Fc-binding nanodisc restores antiviral efficacy of antibodies with reduced neutralizing effects against evolving SARS-CoV-2 variants by Jaehyeon Hwang, Soyun Choi, Beom Kyu Kim, Sumin Son, Jeong Hyeon Yoon, Kyung Won Kim, Wonbeom Park, Hyunjoo Choo, Suhyun Kim, Soomin Kim, Seokhyeon Yu, Sangwon Jung, Sang Taek Jung, Min-Suk Song, Sang Jick Kim, Dae-Hyuk Kweon

“…Furthermore, the Fc-binding nanodisc significantly boosted the antiviral efficacy of the soluble angiotensin-converting enzyme 2 (sACE2) Fc fusion protein, which possesses broad but modest antiviral activity. In ACE2 transgenic mice, the Fc-binding nanodisc protected better than sACE2-Fc alone with two more log reduction in lung viral titer. …”
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Investigating the inflammatory effect of microplastics in cigarette butts on peripheral blood mononuclear cells by Monire Soltani, Abbas Shahsavani, Philip K. Hopke, Nadali Alavi Bakhtiarvand, Mehrnoosh Abtahi, Masoumeh Rahmatinia, Majid Kermani

“…These microplastics are readily dispersed and can be found abundantly in water, soil, and air. These fibers possess high absorption capabilities, allowing them to collect and retain pollutants such as toxic elements. …”
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A novel roseosiphovirus infecting dinoroseobacter shibae DFL12T represents a new genus by Nana Wei, Longfei Lu, Yingying Li, Bo Ding, Lanlan Cai, Yunlan Yang

“…The phage has a narrow host range and demonstrates a long infection cycle with a latent period of 3.5 h and a burst size of 22 plaque-forming units (PFU cell− 1). R26L possesses a circular, double-stranded DNA genome of 79,534 bp with a G + C content of 62.6%, encoding a total of 116 open reading frames. …”
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A Nitrogen-Rich Covalent Triazine Framework as a Photocatalyst for Hydrogen Production by Ruizhi Gong, Liuliu Yang, Shuo Qiu, Wan-Ting Chen, Qing Wang, Jiazhuo Xie, Geoffrey I. N. Waterhouse, Jing Xu

“…XRD, SEM, and TEM characterization studies revealed CTF-CN to be amorphous and composed of ultrathin 2D sheets. CTF-CN possessed strong absorption at visible wavelengths, with UV-vis measurements suggesting a band gap energy in the range 2.7-2.9 eV. …”
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Development of sustained-release extemporaneous moxifloxacin loaded commercial soft hydrogel contact lenses by Duy Toan Pham, Pratthana Chomchalao, Kunasin Bunneramit, Phurichaya Kladcharoen, Rossukon Khotcharrat, Waree Tiyaboonchai

“…Amongst them, three contact lenses (Acuvue, Biomedics, and Maxim) showed high drug loading of ∼2 mg and adequate controllable drug release for 24 h with Maxim possessing the highest release rate, and maintained the effective drug therapeutic level for at least 12 h. …”
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Biological activity research of male papaya flowers Carica papaya L. on some common cancer cell lines by Ngô Thị Phương Dung, Nguyễn Hoàng Dũng

“…., is widely cultivated in Vietnam, and its flowers possess various pharmacological properties. This study focuses on the biological activities, including antioxidant and anticancer effects, of different fractions extracted from male papaya flowers. …”
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Effect of 2,4-Thiazolidinedione on Limousin Cattle Growth and on Muscle and Adipose Tissue Metabolism by M. Arévalo-Turrubiarte, L. González-Dávalos, A. Yabuta, J. D. Garza, J. L. Dávalos, O. Mora, A. Shimada

“…The main adipogenic transcription factor PPARγ possesses high affinity to 2,4-TZD, a member of the Thiazolidinedione family of insulin-sensitizing compounds used as adipogenic agents. …”
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Characterization and genomic insights into bacteriophages Kpph1 and Kpph9 against hypervirulent carbapenem-resistant Klebsiella pneumoniae by Ye Huang, Yuan Huang, Zhiping Wu, Ziyue Fan, Fanglin Zheng, Yang Liu, Xinping Xu

“…In this study, two isolated bacteriophages, Kpph1 and Kpph9, were characterized for their specificity against the Hv-CRKp K. pneumoniae NUHL30457 strain that possesses a K2 capsule serotype. Both phages exhibit remarkable environmental tolerance, displaying stability over a range of pH values (4–11) and temperatures (up to 50°C). …”
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In silico comparative genomic analysis unravels a new candidate protein arsenal specifically associated with Fusarium oxysporum f. sp. albedinis pathogenesis by Hafida Ayada, Boutayna Dhioui, Hamid Mazouz, Abdelhay El harrak, Fatima Jaiti, Bouchra Ouhmidou, Mohammed Diouri, Mohieddine Moumni

“…Foa secretome analysis revealed that both Foa strains possess an expanded number of secreted effectors (3003 in Foa 133 and 2418 in Foa 9). …”
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Induced mesenchymal stem cells generated from periodontal ligament fibroblast for regenerative therapy by Hemanathan Vembuli, Sheeja Rajasingh, Patrick Nabholz, Jefferson Guenther, Brian R. Morrow, Margaret M. Taylor, Marziyeh Aghazadeh, Vinoth Sigamani, Johnson Rajasingh, Johnson Rajasingh, Johnson Rajasingh

