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1521
Targeted co-delivery nanosystem based on methotrexate, curcumin, and PAMAM dendrimer for improvement of the therapeutic efficacy in cervical cancer
Published 2025-01-01“…Considering these findings, the co-delivery NC shows promise for additional in vitro investigations and possesses the capacity to function as an effective framework for the combined delivery of MTX and Cur in cervical cancer chemotherapy.…”
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1522
Phenolic compounds from Chaenomeles speciosa alleviate inflammation in lipopolysaccharide-treated RAW264.7 macrophages via the NF-κB and MAPK pathways
Published 2023-07-01“…Chaenomeles speciosa (Sweet) Nakai cultivated widely in temperate regions possesses anti-inflammatory properties, however, the underlying molecular mechanisms remain not fully understood. …”
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1523
Integrating Pull Request Comment Analysis and Developer Profiles for Expertise-Based Recommendations in Global Software Development
Published 2025-01-01“…The complexity of this problem arises from the required combination of the developer’s level of technical expertise, domain knowledge, and the extent to which they possess the collaborative skills necessary for a successful project. …”
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1524
Thermoset and thermoplastic polymer composite with date palm fiber and its behavior: A review
Published 2025-01-01“…Abstract Date palm fibers possess mechanical properties to synthetic fibers, making them a promising material for fabricating sustainable composites. …”
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1525
Optimization of WEDM process parameters for machining hybrid composites (LM6/B4C/Fly Ash)
Published 2025-01-01“…IntroductionWire-electric discharge machining (WEDM) possesses multiple benefits over traditional production approaches; it allows for the precise processing of complex and rigid particulate-reinforced composite materials. …”
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1526
Microstructural evolution and wear performance of Ti662 alloy reinforced with FeCoCrCuSi high entropy alloy using microwave sintering
Published 2025-01-01“…The annealed composite possesses exceptional microhardness of 796 HV, which is 3.2 and 1.6 times higher than the Ti662 alloy and Ti662/HEA composite. …”
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1527
Nanozyme based ultra-stretchable, low-hysteresis, and dual-mode antibacterial composite hydrogels for wound healing
Published 2025-04-01“…Using dynamic micelles as the energy dissipation mechanism, double bonds and intermolecular interactions as two crosslinking methods in HMAux make it possess good stretchability (3244 %–4524 %), toughness (593.8 kJ/m3 to 421.5 kJ/m3), and low hysteresis (0.13–0.15). …”
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1528
The opposite effect of convulsant drugs on neuronal and endothelial nitric oxide synthase – A possible explanation for the dual proconvulsive/anticonvulsive action of nitric oxide...
Published 2023-03-01“…These convulsant drugs caused an increase in nNO, but a decrease in eNO was proportional to the duration of treatment in both cases. Apparently, nNO possesses convulsant properties mediated by its effect on the glutamatergic and GABAergic systems, probably through GABAA receptors. …”
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1529
Polychlorinated Biphenyls Water Pollution along the River Nile, Egypt
Published 2015-01-01“…Our findings revealed that PCBs possess a serious risk to the Egyptian population that depends mainly on the River Nile as a source of water. …”
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1530
Formononetin Administration Ameliorates Dextran Sulfate Sodium-Induced Acute Colitis by Inhibiting NLRP3 Inflammasome Signaling Pathway
Published 2018-01-01“…Formononetin is a kind of isoflavone compound and has been reported to possess anti-inflammatory properties. In this present study, we aimed to explore the protective effects of formononetin on dextran sulfate sodium- (DSS-) induced acute colitis. …”
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1531
A Second-Iteration Square Koch Fractal Slot Antenna for UHF Downlink Telemetry Applications in CubeSat Small Satellites
Published 2020-01-01“…Conveniently, this 56.56 cm full-length antenna possesses a geometry that allows it to be incorporated into the standardized 10 cm × 10 cm faces of the CubeSats. …”
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1532
Phytomedicine Potential of <i>Oroxylum indicum</i> Root and Its Constituents: Targeting Alzheimer’s Disease
Published 2025-01-01“…These findings suggest that <i>O. indicum</i> root extract, particularly baicalein, possesses multifaceted neuroprotective properties, targeting various aspects of AD pathogenesis, including oxidative stress, cholinergic dysfunction, β-amyloid formation, aggregation, and apoptosis. …”
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1533
Progesterone induces meiosis through two obligate co-receptors with PLA2 activity
Published 2025-01-01“…We show using functional assays coupled to unbiased and targeted cell-based lipidomics that ABHD2 possesses a phospholipase A2 (PLA2) activity that requires mPRβ. …”
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1534
Traumatic Brain Injury Promotes Neurogenesis and Oligodendrogenesis in Subcortical Brain Regions of Mice
Published 2025-01-01“…These findings suggest that subcortical structures, particularly the striatum and optic tract, may possess a potential for self-repair through neuronal regeneration and axon remyelination.…”
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1535
A Two-Stage Method for Screening Pulse RFI in SAR Raw Data Alternating the Use of Time and Frequency Domains
Published 2025-01-01“…Compared with the traditional PRFI screening methods, the proposed approach boasts a remarkable ability to circumvent missed screening and false alarm when screening weak-energy PRFIs. It possesses exceptional sensitivity and accuracy, offering fresh perspectives and innovative solutions to the PRFI screening challenge. …”
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1536
Agent-based risk analysis model for road transportation of dangerous goods
Published 2025-03-01“…In this paper, a DGT risk assessment method has been proposed and modeled using a multi-agents system, where each agent possesses specific attributes, failure modes, and behavioral patterns. …”
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1537
Bifunctional Electromagnetic Manipulation of Surface Waves Using Metasurfaces Under One Circularly Polarized Incidence
Published 2025-01-01“…Constructed using carefully selected and arranged meta-atoms that possess both structural resonance and a geometric phase, this kind of meta-device can exhibit two distinct SPP manipulation functionalities in both co- and cross-polarized output channels under one CP incidence. …”
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1538
Morphometric Investigation of a Species Complex in <i>Mimosa</i> Section <i>Batocaulon</i> Series <i>Cordistipulae</i> (Leguminosae, Caesalpinioideae)
Published 2025-01-01“…Most species are endemic to Northeastern Brazil, and some possess characters deemed diagnostic which nonetheless overlap, making species identification difficult. …”
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1539
Essential oils modulate virulence phenotypes in a multidrug-resistant pyomelanogenic Pseudomonas aeruginosa clinical isolate
Published 2025-01-01“…Abstract Pyomelanogenic P. aeruginosa, frequently isolated from patients with urinary tract infections and cystic fibrosis, possesses the ability to withstand oxidative stress, contributing to virulence and resulting in persistent infections. …”
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1540
Metformin-induced mitophagy suppresses auditory hair cell apoptosis via AMPK pathway
Published 2025-02-01“…Additionally, it has been noted that metformin possesses the specific ability to induce mitophagy. …”
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