The first experience of two-stage treatment of transsphincteric fistulas of rectum by means of fibrin sealant by S. A. Frolov, A. M. Kuzminov, V. Yu. Korolik, I. S. Bogormistrov, M. O. Chernozhukova, Sh. T. Minbayev

“…In one case at the 3rd month of follow­up transrectal ultrasound revealed the signs of relapse combined to ischioanal fat tissue leak that was probably undiagnosed at initial operation; reoperation was carried out - segmented proctoplasty by mucosal and muscular rectal graft. …”
Get full text

Clinical and endoscopical and morphofunctional scores in evaluation of development of gastroesophageal reflux disease in various age groups by M. A. Osadchuk, A. M. Zolotovitskaya, N. V. Kireyeva, S. N. Nikolenko, I. M. Kvetnoy

“…Its development at patients of all age groups is observed on a background of gastritis with, probably, genetically determined hyperplasia of gastric epithelial cells producing NO-synthase and endothelin-1. …”
Get full text

Undernutrition disrupts jejunal and ileal microbiota and epithelial tissue homeostasis in a pregnant sheep model by Weibin Wu, Muhammad Faheem Akhtar, Jiahong Geng, Huizhen Lu, Muhammad Ajwad Rahim, Jianbo Cheng, Xiaoling Ding, Shengyong Mao, Yanfeng Xue

“…These affected the energy and protein system in the epithelium and reprogrammed substance metabolism and extracellular structures, which probably further influenced cell growth and immune response. …”
Get full text

Borogon: Ethnonym and Ethnic History by Bair Z. Nanzatov, Vladimir V. Tishin

“…It is assumed that the name Borogon among the Yakut population goes back to a word from the Mongolic environment, probably in the original form *boroγan, *boraγan with the literal meaning ‘rain’. …”
Get full text

Role of Intraplate Strike-Slip Earthquakes in Accommodating Convergence Across the Eastern Himalayan Plate Boundary System by Dibyajyoti Chaudhuri, Rupak Banerjee, Ajay Kumar, Shubham Sharma, Supriyo Mitra

“…The strike-slip earthquakes beneath Indo-Burma probably occur due to a complex interplay between the trench-normal slab-pull forces and lateral-shear forces set up by the strike-parallel components of the interplate-coupling resistance and the mantle-drag forces.…”
Get full text

Les quais nos 1, 12 et 13 du port romain de Saint-Lupien à Rezé/Ratiatum (Loire-Atlantique) by Xavier Favreau, Nicolas Ménez

“…Box no. 12 is positioned obliquely relative to the edge of the riverbank and presents a shape that can probably best be restored as a non-rectangular parallelogram. …”
Get full text

Effect of amisulpride on the expression of serotonin receptors, neurotrophic factor BDNF and its receptors in mice with overexpression of the aggregation-prone [R406W] mutant tau p... by E. M. Kondaurova, A. A. Komarova, T. V. Ilchibaeva, A. Ya. Rodnyy, E. A. Zalivina, V. S. Naumenko

“…However, it should be noted that prolonged administration may result in adverse effects such as an increase in Ngfr expression and a decrease in Bdnf and Ntrk2 expression, which is probably indicative of an increase in neurodegenerative processes.…”
Get full text

Les installations portuaires romaines d’Incarville (Eure) by Laurent Paez-Rezende

“…Three architectural complexes on stone foundations in particular testify to buildings that probably functioned mainly as warehouses. The fourth building exhibits a rectangular plan of 3.30 x 2.50 m evoking a small temple or an oratory. …”
Get full text

Effects of early supplemental parenteral nutrition on new-onset infection in adults with acute severe stroke: a single-center retrospective case–control study by Chen Ma, Zhirong Fan, Xuan Wang, Bian Li, Jingjing Zhao, Xiaogang Kang, Wen Jiang, Fang Yang

“…Kaplan–Meier analysis revealed similar cumulative probabilities of new-onset pneumonia and new-onset nosocomial infections in the two groups (P > 0.05). …”
Get full text

Polymorphism of ITS sequences in 35S rRNA genes in Elymus dahuricus aggregate species: two cryptic species? by A. V. Rodionov, K. S. Dobryakova, N. N. Nosov, A. A. Gnutikov, E. O. Punina, A. A. Kriukov, V. S. Shneyer

“…At the moment it is unknown if there are any morphological differences between plants carrying either Northern or Southern dahuricus rDNA. Probably, they are cryptic species, but it is certain that if differences in morphology between the two races exist, they are not associated with signs that are now considered taxonomically significant and are used to separate E. dahuricus s. s., E. franchetii, E. tangutorum, and E. excelsus.…”
Get full text

In Silico Identification of New Anti-SARS-CoV-2 Main Protease (Mpro) Molecules with Pharmacokinetic Properties from Natural Sources Using Molecular Dynamics (MD) Simulations and Hi... by Harrison Onyango, Patrick Odhiambo, David Angwenyi, Patrick Okoth

“…Later, the pharmacophore model was loaded into ZINCPHARMER and screened against the ZINC database to identify new probable drug candidates. The root means square deviation (RMSD) values of the potential drug candidates informed the selection of some of them, which were docked with SARS-CoV-2 Mpro to comprehend their interactions. …”
Get full text

