3D bioprinting lobule-like hepatorganoids with induced vascularization for orthotopic implantation by Jianing Yan, Zhichao Ye, Yiwei Lu, Yuyang Yuan, Xiaofeng Wang, Tingting Yan, Jun Yin, Yifan Wang

“…Loaded with a prolonged released system of vascular endothelial growth factor (VEGF) and infused with human umbilical vein endothelial cells (HUVECs), we developed a fabricating method of vascularized lobule-like hepatorganoids (VLH) which possessed promoted vascularization. We identified GAS6/AXL and LAMB3/ITGA3 signaling pathway up-regulated in VLH, which was conducive to vascularization and proliferation. …”
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MOLECULAR SCREENING OF POTATO VARIETIES BRED IN THE NORTHWESTERN ZONE OF THE RUSSIAN FEDERАTION by Т. A. Gavrilenko, N. S. Klimenko, O. Yu. Antonova, V. A. Lebedeva, Z. Z. Evdokimova, N. M. Gadjiyev, O. V. Apalikova, N. V. Alpatyeva, L. I. Kostina, N. M. Zoteyeva, F. T. Mamadbokirova, K. V. Egorova

“…Many potato varieties created in the Leningrad Scientific Research Institute of Agriculture “Belogorka” are multi-species hybrids possessing complex resistance to the most spread pathogens in combination with a high plasticity, which determined their zoning in many regions of the Russian Federation. …”
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Soil porosity as a key factor of soil aggregate stability: insights from restricted grazing by Yi Yang, Yi Yang, Yi Yang, Zhongju Meng, Zhongju Meng, Zhongju Meng, Haonian Li, Haonian Li, Haonian Li, Yue Gao, Yue Gao, Yue Gao, Tianyang Li, Tianyang Li, Tianyang Li, Lei Qin

“…The findings obtained from the computations using the boosted regression tree (BRT) demonstrated that, within the study period, soil porosity significantly affects soil aggregate stability compared to other factors. Moreover, it possessed an average explanatory power that surpassed 45%. …”
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Adjunctive diagnostic tool for histopathological classification of congenital mesoblastic nephroma based in molecular genetic findings by Hiroshi Hamada, Kenichi Kohashi, Takeshi Iwasaki, Mikiko Hashisako, Yuko Hino, Masahiro Fukuhara, Amane Kamouchi, Naonori Kawakubo, Tatsuro Tajiri, Yoshinao Oda

“…Thus, MEK1/2 inhibitors possess the potential to be used as a targeted therapy for CMN with EGFR-ITDs.…”
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MicroRNA-21 as a Regulator of Cancer Stem Cell Properties in Oral Cancer by Milica Jaksic Karisik, Milos Lazarevic, Dijana Mitic, Maja Milosevic Markovic, Nicole Riberti, Drago Jelovac, Jelena Milasin

“…CD44+ and CD44− populations were sorted via magnetic separation. miRNA-21 inhibition was performed in CD44+ cells via transfection. CD44+ cells possessed a significantly higher migration and invasion potential compared to CD44− cells, higher levels of miRNA-21 (<i>p</i> = 0.004) and β-catenin (<i>p</i> = 0.005), and lower levels of BAX (<i>p</i> = 0.015). miRNA-21 inhibition in CD44+ cells reduced migration, invasion, and colony formation while increasing apoptosis. …”
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Genome-wide identification and functional roles relating to anthocyanin biosynthesis analysis in maize by Xiaofang Wang, Huangai Li, Shuai Wang, Meiqi Ruan, Yiping Li, Lei Zhu, Zhenying Dong, Yan Long

“…Maize silk, serving as an important reproductive organ and displaying a diverse range of colors, plays an indispensable role in biotic resistance through its possession of anthocyanin. However, the copy numbers, characteristics, and expression patterns of genes involved in maize anthocyanin biosynthesis are not fully understood. …”
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Effect of a bimetal Mn/Zn catalyst supported on activated carbon for selective oxidation of ethyl lactate to ethyl pyruvate by G. Madhanagopal, K. Premalatha, P.N. Poovizhi, V. Sumithra, S. Mahalingam, L. Guganathan, S. Sivakumar, A. Subramani, P. Tamizhdurai

