Evaluation of Bone Mineral Metabolism in Pre-Dialysis Chronic Kidney Disease: Quantitative Computed Tomography vs. Dual-Energy Absorptiometry and Correlation with Bone Turnover Mar... by Aydan Mutis Alan, Zehra Sezer, Ahmet Oz, Cebrail Karaca, Mevlüt Tamer Dinçer, Ahmet Murt, Fatma Beyza Sag, Selma Alagoz, Serdar Sahin, Mustafa Sait Gonen, Elif Güzel, Sinan Trabulus, Nurhan Seyahi

“…Additionally, DXA may overestimate lumbar spine BMD in this population, and the strong negative correlation between TRACP5b levels and the DXA L1–L4 Z-score highlights the potential role of biochemical markers in assessing bone status in CKD…”
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Antiviral efficacy of fluoxetine in early symptomatic COVID-19: an open-label, randomised, controlled, adaptive platform trial (PLATCOV)Research in context by Podjanee Jittamala, Simon Boyd, William H.K. Schilling, James A. Watson, Thundon Ngamprasertchai, Tanaya Siripoon, Viravarn Luvira, Elizabeth M. Batty, Phrutsamon Wongnak, Lisia M. Esper, Pedro J. Almeida, Cintia Cruz, Fernando R. Ascencao, Renato S. Aguiar, Najia K. Ghanchi, James J. Callery, Shivani Singh, Varaporn Kruabkontho, Thatsanun Ngernseng, Jaruwan Tubprasert, Wanassanan Madmanee, Kanokon Suwannasin, Amornrat Promsongsil, Borimas Hanboonkunupakarn, Kittiyod Poovorawan, Manus Potaporn, Attasit Srisubat, Bootsakorn Loharjun, Walter R.J. Taylor, Farah Qamar, Abdul Momin Kazi, M. Asim Beg, Danoy Chommanam, Sisouphanh Vidhamaly, Kesinee Chotivanich, Mallika Imwong, Sasithon Pukrittayakamee, Arjen M. Dondorp, Nicholas P.J. Day, Mauro M. Teixeira, Watcharapong Piyaphanee, Weerapong Phumratanaprapin, Nicholas J. White

“…Measurements were taken daily between days 0 and 7 and analysed in a modified intention-to-treat population (>2 days follow-up).The viral clearance rate was estimated under a Bayesian hierarchical linear model fitted to the log10 viral densities measured in standardised duplicate oropharyngeal swab eluates taken daily over one week (18 measurements per patient). …”
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Incident Heart Failure in Atherosclerotic Renal Artery Stenosis: A Post Hoc Analysis of the CORAL Trial by Rajesh Gupta, Michelle M. Estrella, Rebecca Scherzer, Pamela S. Brewster, Lance D. Dworkin, Hanh T. Nguyen, Yanmei Xie, Joachim H. Ix, Michael G. Shlipak, Timothy P. Murphy, Donald E. Cutlip, Eldrin F. Lewis, Christopher J. Cooper

“…The CORAL randomized controlled trial has the largest study population of participants with renal artery stenosis. …”
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4-1BB agonist targeted to fibroblast activation protein α synergizes with radiotherapy to treat murine breast tumor models by Ignacio Melero, Alvaro Teijeira, Christian Klein, Maria E Rodriguez-Ruiz, Christina Claus, Pablo Umana, Tamara Tanos, Carlos E De Andrea, Carlos Luri-Rey, Paloma Sanchez-Mateos, Leticia Fernández-Rubio, María Collantes, Irantzu Serrano-Mendioroz, Celia Barrio-Alonso, Antonio Rullan, Jon Ander Simon, Eneko Garate-Soraluze, Claudia del Pilar Herrero

