís Breda, Fábio de Araújo Motta, Diego Rodrigues Falci, Ana Verena Almeida Mendes, Hugo Paz Morales, Patrícia Silva Montes, Mariane Taborda, Talita Teles Teixeira Pereira, João Luiz Baú-Carneiro, Flávio Queiroz-Telles

“…Methods This is an observational retrospective study that included clinical records of patients hospitalized, in a period of 6 years, diagnosed with probable or proved IFI and treated with at least two doses of ABLC. …”
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Multidimensional features of sporadic Creutzfeldt-Jakob disease in the elderly: a case report and systematic review by Jiangfeng Liao, Jiangfeng Liao, Wenming Hu, Wenming Hu, Shiheng Chen, Chunyu Huang, Chunyu Huang, Senwei Dong, Senwei Dong, Wanjin Chen, Wanjin Chen, Xiaochun Chen, Longfei Chen, Longfei Chen

“…This study aims to enunciate the multidimensional features of sCJD in this group.MethodsA case of probable sCJD was reported in a 90-year-old Chinese man with initial dizziness. …”
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Long-Lasting Anti-Inflammatory Activity of Human Microfragmented Adipose Tissue by Sara Nava, Valeria Sordi, Luisa Pascucci, Carlo Tremolada, Emilio Ciusani, Offer Zeira, Moris Cadei, Gianni Soldati, Augusto Pessina, Eugenio Parati, Mark Slevin, Giulio Alessandri

“…We conclude that MFAT is an effective preparation with a long-lasting anti-inflammatory activity probably mediated by a long-term survival of their MSC content that releases a combination of cytokines that affect several mechanisms involved in inflammation processes.…”
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Cooperation Between <i>Rhodococcus qinshengii</i> and <i>Rhodococcus erythropolis</i> for Carbendazim Degradation by Roosivelt Solano-Rodríguez, Fortunata Santoyo-Tepole, Mario Figueroa, Voleta Larios-Serrato, Nora Ruiz-Ordaz, Abigail Pérez-Valdespino, Everardo Curiel-Quesada

“…<i>R. qingshengii</i> RC1 converts carbendazim to 2-AB, the first degradation intermediary, while <i>R. erythropolis</i> RC9 metabolizes the fungicide to its mineralization, probably because <i>R. qingshengii</i> RC1 lacks the <i>hdx</i> gene coding for 2-AB hydroxylase. …”
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The Importance of Coordinated Actions in Preventing the Spread of Yellow Fever to Human Populations: The Experience from the 2016-2017 Yellow Fever Outbreak in the Northeastern Reg... by Márcio Junio Lima Siconelli, Danillo Lucas Alves Espósito, Nathália Cristina Moraes, Julia Maria Ribeiro, Lívia Perles, Maria Angélica Dias, Adolorata Aparecida Bianco Carvalho, Karin Werther, Natália Coelho Couto de Azevedo Fernandes, Silvia D'Andretta Iglezias, Karina Paes Bürger, Benedito Antonio Lopes da Fonseca

“…Public health actions included dissemination of information on YF transmission, investigation of the probable location of NHP infection, characterization of the environment, and subsequent creation of the blueprint from which prevention and control measures were implemented. …”
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Comparison of First- and Second-Generation Drug-Eluting Stents in Patients with Acute Myocardial Infarction and Prediabetes Based on the Hemoglobin A1c Level by Yong Hoon Kim, Ae-Young Her, Myung Ho Jeong, Byeong-Keuk Kim, Sung-Jin Hong, Seunghwan Kim, Chul-Min Ahn, Jung-Sun Kim, Young-Guk Ko, Donghoon Choi, Myeong-Ki Hong, Yangsoo Jang

“…The secondary outcome was probable or definite stent thrombosis (ST). Results. …”
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Transcervical resection of myoma (TCRM): Part I by Peng-Hui Wang, Szu-Ting Yang, Wen-Hsun Chang, Hung-Hsien Liu, Wen-Ling Lee

“…However, to offer a practical standardized consensus for the description and categorization of myomas, the International Federation of Gynaecology &amp; Obstetrics (FIGO) classification system from type 0 to type 8 is established, which is often used for guiding patient management and offering prognostic information, because submucosal myoma (FIGO type 0, 1, probable 2, and possible 3) is frequently associated with symptoms or signs, needing a further intervention. …”
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The Frequency of <i>DPYD</i> c.557A>G in the Dominican Population and Its Association with African Ancestry by Mariela Guevara, Carla González de la Cruz, Fernanda Rodrigues-Soares, Ernesto Rodríguez, Caíque Manóchio, Eva Peñas-Lledó, Pedro Dorado, Adrián LLerena

“…HapB3 is completely absent in Dominican, Mexican, Peruvian, Bangladeshi, and all East Asian and African populations, which probably makes its analysis dispensable in these populations. …”
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Prevalence and epidemiological characteristics of inmates diagnosed with infectious diseases living in a region with a high number of prisons in São Paulo state, Brazil by Charlene Troiani do Nascimento, Danilo Zangirolami Pena, Rogério Giuffrida, Fernanda Nobre Bandeira Monteiro, Francisco Assis da Silva, Edilson Ferreira Flores, Luiz Euribel Prestes-Carneiro

“…Three of those diagnosed with the infection were female and the ratio of female to men was 0.004:1.Conclusions Our findings demonstrate that the number of cases of infectious disease among inmates in the northwestern and western region of São Paulo is probably underestimated, with lower rates of HCV, HBV and syphilis. …”
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