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  1. 19241

    Exposure to Subclinical Doses of Fumonisins, Deoxynivalenol, and Zearalenone Affects Immune Response, Amino Acid Digestibility, and Intestinal Morphology in Broiler Chickens by Revathi Shanmugasundaram, Laharika Kappari, Mohammad Pilewar, Matthew K. Jones, Oluyinka A. Olukosi, Anthony Pokoo-Aikins, Todd J. Applegate, Anthony E. Glenn

    Published 2025-01-01
    “…Higher mycotoxin groups T2 to T6 had a reduction in the digestibility of amino acids methionine (<i>p</i> < 0.05), aspartate (<i>p</i> < 0.05), and serine (<i>p</i> < 0.05); a reduction in CD4+, CD8+ T-cell populations (<i>p</i> < 0.05) and an increase in T regulatory cell percentages in the spleen (<i>p</i> < 0.05); a decrease in splenic macrophage nitric oxide production and total IgA production (<i>p</i> < 0.05); and upregulated cytochrome P450-1A1 and 1A4 gene expression (<i>p</i> < 0.05). …”
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  2. 19242

    Heterosis and inbreeding depression in Aus Rice (Oryza sativa L.) for yield contributing traits by S. G. Sarna1, Ekhlaque Ahmad2 and A. K. M. Aminul Islam1*

    Published 2024-12-01
    “…All crosses showed significant ID for filled grains/panicle except P3 x P4 and P6 x P7. The F2 populations of P6 x P7 (14.55) showed the highest positive ID for 1000-grain weight. …”
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  3. 19243

    IDENTIFIKASI PIGMEN KLOROFIL DAN CELAH ENERGI PADA DAUN CINCAU (CYCLEA BARBATA) SEBAGAI FOTOSENSITIZER ALAMI UNTUK APLIKASI DSSC by Ismail Saleh, Wa Ode Nirwana Sari Halidun

    Published 2022-05-01
    “…Tanaman cincau (Cyclea barbata) merupakan tanaman yang populer di Indonesia. Tanaman ini sering digunakan pada industri makanan, minuman, farmasi, dan lain sebagainya. …”
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  4. 19244

    Translation and Validation of the Edinburgh Postnatal Depression Scale for Eritrea: A Screening Tool for Postpartum Depression in Primary Health Care Facilities by Gebregziabher NK, Netsereab TB, Alazar FA, Fessaha YG, Sium AH, Ghebrehiwet NK

    Published 2025-02-01
    “…The Edinburgh Postnatal Depression Scale (EPDS) was developed to be used as a self-report questionnaire for English-speaking populations to screen for postnatal depression. This study aims to translate, validate, and adapt the EPDS into Eritrean settings.Methods: This study employed a cross-sectional study design to evaluate the performance of the EPDS as a screening tool by using a sample of 380 mothers from four primary healthcare facilities. …”
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  5. 19245

    Depot-specific acetylation profiles of adipose tissues—therapeutic targets for metabolically unhealthy obesity by Haoyue Guo, Zhiyi Zhang, Juntao Yang, Jiangfeng Liu, Hongwei Lin, Ningbei Yin

    Published 2025-01-01
    “…Overlap analysis was performed between our datasets and previously published proteomic datasets in obesity populations. Additionally, differentially modified Kac sites on histones and their related enzymes were identified. …”
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  6. 19246

    Complex resistance of spring and winter bread wheat lines to biotic and abiotic stresses by I. F. Lapochkina, N. R. Gainullin, O. A. Baranova, N. M. Kovalenko, L. A. Marchenkova, O. V. Pavlova, O. V. Mitroshina

    Published 2021-12-01
    “…A highly resistant parental form of winter soft wheat from “Arsenal” collection 119/4-06rw (wheat-Ae. speltoides-rye hybrid 2n = 42) with group resistance to two spots, four medium-resistant genotypes to both isolates of tan spot from Kazakhstan and Omsk populations of the pathogen, as well as genotypes resistant to the Omsk isolate of P. triticirepentis (parental form 113/00i-4 and lines 1-16i, 6-16i, 9-16i) were isolated. …”
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  7. 19247

