Negative heterosis for meiotic recombination rate in spermatocytes of the domestic chicken Gallus gallus by L. P. Malinovskaya, K. V. Tishakova, T. I. Bikchurina, A. Yu. Slobodchikova, N. Yu. Torgunakov, A. A. Torgasheva, Y. A. Tsepilov, N. A. Volkova, P. M. Borodin

“…The decrease in recombination rate in F1 is probably determined by difficulties in homology matching between the DNA sequences of genetically divergent breeds. …”
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Assisted Parkinsonism Diagnosis Using Multimodal MRI—The Role of Clinical Insights by Tobias Meindl, Alexander Hapfelmeier, Tobias Mantel, Angela Jochim, Jonas Deppe, Silke Zwirner, Jan S. Kirschke, Yong Li, Bernhard Haslinger

“…Individual predicted probabilities were visualized to address diagnostic uncertainty. …”
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Development and validation of a nomogram to predict recurrence in epithelial ovarian cancer using complete blood count and lipid profiles by Xi Tang, Jingke He, Qin Huang, Yi Chen, Ke Chen, Jing Liu, Yingyu Tian, Hui Wang

“…The calibration curves exhibited good concordance between the predicted survival probabilities and actual observations. Time-dependent C-index curves, integrated discrimination improvement, net reclassification index, and decision curve analysis showed that the nomogram outperformed FIGO staging.ConclusionThis study established and validated a nomogram combining CBC and lipid profiles to predict RFS in patients with optimally debulked EOC, which is expected to aid gynecologists in individualized prognosis assessment and clinical management.…”
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Combining extraction and cultivation methods for soil seed bank analysis increases number of captured species and their similarity to above-ground vegetation by Petr Plohák, Hana Švehláková, Barbara Stalmachová, Miroslava Goňo, Tomáš Dvorský

“…Very low similarity between the species of the soil seed bank from cultivation and extraction method is probably caused by the highly variable distribution of seeds in the soil in time and space.…”
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Water quality characteristics of municipal wastewater treatment plants and the prospect of reclaimed water utilization in lower-middle income and water-scarce areas: A case study o... by Yutong Duan, Hongbo Xi, Zhikai Qin, Ruili Guo, Fang Wang, Yue Yuan

“…Results indicate the seasonal variation in hydraulic load rates, probably affected by heavy rainfall during the rainy season, which posed operational challenges for WWTPs. …”
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Cystic Fibrosis and Reproductive Outcomes: The Latest Insights into Fertility and Pregnancy by Weronika Małagocka, Karol Zagórski, Mateusz Kozik, Nina Skalska-Dziobek, Karolina Chybowska, Maria Naruszewicz, Przemysław Cetnarowski

“…CFTR modulators therapy during the pregnancy was described in a small number of studies, but the current experts statement declares that those drugs are probably safe for the infant, and discontinuing this therapy is connected with an increased risk of pulmonary exacerbation in mothers.   …”
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Epigenetic and Neurological Impairments Associated with Early Life Exposure to Persistent Organic Pollutants by Nathalie Grova, Henri Schroeder, Jean-Luc Olivier, Jonathan D. Turner

“…Together, these first two “hits” produce a quiescent or latent phenotype, most probably encoded in the epigenome, which has become susceptible to a third environmental “hit” in later life. …”
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Protective Effect of Conditioned Medium of Immortalized Human Stem Cells from Exfoliated Deciduous Teeth Against Hair Graying Caused by X-Ray Irradiation via Its Antioxidative Acti... by Yasuhiro Katahira, Eri Horio, Natsuki Yamaguchi, Jukito Sonoda, Miu Yamagishi, Satomi Miyakawa, Fumihiro Murakami, Hideaki Hasegawa, Izuru Mizoguchi, Takayuki Yoshimoto

