Culturing of Giardia lamblia under microaerobic conditions can impact metronidazole susceptibility by inducing increased expression of antioxidant enzymes by Kateryna Starynets, Ana Paunkov, Anja Wagner, Klaus Kratochwill, Christian Klotz, David Leitsch

“…Unfortunately, the number of refractory cases is increasing, which is probably caused, at least in part, by drug resistance. …”
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Polymorphism of genes associated with infectious lung diseases in Northern Asian populations and in patients with community-acquired pneumonia by S. V. Mikhailova, L. V. Shcherbakova, N. I. Logvinenko, I. I. Logvinenko, M. I. Voevoda

“…Carriage of the alleles studied is probably not associated with predisposition to longevity among whites in Siberia. …”
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Transition of clinical biomarker status from childhood into adolescence-A prospective study in children from eight European countries. by Anna Floegel, Paola Russo, Toomas Veidebaum, Michael Tornaritis, Dénes Molnár, Lauren Lissner, Stefaan De Henauw, Luis A Moreno, Wolfgang Ahrens, Manuela Marron, Claudia Börnhorst

“…Latent transition analysis was used to estimate biomarker statuses and transition probabilities; determinants of biomarker status were estimated using mixed-effects models.…”
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Molecular Detection of Antibiotic-Resistant Genes in Pseudomonas aeruginosa from Nonclinical Environment: Public Health Implications in Mthatha, Eastern Cape Province, South Africa by Mojisola Clara Hosu, Sandeep Vasaikar, Grace Emily Okuthe, Teke Apalata

“…Evaluation of resistant profiles and detection of antimicrobial-resistant genes of bacterial pathogens in the nonclinical milieu is imperative to assess the probable risk of dissemination of resistant genes in the environment. …”
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Increments in cytokines and matrix metalloproteinases in skeletal muscle after injection of tissue-damaging toxins from the venom of the snake Bothrops asper by Alexandra Rucavado, Teresa Escalante, Catarina F. P. Teixeira, Cristina María Fernándes, Cecilia Díaz, José María Gutiérrez

“…This suggests that MMP activity was regulated by a highly controlled activation of latent forms and, probably, by a concomitant synthesis of MMP inhibitors. …”
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Development and approval of a Lasso score based on nutritional and inflammatory parameters to predict prognosis in patients with glioma by Huixian Li, Hui Hong, Jinling Zhang

“…The nomogram demonstrated good calibration in both cohorts, indicating strong agreement between predicted and observed outcomes. The threshold probabilities for DCA at 1-, 3-, and 5-years post-surgery in the training and validation cohorts were 0.08~k0.74, 0.25~0.80, and 0.08~0.89, and 0.13~0.60, 0.28~0.81, and 0.25~0.88, respectively.ConclusionsA nomogram incorporating a Lasso score effectively predicted prognosis in glioma patients. …”
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Contribution à l’analyse de la viabilité d’une petite population de gorilles, Gorilla beringei graueri (Hominidae, Primates), par modélisation et simulations de l’écosystème du Mon... by Jean‑Claude Kasolene Kyungu, Jean Mukulire Malekani, Lohandjola Nyamangombe

“…Cette tendance n’a pas changé en faisant une simulation d’une population en déclin ; 2) qu’en introduisant les paramètres de fécondité, de capacité de charge biologique en fonction de la mortalité (taux de fécondité moyen de 4.4 et de mortalité de 0.666 au début), la population de gorilles aura toujours tendance à diminuer ; 3) qu’avec de nouvelles femelles de repeuplement, la population de gorilles pourrait se stabiliser dans les 100 prochaines années ; 4) qu’avec l’analyse génétique pour la recherche de l’identité, les génotypes à partir des échantillons confirment la présence de gorilles mâles et femelles ; 5) qu’avec les pathologies, les résultats des observations et de simulation montrent que l’évolution des infections probables (shigelloses et salmonelloses) est resté constante et linéaire jusqu’à 78 ans. …”
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Quzhou Aurantii Fructus Flavonoids Ameliorate Inflammatory Responses, Intestinal Barrier Dysfunction in DSS-Induced Colitis by Modulating PI3K/AKT Signaling Pathway and Gut Microbi... by Wang H, Huang W, Pan X, Tian M, Chen J, Liu X, Li Q, Qi J, Ye Y, Gao L

“…Lastly, the administration of QAFF via FMT ameliorated the colitis symptoms.Conclusion: QAFF could ameliorate inflammatory responses and intestinal barrier dysfunction in DSS-induced UC mice probably by modulating the PI3K/AKT signaling pathway and gut microbiome, offering promising evidence for the therapeutic potential of QAFF in UC treatment. …”
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The valve-sparing aortic root replacement: Results of the David I technique by B. M. Todurov, I. O. Stetsyuk, O. V. Zelenchuk, I. Yu. Mokryk, L. R. Stetsiuk, V. B. Demyanchuk, N. V. Malova

“…The patients had a good psycho-social component, which probably affected the assessment of other scales. Conclusions. …”
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Lines resistant to downy mildew in the sunflower genetic collection at VIR by V. A. Gavrilova, T. G. Stupnikova, L. G. Makarova, N. V. Alpatieva, Yu. I. Karabitsina, E. B. Kuznetsova, I. A. Anisimova

