Initial Assessment of β-Adrenoceptor-Activated Brown Adipose Tissue in Streptozotocin-Induced Type 1 Diabetes Rodent Model Using [F]Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography by Aparna Baranwal, M. Reza Mirbolooki, Jogeshwar Mukherjee

“…Metabolic activity of brown adipose tissue (BAT) is activated by β 3 -adrenoceptor agonists and norepinephrine transporter (NET) blockers and is measurable using [ 18 F]fluorodeoxyglucose ([ 18 F]FDG) positron emission tomography/computed tomography (PET/CT) in rats. …”
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Monitoring the Induction of Heat Shock Factor 1/Heat Shock Protein 70 Expression following 17-Allylamino-Demethoxygeldanamycin Treatment by Positron Emission Tomography and Optical Reporter Gene Imaging by Mikhail Doubrovin, Jian T. Che, Inna Serganova, Ekaterina Moroz, David B. Solit, Lyudmila Ageyeva, Tatiana Kochetkova, Nagavarakishore Pillarsetti, Ronald Finn, Neal Rosen, Ronald G. Blasberg

“…We demonstrate that an [ 124 I]iodide-pQHNIG70 positron emission tomography (PET) reporter system that includes an inducible HSP70 promoter can be used to image and monitor the activation of the HSF1/HSP70 transcription factor in response to drug treatment (17-allylamino-demethoxygeldanamycin [17-AAG]). …”
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[18F]FDG PET-Based Radiomics and Machine Learning for the Assessment of Gliomas and Glioblastomas: A Systematic Review by Francesco Dondi, Roberto Gatta, Maria Gazzilli, Pietro Bellini, Gian Luca Viganò, Cristina Ferrari, Antonio Rosario Pisani, Giuseppe Rubini, Francesco Bertagna

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Gastric Adenocarcinoma Incidentally Detected by PET/CT with PSMA Ligands by Cesare Michele Iacovitti, Barbara Muoio, Marco Cuzzocrea, Gaetano Paone, Giorgio Treglia

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Extrapulmonary sarcoidosis presenting as myositis: A rare case by Niraj Bohania, Sumeet Singla, Jagriti Nahata, Pijush Kanti Nandi, Seema Daksh, S Anuradha

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Diagnostic Performance of Positron Emission Tomography/Computed Tomography Using Fluorine-18 Fluorodeoxyglucose in Detecting Locoregional Nodal Involvement in Patients with Anal Canal Cancer: A Systematic Review and Meta-Analysis by Carmelo Caldarella, Salvatore Annunziata, Giorgio Treglia, Ramin Sadeghi, Narjes Ayati, Luca Giovanella

“…The diagnostic performance of positron emission tomography using 18F-fluorodeoxyglucose (FDG-PET) in detecting nodal involvement in patients with anal canal cancer (ACC) has been investigated by several studies with conflicting results. …”
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Enhanced irradiation swelling resistance in low activation Ti8VCrMnFeCu2 high entropy alloys: Exploring the role of heterogeneous nanoparticles by Yao Yu, Xiao Liu, Qianqian Wang, Qigui Yang, Ye Dong, Te Zhu, Peng Zhang, Runsheng Yu, Mingpan Wan, Xingzhong Cao

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Editorial: Methods and applications of tumour metabolic imaging in the preclinical and clinical setting by Liangjie Lin, Zhiliang Wei, Zhiliang Wei, Jing Wang, Jing Wang, Nian Wang, Nian Wang, Nian Wang

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Case report: Detecting giant cell arteritis in [68Ga]Ga-DOTA-Siglec-9-PET/CT by Simon M. Petzinna, Jim Küppers, Benedikt Schemmer, Anna L. Kernder, Anna L. Kernder, Claus-Jürgen Bauer, Leon von der Emde, Babak Salam, Jörg H. W. Distler, Anja Winklbauer, Markus Essler, Valentin S. Schäfer

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Innovative applications and future trends of multiparametric PET in the assessment of immunotherapy efficacy by Tingting Qiao, Tingting Qiao, Zhaoping Cheng, Yanhua Duan

Subjects: “…multiparametric positron emission tomography…”
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The value of 18F⁃FDG PET in the diagnosis and differential diagnosis of Parkinson's disease and multiple system atrophy with parkinsonism⁃predominant by DU Xiao‐xiao, DONG Wan‐hui, LI Yi, SUN Zhi‐hui, FAN Kang‐li, ZHANG Ying

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Evaluation of three diagnostic algorithms to reduce normal scan rates, radiation exposure and costs in patients with suspected chronic coronary syndrome referred for 82Rb-Positron Emission Tomography (82Rb-PET) by Christian Müller, Damian Wild, Philip Haaf, Felix Mahfoud, Michael J Zellweger, Simon M Frey, Gabrielle Huré, Jan-Philipp Leibfarth, Kathrin Thommen, Melissa L Amrein, Ibrahim Schaefer, Klara Rumora, Igor G Schneider, Federico Caobelli