“…The AC/Mn/Zn catalyst possessed a unique combination of Brønsted and Lewis acid sites, making it ideal for the target reaction. …”
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Inflammatory biomarkers of neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios in 563 severe OSA patients before and after surgery by Chung-Wei Lin, Pei-Wen Lin, Li-Wen Chiu, Han-Tan Chai, Chun-Tuan Chang, Michael Friedman, Anna M. Salapatas, Sara Rahavi-Ezabadi, Hsin-Ching Lin

“…Conclusion NLR and PLR did significantly drop in severe OSA patients following OSA surgery, and this could be related to the alterations of sleep indices. The findings could possess clinical importance for severe OSA patients after OSA surgeries in reducing possible OSA-associated cardiovascular comorbidities.…”
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Development of an Adaptable Qualification Test Set for Personnel Involved in Visual Inspection Procedures of Parenteral Drug Products Manufactured Under Good Manufacturing Practice... by Tessa van den Born-Bondt, Harmen P. S. Huizinga, Koen R. Kappert, Hans H. Westra, Jacoba van Zanten, Herman J. Woerdenbag, Jacoba M. Maurer, Bahez Gareb

“…However, both strategies inherently possess disadvantages and limitations. The objective of this study was to develop a manufacturing protocol for an optimal and adaptable QTS for training and qualification procedures. …”
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Saussurea costus alleviates ulcerative colitis by regulating the gut microbiota and improving intestinal barrier integrity by Wen-lin Pang, Wen-lin Pang, Tian-gang Li, Tian-gang Li, Yin-ying Wang, Yin-ying Wang, Li-yun Song, Li-yun Song, Li Li, Li Li, Xiao-ya Li, Xiao-ya Li, Yong Qiu, Yong Qiu, Zhong-shan Yang, Zhong-shan Yang

“…Recent pharmacological research has shown that traditional Chinese medicine saussurea costus (SC) possesses beneficial antibacterial and anti-inflammatory properties. …”
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Genome-wide identification of novel flagellar motility genes in Pseudomonas syringae pv. tomato DC3000 by Zichu Yang, Tyler Helmann, Maël Baudin, Maël Baudin, Maël Baudin, Karl J. Schreiber, Karl J. Schreiber, Zhongmeng Bao, Paul Stodghill, Paul Stodghill, Adam Deutschbauer, Adam Deutschbauer, Jennifer D. Lewis, Jennifer D. Lewis, Bryan Swingle, Bryan Swingle

“…Pseudomonas syringae pv. tomato DC3000 (Pst DC3000) is a plant pathogenic bacterium that possesses complicated motility regulation pathways including a typical chemotaxis system. …”
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Potency of Bone Marrow-Derived Mesenchymal Stem Cells and Indomethacin in Complete Freund’s Adjuvant-Induced Arthritic Rats: Roles of TNF-α, IL-10, iNOS, MMP-9, and TGF-β1 by Eman A. Ahmed, Osama M. Ahmed, Hanaa I. Fahim, Tarek M. Ali, Basem H. Elesawy, Mohamed B. Ashour

“…Indomethacin (IMC) could be suggested as an analgesic, anti-inflammatory, and antirheumatic potential agent against the course of RA since it possesses significant palliative effects and antipyretic properties. …”
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Impact of Wheat Harvest on Levels and Sources of PM2.5-associated PAHs in an Urban Area Located at the Center of Beijing-Tianjin-Hebei Region by Zhiyong Li, Zhenxin Li, Ziyuan Yue, Dingyuan Yang, Yutong Wang, Lan Chen, Songtao Guo, Jinsong Yao, Lei Wang, Xiao Lou, Xiaolin Xu, Jinye Wei, Baole Deng, Hong Wu