“…Immunodepletion of HGF or VEGF in the SHED-CM revealed that this inhibition was due to suppression of the generation of reactive oxygen species, which was mainly mediated by HGF and probably VEGF. These results suggest that SHED-CM has protective effects against hair graying via its antioxidative activity.…”
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Knockdown of hexokinase 2 results in a decreased expression level of the glycolytic enzymes PFKP, BPGM, and GPI in RKO cell line by M. S. Fedorova, I. Y. Karpova, A. V. Lipatova, E. A. Pudova, Z. G. Guvatova, D. V. Kochetkov, A. V. Chaika, B. Y. Alekseev, M. V. Kiseleva, A. D. Kaprin, A. V. Kudryavtseva, A. V.  Snezhkina

“…A significant decrease in the expression of PFKP, BPGM, and GPI genes both at the mRNA (5­, 86­, and 93­fold, respectively) and protein (2.5­, 3.5­, and 19­fold, respectively) levels was revealed. Probably, the downregulation of GPI and PFKP is associated with a decrease in the amount of their substrates, glucose­6­phosphate and fructose6­phosphate, under the inhibition of hexokinase 2. …”
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A Laboratory Approach Considering Salinity to Investigate Archie’s Parameters in Deep Shale: A Case Study in Longmaxi Formation, Southern Sichuan by Yanran Li, Xiangui Liu, Changhong Cai, Zhiming Hu, Bo Wu, Ying Mu, Xianggang Duan, Qingxiu Zhang, Shuti Zeng, Jingshu Guo, Zhijin Pu

“…Our cementation factor is lower than that in other studies including (shaly) sandstones, carbonates, and shales, probably due to the extremely low porosity in study area. …”
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Ambient air pollution and carcinogenic activity at three different urban locations by Ivana Jakovljević, Zdravka Sever Štrukil, Gordana Pehnec, Tajana Horvat, Mandica Sanković, Antun Šumanovac, Silvije Davila, Nikolina Račić, Goran Gajski

“…Cancer risk values obtained during the analysis were at an acceptable limit level, which was between 10−6 and 10−4 (values higher than 10−4 indicate high probable health risks).…”
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Effects of Cholecalciferol on Key Components of Vitamin D-Endo/Para/Autocrine System in Experimental Type 1 Diabetes by Anna Mazanova, Ihor Shymanskyi, Olha Lisakovska, Lala Hajiyeva, Yulia Komisarenko, Mykola Veliky

“…We demonstrated that T1D led to a decrease in blood 25OHD, which is probably due to the established downregulation of CYP27A1 and CYP2R1 expression. …”
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Using nasal sprays to prevent respiratory tract infections: a qualitative study of online consumer reviews and primary care patient interviews by Paul Little, Katherine Bradbury, Lucy Yardley, Adam W A Geraghty, Ben Ainsworth, Kate Greenwell, Deb Smith, Laura Dennison, Sian Williamson, James Denison-Day, Fiona Mowbray, Samantha Richards-Hall

“…Study 2 interviewed patients about their reactions to and experiences of a digital intervention that promotes and supports nasal spray use for RTI prevention (reactively: at ‘first signs’ of infection and preventatively: following possible/probable exposure to infection). Interview transcripts were analysed using thematic analysis.Setting Primary care, UK.Participants 407 online customer reviews. 13 purposively recruited primary care patients who had experienced recurrent infections and/or had risk factors for severe infections.Results Both studies identified various factors that might influence nasal spray use including: high motivation to avoid RTIs, particularly during the COVID-19 pandemic; fatalistic views about RTIs; beliefs about alternative prevention methods; the importance of personal recommendation; perceived complexity and familiarity of nasal sprays; personal experiences of spray success or failure; tolerable and off-putting side effects; concerns about medicines; and the nose as unpleasant and unhygienic.Conclusions People who suffer disruptive, frequent or severe RTIs or who are vulnerable to RTIs are interested in using a nasal spray for prevention. …”
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Clonal dissemination of an NDM-2-producing Acinetobacter baumannii ST103 clone resulting in an outbreak in an intensive care unit of a Lebanese tertiary care hospital by Tania Nawfal Dagher, Linda Hadjadj, Fadi Bittar, Fadi Fenianos, Elias Abdo, Jean-Marc Rolain, Charbel Al-Bayssari