“…Lines ТА 716-18, VIR 768 and VIR 800 appeared highly resistant to the pathogen and probably possess new resistance genes/alleles introgressed from wild species.…”
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Genome constitution and differentiation of subgenomes in Siberian and Far Eastern endemic species of the genus Elymus (Poaceae) according to the sequencing of the nuclear gene waxy by A. V. Agafonov, S. V. Asbaganov, E. V. Shabanova (Kobozeva), I. V. Morozov, A. A. Bondar

“…The H subgenome contains a 21-bp-long deletion in intron 13 in all Elymus genotypes, probably derived from a common ancestor of the H and P genomes. …”
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The simpler modified fried frailty scale predicts 2-year mortality in older adults with heart failure: a pilot study by Celalettin Küçük, Serdar Özkök, Gülistan Bahat, Ekrem Bilal Karaayvaz, Mustafa Altınkaynak, Alpay Medetalibeyoğlu, Mehmet Akif Karan

“…In a median follow-up of 759 days, cardiomegaly, increased pulmonary artery pressure (PAP) and frailty defined by SMFFS were the only predictors of mortality in older adults with HF after adjustments for age, falls in the previous year, undernutrition, probable sarcopenia, functional impairments, and quality of life [HR (95% CI) were 3.88 (1.05–14.3), 1.05 (1.01–1.09), and 10.96 (1.07–112.05) (p = 0.027); for older age, PAP, and frailty, respectively]. …”
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Le quai no 9 du port romain de Saint-Lupien à Rezé/Ratiatum (Loire-Atlantique) by Jimmy Mouchard, Matthieu Yacger

“…Box no. 12 is positioned obliquely relative to the edge of the riverbank and presents a shape that can probably best be described as a non-rectangular parallelogram. …”
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Vitamin D Deficiency as a Risk Factor for Diabetic Retinopathy: A Systematic Review and Meta-Analysis by Claudia Elena Petrea, Laura Andreea Ghenciu, Roxana Iacob, Emil Robert Stoicescu, Dorel Săndesc

“…Heterogeneity (I² = 89%) was noted, most probably due to geographic differences, varying methodologies for vitamin D measurement, and DR classification approaches. …”
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Cutaneous Anthrax: What is the Hallmark? by Dhani Redhono Harioputro, Arie Kusumawardani, Iin Novita, Evi Nurhayatun, Rahajeng N Tunjungputri, Erni Juwita Nelwan

“…The patient was clinically diagnosed with probable cutaneous anthrax, and was treated with amoxicillin 500 mg orally t.i.d. for three days and paracetamol 500 mg if fever developed. …”
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An association between type A porcine endogenous retrovirus copy number and hematological parameters and gender in miniature pigs by R. B. Aitnazarov, S. V. Nikitin, G. V. Kontsevaya, M. I. Voevoda, N. S. Yudin

“…Presence of multiple copies of PERV-A on the X-chromosome is the most probable cause of such gender-related differences in miniature pigs. …”
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Hepatoprotective Effects of a Novel Trihoney against Nonalcoholic Fatty Liver Disease: A Comparative Study with Atorvastatin by Hamad Abdulsalam Hamad Alfarisi, Muhammad Bin Ibrahim, Zenab B. Hamad Mohamed, Nuraniza Azahari, Asmah Hanim Bt. Hamdan, Che Anuar Che Mohamad

“…Trihoney was able to maintain normal liver function and showed hepatoprotection against progression of NAFLD to NASH probably through hypocholesterolaemic and antioxidant functions.…”
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Smoking habits, awareness and support needs for cessation among people with multiple sclerosis in Australia: findings from an online survey by Roshan das Nair, Ron Borland, Claudia H Marck, Isabelle Weld-Blundell, Lisa Grech, Sarah L White

“…Objectives To assess smoking habits, nicotine use, exposure to passive smoking, awareness of associated harms, and experiences with and preferences for smoking cessation support among people with multiple sclerosis (MS).Design Online survey, convenience sampling.Setting Community setting, Australia.Participants Adults living in Australia with probable or diagnosed MS were recruited via social media and newsletters to participate in 2020.Results Of the 284 participants in our convenience sample, 25.7% were current smokers (n=73) and 38.0% were former smokers (n=108). …”
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HEDDI-Net: heterogeneous network embedding for drug-disease association prediction and drug repurposing, with application to Alzheimer’s disease by Yin-Yuan Su, Hsuan-Cheng Huang, Yu-Ting Lin, Yi-Fang Chuang, Sheh-Yi Sheu, Chen-Ching Lin

“…However, GCNs generally infer association probabilities only for existing drugs and diseases, requiring network re-establishment and retraining for novel entities. …”
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Mortality and Morbidity of Beef Calves in Free-Range Farms in Alentejo, Portugal—A Preliminary Study by Rute Santos, Ana Cachapa, Graça P. Carvalho, Carolina B. Silva, Laura Hernández, Lina Costa, Luísa S. Pereira, Miguel Minas, Helena Vala

“…The number of sudden, unexplained calf deaths seems to have a predictive value on overall calf mortality (from birth to weaning), suggesting that the farms’ management practices probably play an important role in calf mortality throughout the suckling period. …”
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