“…The reverse trend was found for PAH mass contents (in µg g–1), AWH possessed much higher value of 139 than 27.8 of DWH, while no significant fluctuations occurred for PAH concentrations due to the varied PM2.5 levels. …”
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Lines resistant to downy mildew in the sunflower genetic collection at VIR by V. A. Gavrilova, T. G. Stupnikova, L. G. Makarova, N. V. Alpatieva, Yu. I. Karabitsina, E. B. Kuznetsova, I. A. Anisimova

“…Lines ТА 716-18, VIR 768 and VIR 800 appeared highly resistant to the pathogen and probably possess new resistance genes/alleles introgressed from wild species.…”
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Bioinorganic Synthesis of Polyrhodanine Stabilized Fe3O4/Graphene Oxide in Microbial Supernatant Media for Anticancer and Antibacterial Applications by Seyyed Mojtaba Mousavi, Seyyed Alireza Hashemi, Ahmad Gholami, Navid Omidifar, Maryam Zarei, Sonia Bahrani, Khadije Yousefi, Wei-Hung Chiang, Aziz Babapoor

“…Our results showed that Go/Fe has the highest average inhibitory effect against Escherichia coli and Pseudomonas aeruginosa, and this compound possesses the least antimicrobial effect on Staphylococcus aureus. …”
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The proneural transcription factor Atoh1 promotes odontogenic differentiation in human dental pulp stem cells (DPSCs) by Camila Sabatini, Huey-Jiun Lin, Galib Ovik, Richard Hall, Techung Lee

“…Conclusions Atoh1, despite being a proneural transcription factor in development, possesses a novel odontogenic function upon ectopic expression in DPSCs. …”
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Evaluation of the Knowledge, Attitudes and Practice of Veterinary Professionals and Senior Animal Health Students in Central Gondar Zone, Gondar, Ethiopia: Antimicrobial Use and Re... by Abibo Wondie Mekonen, Yesuneh Tefera Mekasha, Melaku Getahun Feleke, Atsede Getaneh, Meron Dereje, Misganew Bafe, Sete Nigussie, Achenef Melaku Beyene

“…In order to combat this issue and promote responsible antimicrobial use (AMU), it is imperative for veterinary professionals and graduating students to possess extensive knowledge, maintain positive attitudes, and adhere to good practices regarding AMU and AMR. …”
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Antioxidant and Anti-Inflammatory Potential of Cymbopogon nardus Ethanol Extract on 3T3-L1 Cells by Rohmawaty E, Wiraswati HL, Zahra TA, Amalina SN, Ramadhanti J, Rosdianto AM, Laelalugina A, Nasution GTD, Kamisah Y

“…Recent studies have suggested that its bioactive constituents possess antioxidant and anti-inflammatory properties. …”
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THE USE OF ZIRCONIUM CEMENTS IN MEDICINE: PHYSICO-CHEMICAL PROPERTIES AND CLINICAL BENEFITS by Giuroiu Cristian Levente, Clara Haddad, Cristina Albert, Doina Spaiuc, Rusnac Roman, Cezarina Dragomirescu, Alexandru Patrascu, Alina Stefanache

“…Furthermore, these cements show strong durability against chemical breakdown and possess great aesthetic qualities that closely resemble natural tooth enamel. …”
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OMEGA-3 Fatty Acids Retention, Oxidative Quality, and Sensoric Acceptability of Spray-Dried Flaxseed Oil by Muhammad Zia Shahid, Muhammad Imran, Muhammad Kamran Khan, Muhammad Haseeb Ahmad, Muhammad Nadeem, Niaz Muhammad, Adeela Yasmin

“…In the case of color and overall acceptability, the lowest evaluation scores were awarded to FSO samples in comparison to SDFSO samples. Overall, SDFSO possessed improved oxidative quality and can be recommended as a fortifying agent in various functional food products.…”
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