Prediction model for unfavorable treatment outcome for complicated sever acute malnutrition (SAM) in under five children admitted in hospitals at Amhara Region by Almaw Genet Yeshiwas, Zelalem Alamrew Anteneh, Tilahun Degu Tsega, Ahmed Fentaw Ahmed, Chalachew Yenew

“…Decision curve analysis indicated a higher net benefit compared to treating all or none, especially for threshold probabilities above 21%.ConclusionOur model and risk score demonstrate excellent discrimination and calibration, with minimal accuracy loss from the original, ensuring robust predictive performance. …”
Get full text

Cooperación y desigualdad by David Strauss

“…Además, el modelo implica una correlación positiva entre los momentos más altos de la distribución del talento y la prima por cualificaciones que es coherente con la evidencia empírica y es- clarece algunas evoluciones potenciales en la desigualdad debido a cambios en la distribución de la dificultad de las tareas a lo largo del tiempo. Conclusiones: Es probable que los recientes avances en las tecnologías de la informa- ción y la comunicación causen nuevos incrementos en la desigualdad. …”
Get full text

Synergistic Antifungal Activity of Terbinafine in Combination with Light-Activated Gelatin–Silver Nanoparticles Against <i>Candida albicans</i> Strains by Atif Ullah, Fawad Ali, Farman Ullah, Sajid Khan Sadozai, Saeed Ahmed Khan, Sajid Hussain, Abdulwahed Fahad Alrefaei, Sajid Ali

“…The process by which AgNPs boost activity entails the disruption of the fungal cell membrane and its internal components, probably as a result of silver ion release and the generation of free radicals. …”
Get full text

Nitrous Oxide Emissions from Smallholders’ Cropping Systems in Sub-Saharan Africa by Shaankua E. Lemarpe, Collins M. Musafiri, Joseph M. Macharia, Milka N. Kiboi, Onesmus K. Ng’etich, Chris A. Shisanya, Jeremiah Okeyo, Elizabeth A. Okwuosa, Felix K. Ngetich

“…We reviewed the state of N2O emissions from selected cropping systems, drivers that significantly influence N2O emissions, and probable soil N2O emissions mitigation options from 30 studies in SSA cropping systems have been elucidated here. …”
Get full text

A prediction nomogram for residual after negative pressure aspiration for endogenic cesarean scar ectopic pregnancy: a retrospective study by Yan Lei, Na Zhang, Yu Liu, Xin Du

“…Clinical decision curves were constructed to evaluate clinical applicability and quantify the net benefit within a range of threshold probabilities. The model was externally validated in the validation cohort. …”
Get full text

Ocean warming, icebergs, and productivity in the Gulf of Alaska during the Last Interglacial by Maria Luisa Sánchez Montes, Maria Luisa Sánchez Montes, Erin L. McClymont, Hirofumi Asahi, Joseph Stoner, Christopher M. Moy, Sophie Gleghorn, Jerry M. Lloyd

“…We infer that higher coccolithophore abundance with different alkenone configurations suggests a change in the dominant coccolithophore groups and changes in the available nutrients, probably as a result of higher influence of the more saline Alaska Current (AC) and lower influence of the Alaska Coastal Current (ACC) at Site U1418. …”
Get full text

Stability of compact stars in a uniform density background cloud by Ksh. Newton Singh, S. K. Maurya, A. Errehymy, O. Donmez, K. Myrzakulov, T. T. Smitha

“…This radius is far beyond $$R_{\text {BH}} = 8.357$$ R BH = 8.357 km and therefore is most probably a massive NS in the mass gap.…”
Get full text

Giant pit craters on the modern seafloor above magma-induced hydrothermal vent complexes of Scotia Sea, offshore Antarctica by L. Somoza, K. M. Andreassen, A. Plaza-Faverola, T. Medialdea, J. Gafeira, F. J. González, G. R. Dickens

“…Crater reactivation has occurred since 0.9 Ma, although probably episodically. Importantly, at present-day, numerous craters related to sills and fluid pipes populate the seafloor above a young sedimentary basin, and the ocean and atmosphere are receiving massive quantities of 13C depleted carbon. …”
Get full text

Clinical outcomes after immune checkpoint inhibitor-associated acute kidney injury: a cohort study by Vin-Cent Wu, Ting-Ya Yang, Min-Hsiang Chuang, Hong-Min Lin, Heng-Chih Pan, Yun Chou, Jui-Yi Chen

“…Kaplan-Meier analyses coupled with log-rank tests were conducted to estimate the survival probabilities.Setting Data were sourced from the TriNetX database spanning records from 25 March 2011 to 5 April 2024.Participants Patients with cancer aged ≥18 years treated with ICPi with or without AKI occurrence.Primary and secondary outcome measures The primary outcome was all-cause mortality, and secondary outcomes included major adverse kidney events (MAKE), major adverse cardiovascular events (MACE), the composite of MAKE or MACE with death, and end-stage renal disease.Results The study identified 926 patients with cancer who developed ICPi-AKI (mean age, 67.1±11.8 years; 57.4% men). …”
Get full text