Pharmacist-led DE-eSCALation of opioids post-surgical dischargE (DESCALE) – A multi-centre, non-randomised, feasibility study protocol [version 2; peer review: 1 approved, 2 approv... by Ellie Santer, Julie H Hedayioglu, Vanessa J Short, Sabina Hulbert, Emma L Veale, Melanie Rees-Roberts, Johanna Theron

“…Methods DESCALE is a multicentre, non-randomised, pragmatic feasibility study. Participants aged ≥18 years who have undergone a surgical procedure at a single NHS trust in Southeast England and discharged with opioids and without a history of long-term opioid use, cancer diagnosis or study contraindications will be offered a Medicines Use Review (MUR) within 7-10 days of discharge. …”
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Interventions to improve media coverage of medical research: a codesigned feasibility and acceptability study with Australian journalists by Brooke Nickel, Ray Moynihan, Alexandra Barratt, Kirsten J McCaffery, Loai Albarqouni, Tessa Copp, Thomas Dakin, Liam Mannix

“…This study aimed to codesign and assess the feasibility of a multicomponent training intervention for journalists in Australia.Design A small pragmatic feasibility study using a pre- and postdesign.Setting 90 min online workshop.Participants Eight journalists currently working in Australia, recruited through the study’s journalist advisor and existing contacts of the researchers.Intervention The training intervention covered a range of topics, including study designs, conflicts of interest, misleading medical statistics, population screening and overdiagnosis. …”
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Trabeculectomy versus stepwise treatment for breaking the attack of acute primary angle closure in patients with long attack duration: study design and protocol for a multicentre r... by Jing Jiang, Qing Zhang, Bo Qu, Chao Dai, Mingguang He, Ye Zhang, Ning-Li Wang, Shuning Li, Guangxian Tang, Su Jie Fan, Zhi Li, Chi Liu, Xinqi Chang, Yanyan Cheng

“…Since prompt and effective treatment is pivotal in preserving visual function as well as avoiding APAC-induced blindness, direct trabeculectomy may largely benefit long-attacking patients with APAC in China.Purpose The Long-Attacking Acute Angle Closure study aims to compare long-term visual function and safety after different initial treatment strategies: direct surgery (trabeculectomy) or stepwise protocol for patients with APAC with attack duration longer than 72 hours.Methods and analysis This is a pragmatic, multicentre, randomised controlled trial targeting Chinese patients with APAC duration longer than 72 hours. …”
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Cluster randomised controlled trial of screening for atrial fibrillation in people aged 70 years and over to reduce stroke: protocol for the pilot study for the SAFER trial by Martin R Cowie, Stephen Morris, Gregory Lip, Richard J McManus, Stephen Sutton, Jonathan Mant, Simon J Griffin, Sarah Hoare, Jenni Burt, Rachel Johnson, Mark Lown, Alison Powell, Natalie Armstrong, FD Richard Hobbs, Trudie Lobban, Rakesh Narendra Modi, Ben Freedman, David A Fitzmaurice, Stephen Kaptoge, Jenny Lund, Duncan Edwards, Kate Williams, H Thom, Francesco Fusco, Michael J Sweeting, Andrew Dymond, The SAFER Authorship Group

“…The aim of the pilot study is to assess feasibility of the main trial and inform implementation of screening and trial procedures.Methods and analysis SAFER is planned to be a pragmatic randomised controlled trial (RCT) of over 100 000 participants aged 70 years and over, not on long-term anticoagulation therapy at baseline, with an average follow-up of 5 years. …”
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Theory-informed refinement and tailored implementation of a quality improvement program in maternity care to reduce unwarranted clinical variation across a health service network by Kym Warhurst, Zephanie Tyack, Michael Beckmann, Bridget Abell

“…Conclusions Implementation science theory and quality improvement processes can be integrated pragmatically to engage clinicians to address unwarranted clinical variation, with the objective of creating meaningful behaviour change, and system-level improvements for better healthcare outcomes. …”
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Factors Associated with Serious Injuries among Adolescents in Ghana: Findings from 2012 Global School Health Survey by Martin Ackah, Mohammed Gazali Salifu, Hosea Boakye

“…This study also revealed that factors such as educational level, suicidal ideation, suicidal attempt, at least one close friend, school truancy, smoking marijuana, and amphetamine use are associated with SI among the adolescents. Therefore, pragmatic interventional programs should be targeted at these factors to curb the rate of SI among junior and senior school students.…”
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Implementing injury prevention training in youth handball (I-PROTECT) in Sweden: study protocol for a cluster randomised trial by Per Nilsen, Alex Donaldson, Eva Ageberg, Sofia Bunke, Jennie Linnéll, Karin Moesch, Karolina Lucander, Axel Ström, Robert Wedberg, Per Ekberg

“…Within the I-PROTECT research project, the specific aim of this study is to investigate the implementation of the end-user-targeted I-PROTECT programme.Methods and analysis This pragmatic two-armed cluster randomised controlled trial is conducted collaboratively with the Swedish Handball Federation that has overall responsibility for handball in Sweden. …”
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A cycle of invisibilisation: a qualitative study of Brazilian health system factors shaping access to long COVID care by Emma-Louise Aveling, Margareth Crisóstomo Portela, Letícia Soares, Bárbara Caldas, Brenda Sabaine, Flora Cornish