    Resistance exercise training improves disuse-induced skeletal muscle atrophy in humans: a meta-analysis of randomized controlled trials by Xian Guo, Yanbing Zhou, Xinxin Li, Jinhao Mu

    Published 2025-02-01
    “…Further research is needed to explore the effects of RET in more diverse populations and under various disuse conditions. More high-quality research will be required to demonstrate the aforementioned benefits conclusively.…”
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  8. 19248

    Overexpression of multiple cytochrome P450 genes with and without knockdown resistance mutations confers high resistance to deltamethrin in Culex quinquefasciatus by Saowanee Chamnanya, Benyapa Kiddela, Jassada Saingamsook, Woottichai Nachaiwieng, Nongkran Lumjuan, Pradya Somboon, Jintana Yanola

    Published 2025-01-01
    “…This study aimed to investigate the expression levels of cytochrome P450 genes and detect mutations of the vgsc gene in deltamethrin-resistant Cx. quinquefasciatus populations in Thailand. Methods Two field-collected strains of Cx. quinquefasciatus, Cq_SP and Cq_NiH, were selected with deltamethrin to generate the resistant strains Cq_SP-R and Cq_NiH-R, respectively. …”
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  9. 19249

    Workplace Health Promotion as a good solution to the negative impact of the financial crisis on healthcare systems by Francesco Chirico

    Published 2018-11-01
    “…In Greece, the recent austerity period imposed by the Troika has severely affected spending on healthcare services and the populations’ health has been referred to in the literature as ‘the Greek tragedy’ [2, 3]. …”
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  10. 19250

    Metal mixtures exposure with risk of elevated serum neurofilament light chain concentrations in U.S. general adults, NHANES 2013–2014 by Yan Wang, Keyi Zhang, Hao Li, Si Liu, Linyao Ying, Lu Xiang, Na Liang, Liangkai Chen, Lin Xiao, Gang Luo

    Published 2025-01-01
    “…However, the relationship between metal mixtures exposure and serum neurofilament light chain (sNfL) concentrations, a valuable non-invasive biomarker of neurodegenerative diseases, in general adult populations remains understudied and unclear. Objective: This study seeks to elucidate the potential impact of metal mixtures exposure on sNfL concentrations in a representative sample of U.S. general adults. …”
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  11. 19251

    Contribution of cuproptosis and immune-related genes to idiopathic pulmonary fibrosis disease by Chengji Jin, Jia Li, Qiaoyu Li, Lipeng Zhang, Shaomao Zheng, Qiong Feng, Yongjie Li, Yu Zheng, Qiuli Nie, Jin Liang, Jing Wang, Jing Wang

    Published 2025-02-01
    “…Finally, our single-cell sequencing data revealed that in patients with IPF, CXCL12 was highly expressed in the endothelial cell subset (ECs), while SPP1 exhibited high expression in multiple cellular populations. The expression of the CTSG showed statistically significant differences in monocyte macrophages.ConclusionThe research methodically depicted the intricate interplay among five cuproptosis-related genes, four immune-related hub genes, and IPF, offering new ideas for diagnosing and treating patients with IPF.…”
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  12. 19252

    Gut microbiota influence on lung cancer risk through blood metabolite mediation: from a comprehensive Mendelian randomization analysis and genetic analysis by Yizhao Du, Qin Wang, Zongmei Zheng, Hailun Zhou, Yang Han, Ao Qi, Lijing Jiao, Lijing Jiao, Yabin Gong

    Published 2024-09-01
    “…Metabolic pathway analysis revealed glutathione metabolism and glutamate metabolism are the pathways most enriched with significant metabolites related to LC.ConclusionThese findings underscore the importance of GM in the development of LC, with metabolites partly mediating this effect, and provide dietary and lifestyle recommendations for high-risk lung cancer populations.…”
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  13. 19253

    Real-life study on the effectiveness and safety of sofosbuvir/velpatasvir-based antiviral agents for hepatitis C eradication in Chinese patients by Jiayi Wang, Lingyao Du, Dongmei Zhang, Chen Zhou, Yilan Zeng, Miao Liu, Xing Cheng, Xiaona Song, Han Chen, Ning Han, Enqiang Chen, Hong Tang

