Improving the diagnostic accuracy of referrals for papilloedema (DIPP) study: protocol for a mixed-methods study by Luke Bennetto, Beth Stuart, Jonathan Benger, Matthew J Ridd, Helen Bolton, William Hollingworth, Michael Bowen, Amar Shah, Samuel William David Merriel, Alyson Huntley, Victoria Wilson, Maria Theresa Redaniel, Paul Roy, Denize Atan, Frank Moore, Olivia Skrobot, Mary-Ann Sherratt, Marcia Lucraft, Christina Stokes

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Exploring the barriers to cervical screening and perspectives on new self-sampling methods amongst under-served groups by Stephanie Gillibrand, Helen Gibson, Kelly Howells, Sean Urwin, Jennifer C. Davies, Emma J. Crosbie, Caroline Sanders

“…Methods We draw on three integrated theoretical frameworks (access to primary care services, intersectional and feminist perspectives) to examine participants’ barriers to screening and views toward self-sampling methods. …”
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The association of HIV status and depressive symptoms in the Ndlovu Cohort study by Li Xiang Y. den Boer, Karine Scheuermaier, Hugo A. Tempelman, Roos E. Barth, Walter L. J. M. Devillé, Roel A. Coutinho, Diederick E. Grobbee, Francois Venter, Alinda G. Vos-Seda, Kerstin Klipstein-Grobusch

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The chronic need to improve the management of pain by Eldon Tunks

“…Fear of a College audit resulting in the loss of their medical licence was cited by 10% of primary care physicians. When asked what obstacle hindered their use of strong opioid analgesics, an unexplained 10% of palliative care doctors and 14% of primary care doctors answered "nothing in particular".…”
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Diagnostic pathways for breast cancer in 10 International Cancer Benchmarking Partnership (ICBP) jurisdictions: an international comparative cohort study based on questionnaire and... by David Weller, Usha Menon, Alina Zalounina Falborg, Henry Jensen, Andriana Barisic, Anne Kari Knudsen, David H Brewster, Victoria Cairnduff, Eva Grunfeld, Elizabeth Harland, Mats Lambe, Rebecca-Jane Law, Yulan Lin, Martin Malmberg, Donna Turner, Richard D Neal, Victoria White, Samantha Harrison, Peter Vedsted, Una MacLeod, Conan Donnelly, Anna Gavin, Jon Emery, Oliver Bucher, Jatinderpal Kalsi, Chantelle Anandan, Evangelia Ourania Fourkala, Therese Kearney, Marie-Louise Essink-Bot, Sigrun Saur Almberg, Breann Hawryluk, Jacqueline Kelly, Jackie Boylan, Jan Willem Coebergh, David Brewster, Stefan Bergström, Victoria Hammersley, Rebecca Bergin, Alina Zalounina Falborg, Andriana Barisi, Kerry Moore, Maria Rejmyr Davis

“…Data were supplemented by feedback from their primary care physicians (PCPs), cancer treatment specialists and available registry data.Primary and secondary outcome measures Patient, primary care, diagnostic and treatment intervals.Results Overall, 56% of women reported symptoms to primary care, with 66% first noticing lumps or breast changes. …”
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Response to: Comment on “Pain Perception of the First Eye versus the Second Eye during Phacoemulsification under Local Anesthesia for Patients Going through Cataract Surgery: A Sys... by Chuying Shi, Benny Zee

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Inequalities in physical comorbidity: a longitudinal comparative cohort study of people with severe mental illness in the UK by Tim Doran, Darren M Ashcroft, Evangelos Kontopantelis, David Reeves, Siobhan Reilly, Claire Planner, Ivan Olier, Linda Gask

“…Objectives Little is known about the prevalence of comorbidity rates in people with severe mental illness (SMI) in UK primary care. We calculated the prevalence of SMI by UK country, English region and deprivation quintile, antipsychotic and antidepressant medication prescription rates for people with SMI, and prevalence rates of common comorbidities in people with SMI compared with people without SMI.Design Retrospective cohort study from 2000 to 2012.Setting 627 general practices contributing to the Clinical Practice Research Datalink, a UK primary care database.Participants Each identified case (346 551) was matched for age, sex and general practice with 5 randomly selected control cases (1 732 755) with no diagnosis of SMI in each yearly time point.Outcome measures Prevalence rates were calculated for 16 conditions.Results SMI rates were highest in Scotland and in more deprived areas. …”
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Using the Medical Research Council Framework for the Development and Evaluation of Complex Interventions in a Theory-Based Infant Feeding Intervention to Prevent Childhood Obesity:... by Rajalakshmi Lakshman, Simon Griffin, Wendy Hardeman, Annie Schiff, Ann Louise Kinmonth, Ken K. Ong

