25 0H Vitamin D Levels in Pregnant Females: The Hidden Time Bomb by Fatima Tuz Zuhra, Mehnaz, Noreen Atzaz, Shabana, Asma Iqbal, Sami Saeed

“… Objective: To assess and correlate changes in vitamin D levels in three trimesters of pregnancy. Material and methods: This longitudinal study was conducted in collaboration with the Gynecology & Obstetric and Pathology department of Fauji foundation hospital, Rawalpindi. …”
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A Rare Case of Post-Partum Hemorrhage with Refractory Thrombotic Microangiopathy, and Hepatic Infarction: A Diagnostic Dilemma with High Mortality by Naved Yousuf Hasan, Asiah Salem Rugaan, Noha Ahmed Mohamed Ali, Masood Iqbal

“…The patient developed a life-threatening spectrum of thrombotic microangiopathy which is known to result in pregnancy from eclampsia, pre-eclampsia, thrombotic thrombocytopenic purpura, typical and atypical hemolytic uremic syndrome, and hemolysis, elevated liver enzymes, low platelets syndrome and in non-pregnant patients with a wide differential diagnosis. …”
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Why are women still leaving academic medicine? A qualitative study within a London Medical School by Christopher J Peters, Lesley Regan, Victoria Salem, Clare Lloyd, Dhruti Hirani

“…Thematic analysis was performed on the transcribed conversations.Participants and setting Nine women physicians who completed a postgraduate degree (MD or PhD) at a large London Medical School and Academic Health Sciences Centre, Imperial College London, but did not go on to pursue a career in academic medicine.Results Influences to leave clinical academia were summarised under eight themes—career intentions, supervisor support, institutional human resources support, inclusivity, work–life balance, expectations, mentors and role models, and pregnancy and maternity leave.Conclusion The women in our focus group reported several factors contributing to their decision to leave clinical academia, which included lack of mentoring tailored to specific needs, low levels of acceptance for flexible working to help meet parental responsibilities and perceived explicit gender biases. …”
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Sonographic Evaluation of the Obstetric Causes of Vaginal Bleeding During the First Trimester by Naveen Reddy Bandi, Ranjan Nayak Soumya, Jena Satyaswarup, Sahu Niranjan, Das Somadatta

“…The common causes are all types of abortions, including molar and ectopic pregnancies. The aim is to evaluate the obstetric causes of vaginal bleeding during the first trimester. …”
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Diffuse Ectopic Deciduosis Imitating Peritoneal Carcinomatosis with Acute Abdomen Presentation: A Case Report and Literature Review by Pavel Sorokin, Andrei Nikiforchin, Aleksandr Panin, Aleksandr Zhukov, Vadim Gushchin, Mark Kurtser

“…During pregnancy, decidual tissue can occur beyond the endometrium, predominantly on the surface of the uterus, fallopian tubes, and ovaries. …”
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Combined Raman Spectroscopy and Digital Holographic Microscopy for Sperm Cell Quality Analysis by A. De Angelis, S. Managò, M. A. Ferrara, M. Napolitano, G. Coppola, A. C. De Luca

“…To date, morphology, motility, and concentration have been used as key parameters to establish the sperm normality and achieve pregnancy both in natural and in assisted fecundation. …”
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Fatal Postpartum Hemorrhage in a Patient with Niemann-Pick Disease Type B by Atakan Tanacan, Abdullah Yalcin, Canan Unal, Seda Banu Akinci, Mehmet Sinan Beksac

“…The patient concealed her disease from her family and obstetricians during her pregnancy, and her NPD B diagnosis was revealed during her stay in ICU while searching for the cause of the splenectomy and severe bleeding. …”
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Missed Opportunities for Prevention of Perinatal Transmission of Hepatitis B: A Retrospective Cohort Study by Julie van Schalkwyk, Melica Nourmoussavi, Andrea Massey, Reka Gustafson, Elizabeth Brodkin, Martin Petric, Mel Krajden, Simon Dobson, Jane Buxton, Mark Bigham, Neora Pick, Richard Schreiber, Christopher H Sherlock, Deborah Money, Eric M Yoshida

“…Recent literature suggests that antiviral treatment during pregnancy when maternal HBV DNA levels are elevated can further decrease vertical transmission. …”
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Challenges in Assessing Outcomes among Infants of Pregnant HIV-Positive Women Receiving ART in Uganda by Barbara Castelnuovo, Frank Mubiru, Ivan Kalule, Shadia Nakalema, Agnes Kiragga

“…Two of the mothers of the 4 HIV-positive infants were ART-naïve at the time of pregnancy. We report very low documented HIV transmission comparable with those reported in clinical trials settings; however, demonstrating the efficacy of Option B-plus in terms of averted transmission in routine settings is challenging since high proportion of infants do not have documented HIV tests.…”
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Risk Factors for Preterm Labor in Pregnant Women from Ciego de Ávila Municipality by Silvia Estelbina Retureta Milán, Lainys María Rojas Álvarez, Marta Estelbina Retureta Milán

