3D bioprinting lobule-like hepatorganoids with induced vascularization for orthotopic implantation by Jianing Yan, Zhichao Ye, Yiwei Lu, Yuyang Yuan, Xiaofeng Wang, Tingting Yan, Jun Yin, Yifan Wang

“…Loaded with a prolonged released system of vascular endothelial growth factor (VEGF) and infused with human umbilical vein endothelial cells (HUVECs), we developed a fabricating method of vascularized lobule-like hepatorganoids (VLH) which possessed promoted vascularization. We identified GAS6/AXL and LAMB3/ITGA3 signaling pathway up-regulated in VLH, which was conducive to vascularization and proliferation. …”
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MOLECULAR SCREENING OF POTATO VARIETIES BRED IN THE NORTHWESTERN ZONE OF THE RUSSIAN FEDERАTION by Т. A. Gavrilenko, N. S. Klimenko, O. Yu. Antonova, V. A. Lebedeva, Z. Z. Evdokimova, N. M. Gadjiyev, O. V. Apalikova, N. V. Alpatyeva, L. I. Kostina, N. M. Zoteyeva, F. T. Mamadbokirova, K. V. Egorova

“…Many potato varieties created in the Leningrad Scientific Research Institute of Agriculture “Belogorka” are multi-species hybrids possessing complex resistance to the most spread pathogens in combination with a high plasticity, which determined their zoning in many regions of the Russian Federation. …”
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Soil porosity as a key factor of soil aggregate stability: insights from restricted grazing by Yi Yang, Yi Yang, Yi Yang, Zhongju Meng, Zhongju Meng, Zhongju Meng, Haonian Li, Haonian Li, Haonian Li, Yue Gao, Yue Gao, Yue Gao, Tianyang Li, Tianyang Li, Tianyang Li, Lei Qin

“…The findings obtained from the computations using the boosted regression tree (BRT) demonstrated that, within the study period, soil porosity significantly affects soil aggregate stability compared to other factors. Moreover, it possessed an average explanatory power that surpassed 45%. …”
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The clinical impact of recent amphetamine exposure in aneurysmal subarachnoid hemorrhage patients by Jeffrey R. Vitt, Roger C. Cheng, Jason Chung, Travis Caton, Bo Zhou, Nerissa Ko, Karl Meisel, Edilberto Amorim

“…BackgroundAmphetamines possess sympathomimetic properties that can affect cerebral vasculature though conflicting reports exist about their effect on vasospasm risk and clinical outcomes in aneurysmal subarachnoid hemorrhage. …”
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Adjunctive diagnostic tool for histopathological classification of congenital mesoblastic nephroma based in molecular genetic findings by Hiroshi Hamada, Kenichi Kohashi, Takeshi Iwasaki, Mikiko Hashisako, Yuko Hino, Masahiro Fukuhara, Amane Kamouchi, Naonori Kawakubo, Tatsuro Tajiri, Yoshinao Oda

“…Thus, MEK1/2 inhibitors possess the potential to be used as a targeted therapy for CMN with EGFR-ITDs.…”
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MicroRNA-21 as a Regulator of Cancer Stem Cell Properties in Oral Cancer by Milica Jaksic Karisik, Milos Lazarevic, Dijana Mitic, Maja Milosevic Markovic, Nicole Riberti, Drago Jelovac, Jelena Milasin

“…CD44+ and CD44− populations were sorted via magnetic separation. miRNA-21 inhibition was performed in CD44+ cells via transfection. CD44+ cells possessed a significantly higher migration and invasion potential compared to CD44− cells, higher levels of miRNA-21 (<i>p</i> = 0.004) and β-catenin (<i>p</i> = 0.005), and lower levels of BAX (<i>p</i> = 0.015). miRNA-21 inhibition in CD44+ cells reduced migration, invasion, and colony formation while increasing apoptosis. …”
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Genome-wide identification and functional roles relating to anthocyanin biosynthesis analysis in maize by Xiaofang Wang, Huangai Li, Shuai Wang, Meiqi Ruan, Yiping Li, Lei Zhu, Zhenying Dong, Yan Long