“…However, the efficacy and safety of these approaches remain unclear.Methods Three diagnostic algorithms based on PTP, as summarised in the 2019 European Society of Cardiology (ESC) CCS guidelines, were retrospectively applied to 1792 patients with suspected CCS referred for 82Rb-Positron Emission Tomography (82Rb-PET): (1) defer testing if PTP ≤5%; (2) defer if PTP <15%; and (3) defer if PTP ≤5% or PTP 5–15% and CACS 0. …”
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Micro–Positron Emission Tomography/Contrast-Enhanced Computed Tomography Imaging of Orthotopic Pancreatic Tumor–Bearing Mice Using the αβ Integrin Tracer Cu-Labeled Cyclam-RAFT-c(-RGDfK-) by Winn Aung, Zhao-Hui Jin, Takako Furukawa, Michael Claron, Didier Boturyn, Chizuru Sogawa, Atsushi B. Tsuji, Hidekatsu Wakizaka, Toshimitsu Fukumura, Yasuhisa Fujibayashi, Pascal Dumy, Tsuneo Saga

“…The purpose of this study was to develop a clinically relevant orthotopic xenotransplantation model of pancreatic cancer and to perform a preclinical evaluation of a new positron emission tomography (PET) imaging probe, 64 Cu-labeled cyclam-RAFT-c(-RGDfK-) 4 peptide ( 64 Cu-RAFT-RGD), using this model. …”
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High Detection Rates for Prostate-specific Membrane Antigen–avid Prostate Cancer Recurrence at Low Prostate-specific Antigen levels on Extended Axial Field-of-view Positron Emission Tomography/Computed Tomography by Sarah Thomas, Jason Callahan, Paul Conway, Daniel Moon, Hugh Morgan, Johanna Ingbritsen, Melissa Munro, Robert E. Ware, Phil Dundee, Rodney J. Hicks

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Click Synthesis and Biologic Evaluation of ()- and ()-2-Amino-3-[1-(2-[F]Fluoroethyl)-1-[1,2,3]Triazol-4-yl]Propanoic Acid for Brain Tumor Imaging with Positron Emission Tomography by Jonathan McConathy, Dong Zhou, Stephany E. Shockley, Lynne A. Jones, Elizabeth A. Griffin, Hsiaoju Lee, Susan J. Adams, Robert H. Mach

“…The ( R )- and ( S )-enantiomers of 2-amino-3-[1-(2-[ 18 F]fluoroethyl)-1 H -[1,2,3]triazol-4-yl]propanoic acid (4) were synthesized and evaluated in the rat 9L gliosarcoma brain tumor model using cell uptake assays, biodistribution studies, and micro-positron emission tomography (microPET). The ( R )- and ( S )-enantiomers of [ 18 F]4 were radiolabeled separately using the click reaction in 57% and 51% decay-corrected yields, respectively. ( S )-[ 18 F]4 was a substrate for cationic amino acid transport and, to a lesser extent, system L transport in vitro. …”
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Recent methods for the diagnosis and differentiation of ameloblastoma: a narrative review by Ke Hu, Xudong Zhang, Ruixue Chen, Xiangjun Li

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PET in neurotherapeutic discovery and development by Melissa Chassé, Neil Vasdev

Subjects: “…Positron emission tomography…”
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Associations between inflammation and striatal dopamine D2-receptor availability in aging by Vanessa Crine, Goran Papenberg, Jarkko Johansson, Carl-Johan Boraxbekk, Anders Wåhlin, Ulman Lindenberger, Martin Lövdén, Katrine Riklund, Lars Bäckman, Lars Nyberg, Nina Karalija

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Diagnostics of hepatocellular cancer: state-of-the-art by T. Yu. Danzanova, G. T. Sinyukova, P. I. Lepedatu

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Translation of PET radiotracers for cancer imaging: recommendations from the National Cancer Imaging Translational Accelerator (NCITA) consensus meeting by Martina A. McAteer, Daniel R. McGowan, Gary J. R. Cook, Hing Y. Leung, Tony Ng, James P. B. O’Connor, Luigi Aloj, Anna Barnes, Phil J. Blower, Kevin M. Brindle, John Braun, Craig Buckley, Daniel Darian, Paul Evans, Vicky Goh, David Grainger, Carol Green, Matt G. Hall, Thomas A. Harding, Catherine D. G. Hines, Simon J. Hollingsworth, Penny L. Hubbard Cristinacce, Rowland O. Illing, Martin Lee, Baptiste Leurent, Sue Mallett, Radhouene Neji, Natalia Norori, Nora Pashayan, Neel Patel, Kieran Prior, Thomas Reiner, Adam Retter, Alasdair Taylor, Jasper van der Aart, Joseph Woollcott, Wai-Lup Wong, Jan van der Meulen, Shonit Punwani, Geoff S. Higgins

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