“…Verbatim transcripts were analysed using a pragmatic thematic analysis.Results LC patients’ candidacy for care is invisibilised within SUS through multiple, interacting processes. …”
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TOOLS OF INTERCULTURAL COMMUNICATION IN INTERNATIONAL BUSINESS: A POSTCOLONIAL APPROACH by Eldar Veremchuk, Hennadii Vasylchuk

“…The methodology of the research relied on the following methods: firstly, the method of continuous sampling, which was employed to select language communicative contexts for analysis; secondly, the method of semantic and pragmatic analysis, which was used to identify the meaning of language units used in intercultural communication and their impact on the recipient; and thirdly, the method of interpretative analysis of text from the advertising discourse, which was used to find the hidden meanings and implications in marketing messages. …”
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BreathCarer: Informal carers of patients with chronic breathlessness: a mixed-methods systematic review of burden, needs, coping, and support interventions by Saskia Blütgen, Anne Pralong, Carolin Wilharm, Yvonne Eisenmann, Raymond Voltz, Steffen T. Simon

“…A narrative analysis of the quantitative results and a pragmatic meta-aggregation of the qualitative findings were performed, followed by a mixed-methods convergent segregated approach. …”
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The role of L.M. Karakhan in the Chinese policy of the Soviet Union (1923–1926) by I. N. Sotnikova

“…Under those circumstances, the country’s foreign ministry needed experienced, flexible, and pragmatic diplomats. In this regard, the activities of L.M. …”
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Enhancing maternity healthcare workers’ wellbeing using insider participatory action research by Claire M. Wood, Mary Chambers, Jayne E. Marshall

“…Methods Insider Participatory Action Research (IPAR) used positive psychology within a social constructionist, pragmatic approach. All clinical and non-clinical HCWs on a consultant-led labour ward in the East Midlands, England, UK were invited to identify current sources of workplace wellbeing on which to collectively construct future ways of working. …”
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Cadaveric simulation versus standard training for postgraduate trauma and orthopaedic surgical trainees: protocol for the CAD:TRAUMA study multicentre randomised controlled educati... by Damian Griffin, Hannah K James, Giles T R Pattison, Joanne D Fisher

“…These procedures have been selected as they are very common procedures which are routinely performed by junior surgeons-in-training. A pragmatic approach to sample size is taken in lieu of a formal power calculation as this is novel exploratory work with no a priori estimate of effect size to reference. …”
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Proximal Hamstring Tendinopathy: A Systematic Review of Interventions by Anthony Michael Nasser, Bill Vicenzino, Alison Grimaldi, Jay Anderson, Adam Ivan Semciw

“… # Conclusions There is insufficient evidence to recommend any one intervention over another. A pragmatic approach would be to initially trial approaches proven successful in other tendinopathies…”
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Association between polypharmacy and falls in older adults: a longitudinal study from England by Nafeesa N Dhalwani, Melanie J Davies, Kamlesh Khunti, Harini Sathanapally, Radia Fahami, Sam Seidu

“…Further exploration of the effects of these complex drug combinations in the real world with a detailed standardised assessment of polypharmacy is greatly required along with pragmatic studies in primary care, which will help inform whether the threshold for a detailed medication review should be lowered.…”
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Codeswitching – Ergebnisse einer Studie in der albanischen Sprachgruppe in Deutschland und der Schweiz by Naxhi Selimi, Basil Schader, Andrea Cantieni

“…The data indicate that our respondents used both the functional-pragmatic and lexical-compensatory and the demonstrative language-identity facets of code-switching. …”
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Turkish-Iranian Relations in the Middle East: in Search of the Regional Balance by I. A. Svistunova

“…The events of recent years have demonstrated that at the times when the Turkey and Iran sense common threats, they put their contradictions on the back burner. Pragmatism and rivalry in Turkish-Iranian relations are not alternatives but exist in parallel as a way of maintaining a regional balance of power between the two countries. …”
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KULTŪRINIO IR SIMBOLINIO KAPITALO GAMYBA: "DISNEY" FENOMENAS by Gintautas Mažeikis

“…The corporation uses pragmatism as a philosophical foundation.  The  only  truth  for  the  corporation  is production of pleasure and profit for all consumers. …”
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Conversational Therapy through Semi-Immersive Virtual Reality Environments for Language Recovery and Psychological Well-Being in Post Stroke Aphasia by A. Giachero, M. Calati, L. Pia, L. La Vista, M. Molo, C. Rugiero, C. Fornaro, P. Marangolo

“…The recent application of virtual reality (VR) to aphasia rehabilitation has already evidenced its usefulness in promoting a more pragmatically oriented treatment than conventional therapies (CT). …”
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Sequencing and Integration of Cervical Manual Therapy and Vestibulo-oculomotor Therapy for Concussion Symptoms: Retrospective Analysis by Christopher Kevin Wong, Lauren Ziaks, Samantha Vargas, Tessia DeMattos, Chelsea Brown

“…Musculoskeletal, vision, and vestibular system functions were assessed after pragmatic treatment including early cervical manual therapy and canalith repositioning treatment—when indicated—integrated with advanced vision and vestibular rehabilitation. …”
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