“…Maize silk, serving as an important reproductive organ and displaying a diverse range of colors, plays an indispensable role in biotic resistance through its possession of anthocyanin. However, the copy numbers, characteristics, and expression patterns of genes involved in maize anthocyanin biosynthesis are not fully understood. …”
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Analysis of MRI imaging characteristics in 10 cases of adult granulosa cell tumor with normal estrogen levels by Wei Weng, Yaomeng Chen, Ze Liu, Weiqian Chen, Jiejie Hu, Huihui Chen, Xindian Pan, Hai Wu, Xinle Chi

“…Conclusion The MRI characteristics of primary and metastatic lesions in AGCT-NEL possess specific features, such as signs of hemorrhage, absence of wall nodules in the cystic portions of the tumors, and distinctive honeycomb and Swiss cheese signs, with metastatic lesions being cystic. …”
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Effect of a bimetal Mn/Zn catalyst supported on activated carbon for selective oxidation of ethyl lactate to ethyl pyruvate by G. Madhanagopal, K. Premalatha, P.N. Poovizhi, V. Sumithra, S. Mahalingam, L. Guganathan, S. Sivakumar, A. Subramani, P. Tamizhdurai

“…The AC/Mn/Zn catalyst possessed a unique combination of Brønsted and Lewis acid sites, making it ideal for the target reaction. …”
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Design of multifunctional interfaces on ceramic solid electrolytes for high-performance lithium-air batteries by Yunxin Shi, Ziyang Guo, Changhong Wang, Mingze Gao, Xiaoting Lin, Hui Duan, Yonggang Wang, Xueliang Sun

“…As a result, the DSCCE-based Li–air batteries possess high capacity/low voltage polarization (11,836 mA h g−1/1.45 V under 500 mA g−1), good rate performance (capacity ratio under 1000 mA g−1/250 mA g−1 is 68.2%) and long-term stable cell operation (∼300 cycles at 750 mA g−1 with 750 mAh g−1) in ambient air.…”
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A national cross-sectional study on latent profile analysis of occupational fatigue among Chinese nurses in the early post-COVID-19 era by Qiuyang He, Qiuyang He, Jianhua Ren, Jianhua Ren, Guoyu Wang, Guoyu Wang, Yonghong Wang, Yonghong Wang

“…Significant predictors for membership in these fatigue profiles included marital status, possession of a master’s degree or higher, working over five night shifts per month, experiencing COVID-19 symptoms, and exhibiting higher scores in extrinsic effort and overcommitment.ConclusionChinese nurses exhibit a relatively high level of occupational fatigue in the early post-COVID-19 era, likely influenced by various socio-demographic and work-related factors. …”
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Inflammatory biomarkers of neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios in 563 severe OSA patients before and after surgery by Chung-Wei Lin, Pei-Wen Lin, Li-Wen Chiu, Han-Tan Chai, Chun-Tuan Chang, Michael Friedman, Anna M. Salapatas, Sara Rahavi-Ezabadi, Hsin-Ching Lin

“…Conclusion NLR and PLR did significantly drop in severe OSA patients following OSA surgery, and this could be related to the alterations of sleep indices. The findings could possess clinical importance for severe OSA patients after OSA surgeries in reducing possible OSA-associated cardiovascular comorbidities.…”
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Natural pigments: innovative extraction technologies and their potential application in health and food industries by Ayu Masyita, Gemala Hardinasinta, Ayun Dwi Astuti, Firdayani Firdayani, Dian Mayasari, Aki Hori, Ira Nur Ainun Nisha, Firzan Nainu, Takayuki Kuraishi

“…Beyond their color properties, these pigments possess several biological activities, including antioxidant, anti-inflammatory, anticancer, antibacterial, and neuroprotective effects, as well as benefits for eye health. …”
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Development of an Adaptable Qualification Test Set for Personnel Involved in Visual Inspection Procedures of Parenteral Drug Products Manufactured Under Good Manufacturing Practice... by Tessa van den Born-Bondt, Harmen P. S. Huizinga, Koen R. Kappert, Hans H. Westra, Jacoba van Zanten, Herman J. Woerdenbag, Jacoba M. Maurer, Bahez Gareb

