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381
INBRX-120, a CD8α-targeted detuned IL-2 that selectively expands and activates tumoricidal effector cells for safe and durable in vivo responses
Published 2023-01-01“…Preclinical safety, as well as pharmacodynamic (PD) and PK profiling was carried out in non-human primates.Results INBRX-120 effectively expanded and enhanced the cytotoxic capacity of CD8 T cells and natural killer cells towards tumor cells without affecting regulatory T cells in vitro and in vivo. …”
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382
Préférence manuelle chez les gibbons
Published 2016-01-01“…Nous discuterons l’importance de la complexité de la tâche lorsque l’on teste la latéralité manuelle, les pressions de sélection qui pourraient avoir agi spécifiquement sur les hylobatidés hautement arboricoles, ainsi que les facteurs qui pourraient expliquer la différence entre les données de latéralité chez des populations de primates sauvages versus primates captifs.Nous remercions les administrateurs et les gardiens de zoos qui ont contribué à la collecte de données. …”
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383
Update on a Pharmacokinetic-Centric Alternative Tier II Program for MMT—Part II: Physiologically Based Pharmacokinetic Modeling and Manganese Risk Assessment
Published 2012-01-01“…., adult, pregnant, lactating, and neonatal rats, nonhuman primates, and adult, pregnant, lactating, and neonatal humans) and relevant risk assessment applications. …”
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384
Estimation de la densité par comptage des nids des Bonobos (Pan paniscus) dans la région de Bolobo des localités de Nkala et Embirima, République Démocratique du Congo : résultats...
Published 2014-03-01“…In this study, we researched the bonobos distribution, Pan paniscus (Pongidae, Primates), in their origin location from Bolobo. We determined the densities of the populations of bonobos in the mosaics of forests intersected with savannas in this area. …”
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385
Neural correlates of executive control in the avian brain.
Published 2005-06-01“…Executive control, the ability to plan one's behaviour to achieve a goal, is a hallmark of frontal lobe function in humans and other primates. In the current study we report neural correlates of executive control in the avian nidopallium caudolaterale, a region analogous to the mammalian prefrontal cortex. …”
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386
Revisiting Capuchin Monkeys (Cebus capucinus) and the Ancient Maya
Published 2014-02-01“…Two genera of nonhuman primates, howler monkeys (Alouatta palliata and A. pigra) and spider monkeys (Ateles geoffroyi) currently reside throughout the area inhabited by the modern Maya. …”
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387
Nonhematopoietic Variants of Erythropoietin in Ischemic Stroke: Need for Step-Wise Proof-of-Concept Studies
Published 2010-01-01“…In view of the potential clinical use of Neuro-EPO, stringent proof-of-concept studies are urgently needed to define (1) how intranasally delivered Neuro-EPO reaches the brain, (2) which concentrations are achieved in the ischemic and nonischemic brain tissue of rodents and nonhuman primates, and (3) which are the mechanisms via which Neuro-EPO protects from injury. …”
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388
Sensibilisation à l’environnement d’un collège alsacien et d’une école malgache
Published 2015-12-01“…Three annual visits to the zoo allow to children (1) to enhance their understanding of the fauna and flora, this aspect being completed by a personal bibliography produced by children; (2) to introduce notions on the phenotypic classification of primates by observing animals and the help of simple arrays of determining criteria ; (3) to improve their ecological awareness with tangible and common examples like the deforestation in Madagascar or the invasive species introduction, pupils are invited to think about these subjects and to suggest theoretical solutions ; (4) to observe the interspecific behavioral differences and the sexual hierarchy of lemurs using simple ethological observations ("all occurrences sampling" methods) of several species.…”
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389
Surrounded by invaders: marmoset conservation challenges in Brazilian Atlantic Forest fragments
Published 2025-01-01“…Abstract Fragmented landscapes resulting from Atlantic Forest loss can facilitate biological invasions by certain species of the Callithrix genus. These primates demonstrate high invasion potential, spreading across Brazil, competing for resources, and even hybridizing with C. aurita, the only native species to Rio Doce State Park (RDSP). …”
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390
Does SIRT-1 Mediate Calorie Restriction and Prolong Life? – A Mini Review
