Frailty and the Risk of Polypharmacy in the Older Person: Enabling and Preventative Approaches by Martin C. Nwadiugwu

“…Appropriate medication reconciliation in this population with useful prescribing tools (Beers and START/STOPP criteria) to minimize polypharmacy and to provide alternative prescriptive intervention could go alongside primary care to reduce the extent of frailty and polypharmacy. …”
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Incidence of Severe Pain in Newly Diagnosed Ambulatory Patients with Stage IV Cancer by Thomas Isaac, Sherri O Stuver, Roger B Davis, Susan Block, Jane C Weeks, Donna L Berry, Saul N Weingart

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Antibiotic-Resistant Escherichia coli in Women with Acute Cystitis in Canada by Warren J McIsaac, Rahim Moineddin, Christopher Meaney, Tony Mazzulli

“…While resistance is increasing, there are no recent Canadian estimates from a primary care setting to guide prescribing decisions.…”
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The Training of Professionals in Medical Universities and the Social Determinants of Health by Miguel Ángel Serra Valdés

“…The primary care reform based on the principles of universal access, equity and social justice proposed by the World Health Organization is an essential response to the challenges presented by the social determinants of health. …”
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Approach to: the Patient with a Palpable Breast Mass by Rose Di Ioia

“…Palpable breast masses are common reasons for presenting to the primary care or emergency clinic setting. Although most palpable masses are benign in etiology, the possibility of malignancy exists and may be anxiety-inducing to patients. …”
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Structured follow-up pathway to support people after transient ischaemic attack and minor stroke (SUPPORT TIA): protocol for a feasibility study and process evaluation by Grace M Turner, Melanie Calvert, Sue Jowett, Robbie Foy, Jonathan Mant, Sarah Tearne, Lou Atkins, Rachael Jones, Smitaa Patel, Phillip Collis

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The availability and distribution of health services and resources across different regions in Afghanistan by Nelly Hegazy, Sherif El Deeb, Marwa Rashad Salem, Jerome A. Shaguy, Ramesh Nassery Mohammed, Abdullah Khawari, Jamshed Tanoli, Alaa Abouzeid, Alaa Abouzeid

“…Outpatient services for primary care are notably prevalent in the Northeastern, Southeastern, Southern, Eastern, and Northern region, conversely, the Capital and Central Highland regions demonstrate the lowest provision of primary care services. …”
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Ten proposed measures to improve vaccination: Health care providers’ perspectives on promoting the vaccination intake of children with special healthcare needs in China by Xiang Guo, Tianxing Feng, Meiyi Chen, Xuran Zhao, Xiangshi Wang, Yanling Ge, Zhonglin Wang, Zhuoying Huang, Mei Zeng

“…A purposive sampling strategy was used to recruit interviewees including primary care providers, paediatricians and immunisation programme administrators. …”
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Trends in clinical encounters and management for infertility among women attending Australian general practice: a national longitudinal study using MedicineInsight, 2011 to 2021 by Alice R Rumbold, Michael Davies, Danielle Mazza, Jacqueline Boyle, Vivienne Moore, Renae C Fernandez, Luke E Grzeskowiak

“…These findings support the development of clinical practice guidelines to enhance standardised and equitable approaches towards the management of infertility in primary care.…”
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Approaches to implementing and financing primary health care in Kenya: a case of seven counties by Janette Karimi, Salim Hussien, Elizabeth Wangia, Mercy-Irene Kimani, Mohamud Mohamed, Melissa Wanda, Rosemarie Muganda, Rachel Ndirangu, Daniel Mwai, Mercy Wanjala, Fadhila Richter

“…All participating counties adopted Sub-County Health Management Teams (SCHMTs) as the MDTs due to staffing limitations at primary care facilities consequently inhibiting the capacity for effective MDT engagement. …”
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What are the perceptions and experiences of adults using mobile applications for self-management in diabetes? A systematic review by Benedict Hayhoe, Azeem Majeed, Geva Greenfield, Ana Luísa Neves, Henock B Taddese, Kalthum Patail, Hui Hsuan Pai

