Tecovirimat in the management of poxviruses: a narrative review of available evidence by Olalekan John Okesanya, Jerico Bautista Ogaya, Ikponmwosa Jude Ogieuhi, Mohamed Mustaf Ahmed, Bonaventure Michael Ukoaka, Ojoisimi Franca Jamgbadi, Deborah Oluwaseun Shomuyiwa, Don Lucero-Prisno Eliseo, Blessing Olawunmi Amisu, Olakulehin Adebusuyi, William K. Chung, Emery Manirambona, Nimat Bola Idris, Janet Alexis A. De los Santos

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TESTING SHEEP AND GOAT POX VIRUSES FOR THEIR REPRODUCTION IN PRIMARY AND SUBCULTURED CELLS by A. B. Sarbasov, B. L. Manin, R. V. Yashin, I. N. Shumilova, V. I. Diev

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In-silico formulation of a next-generation polyvalent vaccine against multiple strains of monkeypox virus and other related poxviruses. by Abu Tayab Moin, Nurul Amin Rani, Rajesh B Patil, Tanjin Barketullah Robin, Md Asad Ullah, Zahidur Rahim, Md Foyzur Rahman, Talha Zubair, Mohabbat Hossain, A K M Moniruzzaman Mollah, Nurul Absar, Mahboob Hossain, Mohammed Abul Manchur, Nazneen Naher Islam

“…Mpox (formerly known as monkeypox) virus and some related poxviruses including smallpox virus pose a significant threat to public health, and effective prevention and treatment strategies are needed. …”
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Geographic Distribution of Vaccinia Virus, Diagnosis and Demographic Aspects of Affected Populations, Minas Gerais, Brazil, 2000–2023 by Pedro H. B. e Silva, Maycon D. de Oliveira, Iara M. de Almeida, Iago J. S. Domingos, Ana G. Stoffella-Dutra, Galileu Barbosa Costa, Jaqueline S. de Oliveira, Felipe C. M. Iani, Márcio R. de Castro, Jonatas S. Abrahão, Erna G. Kroon, Giliane de S. Trindade

Subjects: “…poxvirus…”
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A phase 1b clinical trial to determine the safety, tolerability and immunogenicity of simian adenovirus and poxvirus vectored vaccines against Mycobacterium avium complex subspecies in patients with active Crohn’s diseaseResearch in context by Jeremy Sanderson, Jeremy Aboagye, Rebecca Makinson, Katerina Rapi, Samuel Provstgaard-Morys, Lisa Stockdale, Alison Lawrie, Isabelle Lanigan, Nishat Halim, Abdel Douiri, Emily Greenlay, Rayka Malek, Emma Gray, Lindsey West, Fatima El Oulidi, Paul Ian Cross, Michael Stallibrass, Sarah C. Gilbert, Adrian V.S. Hill, Katie J. Ewer

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Domestic Dogs Exposed to Orthopoxvirus in Urban Areas of Brazil by Débora de Meneses, Ana G. Stoffella-Dutra, Vicenzo S. Blaso, Iara M. de Almeida, Karolina L. Dias, Iago José da S. Domingos, Gabriela P. Ribeiro, Wendel Coura-Vital, Alexandre B. Reis, Thallyta M. Vieira, Giliane de S. Trindade

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Monkeypox and other orthopoxvirus zoonoses by K. N. Gruzdev

“…Scientists are alarmed by these facts as the camelpox virus genomeis 99% homologous to the genome of the small poxvirus. This requires strengthening the epizootological and epidemiological monitoring of orthopoxvirus zoonotic pathogens.…”
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Culex quinquefasciatus: status as a threat to island avifauna and options for genetic control by Tim Harvey-Samuel, Thomas Ant, Jolene Sutton, Chris N. Niebuhr, Samoa Asigau, Patricia Parker, Steven Sinkins, Luke Alphey

“…Three pathogens of concern are the avian malaria parasites, the avian poxviruses, and West Nile virus—each of which can be transmitted by Culex quinquefasciatus, a highly adaptive and invasive mosquito. …”
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Temporal and spatial characterization of keratinocytes supporting orf virus replication by Byung-Joon Seung, Sushil Khatiwada, Daniel L. Rock, Gustavo Delhon

“…Reflecting their tropism for keratinocytes, most poxviruses that infect vertebrates replicate to high titers and cause pathology in the skin. …”
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The dangerous biology of pathogenic germs by Berche, Patrick

“…Moreover, it is now possible to chemically synthesise any microorganism from in silico sequences, including the most dangerous viruses (poxviruses, Ebola, etc.), whose sequences are accessible. …”
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Candidate antirheumatic genotherapeutic plasmid constructions have low immunogenicity by T. S. Nepomnyashchikh, T. V. Tregubchak, S. N. Yakubitskiy, O. S. Taranov, R. A. Maksyutov, S. N. Shchelkunov

“…Viral genes coding for immunomodulatory factors could be used to create new gene therapy products to treat RA and other human disease. Poxviruses, as compared to other viral families, have an unprecedentedly rich set of such immunomodulatory genes. …”
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Vδ2 T-cells response in people with Mpox infection: a three-month longitudinal assessment by Eleonora Cimini, Eleonora Tartaglia, Francesco Messina, Andrea Coppola, Valentina Mazzotta, Massimo Tempestilli, Giulia Matusali, Stefania Notari, Annalisa Mondi, Gianluca Prota, Alessandra Oliva, Carla Fontana, Enrico Girardi, Fabrizio Maggi, Andrea Antinori

“…IFN-γ-producing γδ T-cells in the resistance to poxviruses may a key role in inducing a protective type 1 memory immunity. …”
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