“…Selective monoclonal antibody (mAb)-mediated depletions of immune cell populations, neutralizing interferon alpha/beta receptor 1 (IFNAR-I) IFNAR and interferon (IFN)-γ mAbs and gene-modified mice (4-1BB−/−) were used to delineate the immune cell subsets and mechanisms required for efficacy. 67Ga labeled muFAP-4-1BBL tracked by SPECT-CT was used to study biodistribution. …”
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Guideline: Neurorehabilitation in patients with disorder of consciousness. Recommendations from the Spanish Society of Neurorehabilitation by E. Noé, M.D. Navarro, B. Moliner, M. O’Valle, J. Olaya, A. Maza, R. Llorens, J. Ferri, R. Rodríguez, T. Pérez, M. Bernabéu, C. Colomer, A. Gómez, C. González, A. Juárez-Belaúnde, C. López, S. Laxe, R. Pelayo, M. Ríos, I. Quemada, Enrique Noé Sebastián, María Dolores Navarro Pérez, Belén Moliner Muñoz, Myrtha O’Valle Rodríguez, José Olaya Sanchez, Roberto Llorens Rodríguez, Anny Maza Pino, Joan Ferri Campos, Rubén Rodríguez Duarte, Teresa Pérez Nieves, Montserrat Bernabeu, Carolina Colomer Font, Antonio Gómez Blanco, Carlos González Alted, Alan Juárez Belaúnde, Cristina López Pascua, Sara Laxe García, Raúl Pelayo Vergara, Marcos Ríos Lago, Ignacio Quemada

“…These recommendations represent a consensus among experts and pertain to various aspects related to: 1) clinical assessment, 2) complementary diagnostic tests, 3) prognosis, and 4) treatment in this specific population. Resumen: Introducción: Guía para la práctica clínica en neurorrehabilitación de personas adultas en estado alterado de la consciencia (EAC) de la Sociedad Española de Neurorrehabilitación. …”
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Prevalence of potentially inappropriate prescribing in a subpopulation of older European clinical trial participants: a cross-sectional study by Manuel R Blum, Patricia M Kearney, Rose Galvin, Christine Baumgartner, Anette Van Dorland, Stephen Byrne, Nicolas Rodondi, Simon P Mooijaart, Carol Sinnott, Rosalinde K E Poortvliet, Jacobijn Gussekloo, David O Riordan, Carole Elodie Aubert, Kieran A Walsh, Robert S Du Puy, J Wouter Jukema, Vera McCarthy, Elaine K Walsh, Tinh-Hai Collet, Olaf M Dekkers

“…It demonstrated a significant difference in the prevalence of PPOs between the three populations. Further research is urgently needed into the impact of system level factors as this has important implications for patient safety, healthcare provision and economic costs.…”
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Prediction model for type 2 diabetes mellitus and its association with mortality using machine learning in three independent cohorts from South Korea, Japan, and the UK: a model de... by Hayeon Lee, Seung Ha Hwang, Seoyoung Park, Yunjeong Choi, Sooji Lee, Jaeyu Park, Yejun Son, Hyeon Jin Kim, Soeun Kim, Jiyeon Oh, Lee Smith, Damiano Pizzol, Sang Youl Rhee, Hyunji Sang, Jinseok Lee, Dong Keon Yon

“…Methods: We utilized data from three independent, large-scale, general population-based, and worldwide cohort studies. The Korean cohort (NHIS-NSC cohort; discovery cohort; n = 973,303), conducted between 1 January, 2002 and 31 December, 2013, was used for training and internal validation, whereas the Japanese cohort (JMDC cohort; validation cohort A; n = 12,143,715) and UK cohort (UK Biobank; validation cohort B; n = 416,656) were used for external validation. …”
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Transcriptomic Profiling and Tumor Microenvironment Classification Reveal Unique and Dynamic Immune Biology in HIV-Associated Kaposi Sarcoma by Jihua Yang, Ayse Ece Cali Daylan, Aleksei Shevkoplias, Ekaterina Postovalova, Meng Wang, Andrey Tyshevich, Matthew Lee, Hiba Narvel, Ksenia Zornikova, Nara Shin, Nikita Kotlov, Luca Paoluzzi, Changcheng Zhu, Balazs Halmos, Xingxing Zang, Haiying Cheng