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What Moves Them? Active Transport among Inhabitants of Dutch Deprived Districts by Carla Saris, Stef Kremers, Patricia Van Assema, Cees Hoefnagels, Mariël Droomers, Nanne De Vries

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Do doctors and other healthcare professionals know overdiagnosis in screening and how are they dealing with it? A protocol for a mixed methods systematic review by Ann Van den Bruel, An De Sutter, Stefan Heytens, Veerle Piessens, Ann Van Hecke

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Factors associated with assertiveness among Japanese community pharmacists: a cross-sectional study by Mitsuaki Ishii, Sachiko Ozone, Shoichi Masumoto, Tetsuhiro Maeno

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South Asian women’s lived experiences of health care after disclosure of family violence: a qualitative meta-synthesis review by Surriya Baloch, Elizabeth McLindon, Mohajer Hameed, Kelsey Hegarty

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Effectiveness of a specialist palliative home care nurse–patient consultation followed by an interprofessional telephone case conference compared with usual care among patients wit... by Judith Dams, Hans-Helmut König, Tim Friede, Nils Schneider, Stephanie Stiel, Martin Scherer, Silke Böttcher, Gabriella Marx, Ingmar Schäfer, Nadine Janis Pohontsch, Hendrik van den Bussche, Friedemann Nauck, Michael Freitag, Eva Hummers, Tina Mallon, Franziska Schade, Manuel Zimansky, Thomas Asendorf, Christiane A Mueller

“…Introduction Progressive chronic, non-malignant diseases (CNMD) like congestive heart failure (CHF), chronic obstructive pulmonary disease (COPD) and dementia are of growing relevance in primary care. Most of these patients suffer from severe symptoms, reduced quality of life and increased numbers of hospitalisations. …”
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Associations between prior healthcare use, time to diagnosis, and clinical outcomes in inflammatory bowel disease: a nationally representative population-based cohort study by Alex Bottle, Sonia Saxena, Richard C G Pollok, Jonathan Blackwell, Irene Petersen, Hanna Creese, Nishani Jayasooriya, Richard CG Pollok

“…We used multivariable Cox regression to examine the association of primary care consultation frequency (n=1, 2, >2), annual consultation intensity, hospitalisations for gastrointestinal symptoms, and time to diagnosis with a range of key clinical outcomes following diagnosis.Results We identified 2645 incident IBD cases (CD: 782; UC: 1863). …”
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Study protocol for a pragmatic randomised controlled trial of comparing enhanced acceptance and commitment therapy plus (+) added to usual aftercare versus usual aftercare only, in... by Imran Khan, Stephanie J. C. Taylor, Clare Robinson, Elisavet Moschopoulou, Paul McCrone, Liam Bourke, Mohamed Thaha, Kamaldeep Bhui, Derek Rosario, Damien Ridge, Sheila Donovan, Ania Korszun, Paul Little, Adrienne Morgan, Olivier Quentin, Rebecca Roylance, Peter White, Trudie Chalder

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Multimorbidity is associated with risk of incident venous thromboembolism – A nationwide proof-of-concept study by Jonatan Ahrén, MirNabi Pirouzifard, Björn Holmquist, Jan Sundquist, Kristina Sundquist, Bengt Zöller

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Reasons why osteoarthritis predicts mortality: path analysis within a Cox proportional hazards model by George Peat, Martin J Thomas, Milica Blagojevic-Bucknall, Ross Wilkie, Simran Singh Parmar, Diane Smith, Bethany Jane Seale, Gemma Mansell

“…OA was defined by primary care consultation and moderate-to-severe pain interference in daily life. …”
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General practice residents’ perspectives on their professional identity formation: a qualitative study by Mattijs E Numans, Vera Nierkens, Yvonne Steinert, Pieter C Barnhoorn, Anneke WM Kramer, Walther NKA van Mook

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MOUD 2.0: a clinical algorithm and implementation evaluation protocol for sublingual and injectable buprenorphine treatment of opioid use disorder by Brandon L. Joa, Eric N. Fung, Michael S. Weinstein, Lara C. Weinstein, Lara C. Weinstein

“…BackgroundPrimary care is the initial contact point for most patients with opioid use disorder (OUD) but lacks tools for guiding treatment. …”
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COVID-19 health information needs of older adults from ethnic minority groups in the UK: a qualitative study by Jackie A Cassell, Laura J Hughes, Elizabeth Ford, Priyamvada Paudyal, Kavian Kulasabanathan, Jo Armes, Rebecca Sharp, Saliha Majeed-Hajaj, Emily Skinner, Naresh Khapangi Magar, Debbie Isobel Keeling

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