“…This study aimed to investigate the molecular mechanism of carbapenem resistance and the clonal relationship of CRAB isolates of a probable outbreak in the intensive care unit (ICU) of Saydet Zgharta University Medical Center, in north Lebanon. …”
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Photocatalytic Mineralization of Organic Acids over Visible-Light-Driven Au/BiVO4 Photocatalyst by Kanlaya Pingmuang, Natda Wetchakun, Wiyong Kangwansupamonkon, Kontad Ounnunkad, Burapat Inceesungvorn, Sukon Phanichphant

“…Photocatalytic results showed that all Au/BiVO4 samples exhibited higher oxalic acid mineralization rate than that of pure BiVO4, probably due to a decrease of BiVO4 band gap energy and the presence of surface plasmon absorption upon loading BiVO4 with Au as evidenced from UV-Vis DRS results. …”
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The difference between young and older ducks: Amino acid, free fatty acid, nucleotide compositions and breast muscle proteome by Tiantian Gu, Mingcai Duan, Li Chen, Yong Tian, Wenwu Xu, Tao Zeng, Lizhi Lu

“…Duck meat has a unique taste and nutritional value, but age probably affects meat quality. In this study, ducks of different ages (60-day-old, D60; 900-day-old, D900) were chosen, and the odor, taste, amino acid, nucleotide, and free fatty acid components of breast meat were evaluated to investigate the differences. …”
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Survival after Locoregional Treatments for Hepatocellular Carcinoma: A Cohort Study in Real-World Patients by Simona Signoriello, Annalisa Annunziata, Nicola Lama, Giuseppe Signoriello, Paolo Chiodini, Ilario De Sio, Bruno Daniele, Giovanni G. Di Costanzo, Fulvio Calise, Graziano Olivieri, Vincenzo Castaldo, Rosario Lanzetta, Guido Piai, Giampiero Marone, Mario Visconti, Mario Fusco, Massimo Di Maio, Francesco Perrone, Ciro Gallo, Giovanni B. Gaeta

“…OS did not significantly differ between RFA and PEI (HR 1.11, 95% CI 0.79–1.57), between surgery and RFA/PEI (HR 0.95, 95% CI 0.64–1.41) and between TACE/TAE and RFA/PEI (HR 0.88, 95% CI 0.66–1.17). 5-year OS probabilities were 0.14 for RFA, 0.18 for PEI, 0.27 for surgery, and 0.15 for TACE/TAE. …”
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Aqueous foams in microgravity, measuring bubble sizes by Pasquet, Marina, Galvani, Nicolo, Pitois, Olivier, Cohen-Addad, Sylvie, Höhler, Reinhard, Chieco, Anthony T., Dillavou, Sam, Hanlan, Jesse M., Durian, Douglas J., Rio, Emmanuelle, Salonen, Anniina, Langevin, Dominique

“…The temporal evolution of the average bubble radii deduced from DTS and of the same average radii of the bubbles measured at the sample surface is the same (to a factor probably close to one) throughout the coarsening. Finally, ground experiments were performed to compare bubble size distributions in a bulk wet foam and at its surface at times so short that diffusive gas exchange is insignificant. …”
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Incidence and outcomes of neonatal group B streptococcal sepsis in Qatar-a multicentre study by Sajid Salim Thyvilayil, Anvar Paraparambil Vellamgot, Khalil Salameh, Sudheer Babu Kurunthattilthazhe, Abdurahiman Elikkottil, Liliana Llerena Dominguez, Dhanya Banarjee

“…The relatively high incidence of EOGBSS probably reflects the high rate of carrier state among pregnant mothers. …”
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miR-125b differentially impacts mineralization in dexamethasone and calcium-treated human mesenchymal stem cells by Virginie Joris, Elizabeth R. Balmayor, Martijn van Griensven

“…We showed that miR-125b mimicking differentially modulated the expression of the miR-199a/214 cluster, probably via STAT3/miR-199a/214 and p53/miR-214 pathways. …”
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