“…The resulting iMSCs were homogeneous, highly proliferative, and possessed anti-inflammatory properties, suggesting their potential as a superior alternative to traditional MSCs for regenerative therapy. …”
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Experimental study of the strengthening efficiency of engineering waste sludge using electro-osmosis by Yanli TAO, Zeyi YU, Jianfeng ZHU, Xiaonan GONG, Jian ZHOU, Kaiqiang LI

“…Total and effective electro-osmotic efficiency decreases with the increasing potentials. Electrode materials possess little influence on the electro-osmotic efficiency, but have indirect impact through effective potential due to the anode material loss. …”
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Perspectives on Structural, Physiological, Cellular, and Molecular Responses to Desiccation in Resurrection Plants by Yathisha Neeragunda Shivaraj, Plancot Barbara, Bruno Gugi, Maïté Vicré-Gibouin, Azeddine Driouich, Sharatchandra Ramasandra Govind, Akash Devaraja, Yogendra Kambalagere

“…Resurrection plants possess a unique ability to counteract desiccation stress. …”
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A Truncated Multi-Thiol Aptamer-Based SARS-CoV-2 Electrochemical Biosensor: Towards Variant-Specific Point-of-Care Detection with Optimized Fabrication by Sergio Roberto Molina Ramirez, Nafiseh Samiseresht, Mateo Alejandro Martínez-Roque, Ferdinando Catania, Kevin Graef, Martin Rabe, Andreas Offenhäusser, Dirk Mayer, Gabriela Figueroa-Miranda

“…The analyte–receptor binding was further confirmed spectroscopically at the level of individual molecules by AFM-IR. The aptasensor possesses a low limit of detection (8.0 fg/mL), the highest sensitivity reported for S protein (209.5 signal per concentration decade), and a wide dynamic detection range (8.0 fg/mL–38 ng/mL) in nasopharyngeal samples, covering the clinically relevant range. …”
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Level-8 Ph.D. Programs In Medical Sciences: High Time For The Higher Education Commission (HEC) Of Pakistan To Establish A Medical Wing by Wafa Omer

“…PMDC requires that the supervisor of a PhD in medical sciences should possess an MBBS degree along with a PhD in the respective subject. …”
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A comparative study of menstrual poverty among urban and rural female learners in government schools of Zambia by Bwalya Bupe Bwalya, Ancietos Mwansa, Patrick Amanzi, Christabel Ngongola, Charity Meki-Kombe

“…Results The findings revealed that urban female learners possessed a more comprehensive understanding of menstruation than their rural peers, with a significantly higher proportion accurately defining the process (74% vs. 50%). …”
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Integration of Gastric Cancer RNA‐Seq Datasets Along With PPI Network Suggests That Nonhub Nodes Have the Potential to Become Biomarkers by Akram Siavoshi, Mehran Piran, Ali Sharifi‐Zarchi, Fatemeh Ataellahi

“…Considering the overall survival (OS) analysis and the evaluation of expression levels alongside statistical parameters of the PPIN cluster nodes, it is plausible to suggest that THY1, CDH17, TGIF1, and AEBP1, categorized as nonhub nodes, along with ITGA5, COL1A1, FN1, and MMP2, identified as hub nodes, possess characteristics that render them applicable as biomarkers for the GC. …”
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The use of molecular-genetic and phytopathological methods to identify genes for effective leaf rust resistance in Aegilops accessions by L. G. Tyryshkin, M. A. Kolesova

“…All accessions of Ae. tauschii, two of Ae. umbellulata, and three of Ae. biuncialis, possessing effective resistance genes according to the molecular testing, were susceptible to the pathogen population. …”
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Synergetic effects of nano-boehmite and Y nano-zeolite on catalytic cracking of residue oil by Ehsan Amini, Kamran Ahmadi, Alimorad Rashidi, Amir Ali Youzbashi, Mehran Rezaei, Sakineh Mesgar

“…On the other hand, in equal zeolite content, the alumina active matrix-based catalyst possessed higher acidity (NC30B20, 3.44 mmol NH3/g catalyst) than the silica inactive matrix-based catalyst (NC30B0, 2.31 mmol NH3/g catalyst). …”
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Identifying sources of resistance to late blight and black scurf, and other economically useful traits among interspecific potato hybrids by Z. Z. Evdokimova, M. V. Kalashnik

“…In the preliminary test nursery, from 4.0 to 62.0% of the tested accessions demonstrated high plant top resistance to late blight, and from 21.6 to 58.0% possessed tuber resistance. The analysis of resistance to black scurf showed that the average score for several years in the preliminary test nursery ranged from 6.3 to 7.6 points (the scale from 9 down to 1), while the percentage of highly resistant accessions was in the range of 25.9–70.7%. …”
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Identification and prioritization of novel therapeutic candidates against glutamate racemase from Klebsiella pneumoniae. by Ankit Kumar, Farah Anjum, Md Imtaiyaz Hassan, Anas Shamsi, Rashmi Prabha Singh

“…<h4>Background</h4>Klebsiella pneumoniae, a gram-negative bacterium in the Enterobacteriaceae family, is non-motile, encapsulated, and a major cause of nosocomial infections, particularly in intensive care units. The bacterium possesses a thick polysaccharide capsule and fimbriae, which contribute to its virulence, resistance to phagocytosis, and attachment to host cells. …”
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