“…However, both strategies inherently possess disadvantages and limitations. The objective of this study was to develop a manufacturing protocol for an optimal and adaptable QTS for training and qualification procedures. …”
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Saussurea costus alleviates ulcerative colitis by regulating the gut microbiota and improving intestinal barrier integrity by Wen-lin Pang, Wen-lin Pang, Tian-gang Li, Tian-gang Li, Yin-ying Wang, Yin-ying Wang, Li-yun Song, Li-yun Song, Li Li, Li Li, Xiao-ya Li, Xiao-ya Li, Yong Qiu, Yong Qiu, Zhong-shan Yang, Zhong-shan Yang

“…Recent pharmacological research has shown that traditional Chinese medicine saussurea costus (SC) possesses beneficial antibacterial and anti-inflammatory properties. …”
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Facile Synthesis of Novel Conducting Copolymers Based on N-Furfuryl Pyrrole and 3,4-Ethylenedioxythiophene with Enhanced Optoelectrochemical Performances Towards Electrochromic App... by Huixian Li, Xiaomeng Sun, Datai Liu, Xinchang Liu, Xianchao Du, Shuai Li, Xiaojing Xing, Xinfeng Cheng, Dongqin Bi, Dongfang Qiu

“…The results demonstrate that the prepared P(FuPy-<i>co</i>-EDOT) copolymers with a higher proportion of EDOT units (FuPy/EDOT: 2/8~1/9) possess good redox activity, tunable optical absorption performances, and low band gaps (1.75~1.86 eV). …”
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Transcriptomic and functional characterization of megakaryocytic-derived platelet-like particles: impaired aggregation and prominent anti-tumor effects by Kaitlin Garofano, Vera Mariani, Kameron Rashid, Sumanun Suwunnakorn, Alfateh Sidahmed, Anelia Horvath, Sanjay B. Maggirwar, Travis J. O’Brien, Minoli A. Perera, Michael Whalen, Norman H. Lee

“…In summary, PLPs lack many transcriptomic, molecular and functional features of platelets and possess novel anti-tumorigenic properties. These findings indicate that PLPs may have a potential therapeutic role in targeting and disrupting the oncogenic signaling between platelets and cancer cells, offering a new avenue for anti-cancer strategies.…”
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Genome-wide identification of novel flagellar motility genes in Pseudomonas syringae pv. tomato DC3000 by Zichu Yang, Tyler Helmann, Maël Baudin, Maël Baudin, Maël Baudin, Karl J. Schreiber, Karl J. Schreiber, Zhongmeng Bao, Paul Stodghill, Paul Stodghill, Adam Deutschbauer, Adam Deutschbauer, Jennifer D. Lewis, Jennifer D. Lewis, Bryan Swingle, Bryan Swingle

“…Pseudomonas syringae pv. tomato DC3000 (Pst DC3000) is a plant pathogenic bacterium that possesses complicated motility regulation pathways including a typical chemotaxis system. …”
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Potency of Bone Marrow-Derived Mesenchymal Stem Cells and Indomethacin in Complete Freund’s Adjuvant-Induced Arthritic Rats: Roles of TNF-α, IL-10, iNOS, MMP-9, and TGF-β1 by Eman A. Ahmed, Osama M. Ahmed, Hanaa I. Fahim, Tarek M. Ali, Basem H. Elesawy, Mohamed B. Ashour

“…Indomethacin (IMC) could be suggested as an analgesic, anti-inflammatory, and antirheumatic potential agent against the course of RA since it possesses significant palliative effects and antipyretic properties. …”
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Impact of Wheat Harvest on Levels and Sources of PM2.5-associated PAHs in an Urban Area Located at the Center of Beijing-Tianjin-Hebei Region by Zhiyong Li, Zhenxin Li, Ziyuan Yue, Dingyuan Yang, Yutong Wang, Lan Chen, Songtao Guo, Jinsong Yao, Lei Wang, Xiao Lou, Xiaolin Xu, Jinye Wei, Baole Deng, Hong Wu

“…The reverse trend was found for PAH mass contents (in µg g–1), AWH possessed much higher value of 139 than 27.8 of DWH, while no significant fluctuations occurred for PAH concentrations due to the varied PM2.5 levels. …”
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