“…<br /><strong>Results:</strong> the factors most associated with preterm labor were history of preterm delivery and previous abortion, low maternal weight at the first prenatal visit, height less than 150 cm, poor or excessive weight gain during pregnancy, smoking, vaginal and urinary infections, multiple gestations and uterine conditions.…”
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Class-Specific Histone Deacetylase Inhibitors Promote 11-Beta Hydroxysteroid Dehydrogenase Type 2 Expression in JEG-3 Cells by Katie L. Togher, Louise C. Kenny, Gerard W. O’Keeffe

“…Placental 11β-HSD2 is known to be reduced in a number of adverse pregnancy complications, possibly through an epigenetic mechanism. …”
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A Case of Ruptured Exophytic Uterine Artery Pseudoaneurysm without Specific Risk Factors That Manifested Seven Days after Vaginal Delivery by Masatake Toshimitsu, Takayuki Iriyama, Jiro Sato, Osamu Abe, Mari Ichinose, Seisuke Sayama, Takahiro Seyama, Kenbun Sone, Keiichi Kumasawa, Yutaka Osuga

“…A uterine artery pseudoaneurysm (UAP) is a life-threatening complication during pregnancy and postpartum. Early diagnosis of exophytic UAP rupture is difficult due to the absence of vaginal bleeding. …”
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Clinical Scoring for Diagnosis of Acute Lower Abdominal Pain in Female of Reproductive Age by Kijja Jearwattanakanok, Sirikan Yamada, Watcharin Suntornlimsiri, Waratsuda Smuthtai, Jayanton Patumanond

“…The developed clinical score is comprised of (1) guarding or rebound tenderness, (2) pregnancy, (3) sites of abdominal tenderness, (4) leukocytosis, (5) peripheral neutrophils ≥75%, and (6) presence of diarrhea. …”
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Umbilical Artery Thrombosis with Associated Acute and Severe Fetal Growth Restriction and Transient Severe Protein S Deficiency: Report of a Case with Prenatal Ultrasound Diagnosis... by Ali Alhousseini, Sunil Jaiman, Edgar Hernandez-Andrade, Salam Zeineddine, Faisal Qureshi, Suzanne M. Jacques

“…Thrombosis of one of the umbilical arteries can be associated with adverse pregnancy outcomes such as stillbirth and severe intrauterine growth restriction (IUGR). …”
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The Effect of Different Doses of Intraamniotic Digoxin on the Timing of Fetal Demise in Second Trimester Medical Abortions by Gulsah Aynaoglu Yildiz, Ragip Atakan Al

“… OBJECTIVES: The World Health Organization recommends feticide for termination of pregnancy after 20 weeks of gestation, and the Royal College of Obstetricians & Gynecologists after 21 weeks and 6 days. …”
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Live Birth from the Transfer of a Severely Fragmented Embryo Observed by Morphokinetics by S. Lahav-Baratz, I. Blais, M. Koifman, D. Ishai, Z. Wiener-Megnazi, G. Peer, M. Dirnfeld

“…A 32-year-old patient underwent 2 IVF cycles without achieving pregnancy. In the first cycle, 2 embryos with fragmentation were transferred; in the second, all embryos were fragmented and no embryo transfer was performed. …”
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Comprehensive review of preclinical evaluation strategies for COVID-19 vaccine candidates: assessing immunogenicity, toxicology, and safety profiles by Delaram Doroud, Mojtaba Daneshi, Fatemeh Kazemi-Lomedash, Zohre Eftekhari

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Influence of mode of delivery on maternal and fetal outcomes in patients with preterm prelabor rupture of membranes by K. S. Midhuna, Umadevi Vavaldas, Sarada Kandhichetty

“…Preterm prelabor rupture of membranes (PPROM) early diagnosis and intervention decide the further fate of pregnancy. Maternal and fetal outcome in PPROM is very important to decrease maternal and child mortality and for better management and prevention of complications. …”
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New Insights in Genetic Cholestasis: From Molecular Mechanisms to Clinical Implications by Eva Sticova, Milan Jirsa, Joanna Pawłowska

“…In addition to familial intrahepatic cholestasis, partial defects in ATP8B1, ABCB11, and ABCB4 predispose patients to drug-induced cholestasis and intrahepatic cholestasis in pregnancy. This review summarises the current knowledge of the clinical manifestations, genetics, and molecular mechanisms of these diseases and briefly outlines the therapeutic options, both conservative and invasive, with an outlook for future personalised therapeutic strategies.…”
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A comparison of different cryoprotectant solutions and thawing methods for cryo­preservation of embryos of mice and rats by T. N. Igonina, E. Yu. Brusentsev, I. N. Rozhkova, V. A. Naprimerov, S. Ya. Amstislavsky

“…Cleavage-stage embryos of ICR mice, GC rats, and OXYS rats were collected on Day 3 of pregnancy and frozen in plastic straws according to a standard protocol. …”
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