    Published 2024-12-01
    “…Background: Hepatitis C virus (HCV) eradication with sofosbuvir/velpatasvir (SOF/VEL) represents a significant advancement, offering hope for eliminating the virus in diverse patient populations. But real-world data on its effectiveness and safety remains scarce for patients with chronic hepatitis C (CHC) in China, especially those with HCV GT3b, cirrhosis, hepato-cellular carcinoma (HCC), or HCV/hepatitis B (HBV), HCV/HIV, or HCV/HBV/HIV coinfection. …”
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  14. 19254

    Atrial fibrillation outcomes in patients from Asia and non-Asia countries: insights from GARFIELD-AF by Karen Pieper, Xian-hong Fang, Kai Sun, Ajay K Kakkar, Saverio Virdone, Shinya Goto, Gloria Kayani, Zhi-Cheng Jing, John Camm, Chun-Yan Cheng, Tian-Yu Lian, Xi-Jie Zhu, Xian-Mei Li

    Published 2025-02-01
    “…NOAC had evident benefits for reducing mortality and stroke across populations. Further studies on sociocultural impacts on OAC outcomes are needed.Trial registration number ClinicalTrials.gov NCT01090362.…”
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  15. 19255

    Associations of co-exposure to polycyclic aromatic hydrocarbons and vitamin D with early lung dysfunction: Mediating roles of metabolic score-visceral adiposity index by Baihao Lin, Wanlu Liu, Hank-Han Wang, Haixia Qian, Xinyu Zhu, Mengya Xu, Yuyu Zheng, Nada Alhazmi, Yansen Bai

    Published 2025-01-01
    “…Conclusions: Our findings indicated that vitamin D antagonizes the hazardous effects of PAHs on early lung dysfunction by metabolic alteration, providing new insight into the identification of the underlying high-risk populations and accessible prevention and intervention measures for attenuating PAH-induced lung dysfunction.…”
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  16. 19256

    Intratumoral BO-112 in combination with radiotherapy synergizes to achieve CD8 T-cell-mediated local tumor control by Helena Escuin-Ordinas, Ignacio Melero, Marisol Quintero, Jose Luis Perez-Gracia, Maite Alvarez, Maria E Rodriguez-Ruiz, Miguel F Sanmamed, Paloma Sanchez-Mateos, Inmaculada Rodríguez López, Irantzu Serrano-Mendioroz, Celia Barrio-Alonso, Eneko Garate-Soraluze, Victor Diaz Pascual, Leire Arbea Moreno

    Published 2023-01-01
    “…Depletions of immune cell populations and knockout mice for the IFNAR and BATF-3 genes were used to delineate the immune system requirements for efficacy.Results In cultures of TS/A breast cancer cells, the combination of irradiation and BO-112 showed more prominent features of immunogenic tumor cell death in terms of calreticulin exposure. …”
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  17. 19257
  18. 19258

    The associations of physical activity patterns and the triglyceride-glucose index in US adults: a secondary data analysis of NHANES (2007–2018) by JinYe Zhang, YiLin Yang, HaoNan Zheng, BoWen Bai, QianKun Yang, Li Zhang, YuTong Zhao, Jing Luo, Bin Yu

    Published 2025-01-01
    “…Abstract The triglyceride-glucose (TyG) index, a readily accessible surrogate biomarker for insulin resistance and metabolic health, has been extensively investigated across various ethnic populations. The critical role of physical activity (PA) in enhancing insulin sensitivity has been corroborated by numerous studies. …”
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  19. 19259
  20. 19260

    Rationale and design of a multicentre randomised controlled trial on circulating tumour DNA-guided neoadjuvant treatment strategy for locally advanced rectal cancer (CINTS-R) by Bin Wu, Yi Xiao, Xiao Zhang, Tao Xu, Qian Liu, Wei Fu, Yang An, Yongheng Li, Guole Lin, Huadan Xue, Guoju Wu, Jiaolin Zhou, Hongwei Yao, Zhenjun Wang, Weijie Chen, Junyang Lu, Guannan Zhang, Xiaoyuan Qiu

    Published 2025-02-01
    “…New strategies such as total neoadjuvant therapy (TNT) and neoadjuvant immunotherapy have shown great promise in certain patient populations. Currently, there is an urgent need to stratify patients before treatment to adopt the appropriate neoadjuvant strategies. …”
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