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Mendelian Randomisation Study of Childhood BMI and Early Menarche by Hannah S. Mumby, Cathy E. Elks, Shengxu Li, Stephen J. Sharp, Kay-Tee Khaw, Robert N. Luben, Nicholas J. Wareham, Ruth J. F. Loos, Ken K. Ong

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Early weight gain after stopping smoking: a predictor of overall large weight gain? A single-site retrospective cohort study by Alexandra Pankova, Eva Kralikova, Kamila Zvolska, Lenka Stepankova, Milan Blaha, Petra Ovesna, Paul Aveyard

“…We examined whether early large postcessation weight gain predicts overall large weight gain.Design Retrospective cohort study.Setting Primary care setting—smoking cessation centre in Prague, Czech Republic.Participants Out of 3537 patients treated between 2005 and 2013, 1050 were continuous abstainers (verified by carbon monoxide measurement) at 1-year follow-up and formed the cohort of the current report. 48.7% were women (n=511) with the mean age of 46 (±14.4) years.Methods In this retrospective cohort study, all patients underwent usual tobacco dependence treatment using evidence-based methods. …”
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Plasma Iron Levels at Early Breast Cancer Diagnosis Are Associated With Development of Secondary Metastases: A Single-Center Retrospective Cohort Study by Jasmine De Troy, Sarah-Maria Fendt, Sigrid Hatse, Patrick Neven, Ann Smeets, Annouschka Laenen, Hans Wildiers

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Turning green: the impact of changing to more eco-friendly respiratory healthcare – a carbon and cost analysis of Dutch prescription data by Evelyn A Brakema, johan Kooistra, Niels Chavannes, Paul Hagedoorn, Pieter ten Have, Peter van Hal, Iris Wichers, Pauline de Heer, Hans C Ossebaard

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School performance gap between non-immigrant and second-generation immigrant children in Sweden—time trends and contributing factors by Kenta Okuyama, Sara Larsson Lönn, Ardavan M. Khoshnood, Ardavan M. Khoshnood, Shervin Assari, Shervin Assari, Shervin Assari, Shervin Assari, Jan Sundquist, Jan Sundquist, Kristina Sundquist, Kristina Sundquist

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Prevalence of potentially inappropriate prescribing in a subpopulation of older European clinical trial participants: a cross-sectional study by Manuel R Blum, Patricia M Kearney, Rose Galvin, Christine Baumgartner, Anette Van Dorland, Stephen Byrne, Nicolas Rodondi, Simon P Mooijaart, Carol Sinnott, Rosalinde K E Poortvliet, Jacobijn Gussekloo, David O Riordan, Carole Elodie Aubert, Kieran A Walsh, Robert S Du Puy, J Wouter Jukema, Vera McCarthy, Elaine K Walsh, Tinh-Hai Collet, Olaf M Dekkers

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Randomised trial of coconut oil, olive oil or butter on blood lipids and other cardiovascular risk factors in healthy men and women by Stephen J Sharp, Kay-Tee Khaw, Robert Luben, Nita G Forouhi, Leila Finikarides, Islam Afzal, Marleen Lentjes

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Associations of maternal PM2.5 exposure with preterm birth and miscarriage in women undergoing in vitro fertilization: a retrospective cohort study by Miaoxin Chen, Qiaoyu Chen, Gengze Liao, Chunyan Sun, Cong Liu, Xia Meng, Wentao Li, Andong Qiu, Orhan Bukulmez, Haidong Kan, Feng Wang, Lap Ah Tse, Xiaoming Teng

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Malignant Hyperthermia and Idiopathic HyperCKemia by Pashtoon Murtaza Kasi

“…Anesthesiologists and critical care intensivists as well as primary care physicians should keep this in mind when seeing patients with asymptomatic hyperCKemia and potentially inform them about the possibility of developing MH if exposed to triggering agents. …”
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