“…It disproportionately affects populations facing health disparities. Although antiretroviral therapy (ART) has improved KS control in people with HIV (PWH), treatment options for advanced KS remain limited. …”
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Exploring the potential mediating role of systemic antibiotics in the association between early-life lower respiratory tract infections and asthma at age 5 in the CHILD study by Maria V. Medeleanu, Maria V. Medeleanu, Myrtha E. Reyna, Myrtha E. Reyna, Darlene L. Y. Dai, Geoffrey L. Winsor, Fiona S. L. Brinkman, Rahul Verma, Ella Nugent, Nashita Riaz, Elinor Simons, Piushkumar J. Mandhane, Piushkumar J. Mandhane, Meghan B. Azad, Meghan B. Azad, Stuart E. Turvey, Stuart E. Turvey, Theo J. Moraes, Theo J. Moraes, Padmaja Subbarao, Padmaja Subbarao, Padmaja Subbarao, Padmaja Subbarao, Padmaja Subbarao, Padmaja Subbarao

“…We aimed to explore the association between early-life LRTIs and systemic antibiotics on asthma development and the potential mediating role of antibiotics in this relationship.MethodsData were collected as part of the longitudinal, general Canadian population CHILD Study. LRTIs during the first 18 months of life were identified through parental symptom report at regular study visits. …”
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CAR-CIK vs. CAR-T: benchmarking novel cytokine-induced killer cells as solid tumor immunotherapy in ErbB2+ rhabdomyosarcoma by Laura M. Moser, Laura M. Moser, Laura M. Moser, Laura M. Moser, Laura M. Moser, Catrin Heim, Sebastian E. Koschade, Sebastian E. Koschade, Sebastian E. Koschade, Sebastian E. Koschade, Sebastian E. Koschade, Philipp Wendel, Philipp Wendel, Philipp Wendel, Philipp Wendel, Süleyman Bozkurt, Sabine Harenkamp, Hermann Kreyenberg, Hermann Kreyenberg, Michael Merker, Michael Merker, Christian Münch, Christian Münch, Christian Münch, Elise Gradhand, Meike Vogler, Meike Vogler, Meike Vogler, Evelyn Ullrich, Evelyn Ullrich, Evelyn Ullrich, Evelyn Ullrich, Evelyn Ullrich, Halvard Bönig, Halvard Bönig, Jan-Henning Klusmann, Jan-Henning Klusmann, Jan-Henning Klusmann, Jan-Henning Klusmann, Peter Bader, Peter Bader, Peter Bader, Peter Bader, Peter Bader, Winfried S. Wels, Winfried S. Wels, Winfried S. Wels, Eva Rettinger, Eva Rettinger, Eva Rettinger, Eva Rettinger, Eva Rettinger

“…CIK cells are a heterogenous population of predominantly T cells with a mixed natural killer (NK) phenotype and combine non-MHC-restricted cytotoxicity with potent anti-tumor capacity of the adaptive immune system. …”
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Cardio-metabolic-related plasma proteins reveal biological links between cardiovascular diseases and fragility fractures: a cohort and Mendelian randomisation investigationResearch... by Karl Michaëlsson, Rui Zheng, John A. Baron, Tove Fall, Alicja Wolk, Lars Lind, Jonas Höijer, Carl Brunius, Eva Warensjö Lemming, Olga E. Titova, Bodil Svennblad, Susanna C. Larsson, Shuai Yuan, Håkan Melhus, Liisa Byberg, Hannah L. Brooke

“…We primarily aimed to discover and replicate the association of 274 cardio-metabolic-related proteins with future rates of hip and any fracture in two separate population-based cohorts, with a total of 12,314 women and men. …”
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Presenting the model of antecedents affecting moral-emotional acting in education by arefeh kazemi malekmahmoudi, negin jabbari, kiomars niaz azari