Published 2014-09-01“…Calorie restriction is the only intervention proved to prolong both average and maximum lifespan in yeast, worms, fish, rodents and possibly primates. Not only does the regimen prolong life, but it also reduces the incident of numerous age-related diseases like diabetes, atherosclerosis or cancer and slows down ageing. …”
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391
Good and Justice in the Context of Environmental Ethics
Published 2022-03-01“…The article explores issues about the origin of morality, as well as some ideas about the moral status of attitudes among primates. More important conclusions are that ethics and environmental knowledge must be developed in cooperation in order to explain and form moral consciousness, a new type of ethos that does not allow indifference to the environment in human interaction with it, and that moral considerations should contain not only prescriptions for due human behavior in human society, but also obligations to non-human inhabitants of nature or to the environment. …”
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392
Propithecus verreauxi demography spanning 40 years at Bezà Mahafaly Special Reserve, southwest Madagascar
Published 2025-01-01“…Lemurs, the island’s endemic primates, exhibit a distinctive array of biological, behavioral and demographic traits. …”
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393
Aux sources de la spécialisation hémisphérique cérébrale du langage : l'intérêt de l'IRM anatomique chez le babouin
Published 2015-03-01“…Au regard de la proximité phylogénétique des primates humains et non humains, les études sur les asymétries des systèmes de communication de nos cousins les primates peuvent nous aider à détecter les précurseurs éventuels de cette spécialisation hémisphérique du langage chez notre ancêtre commun. …”
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394
Le lymphosarcome fausse les résultats du test de la tuberculose effectué sur le sang
Published 2015-03-01“…La législation européenne (directive 92/65/CEE, article 14 et annexe B) impose, pour les primates non humains, un dépistage annuel de la tuberculose (Mycobacterium tuberculosis). …”
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395
Traitement d’un lymphome agressif chez un babouin naturellement infecté par STLV-1
Published 2016-01-01“…STLV-1 est l’homologue simien de HTLV-1 et cause aussi des ATLL chez les primates non humains. Au cours du contrôle sanitaire annuel dans notre colonie de Papio anubis naturellement infectés par STLV-1 (n=45), une femelle de 9 ans fut identifiée comme présentant des troubles respiratoires, un amaigrissement prononcé, un nombre de lymphocytes supérieur à 1010/L, des métastases pulmonaires et des lésions de la peau, similaires à celles qui sont observées chez les patients souffrant d’ATLL. …”
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396
Tsidy, Repahaka sy Fotsife: 15 years research on nocturnal lemurs in the Ankarafantsika National Park, Madagascar
Published 2011-10-01“…The goal is to enhance our knowledge on the adaptation and evolution of a previously neglected group of primates, the nocturnal lemurs, and to contribute to their conservation. …”
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397
Production de savoir et dynamique pédagogique ingénieuse. Le cas particulier de « l’Ecole de Tours »
Published 2012-04-01“…Depuis les années ‘80, les enseignants-chercheurs du département des sciences de l’éducation et de la formation de l’Université de Tours développent une pédagogie universitaire de formation par alternance comme voie différente pour apprendre et se former. « L’Ecole de Tours » est fondée sur le primat de l’expérience et celui de la production de savoir, renversant l’ordonnancement classique de la formation, mais convergeant vers l’abstraction avec les mêmes exigences de savoirs rigoureux conceptuels et méthodologiques. …”
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398
Acquisition of similar properties by filters in the same stream of a multistream convolutional neural network
Published 2025-01-01“…In the visual cortex of primates, adjacent neurons often respond to the same visual submodality, such as color or orientation, and have a similar preferred orientation or preferred color. …”
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399
Gestion en métapopulation de Propithecus coronatus: une approche originale et multidisciplinaire pour la conservation d’une espèce en danger à Madagascar
Published 2011-10-01“…A conservation project has been established in partnership between GERP (Groupe d’Etude et de Recherche sur les Primates de Madagascar), The Aspinall Foundation Madagascar and the European Endangered species Programme (EEP) following the discovery of isolated crowned sifaka populations along the central highlands of Madagascar. …”
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400
灵长类浅说
Published 1982-01-01“…<正> 环顾国际兽类学研究工作的动态,灵长类(Primates)的研究已经越来越受到国际动物学界的重视,目前已成为当代兽类学研究的中心问题之一。分析其受重视的原因有二: 1、研究灵长类,可以为人类起源于猿类的假说提供更多和更充分的论据。 …”
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