“…The research method was descriptive-survey. The statistical population in the quantitative section included education managers of Golestan province; by stratified random sampling method, as many as 270 people. …”
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Presenting a model for the establishment and maintenance of expert human resources in the government organizations of Sistan and Baluchestan province by Majid Reza Dahmardeh, Vahid pourshahabi, Amin Reza Kamalian, Habibollah Salaerzehi

“…AbstractThe purpose of this research is to identify indicators and effective factors in the maintenance of expert human resources in deprived and less developed areas and their ranking, as well as to draw a model of maintenance with an ecological approach, centered on the government organizations of Sistan and Baluchistan province, which is applicable in terms of purpose; and Regarding the implementation method, it is survey based on structural equation modeling. The statistical population included 181 managers and experts of government organizations in Sistan and Baluchistan province, from which 123 people were selected as a sample using Cochran's method. …”
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The application of blockchain with a comparative approach and its impact on risk, flexibility and internal control evaluation by mohammadsadegh aminipoor, HamidReza GholamniaRoshan, azadeh kiapour, Iman Dadashi

“…This research is applicable in terms of purpose, and descriptive-analytical in terms of method and data collection method. The statistical population includes managers, senior experts, and employees of the Iranian Auditing Association and audit institutions, among which 306 people were obtained based on Cochran's formula. …”
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Presenting the evaluation model of financial technology policies in National Bank of Iran by Vahid moradi, changiz mohammadi zadeh, ali farhadi mahali

“…According to its purpose, the research method is applicable-developmental, mixed (qualitative-quantitative) in terms of implementation, and survey-cross-sectional in terms of nature and method. The statistical population of the research in the qualitative part includes 17 experienced managers of Melli Bank of Iran, selected by the purposeful sampling method; and in the quantitative part it includes the managers and experts of the Melli Bank of Iran, with the sample size of 156 people using Cohen's power analysis and using the simple random sampling method. …”
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Analysis of the impact of the quality of service to the elderly on their loyalty through a Memorable experience and satisfaction among the elderly in 5-star hotels in Mashhad. by tina ezazi, vajihe hoshyar

“…In terms of data collection, it is a field research using a questionnaire tool and based on structural equation modeling. The statistical population of the research is all seniors over 70 years of age who refer to 5-star hotels in Mashhad and have used that hotel at least 3 times, in uncertain volume. …”
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Representation of the perception of effective factors on the implementation of Eric Cheng's knowledge management model in secondary schools of West Azarbaijan province by parivash mohammadi gheshlagh

“…Research methodology The research method is applicable from the point of view of purpose, and qualitative phenomenology in terms of data collection. The statistical population includes principals of secondary schools in West Azarbaijan province in the academic year of 2021-2022. …”
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Identifying factors affecting the creation of brand identity in Iran's banking industry by Seyed Mahdi Saatchi, farzad asayesh, Sedighe Tootian Esfahani, Seyed Mahmood Hashemi

“…According to its purpose, the research method is applicable, and in terms of implementation, it is qualitative and based on the case study approach. The statistical population of this research includes Iranian banking industry experts who were senior managers of Bank Mellat in Tehran. …”
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Developing and presenting a mathematical model for the purpose of organizational culture architecture based on creating alignment between the strategic reference points of organiza... by Elyas hasanzadeh Shweili, Mir Mehrdad peidaie, Ali reza Rezghi Rostami

“…The research method is applicable-developmental in terms of its purpose, and exploratory in terms of its nature. The statistical population of the research includes 20 academic and organizational experts, and the sampling was done in a purposeful, judgmental and snowball manner, and the interviews continued until theoretical saturation was reached. …”
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Analysis of the focal relationship of level five leadership with school organizational excellence by Hosein Majooni, Siroos Ghanbari

“…AbstractThe aim of the present study was to investigate the focal relationship of level five leadership with organizational excellence of schools. The statistical population of the research included all the teachers of primary schools in Fars province in the academic year of 2020-2021, numbering 16,264 people. …”
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